BacMap

Definition	Francisella tularensis subsp. holarctica LVS chromosome, complete genome.
Accession	NC_007880
Length	1,895,994

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The map label for this gene is sufC [H]

Identifier: 89256548

GI number: 89256548

Start: 1177163

End: 1177912

Strand: Reverse

Name: sufC [H]

Synonym: FTL_1229

Alternate gene names: 89256548

Gene position: 1177912-1177163 (Counterclockwise)

Preceding gene: 89256549

Following gene: 89256547

Centisome position: 62.13

GC content: 32.93

Gene sequence:

>750_bases
ATGTTGTTAGAAATTAAAGATTTACATGTAAGTGTTGGTGAACAAAAAAAACAAATACTAAAAGGATTAAACTTAACAGT
TAAAAAAGGTGAAGTCCATGCAATTATGGGACCAAATGGAGCTGGCAAAAGTACTTTAAGTAATGTTTTAGCTGGTAAAG
ATGGTTATGAAATTACTCAAGGTTCAATCACATTTGATGGTAAAGATTTAAATGATTTAAGTATCTCAGAAAGAGCTGCA
GCCGGCATATTTTTAAGCTTACAGTATCCAATTGAAATCCCTGGAGTTAGTAATGTGCAGTTCCTTAAAACCGCTTTAAA
TAGTATTAGAAAGCAAAATGGTGAAGATGAAATTGATGCAATTTCTTTTATGAAAAAACTAAAAGAGAATATGCAGGTAT
TAAAAATTGATCAAAAATATATGTCACGAGGAGTTAATGAAGGCTTCTCAGGTGGTGAGAAAAAACGTAATGAAATGCTG
CAACTTATGATGCTTGAGCCAAAATTAGCTATACTAGATGAAACTGATTCTGGTCTAGACATAGATGCTCTACAAGTAGT
ATCACAAGGGGCAAACAGTATGAGATCAGCAGACAGAAGCTTTTTAGTAATCACTCACTACCAAAGACTTCTAGATCATA
TTCAACCAGATTTTGTCCATGTTTTAGCAGATGGTAAAATAGTTAAGATTGGTGGAAAAGAGCTTGCTCTTGAATTAGAA
GAGAAAGGTTATTCTTGGTTAAACAGCTAA

Upstream 100 bases:

>100_bases
TTGAGTTTGCTGTTGAAGCTCATAAGCTTATGGAAGTCAGTCTAGAAGGTGCAGTTGGTTAAGCTATAAATTATATAATT
TGATAAAAAAGGTTTAAAAA

Downstream 100 bases:

>100_bases
AGGTTGCTAAAAATGTTAATAGATAATAAATCTCTGCCTACTACTAAACAAGAAAGCTGGAAGTATACAAATATTGCTTC
TATTTATGAGAAGAATAATA

Product: ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MLLEIKDLHVSVGEQKKQILKGLNLTVKKGEVHAIMGPNGAGKSTLSNVLAGKDGYEITQGSITFDGKDLNDLSISERAA
AGIFLSLQYPIEIPGVSNVQFLKTALNSIRKQNGEDEIDAISFMKKLKENMQVLKIDQKYMSRGVNEGFSGGEKKRNEML
QLMMLEPKLAILDETDSGLDIDALQVVSQGANSMRSADRSFLVITHYQRLLDHIQPDFVHVLADGKIVKIGGKELALELE
EKGYSWLNS

Sequences:

>Translated_249_residues
MLLEIKDLHVSVGEQKKQILKGLNLTVKKGEVHAIMGPNGAGKSTLSNVLAGKDGYEITQGSITFDGKDLNDLSISERAA
AGIFLSLQYPIEIPGVSNVQFLKTALNSIRKQNGEDEIDAISFMKKLKENMQVLKIDQKYMSRGVNEGFSGGEKKRNEML
QLMMLEPKLAILDETDSGLDIDALQVVSQGANSMRSADRSFLVITHYQRLLDHIQPDFVHVLADGKIVKIGGKELALELE
EKGYSWLNS
>Mature_249_residues
MLLEIKDLHVSVGEQKKQILKGLNLTVKKGEVHAIMGPNGAGKSTLSNVLAGKDGYEITQGSITFDGKDLNDLSISERAA
AGIFLSLQYPIEIPGVSNVQFLKTALNSIRKQNGEDEIDAISFMKKLKENMQVLKIDQKYMSRGVNEGFSGGEKKRNEML
QLMMLEPKLAILDETDSGLDIDALQVVSQGANSMRSADRSFLVITHYQRLLDHIQPDFVHVLADGKIVKIGGKELALELE
EKGYSWLNS

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9955963, Length=240, Percent_Identity=27.9166666666667, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI42741659, Length=243, Percent_Identity=30.0411522633745, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI9961250, Length=240, Percent_Identity=30.8333333333333, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI9961252, Length=240, Percent_Identity=30.8333333333333, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI4505771, Length=240, Percent_Identity=30.8333333333333, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI156105685, Length=230, Percent_Identity=31.304347826087, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI148612844, Length=218, Percent_Identity=31.651376146789, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI255708477, Length=218, Percent_Identity=31.651376146789, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI21536378, Length=222, Percent_Identity=27.027027027027, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI73747915, Length=226, Percent_Identity=28.7610619469027, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787972, Length=247, Percent_Identity=57.8947368421053, Blast_Score=301, Evalue=2e-83,
Organism=Escherichia coli, GI1788761, Length=181, Percent_Identity=28.7292817679558, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790525, Length=215, Percent_Identity=30.6976744186047, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789672, Length=191, Percent_Identity=25.6544502617801, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1787029, Length=209, Percent_Identity=24.8803827751196, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87081709, Length=217, Percent_Identity=25.8064516129032, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786319, Length=190, Percent_Identity=26.3157894736842, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1789891, Length=223, Percent_Identity=27.8026905829596, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788897, Length=212, Percent_Identity=26.8867924528302, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786253, Length=210, Percent_Identity=30, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787500, Length=247, Percent_Identity=27.9352226720648, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI87081791, Length=248, Percent_Identity=26.6129032258064, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI193202349, Length=236, Percent_Identity=30.0847457627119, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193211017, Length=225, Percent_Identity=32, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71996809, Length=225, Percent_Identity=32, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193211015, Length=225, Percent_Identity=32, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17533971, Length=218, Percent_Identity=27.9816513761468, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115533592, Length=229, Percent_Identity=27.5109170305677, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI212646699, Length=240, Percent_Identity=27.5, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25146777, Length=236, Percent_Identity=29.6610169491525, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71992290, Length=248, Percent_Identity=25.8064516129032, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17541710, Length=232, Percent_Identity=26.7241379310345, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115535101, Length=242, Percent_Identity=29.7520661157025, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI193209708, Length=233, Percent_Identity=27.4678111587983, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71992285, Length=224, Percent_Identity=28.125, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17558664, Length=222, Percent_Identity=29.2792792792793, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17567269, Length=236, Percent_Identity=30.0847457627119, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17565938, Length=222, Percent_Identity=27.027027027027, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17567265, Length=238, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71984940, Length=232, Percent_Identity=28.8793103448276, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323217, Length=227, Percent_Identity=29.5154185022026, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324498, Length=173, Percent_Identity=28.3236994219653, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6324985, Length=248, Percent_Identity=29.4354838709677, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281363262, Length=219, Percent_Identity=32.8767123287671, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24653245, Length=219, Percent_Identity=32.8767123287671, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI85726357, Length=220, Percent_Identity=28.6363636363636, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI85724864, Length=244, Percent_Identity=30.327868852459, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24580555, Length=244, Percent_Identity=30.327868852459, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI85816269, Length=244, Percent_Identity=30.327868852459, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24580553, Length=244, Percent_Identity=30.327868852459, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI17136662, Length=218, Percent_Identity=28.8990825688073, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641565, Length=218, Percent_Identity=27.5229357798165, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI28574744, Length=228, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161076684, Length=252, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24581617, Length=252, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24581615, Length=252, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI161076682, Length=252, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27459; Mature: 27459

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLEIKDLHVSVGEQKKQILKGLNLTVKKGEVHAIMGPNGAGKSTLSNVLAGKDGYEITQ
CEEEEEHHHCCCCHHHHHHHHCCCEEEECCCEEEEECCCCCCHHHHHHHHCCCCCCEEEC
GSITFDGKDLNDLSISERAAAGIFLSLQYPIEIPGVSNVQFLKTALNSIRKQNGEDEIDA
CEEEECCCCCCCCCHHHHHHCEEEEEEECCEECCCCCCHHHHHHHHHHHHHCCCCCHHHH
ISFMKKLKENMQVLKIDQKYMSRGVNEGFSGGEKKRNEMLQLMMLEPKLAILDETDSGLD
HHHHHHHHHCHHEEEECHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCC
IDALQVVSQGANSMRSADRSFLVITHYQRLLDHIQPDFVHVLADGKIVKIGGKELALELE
HHHHHHHHHCHHHHHHCCCCEEEHHHHHHHHHHCCCCEEEEEECCEEEEECCCEEEEEEH
EKGYSWLNS
HCCCCCCCC
>Mature Secondary Structure
MLLEIKDLHVSVGEQKKQILKGLNLTVKKGEVHAIMGPNGAGKSTLSNVLAGKDGYEITQ
CEEEEEHHHCCCCHHHHHHHHCCCEEEECCCEEEEECCCCCCHHHHHHHHCCCCCCEEEC
GSITFDGKDLNDLSISERAAAGIFLSLQYPIEIPGVSNVQFLKTALNSIRKQNGEDEIDA
CEEEECCCCCCCCCHHHHHHCEEEEEEECCEECCCCCCHHHHHHHHHHHHHCCCCCHHHH
ISFMKKLKENMQVLKIDQKYMSRGVNEGFSGGEKKRNEMLQLMMLEPKLAILDETDSGLD
HHHHHHHHHCHHEEEECHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCC
IDALQVVSQGANSMRSADRSFLVITHYQRLLDHIQPDFVHVLADGKIVKIGGKELALELE
HHHHHHHHHCHHHHHHCCCCEEEHHHHHHHHHHCCCCEEEEEECCEEEEECCCEEEEEEH
EKGYSWLNS
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]