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The map label for this gene is lipB [H]

Identifier: 89256393

GI number: 89256393

Start: 1012669

End: 1013289

Strand: Reverse

Name: lipB [H]

Synonym: FTL_1058

Alternate gene names: 89256393

Gene position: 1013289-1012669 (Counterclockwise)

Preceding gene: 89256394

Following gene: 89256392

Centisome position: 53.44

GC content: 32.85

Gene sequence:

>621_bases
ATGAATAATATTTACCAAAAAGACTTGGGTTTACAACAATATACCAAAGTGTTTGAGGATATGCTTGAGTTTACTTCAAC
ACGAACTCCTGAAACTAACGATGAAATATGGCTAGTTGAACACCCTGCTGTTTTTACTCAAGGTAAACATGGTAAGCCAG
AACATATTCTAAATTCGCATAATATCCCAATAGTTGCAACTGATCGTGGTGGTCAGGTTACTTATCATGGTCCAGGTCAA
GCAGTGATATATTTTCTTCTTGATATTAAGAGAAATAAGCTTGGTGCCAAAAAGTTAGTAACAACTGTTGAGCAAGCTTG
TATCAATATGCTTGATAAATATTATAATCTAAAGGCTCATATTATTGATGGAGCTCATGGTATATATATAAACAATCAAA
AAATTGCCTCTTTAGGCTTAAGAATCAAACAAGGTAAAAGCTATCACGGTATTGCTATAAATACTAATATGGATCTTACA
CCATTTAGCTACATTAATCCCTGTGGTTATAGTGGTTTAAAAATGTGTCAATTAGCTAATTTCTATCAAGAAGCTGATAT
TAAGAAAGTTCAGCAGCAATATACTGCTGAGTTTGTAACTTTGCTAAATAACTCTATCTGA

Upstream 100 bases:

>100_bases
AACTGCGATTTTTACCGCAGATAGTAAAGAACAGCTAGATAATATCTACAAAGAAATTTCAGCACATCCAGAAGTTCACA
TGGTTTTATAAAATTTTGTT

Downstream 100 bases:

>100_bases
GGATTATAGTTCTTATTAATTAATCTCATCTTCAATTTCAGTTTGTTGACTTGCGATGATATTCTTGGCAATAGTAACTC
CTTGCATCTTACATCCAAGG

Product: lipoate-protein ligase B

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MNNIYQKDLGLQQYTKVFEDMLEFTSTRTPETNDEIWLVEHPAVFTQGKHGKPEHILNSHNIPIVATDRGGQVTYHGPGQ
AVIYFLLDIKRNKLGAKKLVTTVEQACINMLDKYYNLKAHIIDGAHGIYINNQKIASLGLRIKQGKSYHGIAINTNMDLT
PFSYINPCGYSGLKMCQLANFYQEADIKKVQQQYTAEFVTLLNNSI

Sequences:

>Translated_206_residues
MNNIYQKDLGLQQYTKVFEDMLEFTSTRTPETNDEIWLVEHPAVFTQGKHGKPEHILNSHNIPIVATDRGGQVTYHGPGQ
AVIYFLLDIKRNKLGAKKLVTTVEQACINMLDKYYNLKAHIIDGAHGIYINNQKIASLGLRIKQGKSYHGIAINTNMDLT
PFSYINPCGYSGLKMCQLANFYQEADIKKVQQQYTAEFVTLLNNSI
>Mature_206_residues
MNNIYQKDLGLQQYTKVFEDMLEFTSTRTPETNDEIWLVEHPAVFTQGKHGKPEHILNSHNIPIVATDRGGQVTYHGPGQ
AVIYFLLDIKRNKLGAKKLVTTVEQACINMLDKYYNLKAHIIDGAHGIYINNQKIASLGLRIKQGKSYHGIAINTNMDLT
PFSYINPCGYSGLKMCQLANFYQEADIKKVQQQYTAEFVTLLNNSI

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG0321

COG function: function code H; Lipoate-protein ligase B

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipB family [H]

Homologues:

Organism=Homo sapiens, GI221554520, Length=169, Percent_Identity=28.9940828402367, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI87081767, Length=203, Percent_Identity=50.2463054187192, Blast_Score=216, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6323268, Length=155, Percent_Identity=38.0645161290323, Blast_Score=88, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21355483, Length=155, Percent_Identity=29.6774193548387, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB [H]

EC number: =2.3.1.181 [H]

Molecular weight: Translated: 23340; Mature: 23340

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS01313 LIPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIYQKDLGLQQYTKVFEDMLEFTSTRTPETNDEIWLVEHPAVFTQGKHGKPEHILNSH
CCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEECCCCCCCHHHHCCC
NIPIVATDRGGQVTYHGPGQAVIYFLLDIKRNKLGAKKLVTTVEQACINMLDKYYNLKAH
CCCEEEECCCCEEEEECCCCEEEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEE
IIDGAHGIYINNQKIASLGLRIKQGKSYHGIAINTNMDLTPFSYINPCGYSGLKMCQLAN
EEECCCEEEECCCEEEECCEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
FYQEADIKKVQQQYTAEFVTLLNNSI
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNNIYQKDLGLQQYTKVFEDMLEFTSTRTPETNDEIWLVEHPAVFTQGKHGKPEHILNSH
CCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEECCCCCCCHHHHCCC
NIPIVATDRGGQVTYHGPGQAVIYFLLDIKRNKLGAKKLVTTVEQACINMLDKYYNLKAH
CCCEEEECCCCEEEEECCCCEEEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEE
IIDGAHGIYINNQKIASLGLRIKQGKSYHGIAINTNMDLTPFSYINPCGYSGLKMCQLAN
EEECCCEEEECCCEEEECCEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
FYQEADIKKVQQQYTAEFVTLLNNSI
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA