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The map label for this gene is ndk [H]

Identifier: 89256619

GI number: 89256619

Start: 1247875

End: 1248297

Strand: Reverse

Name: ndk [H]

Synonym: FTL_1310

Alternate gene names: 89256619

Gene position: 1248297-1247875 (Counterclockwise)

Preceding gene: 89256620

Following gene: 89256618

Centisome position: 65.84

GC content: 36.17

Gene sequence:

>423_bases
ATGACTAAACAAAGAACTTTATCTATAATTAAGCCAGATGCTGTAGAGAAAAATGTAATTGGTGAGATCTATAGCCGTTT
TGAGAAAGCAGGATTAAGAATTATTGCAGCTAAAATGAAGCATTTGTCAAAAGCAGAAGCTGAAGGATTTTATGCAGTAC
ATAAAGATAGACCTTTTTTTAGTGCGCTTGTTGAGTTTATGATTTCAGGTCCTGTGATGATACAAGTTTTAGAAGGTGAA
AATGCAATAGCAAAAAACCGTGAGTTAATGGGTGCAACAAACCCTAAAGAAGCTAAAGCAGGCACTATTAGAGCCGATTT
TGCTGATAGTATCGATGCAAATGCAGTCCATGGCTCAGATGCAGAAGATACAGCAGCACAAGAGATAAGATATTTCTTTA
GTGATACTGAGATTTTCGGCTAA

Upstream 100 bases:

>100_bases
AGCAGCTATCGAAAATTCTAATAATTAGTCACTACTTTTGATATTTCATGAATAAAAGTGCTATAATTTGACTTAATTAA
CTATTGGAGAATAATTTAAA

Downstream 100 bases:

>100_bases
GATATAATCTGATCTAATAAATATTTAGGAGGAGATTGGAAATGAGTTGGTTAACTAGAGTAATTGGTAGAAGTCTTGGT
TTAGAAGCGCAGAAAAAAGA

Product: nucleoside diphosphate kinase

Products: NA

Alternate protein names: NDK; NDP kinase; Nucleoside-2-P kinase [H]

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MTKQRTLSIIKPDAVEKNVIGEIYSRFEKAGLRIIAAKMKHLSKAEAEGFYAVHKDRPFFSALVEFMISGPVMIQVLEGE
NAIAKNRELMGATNPKEAKAGTIRADFADSIDANAVHGSDAEDTAAQEIRYFFSDTEIFG

Sequences:

>Translated_140_residues
MTKQRTLSIIKPDAVEKNVIGEIYSRFEKAGLRIIAAKMKHLSKAEAEGFYAVHKDRPFFSALVEFMISGPVMIQVLEGE
NAIAKNRELMGATNPKEAKAGTIRADFADSIDANAVHGSDAEDTAAQEIRYFFSDTEIFG
>Mature_139_residues
TKQRTLSIIKPDAVEKNVIGEIYSRFEKAGLRIIAAKMKHLSKAEAEGFYAVHKDRPFFSALVEFMISGPVMIQVLEGEN
AIAKNRELMGATNPKEAKAGTIRADFADSIDANAVHGSDAEDTAAQEIRYFFSDTEIFG

Specific function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate [H]

COG id: COG0105

COG function: function code F; Nucleoside diphosphate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NDK family [H]

Homologues:

Organism=Homo sapiens, GI66392203, Length=135, Percent_Identity=42.962962962963, Blast_Score=125, Evalue=1e-29,
Organism=Homo sapiens, GI66392227, Length=135, Percent_Identity=42.962962962963, Blast_Score=125, Evalue=2e-29,
Organism=Homo sapiens, GI66392205, Length=135, Percent_Identity=42.962962962963, Blast_Score=125, Evalue=2e-29,
Organism=Homo sapiens, GI4505409, Length=135, Percent_Identity=42.962962962963, Blast_Score=125, Evalue=2e-29,
Organism=Homo sapiens, GI66392192, Length=135, Percent_Identity=42.962962962963, Blast_Score=125, Evalue=2e-29,
Organism=Homo sapiens, GI38045913, Length=135, Percent_Identity=42.2222222222222, Blast_Score=124, Evalue=2e-29,
Organism=Homo sapiens, GI4557797, Length=135, Percent_Identity=42.2222222222222, Blast_Score=124, Evalue=3e-29,
Organism=Homo sapiens, GI37693993, Length=136, Percent_Identity=39.7058823529412, Blast_Score=120, Evalue=3e-28,
Organism=Homo sapiens, GI4826862, Length=138, Percent_Identity=36.231884057971, Blast_Score=114, Evalue=4e-26,
Organism=Homo sapiens, GI37574614, Length=137, Percent_Identity=37.956204379562, Blast_Score=93, Evalue=9e-20,
Organism=Homo sapiens, GI7019465, Length=137, Percent_Identity=37.956204379562, Blast_Score=93, Evalue=9e-20,
Organism=Homo sapiens, GI5031951, Length=136, Percent_Identity=36.0294117647059, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI4505413, Length=136, Percent_Identity=33.0882352941176, Blast_Score=72, Evalue=1e-13,
Organism=Homo sapiens, GI30023828, Length=135, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=4e-13,
Organism=Homo sapiens, GI148839372, Length=137, Percent_Identity=33.5766423357664, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788866, Length=138, Percent_Identity=57.9710144927536, Blast_Score=179, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI17506807, Length=135, Percent_Identity=43.7037037037037, Blast_Score=125, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6322783, Length=135, Percent_Identity=40, Blast_Score=120, Evalue=7e-29,
Organism=Drosophila melanogaster, GI45549037, Length=136, Percent_Identity=42.6470588235294, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI18860097, Length=133, Percent_Identity=33.8345864661654, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001564
- InterPro:   IPR023005 [H]

Pfam domain/function: PF00334 NDK [H]

EC number: =2.7.4.6 [H]

Molecular weight: Translated: 15428; Mature: 15297

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00469 NDP_KINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKQRTLSIIKPDAVEKNVIGEIYSRFEKAGLRIIAAKMKHLSKAEAEGFYAVHKDRPFF
CCCCCCEEEECCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEEECCCCHH
SALVEFMISGPVMIQVLEGENAIAKNRELMGATNPKEAKAGTIRADFADSIDANAVHGSD
HHHHHHHHCCCEEEEEECCCCCHHHCCHHCCCCCCCCCCCCCEECCCCCCCCCCCCCCCC
AEDTAAQEIRYFFSDTEIFG
CCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TKQRTLSIIKPDAVEKNVIGEIYSRFEKAGLRIIAAKMKHLSKAEAEGFYAVHKDRPFF
CCCCCEEEECCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEEECCCCHH
SALVEFMISGPVMIQVLEGENAIAKNRELMGATNPKEAKAGTIRADFADSIDANAVHGSD
HHHHHHHHCCCEEEEEECCCCCHHHCCHHCCCCCCCCCCCCCEECCCCCCCCCCCCCCCC
AEDTAAQEIRYFFSDTEIFG
CCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA