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The map label for this gene is xasA [C]

Identifier: 89256605

GI number: 89256605

Start: 1235301

End: 1235801

Strand: Reverse

Name: xasA [C]

Synonym: FTL_1296

Alternate gene names: 89256605

Gene position: 1235801-1235301 (Counterclockwise)

Preceding gene: 89256606

Following gene: 89256604

Centisome position: 65.18

GC content: 34.73

Gene sequence:

>501_bases
ATGAATATAAATTCTAATCAAGATCAAGTTCTAGGTTTTAAAGATGTTACAATCATGGCTGTAACAGCTAATTTTGGTAT
TCGCTGGATACCTGTAGCAGCTTGTTTGGGAGCTTCAGCAATATTCTTTTGGATACTTGGGGCGGTGATGTTTTTCTTGC
CTTTGGTCATAATTGCAGTTCAGTTATCAAGAAAACATCCTGATGAAGGTGGTATTTATTCATGGACTGTTAGAGCCTTA
GGACAAAAGGCGGGTTTTATGGTGGCATGGTTATACTGGATGAATACGATTTTTTATTATCCAGCTGTACTTATCTTTTT
AGCTACTAACTTTGCATATTTTATAGGTCGACCTGATTTGGTTGATAATCATTATTATATAACGATAGTTGTTTTAGTAG
CTTTTTGGTTGGTTACGGTGATTAGTTTTTATGGTCTAAAAGCTAATAAATATCTAGTTGATATGGGAGGTGTTCTAGGC
TCTTTTTTACCTGCTTTATAG

Upstream 100 bases:

>100_bases
TCATATATTTATAATATACTCTTTGTAAATATTTTCTTATATATCTATTTTTTATTACATATAATAACGCTTAGCATATT
TTAAGATAAAGGTTTAGTAT

Downstream 100 bases:

>100_bases
CATATTTAATTGTAGGAAAAAGTGCTACAGATTTTTCTTTGGCTAATATGATTCCGCACGATAATATTTGGCATAACTTA
TCAACACTAACTATTATCAT

Product: amino acid antiporter

Products: L-glutamate [Cytoplasm]; 4-aminobutyrate [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MNINSNQDQVLGFKDVTIMAVTANFGIRWIPVAACLGASAIFFWILGAVMFFLPLVIIAVQLSRKHPDEGGIYSWTVRAL
GQKAGFMVAWLYWMNTIFYYPAVLIFLATNFAYFIGRPDLVDNHYYITIVVLVAFWLVTVISFYGLKANKYLVDMGGVLG
SFLPAL

Sequences:

>Translated_166_residues
MNINSNQDQVLGFKDVTIMAVTANFGIRWIPVAACLGASAIFFWILGAVMFFLPLVIIAVQLSRKHPDEGGIYSWTVRAL
GQKAGFMVAWLYWMNTIFYYPAVLIFLATNFAYFIGRPDLVDNHYYITIVVLVAFWLVTVISFYGLKANKYLVDMGGVLG
SFLPAL
>Mature_166_residues
MNINSNQDQVLGFKDVTIMAVTANFGIRWIPVAACLGASAIFFWILGAVMFFLPLVIIAVQLSRKHPDEGGIYSWTVRAL
GQKAGFMVAWLYWMNTIFYYPAVLIFLATNFAYFIGRPDLVDNHYYITIVVLVAFWLVTVISFYGLKANKYLVDMGGVLG
SFLPAL

Specific function: Probable Amino Acid Transporter. Involved In Extreme Acid Resistance. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 18621; Mature: 18621

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNINSNQDQVLGFKDVTIMAVTANFGIRWIPVAACLGASAIFFWILGAVMFFLPLVIIAV
CCCCCCCCCEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLSRKHPDEGGIYSWTVRALGQKAGFMVAWLYWMNTIFYYPAVLIFLATNFAYFIGRPDL
HHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VDNHYYITIVVLVAFWLVTVISFYGLKANKYLVDMGGVLGSFLPAL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNINSNQDQVLGFKDVTIMAVTANFGIRWIPVAACLGASAIFFWILGAVMFFLPLVIIAV
CCCCCCCCCEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLSRKHPDEGGIYSWTVRALGQKAGFMVAWLYWMNTIFYYPAVLIFLATNFAYFIGRPDL
HHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VDNHYYITIVVLVAFWLVTVISFYGLKANKYLVDMGGVLGSFLPAL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-aminobutyrate [Cytoplasm]; L-glutamate [Periplasm] [C]

Specific reaction: 4-aminobutyrate [Cytoplasm] + L-glutamate [Periplasm] = L-glutamate [Cytoplasm] + 4-aminobutyrate [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8366052 [H]