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The map label for this gene is aroA [H]

Identifier: 89256212

GI number: 89256212

Start: 833528

End: 834805

Strand: Direct

Name: aroA [H]

Synonym: FTL_0852

Alternate gene names: 89256212

Gene position: 833528-834805 (Clockwise)

Preceding gene: 89256211

Following gene: 89256213

Centisome position: 43.96

GC content: 36.54

Gene sequence:

>1278_bases
ATGAAAGATTTTATCCCTCAAATAAAATCACAGATAAAACAGCAAGTGTATTTAGATGGCTCAAAGAGTATCTCAAATAG
ATCACTGATAATCGCAGCGATGGCTCAAGGTCAAACAAAATTTGAGAATTTGCCTAATAGTGCTGATGTTTTAGCATGTA
TTGCAGCTCTAAAGGAGTTAGGTTGTCAGCTAGAACATAGCTGGGATTCAAAAACTTTAGTTATTCAAGGTTGTAGTGGA
GTATTTGCGAACTTAGATGCCAAGATATTTTGTAATGAGTCTGGTACTTTAACAAGATTTATAATACCAATGTTAGCAGT
GCAGTCTACAGGTAAATATTACGTATATGCCAAGCAAAGAATGATGGATAGACCCTTAGCAGATCAACTAAAACCGCTTG
AAAAGTTAGGTATGCTAGCAAATTACCATCAAAAGGCTTATGCTATGCCTTTGACAATAATAGCTAAATCTTTGGATGGT
GGTTATATAGAAGTTGATGGCGAGAAGAGTTCGCAATTTGCCTCAGGTTTGCTGATGGCAGCACCATTTATGCATTGTGG
CTTAAGATTAAATTCTATCACAGACCACAAGCAACCGTACTTAGATATGACAACTAAAGTTATGGCAGAGTTTGGTGTGA
CAGTAGATATTGATGAAAATATCTATACTGCCAACAAATCTCAATATATCTCTACTAGTAATTATGTAGTTGAACCAGAT
GTTTCGACAGCTTCATATTTTTGGGCATTTGCAGCTATCACCGGTTCAACTATCAAGGTTATGCATGTTACTAAAAACTC
TAAGCAAGGTGATATTAAATTTTTAGAAGTACTTGAGAAAATAGGCTGTCAAGTTAATTACTACAATGATGGTATAGAGG
TTACAGGTAATAATCAGCTTCGTGGTATACAAGTTAATATGCGTAACTTCTCTGATACTTTCATGACGCTTGCAGCTATT
GCTTGCTTTGCTAAAGGCGATACGCATATTTCAGGTCTTAGTCATACACGTGGTCAAGAATCAGATCGCATTGCAGCTAT
GGCAGAGGGACTTAGCAAGCTTGGTATCTATGTGGAGACTACTCAAGATAGTATTTTAATCTCGCCAGCTAGAAGTAAAT
TTAAGCCAGCTGAAGTTGATAGTCATAATGATCACCGTATCGCTATGTCTTTAGCACTTTTAGGCTTAAAATATCAAGGT
GTAATAGTAAATAATGCAGCGGCTGTAAGCAAAACTTGCCCAGATTATTTTGATAGAATGAGAGCATTGGTAGGTTAG

Upstream 100 bases:

>100_bases
TCGCTCTTAATATTTTGTCTATTTAGATAATTAATTATTCAAAAAAATACTAGTAGTTATGTTAATATAAACATCAATGT
AATTTTTTTAAATTAAACAA

Downstream 100 bases:

>100_bases
CTATGATAAAAAAAGAGCGTATTATAACCAGATATCTAAGTCAAAGGTGGTATAAAAAAGCTCTTATCATCACAGCTACA
GAGAGTAATTATTTTCATAA

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MKDFIPQIKSQIKQQVYLDGSKSISNRSLIIAAMAQGQTKFENLPNSADVLACIAALKELGCQLEHSWDSKTLVIQGCSG
VFANLDAKIFCNESGTLTRFIIPMLAVQSTGKYYVYAKQRMMDRPLADQLKPLEKLGMLANYHQKAYAMPLTIIAKSLDG
GYIEVDGEKSSQFASGLLMAAPFMHCGLRLNSITDHKQPYLDMTTKVMAEFGVTVDIDENIYTANKSQYISTSNYVVEPD
VSTASYFWAFAAITGSTIKVMHVTKNSKQGDIKFLEVLEKIGCQVNYYNDGIEVTGNNQLRGIQVNMRNFSDTFMTLAAI
ACFAKGDTHISGLSHTRGQESDRIAAMAEGLSKLGIYVETTQDSILISPARSKFKPAEVDSHNDHRIAMSLALLGLKYQG
VIVNNAAAVSKTCPDYFDRMRALVG

Sequences:

>Translated_425_residues
MKDFIPQIKSQIKQQVYLDGSKSISNRSLIIAAMAQGQTKFENLPNSADVLACIAALKELGCQLEHSWDSKTLVIQGCSG
VFANLDAKIFCNESGTLTRFIIPMLAVQSTGKYYVYAKQRMMDRPLADQLKPLEKLGMLANYHQKAYAMPLTIIAKSLDG
GYIEVDGEKSSQFASGLLMAAPFMHCGLRLNSITDHKQPYLDMTTKVMAEFGVTVDIDENIYTANKSQYISTSNYVVEPD
VSTASYFWAFAAITGSTIKVMHVTKNSKQGDIKFLEVLEKIGCQVNYYNDGIEVTGNNQLRGIQVNMRNFSDTFMTLAAI
ACFAKGDTHISGLSHTRGQESDRIAAMAEGLSKLGIYVETTQDSILISPARSKFKPAEVDSHNDHRIAMSLALLGLKYQG
VIVNNAAAVSKTCPDYFDRMRALVG
>Mature_425_residues
MKDFIPQIKSQIKQQVYLDGSKSISNRSLIIAAMAQGQTKFENLPNSADVLACIAALKELGCQLEHSWDSKTLVIQGCSG
VFANLDAKIFCNESGTLTRFIIPMLAVQSTGKYYVYAKQRMMDRPLADQLKPLEKLGMLANYHQKAYAMPLTIIAKSLDG
GYIEVDGEKSSQFASGLLMAAPFMHCGLRLNSITDHKQPYLDMTTKVMAEFGVTVDIDENIYTANKSQYISTSNYVVEPD
VSTASYFWAFAAITGSTIKVMHVTKNSKQGDIKFLEVLEKIGCQVNYYNDGIEVTGNNQLRGIQVNMRNFSDTFMTLAAI
ACFAKGDTHISGLSHTRGQESDRIAAMAEGLSKLGIYVETTQDSILISPARSKFKPAEVDSHNDHRIAMSLALLGLKYQG
VIVNNAAAVSKTCPDYFDRMRALVG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=424, Percent_Identity=35.377358490566, Blast_Score=218, Evalue=5e-58,
Organism=Saccharomyces cerevisiae, GI6320332, Length=461, Percent_Identity=31.0195227765727, Blast_Score=186, Evalue=8e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46781; Mature: 46781

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDFIPQIKSQIKQQVYLDGSKSISNRSLIIAAMAQGQTKFENLPNSADVLACIAALKEL
CCCHHHHHHHHHHHHEECCCCCCCCCCEEEEEEECCCCHHHHCCCCHHHHHHHHHHHHHH
GCQLEHSWDSKTLVIQGCSGVFANLDAKIFCNESGTLTRFIIPMLAVQSTGKYYVYAKQR
CCEEECCCCCCEEEEEECCCHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEHHH
MMDRPLADQLKPLEKLGMLANYHQKAYAMPLTIIAKSLDGGYIEVDGEKSSQFASGLLMA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHEECCCCCEEEECCCCCHHHHHHHHHH
APFMHCGLRLNSITDHKQPYLDMTTKVMAEFGVTVDIDENIYTANKSQYISTSNYVVEPD
HHHHHCCCEECCCCCCCCCHHHHHHHHHHHCCCEEEECCCEEECCCCCEEECCCEEECCC
VSTASYFWAFAAITGSTIKVMHVTKNSKQGDIKFLEVLEKIGCQVNYYNDGIEVTGNNQL
CCHHHHHHHHEEECCCEEEEEEEECCCCCCCHHHHHHHHHHCCEEEEECCCEEECCCCCE
RGIQVNMRNFSDTFMTLAAIACFAKGDTHISGLSHTRGQESDRIAAMAEGLSKLGIYVET
EEEEEECCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHCCEEEEE
TQDSILISPARSKFKPAEVDSHNDHRIAMSLALLGLKYQGVIVNNAAAVSKTCPDYFDRM
CCCEEEEECCCCCCCCCCCCCCCCCHHHEEHHHHCEEECCEEEECCHHHHHCCHHHHHHH
RALVG
HHHCC
>Mature Secondary Structure
MKDFIPQIKSQIKQQVYLDGSKSISNRSLIIAAMAQGQTKFENLPNSADVLACIAALKEL
CCCHHHHHHHHHHHHEECCCCCCCCCCEEEEEEECCCCHHHHCCCCHHHHHHHHHHHHHH
GCQLEHSWDSKTLVIQGCSGVFANLDAKIFCNESGTLTRFIIPMLAVQSTGKYYVYAKQR
CCEEECCCCCCEEEEEECCCHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEHHH
MMDRPLADQLKPLEKLGMLANYHQKAYAMPLTIIAKSLDGGYIEVDGEKSSQFASGLLMA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHEECCCCCEEEECCCCCHHHHHHHHHH
APFMHCGLRLNSITDHKQPYLDMTTKVMAEFGVTVDIDENIYTANKSQYISTSNYVVEPD
HHHHHCCCEECCCCCCCCCHHHHHHHHHHHCCCEEEECCCEEECCCCCEEECCCEEECCC
VSTASYFWAFAAITGSTIKVMHVTKNSKQGDIKFLEVLEKIGCQVNYYNDGIEVTGNNQL
CCHHHHHHHHEEECCCEEEEEEEECCCCCCCHHHHHHHHHHCCEEEEECCCEEECCCCCE
RGIQVNMRNFSDTFMTLAAIACFAKGDTHISGLSHTRGQESDRIAAMAEGLSKLGIYVET
EEEEEECCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHCCEEEEE
TQDSILISPARSKFKPAEVDSHNDHRIAMSLALLGLKYQGVIVNNAAAVSKTCPDYFDRM
CCCEEEEECCCCCCCCCCCCCCCCCHHHEEHHHHCEEECCEEEECCHHHHHCCHHHHHHH
RALVG
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA