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The map label for this gene is ffh [H]

Identifier: 89256557

GI number: 89256557

Start: 1185342

End: 1186718

Strand: Direct

Name: ffh [H]

Synonym: FTL_1239

Alternate gene names: 89256557

Gene position: 1185342-1186718 (Clockwise)

Preceding gene: 89256556

Following gene: 89256558

Centisome position: 62.52

GC content: 35.66

Gene sequence:

>1377_bases
ATGTTTACTAGTTTATCAGAGAAATTACAATCGTCTTTTAAAAAGATAAAAGGCCAAACCTCTCTAACAGAGGAGAATAT
TCAATCAGCGCTGCGTGATATTAGGGTATCACTTTTAGAAGCTGATGTTGCCTTGCCAGTAGTTAAAAAATTTATAGCTA
ATATTAAAGAAAAAGCTATTGGCGAAGAAGTCAAAAAAAGTCTTACCCCAGATCAGACTTTTATTTCTTTTGTCAAAAAA
GAAATTGAAAAAGCACTCGGTGAAGAAGCTGTACCAATAAACCTAAAAACTCAGCCACCTGCTGTGATATTAATGGCTGG
TTTACAAGGTGCTGGTAAAACAACATCTACAGCTAAGCTGGCTAAATACTTAAAAGAGCAACACAAGAAAAAAGTCATGG
TAGTTAGTGCCGATGTCTATCGCCCTGCTGCTATCGACCAGCTAAGAACTTTAGTAAATAGTTTAAATGTTGAGTTTTTT
GAATCAGATGCTTCACAACAGCCAGAAGATATTGTAACAGCTGCGATAAAAACAGCAAAAACTAAACTCATAGATGTGCT
TATCATCGATACTGCTGGTAGATTGCACATAGATAATGATATGATGGATGAGATTAAACAAATCCACAAAATTGCTAAAC
CAATCGAAACGTTTTTTACAGTTGATAGTATGACTGGTCAAGATGCTGCAGTTACAGCTAAAGCATTTAATGACGCTTTA
GAGTTAACTGGCGTGATTTTGACAAAAACTGATGGTGATGCTAGAGGTGGTGCTGCTTTATCGATTCGAGAAATCACAGG
CAAACCAATCAAGTTTTTAGGTGTCGGTGAAAAGACTGATGCTTTAGAGCCATTCCACCCTGATAGAGTTGCTTCTAAGA
TTTTAGGTATGGGCGATGTTCTTAGCTTGATAGAGAGTATAGAACAAAAAACAGAAAAAAAATCTGCTGAACAACTAACT
AAAAAACTTAAAAGTGGTAAGAGCTTTGATTTAGAAGATTTCAAAGCACAAATCCAACAGATGAAGAAAATGGGTGGTGT
AGGTTCAATTATGTCTAAACTGCCAAATATGCCAGCAAATTTGCCAGGTGACGTTGGTGATGATATGTTTAAAAAAATTG
AAGCTATGATAGACTCGATGACTCCACTTGAACGTAAAAAACCAGAACTTATCAAGCATAGTAGAAAGCAGCGAATTATT
AAAGGATCTGGAACTACAATTCAAGATCTTAATAAACTACTTCAGCAACACACGCAAATGAAAAAAATGATGAAAAGCGT
TATTGGTAAAAAAGGTGGTATGGCAAACTTAATGAAACGTATGTCTGCTATGCAAGGTATGGCGAATATGCCAGGTCTTT
TTGGTAAAAGAAAATAA

Upstream 100 bases:

>100_bases
CTATTAGTGTTGTTTGTTAGATAGTATATTTTTTTTAAAAATGTTAATATTTTGTCTATTATAGATAATATACCCCTAAG
AGTTAGAAACTTATAGCGAT

Downstream 100 bases:

>100_bases
GTATATATAAAATATAAGGATATCAAAATCAATGATAGGTGATAAAAACTTTGATAAAGTTTCTAATATAAATATAAAAA
AGGAAAAAGTATTGATTCCT

Product: signal recognition particle protein, Ffh

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MFTSLSEKLQSSFKKIKGQTSLTEENIQSALRDIRVSLLEADVALPVVKKFIANIKEKAIGEEVKKSLTPDQTFISFVKK
EIEKALGEEAVPINLKTQPPAVILMAGLQGAGKTTSTAKLAKYLKEQHKKKVMVVSADVYRPAAIDQLRTLVNSLNVEFF
ESDASQQPEDIVTAAIKTAKTKLIDVLIIDTAGRLHIDNDMMDEIKQIHKIAKPIETFFTVDSMTGQDAAVTAKAFNDAL
ELTGVILTKTDGDARGGAALSIREITGKPIKFLGVGEKTDALEPFHPDRVASKILGMGDVLSLIESIEQKTEKKSAEQLT
KKLKSGKSFDLEDFKAQIQQMKKMGGVGSIMSKLPNMPANLPGDVGDDMFKKIEAMIDSMTPLERKKPELIKHSRKQRII
KGSGTTIQDLNKLLQQHTQMKKMMKSVIGKKGGMANLMKRMSAMQGMANMPGLFGKRK

Sequences:

>Translated_458_residues
MFTSLSEKLQSSFKKIKGQTSLTEENIQSALRDIRVSLLEADVALPVVKKFIANIKEKAIGEEVKKSLTPDQTFISFVKK
EIEKALGEEAVPINLKTQPPAVILMAGLQGAGKTTSTAKLAKYLKEQHKKKVMVVSADVYRPAAIDQLRTLVNSLNVEFF
ESDASQQPEDIVTAAIKTAKTKLIDVLIIDTAGRLHIDNDMMDEIKQIHKIAKPIETFFTVDSMTGQDAAVTAKAFNDAL
ELTGVILTKTDGDARGGAALSIREITGKPIKFLGVGEKTDALEPFHPDRVASKILGMGDVLSLIESIEQKTEKKSAEQLT
KKLKSGKSFDLEDFKAQIQQMKKMGGVGSIMSKLPNMPANLPGDVGDDMFKKIEAMIDSMTPLERKKPELIKHSRKQRII
KGSGTTIQDLNKLLQQHTQMKKMMKSVIGKKGGMANLMKRMSAMQGMANMPGLFGKRK
>Mature_458_residues
MFTSLSEKLQSSFKKIKGQTSLTEENIQSALRDIRVSLLEADVALPVVKKFIANIKEKAIGEEVKKSLTPDQTFISFVKK
EIEKALGEEAVPINLKTQPPAVILMAGLQGAGKTTSTAKLAKYLKEQHKKKVMVVSADVYRPAAIDQLRTLVNSLNVEFF
ESDASQQPEDIVTAAIKTAKTKLIDVLIIDTAGRLHIDNDMMDEIKQIHKIAKPIETFFTVDSMTGQDAAVTAKAFNDAL
ELTGVILTKTDGDARGGAALSIREITGKPIKFLGVGEKTDALEPFHPDRVASKILGMGDVLSLIESIEQKTEKKSAEQLT
KKLKSGKSFDLEDFKAQIQQMKKMGGVGSIMSKLPNMPANLPGDVGDDMFKKIEAMIDSMTPLERKKPELIKHSRKQRII
KGSGTTIQDLNKLLQQHTQMKKMMKSVIGKKGGMANLMKRMSAMQGMANMPGLFGKRK

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=445, Percent_Identity=32.1348314606742, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI226371618, Length=371, Percent_Identity=33.1536388140162, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI23308697, Length=318, Percent_Identity=26.4150943396226, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI295424842, Length=318, Percent_Identity=26.4150943396226, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI89061728, Length=159, Percent_Identity=35.8490566037736, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI1788963, Length=425, Percent_Identity=62.1176470588235, Blast_Score=547, Evalue=1e-157,
Organism=Escherichia coli, GI1789874, Length=265, Percent_Identity=36.6037735849057, Blast_Score=167, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI17539958, Length=441, Percent_Identity=28.1179138321995, Blast_Score=188, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI193206261, Length=318, Percent_Identity=27.6729559748428, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6325345, Length=448, Percent_Identity=34.8214285714286, Blast_Score=224, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6320498, Length=313, Percent_Identity=26.8370607028754, Blast_Score=96, Evalue=8e-21,
Organism=Drosophila melanogaster, GI17647949, Length=455, Percent_Identity=28.1318681318681, Blast_Score=185, Evalue=6e-47,
Organism=Drosophila melanogaster, GI24641198, Length=321, Percent_Identity=27.1028037383178, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 50312; Mature: 50312

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTSLSEKLQSSFKKIKGQTSLTEENIQSALRDIRVSLLEADVALPVVKKFIANIKEKAI
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEEVKKSLTPDQTFISFVKKEIEKALGEEAVPINLKTQPPAVILMAGLQGAGKTTSTAKL
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCCCCHHHHH
AKYLKEQHKKKVMVVSADVYRPAAIDQLRTLVNSLNVEFFESDASQQPEDIVTAAIKTAK
HHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHHH
TKLIDVLIIDTAGRLHIDNDMMDEIKQIHKIAKPIETFFTVDSMTGQDAAVTAKAFNDAL
HHHHHEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ELTGVILTKTDGDARGGAALSIREITGKPIKFLGVGEKTDALEPFHPDRVASKILGMGDV
HHHEEEEECCCCCCCCCCEEEEHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCHHHH
LSLIESIEQKTEKKSAEQLTKKLKSGKSFDLEDFKAQIQQMKKMGGVGSIMSKLPNMPAN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
LPGDVGDDMFKKIEAMIDSMTPLERKKPELIKHSRKQRIIKGSGTTIQDLNKLLQQHTQM
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
KKMMKSVIGKKGGMANLMKRMSAMQGMANMPGLFGKRK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MFTSLSEKLQSSFKKIKGQTSLTEENIQSALRDIRVSLLEADVALPVVKKFIANIKEKAI
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEEVKKSLTPDQTFISFVKKEIEKALGEEAVPINLKTQPPAVILMAGLQGAGKTTSTAKL
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCCCCHHHHH
AKYLKEQHKKKVMVVSADVYRPAAIDQLRTLVNSLNVEFFESDASQQPEDIVTAAIKTAK
HHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHHH
TKLIDVLIIDTAGRLHIDNDMMDEIKQIHKIAKPIETFFTVDSMTGQDAAVTAKAFNDAL
HHHHHEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ELTGVILTKTDGDARGGAALSIREITGKPIKFLGVGEKTDALEPFHPDRVASKILGMGDV
HHHEEEEECCCCCCCCCCEEEEHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCHHHH
LSLIESIEQKTEKKSAEQLTKKLKSGKSFDLEDFKAQIQQMKKMGGVGSIMSKLPNMPAN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
LPGDVGDDMFKKIEAMIDSMTPLERKKPELIKHSRKQRIIKGSGTTIQDLNKLLQQHTQM
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
KKMMKSVIGKKGGMANLMKRMSAMQGMANMPGLFGKRK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]