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The map label for this gene is yghZ [H]

Identifier: 91212414

GI number: 91212414

Start: 3358723

End: 3359763

Strand: Direct

Name: yghZ [H]

Synonym: UTI89_C3422

Alternate gene names: 91212414

Gene position: 3358723-3359763 (Clockwise)

Preceding gene: 91212403

Following gene: 91212416

Centisome position: 66.3

GC content: 52.16

Gene sequence:

>1041_bases
ATGGTCTGGTTAGCGAATCCCGAACGTTACGGGCGGATGCAGTACCGCTATTGCGGAAAAAGTGGTTTACGCCTGCCCGC
GTTATCGCTCGGTTTATGGCACAATTTCGGTCACGTTAACGCGCTGGAATCACAGCGTGCGATCCTGCGTAAAGCGTTTG
ATTTAGGCATTACGCACTTTGATTTAGCCAACAATTACGGGCCGCCTCCAGGAAGCGCAGAAGAAAACTTTGGTCGCCTG
CTGCGCGAGGATTTTGCCGCTTATCGCGATGAACTGATTATCTCTACCAAAGCCGGATACGATATGTGGCCCGGTCCATA
CGGCTCTGGCGGCTCACGTAAATACCTGCTCGCCAGCCTCGACCAAAGCCTGAAGCGTATGGGGCTTGAGTATGTCGATA
TCTTTTACTCTCATCGCGTCGATGAAAATACGCCGATGGAAGAAACCGCCTCTGCGCTGGCTCATTCGGTACAAAGCGGT
AAGGCGCTGTATGTCGGGATCTCCTCTTACTCGCCAGAGCGGACGCAAAAAATGGTCGAGTTGCTGCGCGAGTGGAAAAT
TCCGCTGTTAATTCATCAACCTTCGTACAATTTACTGAACCGCTGGGTGGATAAAAGCGGCCTGCTGGATACCCTGCAAA
ATAACGGCGTGGGCTGCATTGCCTTTACTCCACTGGCTCAGGGATTGCTGACCGGAAAATATCTCAACGGTATTCCGCAA
GATTCACGGATGCATCGTGAAGGGAATAAAGTTCGTGGTCTGACGCCGAAAATGCTCACCGAAGCCAACCTCAACAGCCT
GCGCTTATTGCATGAAATGGCACAGCAGCGTGGACAATCAATGGCGCAAATGGCGTTAAGCTGGTTGCTGAAAGATGAGC
GAGTGACGTCGGTATTGATTGGTGCCAGCCGCGCGGAGCAACTTGAGGAGAACGTGCAGGCGCTGAATAATCTGACATTT
AGCACCGAGGAGCTGGCGCAGATTGATCAGCATATCGCCGATGGAGAGCTGAATCTGTGGCAGGCGTCTTCCGATAAATG
A

Upstream 100 bases:

>100_bases
CAGTTTTTCGTCACTCTGTGAGCCAGACTACGGGATACGCGCTGGCGAATCGCTAAACTAGAAACATTGTTTCGAAATTG
AATGGTGGAAAGGAGAGGTC

Downstream 100 bases:

>100_bases
CCTGTTAATAACGGGCGCGAGAACCGCGCCCGAATCAGATCAGTGATTATGACGAGTCAGTCGGTCAAGATAGCCCATCA
CAAATGCAGAGAGCACAAAC

Product: aldo-keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MVWLANPERYGRMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRL
LREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHSVQSG
KALYVGISSYSPERTQKMVELLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPQ
DSRMHREGNKVRGLTPKMLTEANLNSLRLLHEMAQQRGQSMAQMALSWLLKDERVTSVLIGASRAEQLEENVQALNNLTF
STEELAQIDQHIADGELNLWQASSDK

Sequences:

>Translated_346_residues
MVWLANPERYGRMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRL
LREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHSVQSG
KALYVGISSYSPERTQKMVELLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPQ
DSRMHREGNKVRGLTPKMLTEANLNSLRLLHEMAQQRGQSMAQMALSWLLKDERVTSVLIGASRAEQLEENVQALNNLTF
STEELAQIDQHIADGELNLWQASSDK
>Mature_346_residues
MVWLANPERYGRMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRL
LREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHSVQSG
KALYVGISSYSPERTQKMVELLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPQ
DSRMHREGNKVRGLTPKMLTEANLNSLRLLHEMAQQRGQSMAQMALSWLLKDERVTSVLIGASRAEQLEENVQALNNLTF
STEELAQIDQHIADGELNLWQASSDK

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI27436969, Length=329, Percent_Identity=35.5623100303951, Blast_Score=181, Evalue=6e-46,
Organism=Homo sapiens, GI4504825, Length=327, Percent_Identity=35.474006116208, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI27436964, Length=324, Percent_Identity=34.8765432098765, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI27436962, Length=324, Percent_Identity=34.8765432098765, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI27436966, Length=324, Percent_Identity=34.5679012345679, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI27436971, Length=326, Percent_Identity=33.7423312883436, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI41152114, Length=211, Percent_Identity=32.2274881516588, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI41327764, Length=213, Percent_Identity=30.9859154929577, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI223718702, Length=286, Percent_Identity=29.020979020979, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1789375, Length=346, Percent_Identity=98.5549132947977, Blast_Score=706, Evalue=0.0,
Organism=Escherichia coli, GI87081735, Length=330, Percent_Identity=35.7575757575758, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1789199, Length=348, Percent_Identity=29.0229885057471, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788070, Length=318, Percent_Identity=26.7295597484277, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788081, Length=323, Percent_Identity=23.8390092879257, Blast_Score=72, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=23.7388724035608, Blast_Score=82, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6323998, Length=329, Percent_Identity=24.6200607902736, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319958, Length=238, Percent_Identity=24.7899159663866, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322615, Length=238, Percent_Identity=24.3697478991597, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640980, Length=339, Percent_Identity=28.6135693215339, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI45549126, Length=339, Percent_Identity=28.6135693215339, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24646159, Length=334, Percent_Identity=25.4491017964072, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24646155, Length=328, Percent_Identity=26.219512195122, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR005399
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38915; Mature: 38915

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWLANPERYGRMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHF
CEECCCHHHHCCCHHEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEE
DLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASL
EHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHH
DQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHSVQSGKALYVGISSYSPERTQKMVE
HHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHH
LLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPQ
HHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCC
DSRMHREGNKVRGLTPKMLTEANLNSLRLLHEMAQQRGQSMAQMALSWLLKDERVTSVLI
CHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GASRAEQLEENVQALNNLTFSTEELAQIDQHIADGELNLWQASSDK
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCC
>Mature Secondary Structure
MVWLANPERYGRMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHF
CEECCCHHHHCCCHHEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEE
DLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASL
EHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHH
DQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHSVQSGKALYVGISSYSPERTQKMVE
HHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHH
LLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPQ
HHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCC
DSRMHREGNKVRGLTPKMLTEANLNSLRLLHEMAQQRGQSMAQMALSWLLKDERVTSVLI
CHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GASRAEQLEENVQALNNLTFSTEELAQIDQHIADGELNLWQASSDK
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]