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The map label for this gene is mraW [H]

Identifier: 89256825

GI number: 89256825

Start: 1469967

End: 1470884

Strand: Reverse

Name: mraW [H]

Synonym: FTL_1541

Alternate gene names: 89256825

Gene position: 1470884-1469967 (Counterclockwise)

Preceding gene: 89256826

Following gene: 89256824

Centisome position: 77.58

GC content: 33.33

Gene sequence:

>918_bases
ATGCATTATTCAGTATTGTTGCAAGAGTCTATTAATGATTTAAATATTAATCCTCAAGGTATTTATATCGATGCAACCTT
TGGTAGAGGTGGACATTCAAAAGCTATTTTAAATAGGCTTACTACAGGGCGTTTGATAGCTTTTGATAAGGATCTTGATG
CTATCAGTTATGCTAGGGAAAATTTCCAGTTTAGTAATTTTGAGATAGTTCACGCAAGTTTTGCTAGTATTTATGACTAC
TGTTTACAACATAGTCTGCTTGGTAAAATTGATGGTATAATTATGGATCTTGGGGTTTCTTCACCGCAACTAGATAATGC
TGCTAGGGGTTTTAGTTTTACGCATAATGGACCACTAGATATGCGCATGGACGTTTCTAAAGGTATTACAGCTAGCCAAG
CTTTAGAAGAGTTATCGGTATATGATCTAAGTTATATATTTAAAGTTTATGGTGAGGAACGTTTTGCAAAAAAAATCGCA
TTACGTATAAAGGATTACATTCAACAAAATGGTAGTATTAGGACAACATTAGAACTTGCAGAGCTTATTCGTGCAACTAT
TGGTAAGAAAGAAAAGAAAAATCCAGCAACACGCTGTTTCCAAGCTTTGAGAATTTATGTTAATAATGAGCTTAAGGATT
TAGAAGCTTTGCTAGAAAATATTTTAGCAGTTATTAAATCTGGTGGTAGGATAGCTGCTATATCTTTTCATTCATTAGAA
GATAGAATTGTGAAACAGAAATTTAGCGCACTTATAAATCCAAAGCAAGAGCTTAACAGAATTACAAAGATGTTACCGCA
AGATAGTAGCCAGATAAAACTAAAATGGATTACAAAAAAATCCAAAGCTAATGAAGATGAGCTTAATCAAAATGTTCGCT
CAAGAAGTGCTATCTTAAGGGTGGTCGAAAAGTTATGA

Upstream 100 bases:

>100_bases
ACTATTTTAAAGTTATATCTATACCTAAACTTGGTTCTGGTAAAACTGATTTTTCAAAAGCTAAGAAGTTAACTAATGAA
TTAGTTAAGGCATAGTTTAG

Downstream 100 bases:

>100_bases
TGTTAACAAATCGTCAAATAAGGGTAAGATTATTTGAATCACTTAAAAATAGTTTCTTTAAAAAAACAGTTGGTATTTCT
TTTGCATTATTATTTATATT

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MHYSVLLQESINDLNINPQGIYIDATFGRGGHSKAILNRLTTGRLIAFDKDLDAISYARENFQFSNFEIVHASFASIYDY
CLQHSLLGKIDGIIMDLGVSSPQLDNAARGFSFTHNGPLDMRMDVSKGITASQALEELSVYDLSYIFKVYGEERFAKKIA
LRIKDYIQQNGSIRTTLELAELIRATIGKKEKKNPATRCFQALRIYVNNELKDLEALLENILAVIKSGGRIAAISFHSLE
DRIVKQKFSALINPKQELNRITKMLPQDSSQIKLKWITKKSKANEDELNQNVRSRSAILRVVEKL

Sequences:

>Translated_305_residues
MHYSVLLQESINDLNINPQGIYIDATFGRGGHSKAILNRLTTGRLIAFDKDLDAISYARENFQFSNFEIVHASFASIYDY
CLQHSLLGKIDGIIMDLGVSSPQLDNAARGFSFTHNGPLDMRMDVSKGITASQALEELSVYDLSYIFKVYGEERFAKKIA
LRIKDYIQQNGSIRTTLELAELIRATIGKKEKKNPATRCFQALRIYVNNELKDLEALLENILAVIKSGGRIAAISFHSLE
DRIVKQKFSALINPKQELNRITKMLPQDSSQIKLKWITKKSKANEDELNQNVRSRSAILRVVEKL
>Mature_305_residues
MHYSVLLQESINDLNINPQGIYIDATFGRGGHSKAILNRLTTGRLIAFDKDLDAISYARENFQFSNFEIVHASFASIYDY
CLQHSLLGKIDGIIMDLGVSSPQLDNAARGFSFTHNGPLDMRMDVSKGITASQALEELSVYDLSYIFKVYGEERFAKKIA
LRIKDYIQQNGSIRTTLELAELIRATIGKKEKKNPATRCFQALRIYVNNELKDLEALLENILAVIKSGGRIAAISFHSLE
DRIVKQKFSALINPKQELNRITKMLPQDSSQIKLKWITKKSKANEDELNQNVRSRSAILRVVEKL

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=345, Percent_Identity=34.7826086956522, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI165377202, Length=170, Percent_Identity=37.6470588235294, Blast_Score=102, Evalue=5e-22,
Organism=Escherichia coli, GI1786270, Length=311, Percent_Identity=46.3022508038585, Blast_Score=273, Evalue=8e-75,
Organism=Drosophila melanogaster, GI62472493, Length=334, Percent_Identity=35.0299401197605, Blast_Score=165, Evalue=4e-41,
Organism=Drosophila melanogaster, GI28571637, Length=334, Percent_Identity=35.0299401197605, Blast_Score=165, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 34486; Mature: 34486

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYSVLLQESINDLNINPQGIYIDATFGRGGHSKAILNRLTTGRLIAFDKDLDAISYARE
CCHHHEEHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHH
NFQFSNFEIVHASFASIYDYCLQHSLLGKIDGIIMDLGVSSPQLDNAARGFSFTHNGPLD
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHCCCCCCCCCCCC
MRMDVSKGITASQALEELSVYDLSYIFKVYGEERFAKKIALRIKDYIQQNGSIRTTLELA
EEECHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHH
ELIRATIGKKEKKNPATRCFQALRIYVNNELKDLEALLENILAVIKSGGRIAAISFHSLE
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHH
DRIVKQKFSALINPKQELNRITKMLPQDSSQIKLKWITKKSKANEDELNQNVRSRSAILR
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHH
VVEKL
HHHHC
>Mature Secondary Structure
MHYSVLLQESINDLNINPQGIYIDATFGRGGHSKAILNRLTTGRLIAFDKDLDAISYARE
CCHHHEEHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHH
NFQFSNFEIVHASFASIYDYCLQHSLLGKIDGIIMDLGVSSPQLDNAARGFSFTHNGPLD
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHCCCCCCCCCCCC
MRMDVSKGITASQALEELSVYDLSYIFKVYGEERFAKKIALRIKDYIQQNGSIRTTLELA
EEECHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHH
ELIRATIGKKEKKNPATRCFQALRIYVNNELKDLEALLENILAVIKSGGRIAAISFHSLE
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHH
DRIVKQKFSALINPKQELNRITKMLPQDSSQIKLKWITKKSKANEDELNQNVRSRSAILR
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHH
VVEKL
HHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA