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The map label for this gene is qseC [H]

Identifier: 91212443

GI number: 91212443

Start: 3387840

End: 3389189

Strand: Direct

Name: qseC [H]

Synonym: UTI89_C3451

Alternate gene names: 91212443

Gene position: 3387840-3389189 (Clockwise)

Preceding gene: 91212442

Following gene: 91212447

Centisome position: 66.88

GC content: 52.81

Gene sequence:

>1350_bases
ATGAAATTTACCCAACGTCTTAGTCTGCGAGTCAGGCTGACGCTAATCTTTTTAATTCTGGCCTCGGTGACCTGGCTGCT
TTCCAGCTTTGTCGCCTGGAAACAAACAACGGATAACGTCGATGAGTTGTTCGACACCCAACTGATGCTGTTTGCCAAAC
GGTTAAGTACGCTCGATCTCAACGAAATCAACGCGGCGGATCGCATGGCACAGACGCCAAATAAATTAAAACACGGTCAT
GTTGATGACGATGCGCTGACTTTTGCCATCTTTACCCACGACGGCAGAATGGTCCTTAACGATGGCGATAACGGAGAAGA
TATTCCCTATAGCTATCAGCGGGAAGGTTTTGCTGACGGGCAACTGGTCGGTGAAGACGATCCCTGGCGTTTTGTCTGGA
TGACCTCACCTGATGGCAAATATCGCATCGTTGTGGGTCAGGAATGGGAATACCGTGAAGACATGGCGCTGGCGATTGTT
GCCGGACAATTGATCCCGTGGCTGGTCGCACTGCCGATTATGTTAATCATCATGATGGTACTACTGGGTCGTGAACTCGC
GCCGCTGAACAAATTGGCGCTGGCACTACGTATGCGTGACCCAGACTCGGAAAAACCACTAAACGCGACGGGCGTACCCA
GCGAAGTGCGCCCACTGGTTGAGTCGCTAAATCAACTGTTCGCCCGCACACATGCGATGATGGTTCGTGAACGACGCTTT
ACCTCCGACGCAGCTCACGAACTTCGTAGCCCGTTAACGGCGCTGAAAGTGCAAACCGAAGTTGCTCAGCTCTCTGACGA
TGATCCGCAGGCGCGGAAAAAAGCGCTGCTCCAATTACATTCCGGGATCGATCGCGCTACTCGTCTGGTTGATCAACTGC
TCACGCTATCGCGGCTGGACTCACTGGATAACCTTCAGGACGTCGCGGAGATCCCGCTTGAAGATCTCCTGCAATCGTCG
GTGATGGATATTTACCACACGGCGCAGCAGGCGAACATTGACGTGCGACTGACACTCAATGCCAACGGCATCAAACGCAC
CGGACAACCGCTATTGCTAAGTTTGTTGGTGCGAAATTTGCTGGATAACGCCGTGCGTTACAGTCCACAAGGTAGCGTGG
TAGACGTCACGCTGAATGCCGATAATTTCATCGTGAGGGATAACGGCCCCGGTGTGACGCCAGAGGCACTGGCGCGAATT
GGCGAACGCTTCTATCGCCCACCCGGACAAACCGCTACCGGCAGTGGACTTGGGCTATCGATTGTCCAGCGAATCGCCAA
GCTGCATGACATGAATGTTGAATTTGGGAATGCGGAACAAGGTGGATTTGAGGCGAAGGTAAGCTGGTAA

Upstream 100 bases:

>100_bases
CCAGTAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGCAGTGATTTTATTCGTACCGTGCATGGTATT
GGCTACACATTAGGTGAGAA

Downstream 100 bases:

>100_bases
CTTCTCTGTCTATGAGAGCCGTTAAAACGACTCTCATAGACTTTACTAATAGCAAAATATAAACCGTCCCCAAAAAAGCC
ACCAACCACAACCCAGACAA

Product: sensor protein QseC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MKFTQRLSLRVRLTLIFLILASVTWLLSSFVAWKQTTDNVDELFDTQLMLFAKRLSTLDLNEINAADRMAQTPNKLKHGH
VDDDALTFAIFTHDGRMVLNDGDNGEDIPYSYQREGFADGQLVGEDDPWRFVWMTSPDGKYRIVVGQEWEYREDMALAIV
AGQLIPWLVALPIMLIIMMVLLGRELAPLNKLALALRMRDPDSEKPLNATGVPSEVRPLVESLNQLFARTHAMMVRERRF
TSDAAHELRSPLTALKVQTEVAQLSDDDPQARKKALLQLHSGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQSS
VMDIYHTAQQANIDVRLTLNANGIKRTGQPLLLSLLVRNLLDNAVRYSPQGSVVDVTLNADNFIVRDNGPGVTPEALARI
GERFYRPPGQTATGSGLGLSIVQRIAKLHDMNVEFGNAEQGGFEAKVSW

Sequences:

>Translated_449_residues
MKFTQRLSLRVRLTLIFLILASVTWLLSSFVAWKQTTDNVDELFDTQLMLFAKRLSTLDLNEINAADRMAQTPNKLKHGH
VDDDALTFAIFTHDGRMVLNDGDNGEDIPYSYQREGFADGQLVGEDDPWRFVWMTSPDGKYRIVVGQEWEYREDMALAIV
AGQLIPWLVALPIMLIIMMVLLGRELAPLNKLALALRMRDPDSEKPLNATGVPSEVRPLVESLNQLFARTHAMMVRERRF
TSDAAHELRSPLTALKVQTEVAQLSDDDPQARKKALLQLHSGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQSS
VMDIYHTAQQANIDVRLTLNANGIKRTGQPLLLSLLVRNLLDNAVRYSPQGSVVDVTLNADNFIVRDNGPGVTPEALARI
GERFYRPPGQTATGSGLGLSIVQRIAKLHDMNVEFGNAEQGGFEAKVSW
>Mature_449_residues
MKFTQRLSLRVRLTLIFLILASVTWLLSSFVAWKQTTDNVDELFDTQLMLFAKRLSTLDLNEINAADRMAQTPNKLKHGH
VDDDALTFAIFTHDGRMVLNDGDNGEDIPYSYQREGFADGQLVGEDDPWRFVWMTSPDGKYRIVVGQEWEYREDMALAIV
AGQLIPWLVALPIMLIIMMVLLGRELAPLNKLALALRMRDPDSEKPLNATGVPSEVRPLVESLNQLFARTHAMMVRERRF
TSDAAHELRSPLTALKVQTEVAQLSDDDPQARKKALLQLHSGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQSS
VMDIYHTAQQANIDVRLTLNANGIKRTGQPLLLSLLVRNLLDNAVRYSPQGSVVDVTLNADNFIVRDNGPGVTPEALARI
GERFYRPPGQTATGSGLGLSIVQRIAKLHDMNVEFGNAEQGGFEAKVSW

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=449, Percent_Identity=98.8864142538975, Blast_Score=900, Evalue=0.0,
Organism=Escherichia coli, GI1790551, Length=276, Percent_Identity=32.2463768115942, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786783, Length=283, Percent_Identity=31.095406360424, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1786600, Length=258, Percent_Identity=29.8449612403101, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788279, Length=300, Percent_Identity=27, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787894, Length=457, Percent_Identity=27.1334792122538, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790861, Length=477, Percent_Identity=25.3668763102725, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789808, Length=248, Percent_Identity=26.6129032258064, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790346, Length=237, Percent_Identity=29.1139240506329, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788393, Length=240, Percent_Identity=28.3333333333333, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=30.1652892561983, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50245; Mature: 50245

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTQRLSLRVRLTLIFLILASVTWLLSSFVAWKQTTDNVDELFDTQLMLFAKRLSTLDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
NEINAADRMAQTPNKLKHGHVDDDALTFAIFTHDGRMVLNDGDNGEDIPYSYQREGFADG
HHCCHHHHHHCCCHHHCCCCCCCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCC
QLVGEDDPWRFVWMTSPDGKYRIVVGQEWEYREDMALAIVAGQLIPWLVALPIMLIIMMV
CEECCCCCEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGRELAPLNKLALALRMRDPDSEKPLNATGVPSEVRPLVESLNQLFARTHAMMVRERRF
HHCCCCCCHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
TSDAAHELRSPLTALKVQTEVAQLSDDDPQARKKALLQLHSGIDRATRLVDQLLTLSRLD
CHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
SLDNLQDVAEIPLEDLLQSSVMDIYHTAQQANIDVRLTLNANGIKRTGQPLLLSLLVRNL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHH
LDNAVRYSPQGSVVDVTLNADNFIVRDNGPGVTPEALARIGERFYRPPGQTATGSGLGLS
HHHHHEECCCCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHH
IVQRIAKLHDMNVEFGNAEQGGFEAKVSW
HHHHHHHHHHCCCCCCCCCCCCEEEEECC
>Mature Secondary Structure
MKFTQRLSLRVRLTLIFLILASVTWLLSSFVAWKQTTDNVDELFDTQLMLFAKRLSTLDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
NEINAADRMAQTPNKLKHGHVDDDALTFAIFTHDGRMVLNDGDNGEDIPYSYQREGFADG
HHCCHHHHHHCCCHHHCCCCCCCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCC
QLVGEDDPWRFVWMTSPDGKYRIVVGQEWEYREDMALAIVAGQLIPWLVALPIMLIIMMV
CEECCCCCEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGRELAPLNKLALALRMRDPDSEKPLNATGVPSEVRPLVESLNQLFARTHAMMVRERRF
HHCCCCCCHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
TSDAAHELRSPLTALKVQTEVAQLSDDDPQARKKALLQLHSGIDRATRLVDQLLTLSRLD
CHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
SLDNLQDVAEIPLEDLLQSSVMDIYHTAQQANIDVRLTLNANGIKRTGQPLLLSLLVRNL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHH
LDNAVRYSPQGSVVDVTLNADNFIVRDNGPGVTPEALARIGERFYRPPGQTATGSGLGLS
HHHHHEECCCCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHH
IVQRIAKLHDMNVEFGNAEQGGFEAKVSW
HHHHHHHHHHCCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]