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The map label for this gene is xdhC [H]

Identifier: 91212246

GI number: 91212246

Start: 3182335

End: 3182814

Strand: Direct

Name: xdhC [H]

Synonym: UTI89_C3253

Alternate gene names: 91212246

Gene position: 3182335-3182814 (Clockwise)

Preceding gene: 91212245

Following gene: 91212248

Centisome position: 62.82

GC content: 50.83

Gene sequence:

>480_bases
ATGAATCACAGCGAAACAATTACCATCGAATGCACCATTAACGGGATGCCTTTTCAGCTTCACGCCGCGCCAGGAATGCC
GCTTTCGGAACTACTCCGAGAACAAGGGCTTCTTAGTGTCAAACAAGGTTGCTGCGTAGGCGAATGCGGTGCCTGTACGG
TGCTGGTCGACGGCACAGCAATAGACAGTTGCTTATTCCTTGCGGCCTGGGCTGAAGGAAAAGAGATCCGCACGCTGGAA
GGTGAAGCGAAAGGTGGAAAACTTTCTCATGTTCAACTGGCTTATGCGAAATCCGGCGCAGTGCAATGCGGGTTTTGTAC
GCCGGGCCTGATTATGGCTACCACGGCGATGCTGGCAAAACCACGCGAAAAACCATTAACCATTACGGAAATTCGTCGTG
GACTGGCGGGAAATCTTTGTCGCTGCACGGGGTATCAGATGATTGTAAATACAGTTCTGGATTGCGAGAAAACGAAGTAA

Upstream 100 bases:

>100_bases
CTTCATGGCGGGCCAGTAAAGAGTTTCGTCTGCATCTCATCCAGACGATGACCCAAAAAGTGATTAGCGAAGCCGTCGCC
GCGGCGGGGGGAAAATTGCA

Downstream 100 bases:

>100_bases
AAGGATATCCGGCCTGAATTCAGGCCGGATTCTCAGAGGTTATGTGTTTAACAACTCATATTTCTTAATCTTGCGATAGA
GCGTAGCAATGCCGATGCCC

Product: xanthine dehydrogenase subunit XdhC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MNHSETITIECTINGMPFQLHAAPGMPLSELLREQGLLSVKQGCCVGECGACTVLVDGTAIDSCLFLAAWAEGKEIRTLE
GEAKGGKLSHVQLAYAKSGAVQCGFCTPGLIMATTAMLAKPREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCEKTK

Sequences:

>Translated_159_residues
MNHSETITIECTINGMPFQLHAAPGMPLSELLREQGLLSVKQGCCVGECGACTVLVDGTAIDSCLFLAAWAEGKEIRTLE
GEAKGGKLSHVQLAYAKSGAVQCGFCTPGLIMATTAMLAKPREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCEKTK
>Mature_159_residues
MNHSETITIECTINGMPFQLHAAPGMPLSELLREQGLLSVKQGCCVGECGACTVLVDGTAIDSCLFLAAWAEGKEIRTLE
GEAKGGKLSHVQLAYAKSGAVQCGFCTPGLIMATTAMLAKPREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCEKTK

Specific function: Iron-sulfur subunit of the xanthine dehydrogenase complex [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789232, Length=159, Percent_Identity=98.1132075471698, Blast_Score=319, Evalue=6e-89,
Organism=Escherichia coli, GI1786480, Length=164, Percent_Identity=35.3658536585366, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1789246, Length=141, Percent_Identity=32.6241134751773, Blast_Score=64, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17540638, Length=138, Percent_Identity=41.304347826087, Blast_Score=95, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17539860, Length=141, Percent_Identity=35.4609929078014, Blast_Score=83, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI32566215, Length=141, Percent_Identity=34.7517730496454, Blast_Score=79, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24647197, Length=163, Percent_Identity=32.5153374233129, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24647195, Length=163, Percent_Identity=32.5153374233129, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24647199, Length=156, Percent_Identity=34.6153846153846, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24647201, Length=150, Percent_Identity=34, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17737937, Length=131, Percent_Identity=38.1679389312977, Blast_Score=73, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24647193, Length=156, Percent_Identity=33.974358974359, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: NA

Molecular weight: Translated: 16921; Mature: 16921

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
10.7 %Cys+Met (Translated Protein)
6.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
10.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHSETITIECTINGMPFQLHAAPGMPLSELLREQGLLSVKQGCCVGECGACTVLVDGTA
CCCCCEEEEEEEECCCCEEEECCCCCCHHHHHHHCCCHHHHCCCCCCCCCEEEEEEECCH
IDSCLFLAAWAEGKEIRTLEGEAKGGKLSHVQLAYAKSGAVQCGFCTPGLIMATTAMLAK
HHHHHHEEECCCCCEEEEECCCCCCCEEEEEEEEEECCCCEEECCCCCCHHHHHHHHHHC
PREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCEKTK
CCCCCEEHHHHHHHHCCCEEHHCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNHSETITIECTINGMPFQLHAAPGMPLSELLREQGLLSVKQGCCVGECGACTVLVDGTA
CCCCCEEEEEEEECCCCEEEECCCCCCHHHHHHHCCCHHHHCCCCCCCCCEEEEEEECCH
IDSCLFLAAWAEGKEIRTLEGEAKGGKLSHVQLAYAKSGAVQCGFCTPGLIMATTAMLAK
HHHHHHEEECCCCCEEEEECCCCCCCEEEEEEEEEECCCCEEECCCCCCHHHHHHHHHHC
PREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCEKTK
CCCCCEEHHHHHHHHCCCEEHHCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]