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The map label for this gene is dtpA [H]

Identifier: 89256642

GI number: 89256642

Start: 1274601

End: 1275971

Strand: Reverse

Name: dtpA [H]

Synonym: FTL_1339

Alternate gene names: 89256642

Gene position: 1275971-1274601 (Counterclockwise)

Preceding gene: 89256643

Following gene: 89256641

Centisome position: 67.3

GC content: 31.44

Gene sequence:

>1371_bases
GTGCAGCATATAGAAGAAAAACAAAGAACAAAATATTTTATTTCATTATTTTTGTTACAATTATTTGAAAGGTTTAGTTT
TTTTGGTTTCTTTTATATCTTAATATTCTTCTGTATAAATAAGCTAAATCTTACAGAGTCGTATGCTTCAACTTTTGCAG
GTTCTTTTACTGCGCTTTGTTATGTTTTAAGCTCATTAGGGGGCTTTATTTCTGATAAGGCTTTAGGTGTTAGAAGAACC
TTAATAGCTGGAGGTATCTGTTTACTATTAGGATATTCATTATTATCAACTAGTGATATGCTAATGAATTTTTCTATTTA
TGTTGGGTTGGCAATGATTATCGTTGGAGCATGTTTATTTGTGCCTATGACTTTAAACAGTGTGTCTAGATTATATGCAG
GAGATCCAGCAAAATTAGACTCTATATATACTTATTTTAATATGACTAACAATATTGGGGCGTTATCAGGTGCTATTTTG
ATACCTTATTTAAGTAGTGCGAACTCTTACGGCTTAGAAAATAGACACTATGGAATTGCTTTAGGGGTGTGTGCTTGTGG
AGTATTATTAGCTCTTGGTAATATATTTATGAATAAAAAGCTATTTTCGACAATAGCAGCTCCTGTAGGCAAAAAAACAC
TTAGTTTTCAGCAGTTAGTTTTAGCTATAATAGGTATAATATTTTTTGTATCAGTAGTTACTGGATTACTTTATTTTAGT
AGTCTAATTATCATCGTGCTGGTTTTAGCAGTAGTTATGATTGTTGGCTATTTTATAAATATTACTTTTCAGCAAGATAA
AGAGTATCGCTTAAAAATGCTACTTTTATTAGTATTTATATTTTACGCAACAATATTCTTTATGACCTATGCTCAAAAGA
CAACATCATTTTTCTTATTTAATGTTCACCATGTGGATTTGAATGTTTTAGGTATTAAGCTAAATTCGCAAACTGTACCA
GGATTATTAAATACTTCAGGGATTTTAATTTTCTCTCCAATTCTTGCTATGTATTTTAACAAGATGGGTGATAGATTAAG
ATCAACTAGTAAGTTTGCTTTATGTTTATTATTTGCTGGTATATGTTACGCGTTTTTGTACTTTGTTTGTGTATTTAATG
ATCCTTCTTCAAAAGTTTCATTTTGGTGGGAAGTAGTAGCAGTTGGAGTATTTTTCTCATGGGCTGAGATTATGGCAACA
GCTGTTGGTTTATCTTTGATAACCCAACTTGTTCCTACTAAGGTAAGAGGCTTTTGTATGGGGATGTGGTTTTTAACTTG
GGCAGTTGGTATTAAGCTAGGAGCATACGTGGCTTCACTTTATGCTAGTAATAGAACACTCAAAGAGCTCTTTGCTAATT
GGGCAAACTAA

Upstream 100 bases:

>100_bases
GAAAGTAGTACTTTAAAGAGTAATAATTTAACACGATTTGCTGTTTGACTAGTTCAAATAGCTTTAAAACAGCTTGTCGC
TAATATGAGGAGGATGTTAA

Downstream 100 bases:

>100_bases
ATTTATTTATGTGGATTACTATTGTTACTGTAGCTGCTGCTTTTTCACTTCTAGTCCTAAAAAATAAAATTAATAATGTT
ATTTATAAATAGTATGGGAA

Product: proton-dependent oligopeptide transport (POT) family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MQHIEEKQRTKYFISLFLLQLFERFSFFGFFYILIFFCINKLNLTESYASTFAGSFTALCYVLSSLGGFISDKALGVRRT
LIAGGICLLLGYSLLSTSDMLMNFSIYVGLAMIIVGACLFVPMTLNSVSRLYAGDPAKLDSIYTYFNMTNNIGALSGAIL
IPYLSSANSYGLENRHYGIALGVCACGVLLALGNIFMNKKLFSTIAAPVGKKTLSFQQLVLAIIGIIFFVSVVTGLLYFS
SLIIIVLVLAVVMIVGYFINITFQQDKEYRLKMLLLLVFIFYATIFFMTYAQKTTSFFLFNVHHVDLNVLGIKLNSQTVP
GLLNTSGILIFSPILAMYFNKMGDRLRSTSKFALCLLFAGICYAFLYFVCVFNDPSSKVSFWWEVVAVGVFFSWAEIMAT
AVGLSLITQLVPTKVRGFCMGMWFLTWAVGIKLGAYVASLYASNRTLKELFANWAN

Sequences:

>Translated_456_residues
MQHIEEKQRTKYFISLFLLQLFERFSFFGFFYILIFFCINKLNLTESYASTFAGSFTALCYVLSSLGGFISDKALGVRRT
LIAGGICLLLGYSLLSTSDMLMNFSIYVGLAMIIVGACLFVPMTLNSVSRLYAGDPAKLDSIYTYFNMTNNIGALSGAIL
IPYLSSANSYGLENRHYGIALGVCACGVLLALGNIFMNKKLFSTIAAPVGKKTLSFQQLVLAIIGIIFFVSVVTGLLYFS
SLIIIVLVLAVVMIVGYFINITFQQDKEYRLKMLLLLVFIFYATIFFMTYAQKTTSFFLFNVHHVDLNVLGIKLNSQTVP
GLLNTSGILIFSPILAMYFNKMGDRLRSTSKFALCLLFAGICYAFLYFVCVFNDPSSKVSFWWEVVAVGVFFSWAEIMAT
AVGLSLITQLVPTKVRGFCMGMWFLTWAVGIKLGAYVASLYASNRTLKELFANWAN
>Mature_456_residues
MQHIEEKQRTKYFISLFLLQLFERFSFFGFFYILIFFCINKLNLTESYASTFAGSFTALCYVLSSLGGFISDKALGVRRT
LIAGGICLLLGYSLLSTSDMLMNFSIYVGLAMIIVGACLFVPMTLNSVSRLYAGDPAKLDSIYTYFNMTNNIGALSGAIL
IPYLSSANSYGLENRHYGIALGVCACGVLLALGNIFMNKKLFSTIAAPVGKKTLSFQQLVLAIIGIIFFVSVVTGLLYFS
SLIIIVLVLAVVMIVGYFINITFQQDKEYRLKMLLLLVFIFYATIFFMTYAQKTTSFFLFNVHHVDLNVLGIKLNSQTVP
GLLNTSGILIFSPILAMYFNKMGDRLRSTSKFALCLLFAGICYAFLYFVCVFNDPSSKVSFWWEVVAVGVFFSWAEIMAT
AVGLSLITQLVPTKVRGFCMGMWFLTWAVGIKLGAYVASLYASNRTLKELFANWAN

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787922, Length=442, Percent_Identity=30.5429864253394, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1789911, Length=448, Percent_Identity=29.4642857142857, Blast_Score=185, Evalue=7e-48,
Organism=Escherichia coli, GI1786927, Length=438, Percent_Identity=24.8858447488584, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790572, Length=453, Percent_Identity=24.5033112582781, Blast_Score=85, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 50798; Mature: 50798

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]