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The map label for this gene is pheA [H]

Identifier: 89256640

GI number: 89256640

Start: 1270781

End: 1271623

Strand: Reverse

Name: pheA [H]

Synonym: FTL_1336

Alternate gene names: 89256640

Gene position: 1271623-1270781 (Counterclockwise)

Preceding gene: 89256641

Following gene: 89256639

Centisome position: 67.07

GC content: 31.2

Gene sequence:

>843_bases
ATGATTAAAGTATCTTTTCAGGGCGAGCATGGAGCTTACTCTGAGCAAGCAATAACTAATTTTTTAGAGCAGCAGAATAT
AAAAGATTTTCAAACAGTTCCATGCTGGTCTTTTTCTGATGCTATTGAACATACTATAAGTGGCAAATCAAATTTTGTAA
TGATTCCTGTAGAAAATTCTTTAGCTGGTTCTGTTGTACCAGCATATGATGAGTTGATTAAGAGTAATCTAAAGGTTAAA
GCTGAGGTTGTTTTAAAAATAAAACATTGCTTGATGGGACTCAATGACGTCGAAATTTCGGAAATTGAAAGTGTGATATC
TCATCCTCAAGCATTATCACAATGTGCTAATAGTCTTAAAAAATTAAAGCTTACTCCTGAGGCATTTGTTGATACAGCGG
GAGCTGCTAAGTATATCTTTGAGAAAAATAAAAGAAATCACTTAGCTATTGCTGGAGAGTTAGCAGCTAAAACTTATGGA
CTAAAGATTTTTCAGCATGAGTTGGAAGATGAGCAATTTAATTATACACGTTTTTTATTGATGGGTTATGATGATATCAA
AGTTAACTCAGCTGATAATAAGTATAAGACAACTATAATATTTTCAGTTGAAGATAAATCTAATGCTTTAGTAAACACAT
TAAATGTTTTTGGTAAATATAATATTAACCTTACTAAGATAGAATCCCGTCCATCAAGAAATAGAGCATGGAATTATTTG
TTTTTTATCGATTTTGAGGGAAGCGATGATGATTTTAATGTACAGCAGGCATTACTTGAAGTTCTTAAAAAAAGTACATT
TCTAAAAGTTTTAGGTTCTTATAAGAGTTATCACTTTAGTTAG

Upstream 100 bases:

>100_bases
GATAATTATATCTAAGTAAATATTTCTATTTTTATCTTGTATTTCATAATGTATTATATTTTATTAGTTAAATCAGTTTT
TAATTTTAAGTAAGTATATT

Downstream 100 bases:

>100_bases
AAAGTTTTATTAATGAATTTAAGTAATGAGTTATAAAGTTAAGATTATTTATAGGGATGTTGCTAACCTAAAGATTTCTT
TAAATAAAGATGGTTTAGTA

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MIKVSFQGEHGAYSEQAITNFLEQQNIKDFQTVPCWSFSDAIEHTISGKSNFVMIPVENSLAGSVVPAYDELIKSNLKVK
AEVVLKIKHCLMGLNDVEISEIESVISHPQALSQCANSLKKLKLTPEAFVDTAGAAKYIFEKNKRNHLAIAGELAAKTYG
LKIFQHELEDEQFNYTRFLLMGYDDIKVNSADNKYKTTIIFSVEDKSNALVNTLNVFGKYNINLTKIESRPSRNRAWNYL
FFIDFEGSDDDFNVQQALLEVLKKSTFLKVLGSYKSYHFS

Sequences:

>Translated_280_residues
MIKVSFQGEHGAYSEQAITNFLEQQNIKDFQTVPCWSFSDAIEHTISGKSNFVMIPVENSLAGSVVPAYDELIKSNLKVK
AEVVLKIKHCLMGLNDVEISEIESVISHPQALSQCANSLKKLKLTPEAFVDTAGAAKYIFEKNKRNHLAIAGELAAKTYG
LKIFQHELEDEQFNYTRFLLMGYDDIKVNSADNKYKTTIIFSVEDKSNALVNTLNVFGKYNINLTKIESRPSRNRAWNYL
FFIDFEGSDDDFNVQQALLEVLKKSTFLKVLGSYKSYHFS
>Mature_280_residues
MIKVSFQGEHGAYSEQAITNFLEQQNIKDFQTVPCWSFSDAIEHTISGKSNFVMIPVENSLAGSVVPAYDELIKSNLKVK
AEVVLKIKHCLMGLNDVEISEIESVISHPQALSQCANSLKKLKLTPEAFVDTAGAAKYIFEKNKRNHLAIAGELAAKTYG
LKIFQHELEDEQFNYTRFLLMGYDDIKVNSADNKYKTTIIFSVEDKSNALVNTLNVFGKYNINLTKIESRPSRNRAWNYL
FFIDFEGSDDDFNVQQALLEVLKKSTFLKVLGSYKSYHFS

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=275, Percent_Identity=29.0909090909091, Blast_Score=145, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6324013, Length=296, Percent_Identity=28.0405405405405, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 31708; Mature: 31708

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVSFQGEHGAYSEQAITNFLEQQNIKDFQTVPCWSFSDAIEHTISGKSNFVMIPVENS
CEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCC
LAGSVVPAYDELIKSNLKVKAEVVLKIKHCLMGLNDVEISEIESVISHPQALSQCANSLK
CCCCCCHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHH
KLKLTPEAFVDTAGAAKYIFEKNKRNHLAIAGELAAKTYGLKIFQHELEDEQFNYTRFLL
HEECCHHHHHCCCCHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
MGYDDIKVNSADNKYKTTIIFSVEDKSNALVNTLNVFGKYNINLTKIESRPSRNRAWNYL
EECCCEEECCCCCCEEEEEEEEECCCCCHHHHHHHHHEEECEEEEEECCCCCCCCCEEEE
FFIDFEGSDDDFNVQQALLEVLKKSTFLKVLGSYKSYHFS
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIKVSFQGEHGAYSEQAITNFLEQQNIKDFQTVPCWSFSDAIEHTISGKSNFVMIPVENS
CEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCC
LAGSVVPAYDELIKSNLKVKAEVVLKIKHCLMGLNDVEISEIESVISHPQALSQCANSLK
CCCCCCHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHH
KLKLTPEAFVDTAGAAKYIFEKNKRNHLAIAGELAAKTYGLKIFQHELEDEQFNYTRFLL
HEECCHHHHHCCCCHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
MGYDDIKVNSADNKYKTTIIFSVEDKSNALVNTLNVFGKYNINLTKIESRPSRNRAWNYL
EECCCEEECCCCCCEEEEEEEEECCCCCHHHHHHHHHEEECEEEEEECCCCCCCCCEEEE
FFIDFEGSDDDFNVQQALLEVLKKSTFLKVLGSYKSYHFS
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]