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The map label for this gene is pab [H]

Identifier: 89256574

GI number: 89256574

Start: 1204048

End: 1205811

Strand: Reverse

Name: pab [H]

Synonym: FTL_1262

Alternate gene names: 89256574

Gene position: 1205811-1204048 (Counterclockwise)

Preceding gene: 89256575

Following gene: 89256573

Centisome position: 63.6

GC content: 29.88

Gene sequence:

>1764_bases
ATGAGTAATAACCAATTACCACAATTTGCAATTCTTGAAGATACTCTAACTGATAAACAAAAATATTATTTTTATAATCC
GATTGCAGAGGTTATAGCTAATAGTAAGGAGACACTTGAGTTAGCTTTTTATCAATTAGAAAAGCTTCAGCAGCAAAGGT
TATATCTAGTTGGATATTTAAGCTATGAAGCCAGTTATTACCTTAATAATAATCTTTATGATTTACGTGATCCTGATGAT
AGTAAATTACTTCATTTTGTCGCTTTTAGTGATTACTCAAACGAAATTCCAGATGATTTAATTTCAGATAAAAACATAGA
TATGATGATAGATAGCCTTAATTTTGCAGACTATCAAAAAAGCTTTGACAAAGTTCAACAAGCACTTATCGATGGTGAAA
GCTATCAGATTAATTTAACTAAAAATATCTTAGCTACTACAAAGCTTACTAGCTATGAGTTGTACAATAAGCTCAAACAA
CAACAATCAGTTAAATATGCTGCATATTTACCATTTTTAAACCCAGATATAATATCAATATCACCTGAACTTTTCTTTAA
AAAAGATGCTGAAAATTTGGTTGTTAACCCAATGAAAGGTACAGCAAGGCTTACTGGCAATGAATTGAAAGATCTAAAGA
TATATCAAGAATTAGCCTTATGTGATAAAAATAGGGCAGAGAACTTAATAATTGTTGATCTTTTGCGTAATGATTTATCT
GCTATTGCAAAAACTCATACTGTTAAGGTAGATAAACTTTTCTCAATAGAGAAATACAAAAATCTACTACAAATGACTTC
GCAAATTTCAGCAAAAGTAGATAAACAAATATCTTTTAGGAAGATTCTAGATGGCTTATTTCCTTGTGGTTCGATTACAG
GAGCTCCTAAAAAACGAACTATGGAACTAATCAAACAAATAGAAAAAGGTAAAAGGGGAGTTTATACCGGAAGCATTGGC
TATATTATGCCAAATAATGATATGTGCTTTAATGTTGCTATTCGTACTATTCAAAAATATCGAGATAACTTACAAATTGG
CGTAGGTGGCGGTATCACGGTATATTCGGATGTACAGTCAGAATGGCAAGAAATGAATACCAAGATAAACTTTATACGCC
AAATTTATCAGCCAGATTTTTGCTTAATTGAGAGCCTTTATTACTGTAATCAATTTAGAGATTTAGAGCTACATTTAGAG
AGGCTTGAGGACTCTGCTAGACAGTTATTTTTTGATATTGATATTTGCAAGATTAGAGATCAACTATATGACTATGTAGA
GAAATTAACTGATGATAAAGAATATAAAATCCGTATAGAATATCATTATGATAAATCTATAATTATTGAGCATACTCAAA
TTGATACTACCAACCAACAAGCTATTAAGCTAATAATTTGTCCTGAGAAAATAAACTCAGCTAATAAATTATTTCAGCAC
AAAACTACTCATAACTCGACACGAGGCTTTTATACTCAAATGCATCAAAAGTATATTCAAGATAAAAATTGTGAACTTAT
TTATCTAAATGAAAAAGATAATATTACTGAAACTAGATTTCATAATATAATTATTGAGAAAAATGATAAATTCTACACGC
CAAAATTAGAAGATGGTGTTTTAGCCGGTATCGCGAGAAAATCATTAATCAAACAAGGTAAACTGCAAGCAAAAAGCCTA
AATTTAAATGATCTAAAAACCGCTGATAAAATATATCTTATCAATAGTGTTAGAGGTTTGATACCAGCGTATTTGGGGAT
TTAA

Upstream 100 bases:

>100_bases
GCTGAATACAAAAAATTAGATGGAATTATTTATATTGATGAAATCCCAATAACTACAACAGGTAAAACTAATAGAAAAAA
AATAAAAGAAATGATTAATC

Downstream 100 bases:

>100_bases
GATGGTTTTATATATCGATCATTATGATTCATTTAGTAGTACGATTGTCGATTATATAACTTATCTTGGCTATCAAGTGT
CGATGCTAAAAACTGATGAG

Product: chorismate binding family protein

Products: NA

Alternate protein names: P-aminobenzoic acid synthase; PABA synthase [H]

Number of amino acids: Translated: 587; Mature: 586

Protein sequence:

>587_residues
MSNNQLPQFAILEDTLTDKQKYYFYNPIAEVIANSKETLELAFYQLEKLQQQRLYLVGYLSYEASYYLNNNLYDLRDPDD
SKLLHFVAFSDYSNEIPDDLISDKNIDMMIDSLNFADYQKSFDKVQQALIDGESYQINLTKNILATTKLTSYELYNKLKQ
QQSVKYAAYLPFLNPDIISISPELFFKKDAENLVVNPMKGTARLTGNELKDLKIYQELALCDKNRAENLIIVDLLRNDLS
AIAKTHTVKVDKLFSIEKYKNLLQMTSQISAKVDKQISFRKILDGLFPCGSITGAPKKRTMELIKQIEKGKRGVYTGSIG
YIMPNNDMCFNVAIRTIQKYRDNLQIGVGGGITVYSDVQSEWQEMNTKINFIRQIYQPDFCLIESLYYCNQFRDLELHLE
RLEDSARQLFFDIDICKIRDQLYDYVEKLTDDKEYKIRIEYHYDKSIIIEHTQIDTTNQQAIKLIICPEKINSANKLFQH
KTTHNSTRGFYTQMHQKYIQDKNCELIYLNEKDNITETRFHNIIIEKNDKFYTPKLEDGVLAGIARKSLIKQGKLQAKSL
NLNDLKTADKIYLINSVRGLIPAYLGI

Sequences:

>Translated_587_residues
MSNNQLPQFAILEDTLTDKQKYYFYNPIAEVIANSKETLELAFYQLEKLQQQRLYLVGYLSYEASYYLNNNLYDLRDPDD
SKLLHFVAFSDYSNEIPDDLISDKNIDMMIDSLNFADYQKSFDKVQQALIDGESYQINLTKNILATTKLTSYELYNKLKQ
QQSVKYAAYLPFLNPDIISISPELFFKKDAENLVVNPMKGTARLTGNELKDLKIYQELALCDKNRAENLIIVDLLRNDLS
AIAKTHTVKVDKLFSIEKYKNLLQMTSQISAKVDKQISFRKILDGLFPCGSITGAPKKRTMELIKQIEKGKRGVYTGSIG
YIMPNNDMCFNVAIRTIQKYRDNLQIGVGGGITVYSDVQSEWQEMNTKINFIRQIYQPDFCLIESLYYCNQFRDLELHLE
RLEDSARQLFFDIDICKIRDQLYDYVEKLTDDKEYKIRIEYHYDKSIIIEHTQIDTTNQQAIKLIICPEKINSANKLFQH
KTTHNSTRGFYTQMHQKYIQDKNCELIYLNEKDNITETRFHNIIIEKNDKFYTPKLEDGVLAGIARKSLIKQGKLQAKSL
NLNDLKTADKIYLINSVRGLIPAYLGI
>Mature_586_residues
SNNQLPQFAILEDTLTDKQKYYFYNPIAEVIANSKETLELAFYQLEKLQQQRLYLVGYLSYEASYYLNNNLYDLRDPDDS
KLLHFVAFSDYSNEIPDDLISDKNIDMMIDSLNFADYQKSFDKVQQALIDGESYQINLTKNILATTKLTSYELYNKLKQQ
QSVKYAAYLPFLNPDIISISPELFFKKDAENLVVNPMKGTARLTGNELKDLKIYQELALCDKNRAENLIIVDLLRNDLSA
IAKTHTVKVDKLFSIEKYKNLLQMTSQISAKVDKQISFRKILDGLFPCGSITGAPKKRTMELIKQIEKGKRGVYTGSIGY
IMPNNDMCFNVAIRTIQKYRDNLQIGVGGGITVYSDVQSEWQEMNTKINFIRQIYQPDFCLIESLYYCNQFRDLELHLER
LEDSARQLFFDIDICKIRDQLYDYVEKLTDDKEYKIRIEYHYDKSIIIEHTQIDTTNQQAIKLIICPEKINSANKLFQHK
TTHNSTRGFYTQMHQKYIQDKNCELIYLNEKDNITETRFHNIIIEKNDKFYTPKLEDGVLAGIARKSLIKQGKLQAKSLN
LNDLKTADKIYLINSVRGLIPAYLGI

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=255, Percent_Identity=36.078431372549, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1787518, Length=258, Percent_Identity=25.968992248062, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786809, Length=236, Percent_Identity=21.1864406779661, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87082077, Length=201, Percent_Identity=24.3781094527363, Blast_Score=69, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=255, Percent_Identity=31.3725490196078, Blast_Score=134, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6324361, Length=303, Percent_Identity=30.6930693069307, Blast_Score=131, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR006805
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR015890
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR005802
- InterPro:   IPR006221 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind; PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 68295; Mature: 68164

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNQLPQFAILEDTLTDKQKYYFYNPIAEVIANSKETLELAFYQLEKLQQQRLYLVGYL
CCCCCCCCEEEEHHHHCCCCCEEEECHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEEEE
SYEASYYLNNNLYDLRDPDDSKLLHFVAFSDYSNEIPDDLISDKNIDMMIDSLNFADYQK
EEEEEEEECCCEEECCCCCCCCEEEEEEECCCCCCCCHHHHCCCCCEEEEECCCHHHHHH
SFDKVQQALIDGESYQINLTKNILATTKLTSYELYNKLKQQQSVKYAAYLPFLNPDIISI
HHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEE
SPELFFKKDAENLVVNPMKGTARLTGNELKDLKIYQELALCDKNRAENLIIVDLLRNDLS
CHHHEEECCCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHH
AIAKTHTVKVDKLFSIEKYKNLLQMTSQISAKVDKQISFRKILDGLFPCGSITGAPKKRT
HHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
MELIKQIEKGKRGVYTGSIGYIMPNNDMCFNVAIRTIQKYRDNLQIGVGGGITVYSDVQS
HHHHHHHHCCCCCEEECCEEEEECCCCCCHHHHHHHHHHHHCCEEEECCCCEEEEHHHHH
EWQEMNTKINFIRQIYQPDFCLIESLYYCNQFRDLELHLERLEDSARQLFFDIDICKIRD
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEECHHHHHHH
QLYDYVEKLTDDKEYKIRIEYHYDKSIIIEHTQIDTTNQQAIKLIICPEKINSANKLFQH
HHHHHHHHHCCCCCEEEEEEEEECCEEEEEEEECCCCCCCEEEEEECCHHCCCHHHHHHH
KTTHNSTRGFYTQMHQKYIQDKNCELIYLNEKDNITETRFHNIIIEKNDKFYTPKLEDGV
CCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCHHEEEEEEEECCCCEECCCCCCCH
LAGIARKSLIKQGKLQAKSLNLNDLKTADKIYLINSVRGLIPAYLGI
HHHHHHHHHHHHCCCEEECCCCHHCCCCCEEEEEHHHHHHHHHHHCC
>Mature Secondary Structure 
SNNQLPQFAILEDTLTDKQKYYFYNPIAEVIANSKETLELAFYQLEKLQQQRLYLVGYL
CCCCCCCEEEEHHHHCCCCCEEEECHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEEEE
SYEASYYLNNNLYDLRDPDDSKLLHFVAFSDYSNEIPDDLISDKNIDMMIDSLNFADYQK
EEEEEEEECCCEEECCCCCCCCEEEEEEECCCCCCCCHHHHCCCCCEEEEECCCHHHHHH
SFDKVQQALIDGESYQINLTKNILATTKLTSYELYNKLKQQQSVKYAAYLPFLNPDIISI
HHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEE
SPELFFKKDAENLVVNPMKGTARLTGNELKDLKIYQELALCDKNRAENLIIVDLLRNDLS
CHHHEEECCCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHH
AIAKTHTVKVDKLFSIEKYKNLLQMTSQISAKVDKQISFRKILDGLFPCGSITGAPKKRT
HHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
MELIKQIEKGKRGVYTGSIGYIMPNNDMCFNVAIRTIQKYRDNLQIGVGGGITVYSDVQS
HHHHHHHHCCCCCEEECCEEEEECCCCCCHHHHHHHHHHHHCCEEEECCCCEEEEHHHHH
EWQEMNTKINFIRQIYQPDFCLIESLYYCNQFRDLELHLERLEDSARQLFFDIDICKIRD
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEECHHHHHHH
QLYDYVEKLTDDKEYKIRIEYHYDKSIIIEHTQIDTTNQQAIKLIICPEKINSANKLFQH
HHHHHHHHHCCCCCEEEEEEEEECCEEEEEEEECCCCCCCEEEEEECCHHCCCHHHHHHH
KTTHNSTRGFYTQMHQKYIQDKNCELIYLNEKDNITETRFHNIIIEKNDKFYTPKLEDGV
CCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCHHEEEEEEEECCCCEECCCCCCCH
LAGIARKSLIKQGKLQAKSLNLNDLKTADKIYLINSVRGLIPAYLGI
HHHHHHHHHHHHCCCEEECCCCHHCCCCCEEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8472954 [H]