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The map label for this gene is dinB [H]

Identifier: 89256328

GI number: 89256328

Start: 951043

End: 952092

Strand: Reverse

Name: dinB [H]

Synonym: FTL_0981

Alternate gene names: 89256328

Gene position: 952092-951043 (Counterclockwise)

Preceding gene: 89256329

Following gene: 89256316

Centisome position: 50.22

GC content: 33.33

Gene sequence:

>1050_bases
ATGACTAAATTAAGAAAAATTATACATATTGATATGGATTATTTCTTCGCTCAAGTAGAAGAAAAAGCAAATCCAAGTCT
AAAAGATAAACCTTTTGCTGTAGGTGGCACCAATCCTAAACGAGGAGTAATATCGACGTGTAATTATATTGCAAGAGAAT
ATGGTGTACGCTCTGCTATGCCTACAGCGATCGCTATGCAGAAATGCCCTAATCTAATACTTTTGAATACTGATTTTGCA
AAATACAAAGCCGCTTCTGCTGTTATTAGAGATATATTTTACTCTTTTACAGATAAGGTTGAGCCTCTATCTCTTGATGA
GGCGTATCTAGATGTCACAGATGTTAAAGAGTATAAAAATAGTGCAACTCTAATTGCTCAAGCTATCAAACAAGAGATTT
TCAACAAAACTGGGCTTACTGGATCAGCTGGAGTAGCTCCAAATAAACTACTTGCAAAGATAGCTAGCGATATAAATAAG
CCTAATGGATTATATGTAGTCACTCCTAAGCAAGTTGATAGTTTTGTAAAAGATTTACCTGTTAAGAAGCTTTTTGGGGT
TGGTAAAGTATCACAAGAAAAACTAAAAAGTATGGGTGTCGAGACTTGCTTAGATTTGCAGCAACTAAGCTTAGCTACTC
TTGTAGATAAGTTTGGTAAATTTGGTAGTAGTTTATATAACTATGCTAGAGGTATTGATAATCGTGAAGTTAACCCTGTA
CGGATTCGTAAATCTGTAAGTGTTGAAAATACATATTTAGAAGATCTAAAGACTCTCGGAGCTTGCCTAGAAAAACTACC
AAGCTTATATGATAAATTGACCAGTCGCATGACTGAAGAGCATTATAAATCTATAATTGGCATTGTTGTCAAATTTACAG
ATACAAAATTTAATAAAACCAGTCTAACTAGAGTAGCAAAAATACTAGATAAAGAAATGCTAAAAAATCTAATAATTGAG
TTACATCAAAAACGAAATCACCCTATTCGACTAATTGGTATAGGTGTAAAACTTGGGGAGATTGATGATAAACAGATGGA
TTTATTCTAA

Upstream 100 bases:

>100_bases
AGGCTATCAAGTAGCTAAACAGAAAAGTATCGAGATAGAATACTCATGGCAAGAAGATCCAAATATTGATGAGTTTGCTG
ATTTTTATAAATAAGACTTT

Downstream 100 bases:

>100_bases
AACTTTTAAGATTTAGATATCATATTTTCTCATGTAGATCTTTTAAGTCTCTTCCTTTTTCATACTTCCAAAAGGTTAAA
CCGTTTCTAGTGCTTGTTTT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MTKLRKIIHIDMDYFFAQVEEKANPSLKDKPFAVGGTNPKRGVISTCNYIAREYGVRSAMPTAIAMQKCPNLILLNTDFA
KYKAASAVIRDIFYSFTDKVEPLSLDEAYLDVTDVKEYKNSATLIAQAIKQEIFNKTGLTGSAGVAPNKLLAKIASDINK
PNGLYVVTPKQVDSFVKDLPVKKLFGVGKVSQEKLKSMGVETCLDLQQLSLATLVDKFGKFGSSLYNYARGIDNREVNPV
RIRKSVSVENTYLEDLKTLGACLEKLPSLYDKLTSRMTEEHYKSIIGIVVKFTDTKFNKTSLTRVAKILDKEMLKNLIIE
LHQKRNHPIRLIGIGVKLGEIDDKQMDLF

Sequences:

>Translated_349_residues
MTKLRKIIHIDMDYFFAQVEEKANPSLKDKPFAVGGTNPKRGVISTCNYIAREYGVRSAMPTAIAMQKCPNLILLNTDFA
KYKAASAVIRDIFYSFTDKVEPLSLDEAYLDVTDVKEYKNSATLIAQAIKQEIFNKTGLTGSAGVAPNKLLAKIASDINK
PNGLYVVTPKQVDSFVKDLPVKKLFGVGKVSQEKLKSMGVETCLDLQQLSLATLVDKFGKFGSSLYNYARGIDNREVNPV
RIRKSVSVENTYLEDLKTLGACLEKLPSLYDKLTSRMTEEHYKSIIGIVVKFTDTKFNKTSLTRVAKILDKEMLKNLIIE
LHQKRNHPIRLIGIGVKLGEIDDKQMDLF
>Mature_348_residues
TKLRKIIHIDMDYFFAQVEEKANPSLKDKPFAVGGTNPKRGVISTCNYIAREYGVRSAMPTAIAMQKCPNLILLNTDFAK
YKAASAVIRDIFYSFTDKVEPLSLDEAYLDVTDVKEYKNSATLIAQAIKQEIFNKTGLTGSAGVAPNKLLAKIASDINKP
NGLYVVTPKQVDSFVKDLPVKKLFGVGKVSQEKLKSMGVETCLDLQQLSLATLVDKFGKFGSSLYNYARGIDNREVNPVR
IRKSVSVENTYLEDLKTLGACLEKLPSLYDKLTSRMTEEHYKSIIGIVVKFTDTKFNKTSLTRVAKILDKEMLKNLIIEL
HQKRNHPIRLIGIGVKLGEIDDKQMDLF

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=299, Percent_Identity=33.7792642140468, Blast_Score=164, Evalue=9e-41,
Organism=Homo sapiens, GI7706681, Length=300, Percent_Identity=33.6666666666667, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI154350220, Length=285, Percent_Identity=31.5789473684211, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI7705344, Length=248, Percent_Identity=32.6612903225806, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI5729982, Length=319, Percent_Identity=26.3322884012539, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1786425, Length=349, Percent_Identity=49.5702005730659, Blast_Score=325, Evalue=3e-90,
Organism=Escherichia coli, GI1787432, Length=205, Percent_Identity=26.8292682926829, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI193205700, Length=400, Percent_Identity=31.5, Blast_Score=147, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI17537959, Length=263, Percent_Identity=31.9391634980989, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI193205702, Length=345, Percent_Identity=29.2753623188406, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI115534089, Length=346, Percent_Identity=25.1445086705202, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324921, Length=213, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19923006, Length=407, Percent_Identity=27.5184275184275, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21355641, Length=284, Percent_Identity=32.3943661971831, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24644984, Length=284, Percent_Identity=32.3943661971831, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24668444, Length=123, Percent_Identity=37.3983739837398, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39085; Mature: 38954

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLRKIIHIDMDYFFAQVEEKANPSLKDKPFAVGGTNPKRGVISTCNYIAREYGVRSAM
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHCCHHCC
PTAIAMQKCPNLILLNTDFAKYKAASAVIRDIFYSFTDKVEPLSLDEAYLDVTDVKEYKN
HHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
SATLIAQAIKQEIFNKTGLTGSAGVAPNKLLAKIASDINKPNGLYVVTPKQVDSFVKDLP
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHCC
VKKLFGVGKVSQEKLKSMGVETCLDLQQLSLATLVDKFGKFGSSLYNYARGIDNREVNPV
HHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
RIRKSVSVENTYLEDLKTLGACLEKLPSLYDKLTSRMTEEHYKSIIGIVVKFTDTKFNKT
EEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHH
SLTRVAKILDKEMLKNLIIELHQKRNHPIRLIGIGVKLGEIDDKQMDLF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
TKLRKIIHIDMDYFFAQVEEKANPSLKDKPFAVGGTNPKRGVISTCNYIAREYGVRSAM
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHCCHHCC
PTAIAMQKCPNLILLNTDFAKYKAASAVIRDIFYSFTDKVEPLSLDEAYLDVTDVKEYKN
HHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
SATLIAQAIKQEIFNKTGLTGSAGVAPNKLLAKIASDINKPNGLYVVTPKQVDSFVKDLP
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHCC
VKKLFGVGKVSQEKLKSMGVETCLDLQQLSLATLVDKFGKFGSSLYNYARGIDNREVNPV
HHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
RIRKSVSVENTYLEDLKTLGACLEKLPSLYDKLTSRMTEEHYKSIIGIVVKFTDTKFNKT
EEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHH
SLTRVAKILDKEMLKNLIIELHQKRNHPIRLIGIGVKLGEIDDKQMDLF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA