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The map label for this gene is dtpA [H]

Identifier: 89256569

GI number: 89256569

Start: 1195261

End: 1196802

Strand: Direct

Name: dtpA [H]

Synonym: FTL_1251

Alternate gene names: 89256569

Gene position: 1195261-1196802 (Clockwise)

Preceding gene: 89256568

Following gene: 89256571

Centisome position: 63.04

GC content: 35.15

Gene sequence:

>1542_bases
GTGACTATTAGTGATGTGACTCATTCGAAAAATAATAATATTACACCATTTTGGGTTCTTTGGACTTTGGAGTTATGGGA
GAGATTTGGTTATTATGGTCTACAAGCTATATTAGCTATATATTTTGCTAGAAAATTAGTTTTCAGTGATGCCGAAGCAA
TGTTAATTTTTGGTTCTTTTTCGGCATTATTATATGGAGGTCCATTAATCGGTGGTTGGATTGGCGATAGCTACCTTGGT
GCAAAGCGTACAATATTTATTGGCGCTGGGATTTTATTTTTATCATATATATCACTTAGTTTTAGTACATTTATTGCCGA
GTATCTAGGCAGTACAGAAAAGACGGTTGTTATGTACTCACTAGCTGGTGTTGCTATTGGTGGGGGTCTCTTTAAAGCTA
ACCCTACTTCTTTAATCTCTAAGTTATTTGAAAAAGGTGATCCTGCTTTAGATGGGGCTATGACACTATATTATATGGCT
ATTAATATTGGTTCTTTTGTATCTATGCTTCTTACCCCTATAGTAGCGGCTAAATATGGTTATCTTCATGCTTTTTTATG
TTCAGCTATTGGGATGTTTCTAGGATTAATTAGCTACACTATTTTCTATCCAAAAATTAAAAGAATCTCAACAGAAGCTG
GTAGACAGAAGATGTCTTGGTTTAAGGTTTTTGTGGTACTTTTAGGAGCTTGTATAGCAATCTTTATAATAGGTAATATA
CTTGAGAATACTACTTTGTGTACTAGTATAGTTGTTGTAATAGCGATACTTGCTTTGGTATATTTTTTTATACAAATGTT
GAAACAAGCTGAGCATGAAAGAAAAAGGATGATTGTAGCTTTGATATTAATTATTCAAGGAATTATCTTCTTTGTATTGT
ATCAGCAAATGCCTACTTCTCTTAATTTCTTTGCAGTTAATAATGTCGATCCTCACTTTTTAGGCATGAATGTACACGGT
GAGCAATGGCAGGTACTTAATCCTCTAGTAATAGTATTAATGTCACCAATTCTATCGGTTGTGTATAAGAAAATACCTGG
AACTCATGTCACAAAATTTTGTTTTGGTATGACTTTATGTGCATTAGCATTTTTAGTACTATACTTTCCACAATTTACCG
CGACTAATGGTGTAGTATCTGGTTGGTGGTTAGTTGCAAGTTACTTCTTCCAATCTACTGGTGAGCTTCTAATCTCAGCA
TTAGGTTTATCTATGGTTGCTGAACTATTCCCAAGAAATATGAGTGGTCTTGCACAAGGTATGTGGCTACTTACTACAAT
GGTGGCTGGTCCAATTGGTGGTTATGTAGGTGCTTTGACAGCTCCAGCAGCAGGTACTGTATTTACGAAGGTCGAAGGAC
TAGCTGTTTATGGTCATGTTTTTTTAACTATAGGTATTTTTGTCGCTGTAATTGCTGCTATTATGTGGATTGCTCGCGGA
TGGCTAAATGCTATTATCGAGAGTACTAGAGTACATTTTGTATCAGAAGGTACTCATGGTATGCACGAAGAGACTGCTGT
TTTACCTACACAAAATAATTAA

Upstream 100 bases:

>100_bases
CTATTCATTTCTAATTGTTTTTAAGTTTTAAATGCTCTATGATGATTTTTTGACCTTTTTAAAAAGGTTAACTTATATTG
TTTAAAATAGGAGAATAATT

Downstream 100 bases:

>100_bases
TCTTTTGCCTTTGGTTTTCTAACACTTTTATTTTGATGTATTTTTTGTCTAATTTTTTTAGCAAAATCATTCTTATTAGA
AGGTTTTTTGTTGTTATTGT

Product: proton-dependent oligopeptide transport (POT) family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MTISDVTHSKNNNITPFWVLWTLELWERFGYYGLQAILAIYFARKLVFSDAEAMLIFGSFSALLYGGPLIGGWIGDSYLG
AKRTIFIGAGILFLSYISLSFSTFIAEYLGSTEKTVVMYSLAGVAIGGGLFKANPTSLISKLFEKGDPALDGAMTLYYMA
INIGSFVSMLLTPIVAAKYGYLHAFLCSAIGMFLGLISYTIFYPKIKRISTEAGRQKMSWFKVFVVLLGACIAIFIIGNI
LENTTLCTSIVVVIAILALVYFFIQMLKQAEHERKRMIVALILIIQGIIFFVLYQQMPTSLNFFAVNNVDPHFLGMNVHG
EQWQVLNPLVIVLMSPILSVVYKKIPGTHVTKFCFGMTLCALAFLVLYFPQFTATNGVVSGWWLVASYFFQSTGELLISA
LGLSMVAELFPRNMSGLAQGMWLLTTMVAGPIGGYVGALTAPAAGTVFTKVEGLAVYGHVFLTIGIFVAVIAAIMWIARG
WLNAIIESTRVHFVSEGTHGMHEETAVLPTQNN

Sequences:

>Translated_513_residues
MTISDVTHSKNNNITPFWVLWTLELWERFGYYGLQAILAIYFARKLVFSDAEAMLIFGSFSALLYGGPLIGGWIGDSYLG
AKRTIFIGAGILFLSYISLSFSTFIAEYLGSTEKTVVMYSLAGVAIGGGLFKANPTSLISKLFEKGDPALDGAMTLYYMA
INIGSFVSMLLTPIVAAKYGYLHAFLCSAIGMFLGLISYTIFYPKIKRISTEAGRQKMSWFKVFVVLLGACIAIFIIGNI
LENTTLCTSIVVVIAILALVYFFIQMLKQAEHERKRMIVALILIIQGIIFFVLYQQMPTSLNFFAVNNVDPHFLGMNVHG
EQWQVLNPLVIVLMSPILSVVYKKIPGTHVTKFCFGMTLCALAFLVLYFPQFTATNGVVSGWWLVASYFFQSTGELLISA
LGLSMVAELFPRNMSGLAQGMWLLTTMVAGPIGGYVGALTAPAAGTVFTKVEGLAVYGHVFLTIGIFVAVIAAIMWIARG
WLNAIIESTRVHFVSEGTHGMHEETAVLPTQNN
>Mature_512_residues
TISDVTHSKNNNITPFWVLWTLELWERFGYYGLQAILAIYFARKLVFSDAEAMLIFGSFSALLYGGPLIGGWIGDSYLGA
KRTIFIGAGILFLSYISLSFSTFIAEYLGSTEKTVVMYSLAGVAIGGGLFKANPTSLISKLFEKGDPALDGAMTLYYMAI
NIGSFVSMLLTPIVAAKYGYLHAFLCSAIGMFLGLISYTIFYPKIKRISTEAGRQKMSWFKVFVVLLGACIAIFIIGNIL
ENTTLCTSIVVVIAILALVYFFIQMLKQAEHERKRMIVALILIIQGIIFFVLYQQMPTSLNFFAVNNVDPHFLGMNVHGE
QWQVLNPLVIVLMSPILSVVYKKIPGTHVTKFCFGMTLCALAFLVLYFPQFTATNGVVSGWWLVASYFFQSTGELLISAL
GLSMVAELFPRNMSGLAQGMWLLTTMVAGPIGGYVGALTAPAAGTVFTKVEGLAVYGHVFLTIGIFVAVIAAIMWIARGW
LNAIIESTRVHFVSEGTHGMHEETAVLPTQNN

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=376, Percent_Identity=25.531914893617, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1787922, Length=462, Percent_Identity=43.9393939393939, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI1789911, Length=485, Percent_Identity=40, Blast_Score=350, Evalue=9e-98,
Organism=Escherichia coli, GI1790572, Length=471, Percent_Identity=26.1146496815287, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1786927, Length=475, Percent_Identity=24.2105263157895, Blast_Score=132, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17541704, Length=390, Percent_Identity=25.1282051282051, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17569141, Length=167, Percent_Identity=26.9461077844311, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71987453, Length=167, Percent_Identity=28.7425149700599, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24639583, Length=330, Percent_Identity=27.2727272727273, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24639585, Length=330, Percent_Identity=27.2727272727273, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24639581, Length=329, Percent_Identity=27.0516717325228, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28571098, Length=362, Percent_Identity=25.9668508287293, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28571102, Length=362, Percent_Identity=25.9668508287293, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571100, Length=362, Percent_Identity=25.9668508287293, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 56326; Mature: 56194

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISDVTHSKNNNITPFWVLWTLELWERFGYYGLQAILAIYFARKLVFSDAEAMLIFGSF
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHH
SALLYGGPLIGGWIGDSYLGAKRTIFIGAGILFLSYISLSFSTFIAEYLGSTEKTVVMYS
HHHHHCCCEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
LAGVAIGGGLFKANPTSLISKLFEKGDPALDGAMTLYYMAINIGSFVSMLLTPIVAAKYG
HHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLHAFLCSAIGMFLGLISYTIFYPKIKRISTEAGRQKMSWFKVFVVLLGACIAIFIIGNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LENTTLCTSIVVVIAILALVYFFIQMLKQAEHERKRMIVALILIIQGIIFFVLYQQMPTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LNFFAVNNVDPHFLGMNVHGEQWQVLNPLVIVLMSPILSVVYKKIPGTHVTKFCFGMTLC
EEEEEECCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ALAFLVLYFPQFTATNGVVSGWWLVASYFFQSTGELLISALGLSMVAELFPRNMSGLAQG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
MWLLTTMVAGPIGGYVGALTAPAAGTVFTKVEGLAVYGHVFLTIGIFVAVIAAIMWIARG
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLNAIIESTRVHFVSEGTHGMHEETAVLPTQNN
HHHHHHHHHHHEEEECCCCCCCCCCEECCCCCC
>Mature Secondary Structure 
TISDVTHSKNNNITPFWVLWTLELWERFGYYGLQAILAIYFARKLVFSDAEAMLIFGSF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHH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HHHHHHHHHHHEEEECCCCCCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA