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The map label for this gene is zupT [H]

Identifier: 91212469

GI number: 91212469

Start: 3411908

End: 3412723

Strand: Direct

Name: zupT [H]

Synonym: UTI89_C3477

Alternate gene names: 91212469

Gene position: 3411908-3412723 (Clockwise)

Preceding gene: 91212467

Following gene: 91212471

Centisome position: 67.35

GC content: 52.82

Gene sequence:

>816_bases
TTGACGATCTGCCTGAAGGTGAAGATTTATAAGGAGTTGTCGATGTCAGTACCTCTCATTCTGACCATACTGGCGGGGGC
AGCCACGTTTATTGGCGCGTTTCTCGGCGTTCTCGGGCAAAAACCCTCGAACCGCTTACTGGCGTTTTCGCTAGGATTTG
CGGCGGGGATCATGTTGCTCATCTCATTAATGGAAATGCTTCCTGCCGCATTAGCCGCCGAAGGAATGTCGCCTGTGTTG
GGTTATGGAATGTTTATCTTCGGTCTGCTTGGCTATTTTGGCCTGGACCGCATGTTGCCACATGCGCATCCGCAGGATTT
AATGCAAAAATCGGTGCAGCCGTTGCCAAAATCGATCAAGCGCACAGCCATTCTGCTCACTCTCGGCATCAGTCTGCATA
ACTTCCCGGAAGGGATTGCCACCTTTGTCACGGCGAGCAGCAACCTGGAGCTGGGATTTGGCATCGCCCTGGCCGTAGCG
TTGCACAATATTCCTGAAGGTCTGGCGGTTGCAGGCCCGGTTTACGCTGCAACAGGATCGAAACGTACCGCGATTCTGTG
GGCGGGCATTTCCGGACTGGCTGAAATTCTCGGTGGCGTTCTGGCGTGGTTAATTCTTGGCAGCATGATTTCTCCGGTGG
TCATGGCGGCAATCATGGCGGCGGTTGCAGGAATTATGGTGGCGCTCTCCGTTGATGAATTAATGCCGCTCGCCAAAGAG
ATTGACCCCAATAATAACCCCAGCTATGGCGTGCTATGTGGAATGTCAGTGATGGGATTCAGTTTAGTGCTGCTACAAAC
GGCGGGAATTGGTTAA

Upstream 100 bases:

>100_bases
GATGATATCCTTAACTAAAGGTGTCATTTTGATATCCTCACAATACGCTTGTTCGGCGGAGTAAGAACCCGGATAACAAT
GATGATGATCATCAGTTATT

Downstream 100 bases:

>100_bases
AGACGATAATGACAGATGTTGCCCATTGCTAAAGGCAACATCTGTATCGTTATTAAAGATATTATTGATGCTTTTCAAAC
ACTTCTTTATCGGAGCGTTT

Product: zinc transporter ZupT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MTICLKVKIYKELSMSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLMEMLPAALAAEGMSPVL
GYGMFIFGLLGYFGLDRMLPHAHPQDLMQKSVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVA
LHNIPEGLAVAGPVYAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAAVAGIMVALSVDELMPLAKE
IDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG

Sequences:

>Translated_271_residues
MTICLKVKIYKELSMSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLMEMLPAALAAEGMSPVL
GYGMFIFGLLGYFGLDRMLPHAHPQDLMQKSVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVA
LHNIPEGLAVAGPVYAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAAVAGIMVALSVDELMPLAKE
IDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG
>Mature_270_residues
TICLKVKIYKELSMSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLMEMLPAALAAEGMSPVLG
YGMFIFGLLGYFGLDRMLPHAHPQDLMQKSVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVAL
HNIPEGLAVAGPVYAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAAVAGIMVALSVDELMPLAKEI
DPNNNPSYGVLCGMSVMGFSLVLLQTAGIG

Specific function: Mediates zinc uptake. May also transport other divalent cations [H]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily [H]

Homologues:

Organism=Homo sapiens, GI229577422, Length=153, Percent_Identity=32.0261437908497, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI229577418, Length=153, Percent_Identity=32.0261437908497, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1789419, Length=257, Percent_Identity=100, Blast_Score=498, Evalue=1e-142,
Organism=Drosophila melanogaster, GI24652846, Length=183, Percent_Identity=25.6830601092896, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 28136; Mature: 28005

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTICLKVKIYKELSMSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLL
CEEEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
ISLMEMLPAALAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQKSVQPLPKSIK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
RTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPVYAATGS
HHHHHHHCCCHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHCCCCC
KRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAAVAGIMVALSVDELMPLAKE
CCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TICLKVKIYKELSMSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLL
EEEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
ISLMEMLPAALAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQKSVQPLPKSIK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
RTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPVYAATGS
HHHHHHHCCCHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHCCCCC
KRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAAVAGIMVALSVDELMPLAKE
CCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA