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The map label for this gene is fabF [H]

Identifier: 89256461

GI number: 89256461

Start: 1079634

End: 1080893

Strand: Reverse

Name: fabF [H]

Synonym: FTL_1137

Alternate gene names: 89256461

Gene position: 1080893-1079634 (Counterclockwise)

Preceding gene: 89256462

Following gene: 89256460

Centisome position: 57.01

GC content: 38.25

Gene sequence:

>1260_bases
ATGAAATCTAATCGTAGAGTAGTTGTTACTGGCTTAGGCATGGTAACACCTTTAGGAAATGATGTCCCTACGACTTGGGC
TAATATCTTAGCTGGCAAAAGTGGAGTAGAAACTATAACTGGTTTTGACACACCTGCTCCTGATATTAGCGAGTTTAAAG
TTAGATTTGCAGCAAGAATTAAAAATTTTGATGTAGATGCACTTGTAGGTAAAAAAGACGCAAAGAGAGTAGATCCTTTC
TGCTACTATGGTATTGCCGCTGCTAATGAAGCTCTTAAAGATGCTGGAATTGATAAAGTATCTGAAGAAGATTCATATAA
GTTTGGCGTATGTGTTAGTTCTGGTATCGGTGGTATCGAGACTTTAGAAACTACTAAAGCTGTAATAGATACAAAAGGAC
CTTCTAAAATTTCACCTTTTTGTATACCATCCTCAATCGTGAATATGCTCTCTGGAATCATTTCTATAAATCATGGCTTA
CGTGGGCCTAATATTCCAATCGTTACTGCTTGTACTACAGGTACTCATAATATTGGTATGGCTGCTAGATTAATAGCTAG
TGGTGATGCTGATGCTATGCTTGCTGGTGGCTCTGAAAAAGCAAGTAACGCTATTGGTATGGGTGGATTTGCTGCTGCTA
GAGCATTATCAACGCGCAATGATGATCCACAAGGTGCATCACGCCCTTGGGACAAAGACAGAGATGGCTTTGTACTTGGC
GATGGTGCTGGTGTTGTTGTCTTAGAAGAATATGAAAGAGCTAAAGCTCGTGGCGCTAAGATTTATGCTGAGGTTGTGGG
TTTTGGTATGTCTGCTGATGGTTATCATATGACTATGCCTTATGCTCCAGGTCAAGAAAGATGTATTCAGAATGCTTTAG
CTGATGCTGGACTTGAAAATAATCCTGATGCTATAGACTACGTTAATGCTCACGGTACTTCAACTCCACTAGGAGATGTT
CAGGAGTCACAAGTTGTTGAAAAAGTAATTGGACAATATAGAAAAGATCTAGTTATGAGCTCAACAAAATCAATGACAGG
ACATTTACTTGGTGCAGCTGGTGCTATTGAATCAATATTTAGTGTATTAGCAATAAGAGACCAAGTAGCTCCACCAACAA
TAAACCTACATAATTTAGATGATGGCTGTAACTTAGATTATGCTGCAAATGCTGCTAAGAAAATGAAAATTGATTATGTG
CTAAATAACTCTTTTGGTTTTGGTGGCACTAATGGTTCTGTAATTTTCAAAAAAATCTAA

Upstream 100 bases:

>100_bases
GAATCTAAAGATGTAGGTTAATCAAAATTGATCTTAAAGTCAGTATGAATAAGATTTCATACTTTTTTCTACAATGAATA
TAAACAGGTTAATTTAAATT

Downstream 100 bases:

>100_bases
GTATTAATAGCTGATTTCTTATATTTAACCAGTTCGATAAGCTACTTTCTGTGGCTTTTTTTATATACCAAGGAGAAAAT
ATGCAAATTCATATAATTGA

Product: 3-oxoacyl-[acyl-carrier-protein] synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MKSNRRVVVTGLGMVTPLGNDVPTTWANILAGKSGVETITGFDTPAPDISEFKVRFAARIKNFDVDALVGKKDAKRVDPF
CYYGIAAANEALKDAGIDKVSEEDSYKFGVCVSSGIGGIETLETTKAVIDTKGPSKISPFCIPSSIVNMLSGIISINHGL
RGPNIPIVTACTTGTHNIGMAARLIASGDADAMLAGGSEKASNAIGMGGFAAARALSTRNDDPQGASRPWDKDRDGFVLG
DGAGVVVLEEYERAKARGAKIYAEVVGFGMSADGYHMTMPYAPGQERCIQNALADAGLENNPDAIDYVNAHGTSTPLGDV
QESQVVEKVIGQYRKDLVMSSTKSMTGHLLGAAGAIESIFSVLAIRDQVAPPTINLHNLDDGCNLDYAANAAKKMKIDYV
LNNSFGFGGTNGSVIFKKI

Sequences:

>Translated_419_residues
MKSNRRVVVTGLGMVTPLGNDVPTTWANILAGKSGVETITGFDTPAPDISEFKVRFAARIKNFDVDALVGKKDAKRVDPF
CYYGIAAANEALKDAGIDKVSEEDSYKFGVCVSSGIGGIETLETTKAVIDTKGPSKISPFCIPSSIVNMLSGIISINHGL
RGPNIPIVTACTTGTHNIGMAARLIASGDADAMLAGGSEKASNAIGMGGFAAARALSTRNDDPQGASRPWDKDRDGFVLG
DGAGVVVLEEYERAKARGAKIYAEVVGFGMSADGYHMTMPYAPGQERCIQNALADAGLENNPDAIDYVNAHGTSTPLGDV
QESQVVEKVIGQYRKDLVMSSTKSMTGHLLGAAGAIESIFSVLAIRDQVAPPTINLHNLDDGCNLDYAANAAKKMKIDYV
LNNSFGFGGTNGSVIFKKI
>Mature_419_residues
MKSNRRVVVTGLGMVTPLGNDVPTTWANILAGKSGVETITGFDTPAPDISEFKVRFAARIKNFDVDALVGKKDAKRVDPF
CYYGIAAANEALKDAGIDKVSEEDSYKFGVCVSSGIGGIETLETTKAVIDTKGPSKISPFCIPSSIVNMLSGIISINHGL
RGPNIPIVTACTTGTHNIGMAARLIASGDADAMLAGGSEKASNAIGMGGFAAARALSTRNDDPQGASRPWDKDRDGFVLG
DGAGVVVLEEYERAKARGAKIYAEVVGFGMSADGYHMTMPYAPGQERCIQNALADAGLENNPDAIDYVNAHGTSTPLGDV
QESQVVEKVIGQYRKDLVMSSTKSMTGHLLGAAGAIESIFSVLAIRDQVAPPTINLHNLDDGCNLDYAANAAKKMKIDYV
LNNSFGFGGTNGSVIFKKI

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=420, Percent_Identity=42.8571428571429, Blast_Score=327, Evalue=2e-89,
Organism=Homo sapiens, GI223972627, Length=196, Percent_Identity=36.2244897959184, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI41872631, Length=431, Percent_Identity=25.2900232018561, Blast_Score=108, Evalue=6e-24,
Organism=Escherichia coli, GI1787337, Length=420, Percent_Identity=57.3809523809524, Blast_Score=465, Evalue=1e-132,
Organism=Escherichia coli, GI1788663, Length=421, Percent_Identity=35.1543942992874, Blast_Score=234, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI71983541, Length=424, Percent_Identity=36.0849056603774, Blast_Score=228, Evalue=6e-60,
Organism=Caenorhabditis elegans, GI71983535, Length=269, Percent_Identity=43.8661710037175, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI212642053, Length=360, Percent_Identity=28.6111111111111, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=263, Percent_Identity=26.615969581749, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6320904, Length=453, Percent_Identity=37.5275938189845, Blast_Score=259, Evalue=4e-70,
Organism=Drosophila melanogaster, GI24644341, Length=427, Percent_Identity=43.7939110070258, Blast_Score=323, Evalue=2e-88,
Organism=Drosophila melanogaster, GI24581345, Length=434, Percent_Identity=26.036866359447, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI221330659, Length=376, Percent_Identity=26.8617021276596, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI19920632, Length=370, Percent_Identity=27.2972972972973, Blast_Score=102, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 44021; Mature: 44021

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSNRRVVVTGLGMVTPLGNDVPTTWANILAGKSGVETITGFDTPAPDISEFKVRFAARI
CCCCCEEEEEECCEECCCCCCCCHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHHHH
KNFDVDALVGKKDAKRVDPFCYYGIAAANEALKDAGIDKVSEEDSYKFGVCVSSGIGGIE
CCCCCHHHCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCHH
TLETTKAVIDTKGPSKISPFCIPSSIVNMLSGIISINHGLRGPNIPIVTACTTGTHNIGM
HHHHHHHHHCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCH
AARLIASGDADAMLAGGSEKASNAIGMGGFAAARALSTRNDDPQGASRPWDKDRDGFVLG
HHHEEECCCCCEEEECCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEE
DGAGVVVLEEYERAKARGAKIYAEVVGFGMSADGYHMTMPYAPGQERCIQNALADAGLEN
CCCCEEEEECHHHHHHCCHHEEEHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCC
NPDAIDYVNAHGTSTPLGDVQESQVVEKVIGQYRKDLVMSSTKSMTGHLLGAAGAIESIF
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVLAIRDQVAPPTINLHNLDDGCNLDYAANAAKKMKIDYVLNNSFGFGGTNGSVIFKKI
HHHHHHHCCCCCEEEEECCCCCCCCCHHCCCCCEEEEEEEEECCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MKSNRRVVVTGLGMVTPLGNDVPTTWANILAGKSGVETITGFDTPAPDISEFKVRFAARI
CCCCCEEEEEECCEECCCCCCCCHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHHHH
KNFDVDALVGKKDAKRVDPFCYYGIAAANEALKDAGIDKVSEEDSYKFGVCVSSGIGGIE
CCCCCHHHCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCHH
TLETTKAVIDTKGPSKISPFCIPSSIVNMLSGIISINHGLRGPNIPIVTACTTGTHNIGM
HHHHHHHHHCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCH
AARLIASGDADAMLAGGSEKASNAIGMGGFAAARALSTRNDDPQGASRPWDKDRDGFVLG
HHHEEECCCCCEEEECCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEE
DGAGVVVLEEYERAKARGAKIYAEVVGFGMSADGYHMTMPYAPGQERCIQNALADAGLEN
CCCCEEEEECHHHHHHCCHHEEEHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCC
NPDAIDYVNAHGTSTPLGDVQESQVVEKVIGQYRKDLVMSSTKSMTGHLLGAAGAIESIF
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVLAIRDQVAPPTINLHNLDDGCNLDYAANAAKKMKIDYVLNNSFGFGGTNGSVIFKKI
HHHHHHHCCCCCEEEEECCCCCCCCCHHCCCCCEEEEEEEEECCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]