Click here to switch to the map view.

The map label for this gene is ruvA

Identifier: 89256283

GI number: 89256283

Start: 904162

End: 904812

Strand: Direct

Name: ruvA

Synonym: FTL_0932

Alternate gene names: 89256283

Gene position: 904162-904812 (Clockwise)

Preceding gene: 89256282

Following gene: 89256284

Centisome position: 47.69

GC content: 33.33

Gene sequence:

>651_bases
ATGATAAGTTTTATAAAAGGTGTATTGATAGAGAAAGATCCAACAGCTTTGCTTATTGATGTAAATGGTATTGGTTATGA
AGTTTTTGTACCGATGACAACATTTTATACATTAGGTGATATTGATAGTCAGGTTAGCCTTTATACACATTTTGTAGTTC
GTGAAGATGCTCAGCAACTCTATGGGTTTAAATCAAAAGTTGATAAGAAAGTTTTCCAAGAGTTAATTAAAGTCAATGGT
ATAGGAGCTAGAACAGCTATTGCTATTTTATCTGGTATGGATTCAAAAACTCTATTACATTGTATTGAAAATAAAGATTA
TGCTTTATTAGCTACAGTGCCAGGAATTGGTAAAAAAACTGCTGAGCGTTTAGTTGTAGAAATTTATGATAAGTTATTAA
AAATGGCTAATGAGATTTATGCTCAGACTTCAGGTACAACTACAACTAGTCAAGATTCACAAGCACAACAGGCACCAACA
TCTGTAGTATTAGCAAACTCAATATTTAACGAATCCGTTGATGCATTATTGGCATTAGGCTATAAGCAAAAAGATGCTGA
AAAAATGGCTCGCTCTGCTATGGGTGATGCAACTACAGCAGCAGAGGTAATTCGTAAAGCTCTGCAAGGATCAATAAAAT
CAAAAGGATAA

Upstream 100 bases:

>100_bases
TATTTTGTTAGCTCTGTCAATTCTTCCTATCGCTTTTTTAGCAGCACTTATAGTAAGCTTAAAATTATCAACAGTTCAAA
GGGACTAAGGGATATTATTG

Downstream 100 bases:

>100_bases
TAATTATAATATAAGGGGAAGACAAATGATACTAGCTATAGCATTAATAATGCTATTAATTATTTTTGGCATAATATTTT
TTTTAATAATTAACAAAAAA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MISFIKGVLIEKDPTALLIDVNGIGYEVFVPMTTFYTLGDIDSQVSLYTHFVVREDAQQLYGFKSKVDKKVFQELIKVNG
IGARTAIAILSGMDSKTLLHCIENKDYALLATVPGIGKKTAERLVVEIYDKLLKMANEIYAQTSGTTTTSQDSQAQQAPT
SVVLANSIFNESVDALLALGYKQKDAEKMARSAMGDATTAAEVIRKALQGSIKSKG

Sequences:

>Translated_216_residues
MISFIKGVLIEKDPTALLIDVNGIGYEVFVPMTTFYTLGDIDSQVSLYTHFVVREDAQQLYGFKSKVDKKVFQELIKVNG
IGARTAIAILSGMDSKTLLHCIENKDYALLATVPGIGKKTAERLVVEIYDKLLKMANEIYAQTSGTTTTSQDSQAQQAPT
SVVLANSIFNESVDALLALGYKQKDAEKMARSAMGDATTAAEVIRKALQGSIKSKG
>Mature_216_residues
MISFIKGVLIEKDPTALLIDVNGIGYEVFVPMTTFYTLGDIDSQVSLYTHFVVREDAQQLYGFKSKVDKKVFQELIKVNG
IGARTAIAILSGMDSKTLLHCIENKDYALLATVPGIGKKTAERLVVEIYDKLLKMANEIYAQTSGTTTTSQDSQAQQAPT
SVVLANSIFNESVDALLALGYKQKDAEKMARSAMGDATTAAEVIRKALQGSIKSKG

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=213, Percent_Identity=41.7840375586854, Blast_Score=177, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_FRATF (A7NBV5)

Other databases:

- EMBL:   CP000803
- RefSeq:   YP_001428414.1
- ProteinModelPortal:   A7NBV5
- SMR:   A7NBV5
- STRING:   A7NBV5
- GeneID:   5523558
- GenomeReviews:   CP000803_GR
- KEGG:   fta:FTA_0982
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   LFGFAQK
- ProtClustDB:   PRK00116
- BioCyc:   FTUL458234:FTA_0982-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 23450; Mature: 23450

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISFIKGVLIEKDPTALLIDVNGIGYEVFVPMTTFYTLGDIDSQVSLYTHFVVREDAQQL
CCCHHCCEEECCCCCEEEEEECCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
YGFKSKVDKKVFQELIKVNGIGARTAIAILSGMDSKTLLHCIENKDYALLATVPGIGKKT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCHHH
AERLVVEIYDKLLKMANEIYAQTSGTTTTSQDSQAQQAPTSVVLANSIFNESVDALLALG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHC
YKQKDAEKMARSAMGDATTAAEVIRKALQGSIKSKG
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MISFIKGVLIEKDPTALLIDVNGIGYEVFVPMTTFYTLGDIDSQVSLYTHFVVREDAQQL
CCCHHCCEEECCCCCEEEEEECCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
YGFKSKVDKKVFQELIKVNGIGARTAIAILSGMDSKTLLHCIENKDYALLATVPGIGKKT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCHHH
AERLVVEIYDKLLKMANEIYAQTSGTTTTSQDSQAQQAPTSVVLANSIFNESVDALLALG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHC
YKQKDAEKMARSAMGDATTAAEVIRKALQGSIKSKG
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA