Click here to switch to the map view.

The map label for this gene is nupG [H]

Identifier: 91212348

GI number: 91212348

Start: 3283222

End: 3284526

Strand: Direct

Name: nupG [H]

Synonym: UTI89_C3355

Alternate gene names: 91212348

Gene position: 3283222-3284526 (Clockwise)

Preceding gene: 91212347

Following gene: 91212351

Centisome position: 64.81

GC content: 50.04

Gene sequence:

>1305_bases
ATGTGCTTTTTCAAACACTCATCCGCATCACGATGTGAGGAAATTAACATGAATCTTAAGCTGCAGCTGAAAATCCTCTC
TTTTCTGCAGTTCTGTCTGTGGGGAAGTTGGCTGACGACCCTCGGCTCCTATATGTTTGTTACCCTGAAGTTTGACGGTG
CTTCTATTGGCGCAGTTTATAGTTCACTGGGTATCGCCGCGGTCTTTATGCCTGCGCTGCTGGGGATTGTGGCCGACAAA
TGGTTAAGTGCGAAATGGGTCTATGCCATTTGCCACACCATTGGCGCTATCACGCTGTTCATGGCGGCAGAGGTCACTAC
GCCGGAGGCGATGTTCCTTGTGATATTGATTAACTCGTTTGCTTATATGCCAACGCTTGGGTTAATCAACACCATCTCTT
ACTATCGCCTGCAAAATGCCGGGATGGATATCGTTACTGACTTCCCGCCAATCCGTATCTGGGGCACCATCGGCTTTATC
ATGGCAATGTGGGTGGTGAGCCTGTCCGGCTTCGAATTAAGCCACATGCAGCTGTATATTGGCGCAGCGCTTTCCGCCAT
TCTGGTTCTGTTTACCCTGACTCTGCCGCATATTCCGGTTGCTAAACAGCAAGCGAATCAGAGCTGGACAACCCTGCTGG
GCCTCGATGCATTCGCTCTGTTTAAAAACAAGCGTATGGCAATCTTCTTCATCTTCTCAATGCTGCTGGGCGCGGAACTG
CAGATTACCAACATGTTCGGTAATACCTTCCTGCACAGCTTCGACAAAGATCCGATGTTTGCCAGCAGCTTCATCGTGCA
GCATGCGTCAATCATCATGTCGATTTCGCAGATCTCTGAAACCCTGTTCATTCTGACCATCCCGTTCTTCTTAAGCCGCT
ACGGTATTAAGAACGTAATGATGATCAGTATTGTGGCGTGGATCCTGCGTTTTGCTCTGTTTGCTTACGGCGACCCGACT
CCGTTCGGTACTGTACTGCTGGTACTGTCGATGATCGTTTACGGTTGCGCATTCGACTTCTTCAACATCTCTGGTTCGGT
GTTTGTCGAAAAAGAAGTTAGTCCGGCAATTCGCGCCAGCGCGCAGGGGATGTTCCTGATGATGACCAACGGCTTCGGCT
GTATCCTCGGCGGCATCGTGAGCGGTAAAGTGGTTGAGATGTACACCCAAAACGGCATTACCGACTGGCAGACCGTATGG
CTGATTTTCGCAGGTTACTCCGTGGTTCTGGCCTTCGCGTTCATGGCGATGTTCAAATATAAACACGTTCGTGTCCCGAC
AGGTACACAGACGGTTAGCCACTAA

Upstream 100 bases:

>100_bases
AATTTCGTTTTGCAAATTGGGAATGTTTGCAATTATTTGCCACAGGTAACAAAAAACCAGTCCGCGAAGTTGATAGAATC
GCATCATCTCGCACGGTCAA

Downstream 100 bases:

>100_bases
TTACGCAAAGAAAAACGGGTCGCCAGAAGGTGACCCGTTTTTTTATTCTTACTTCAACACATAACCGTACAACCGTTTCA
TGCCATTCGCATCGGTTTCG

Product: transport of nucleosides, permease

Products: NA

Alternate protein names: Nucleoside-transport system protein nupG [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MCFFKHSSASRCEEINMNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVYSSLGIAAVFMPALLGIVADK
WLSAKWVYAICHTIGAITLFMAAEVTTPEAMFLVILINSFAYMPTLGLINTISYYRLQNAGMDIVTDFPPIRIWGTIGFI
MAMWVVSLSGFELSHMQLYIGAALSAILVLFTLTLPHIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFSMLLGAEL
QITNMFGNTFLHSFDKDPMFASSFIVQHASIIMSISQISETLFILTIPFFLSRYGIKNVMMISIVAWILRFALFAYGDPT
PFGTVLLVLSMIVYGCAFDFFNISGSVFVEKEVSPAIRASAQGMFLMMTNGFGCILGGIVSGKVVEMYTQNGITDWQTVW
LIFAGYSVVLAFAFMAMFKYKHVRVPTGTQTVSH

Sequences:

>Translated_434_residues
MCFFKHSSASRCEEINMNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVYSSLGIAAVFMPALLGIVADK
WLSAKWVYAICHTIGAITLFMAAEVTTPEAMFLVILINSFAYMPTLGLINTISYYRLQNAGMDIVTDFPPIRIWGTIGFI
MAMWVVSLSGFELSHMQLYIGAALSAILVLFTLTLPHIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFSMLLGAEL
QITNMFGNTFLHSFDKDPMFASSFIVQHASIIMSISQISETLFILTIPFFLSRYGIKNVMMISIVAWILRFALFAYGDPT
PFGTVLLVLSMIVYGCAFDFFNISGSVFVEKEVSPAIRASAQGMFLMMTNGFGCILGGIVSGKVVEMYTQNGITDWQTVW
LIFAGYSVVLAFAFMAMFKYKHVRVPTGTQTVSH
>Mature_434_residues
MCFFKHSSASRCEEINMNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVYSSLGIAAVFMPALLGIVADK
WLSAKWVYAICHTIGAITLFMAAEVTTPEAMFLVILINSFAYMPTLGLINTISYYRLQNAGMDIVTDFPPIRIWGTIGFI
MAMWVVSLSGFELSHMQLYIGAALSAILVLFTLTLPHIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFSMLLGAEL
QITNMFGNTFLHSFDKDPMFASSFIVQHASIIMSISQISETLFILTIPFFLSRYGIKNVMMISIVAWILRFALFAYGDPT
PFGTVLLVLSMIVYGCAFDFFNISGSVFVEKEVSPAIRASAQGMFLMMTNGFGCILGGIVSGKVVEMYTQNGITDWQTVW
LIFAGYSVVLAFAFMAMFKYKHVRVPTGTQTVSH

Specific function: Transports nucleosides with a high affinity. Driven by a proton motive force [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli xapB and yegT [H]

Homologues:

Organism=Escherichia coli, GI87082192, Length=418, Percent_Identity=99.7607655502392, Blast_Score=843, Evalue=0.0,
Organism=Escherichia coli, GI1788745, Length=418, Percent_Identity=58.3732057416268, Blast_Score=478, Evalue=1e-136,
Organism=Escherichia coli, GI1788415, Length=417, Percent_Identity=30.2158273381295, Blast_Score=190, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR004740 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 48262; Mature: 48262

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCFFKHSSASRCEEINMNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVY
CCEECCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHH
SSLGIAAVFMPALLGIVADKWLSAKWVYAICHTIGAITLFMAAEVTTPEAMFLVILINSF
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
AYMPTLGLINTISYYRLQNAGMDIVTDFPPIRIWGTIGFIMAMWVVSLSGFELSHMQLYI
HHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GAALSAILVLFTLTLPHIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFSMLLGAEL
HHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCE
QITNMFGNTFLHSFDKDPMFASSFIVQHASIIMSISQISETLFILTIPFFLSRYGIKNVM
EEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
MISIVAWILRFALFAYGDPTPFGTVLLVLSMIVYGCAFDFFNISGSVFVEKEVSPAIRAS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHC
AQGMFLMMTNGFGCILGGIVSGKVVEMYTQNGITDWQTVWLIFAGYSVVLAFAFMAMFKY
CCCEEEEEECCCHHHHHHHHCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KHVRVPTGTQTVSH
CEEECCCCCCCCCC
>Mature Secondary Structure
MCFFKHSSASRCEEINMNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVY
CCEECCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHH
SSLGIAAVFMPALLGIVADKWLSAKWVYAICHTIGAITLFMAAEVTTPEAMFLVILINSF
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
AYMPTLGLINTISYYRLQNAGMDIVTDFPPIRIWGTIGFIMAMWVVSLSGFELSHMQLYI
HHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GAALSAILVLFTLTLPHIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFSMLLGAEL
HHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCE
QITNMFGNTFLHSFDKDPMFASSFIVQHASIIMSISQISETLFILTIPFFLSRYGIKNVM
EEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
MISIVAWILRFALFAYGDPTPFGTVLLVLSMIVYGCAFDFFNISGSVFVEKEVSPAIRAS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHC
AQGMFLMMTNGFGCILGGIVSGKVVEMYTQNGITDWQTVWLIFAGYSVVLAFAFMAMFKY
CCCEEEEEECCCHHHHHHHHCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KHVRVPTGTQTVSH
CEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3311747; 9278503 [H]