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The map label for this gene is aatA [H]

Identifier: 89256162

GI number: 89256162

Start: 774948

End: 776141

Strand: Direct

Name: aatA [H]

Synonym: FTL_0789

Alternate gene names: 89256162

Gene position: 774948-776141 (Clockwise)

Preceding gene: 89256161

Following gene: 89256163

Centisome position: 40.87

GC content: 35.68

Gene sequence:

>1194_bases
ATGGCATCGCTTAACAAAAAGATTCAAAATGTTTCGACTTCACCAACTAATGCTATGGCGGCATTAGCAAAGCAAATCAA
AGATCAAGGAAATGATGTAATCTCTCTTGCTATCGGAGAACCTGGATTTAGTACCCCAGATATTATCAAAGCTGCTGGTA
TCGAAGCAATAAATAAAGATATTACTAAATATACAAATGTCGATGGTCTTAAAGAACTGCGTGAGGCTATAGTAGCTCGT
TACAAGCGTGAATATGGTATTGAGTTTGCTGCAGATCAAGTCTGTGTTACCTCTGGGGCTAAGCATAGTTTGCATAATAT
TTTTAACTGTATTTTAGAAGCAGGTGATGAGGCGATTTTCTTTGCACCGTATTGGGTATCATATCCAGATATGATAGCAC
TTACAGGAGCAAAACCAGTAGTTGTCGAAACTAAGTTTGAGAATAACTTTGAGATAGATGTTACAGACTTAGAAAAACAT
ATTACAGCAAAAACTAAAGCTGTGATTATCAACTCACCTAATAATCCTACCGGTTTGATCTACTCTAAAAAATGTATCGA
AGATTTAGCAAATTTACTTAGAAAGTATCCAAATATTTGGATTATTGGTGATGATATTTATGACCAACTTTACTTTAAGG
ATAGAGTTACATTGATAACTGAAGTAGCACCTGATTTAGCTGATAGATATGTGATCGCTAGTGGTGTGTCAAAAAACTTT
GCGATGACTGGTTGGCGTGTGGGTTTTACAATAGCGCCAAAGCTTTTAAATGATGCACTGAAAAAATTCCAGTCACAATC
TGCTACTTGTGCTTGCTCGATATCACAATATGCTGCAATTACTGCTATGAATATGCCAGCACAAGATTTACAGTATTTTG
TTGAATCTTACAAGCAAAAAGCACAATTCATTACTAAGTATCTAGAAGCTATGCCATATATTGATGTAAAGAGTGCTGAA
GGTACTTTTTATCTTTTTCCAGATCTTAGAAAATTACTTGAGCATACTAATTTTAGTACTGATGTCGAGCTATGTAACGC
ACTACTTAGAGAAGAGTATGTAGCGATGATGCCTGGTGTGGCATTTGGTTTATCAGGTTTTGCTAGGATAAGTTGTGCTA
ATGAAATGCCAGAGCTTGAAGAGGCTATGACTAGAGTAGCCAGATTTATTAATAAGCATGTTTCAACAAAGTAA

Upstream 100 bases:

>100_bases
GCCGTTAGTGGAATCTGATTCGTATAGTTATGTAAATAATTACACTTGCATTGAAATTAGGCAAAATGAATTTAAAGTAG
AAAAGTTATAAGGAACAAAA

Downstream 100 bases:

>100_bases
TACATTCTCGTTGCTTACTATGTAAGCTATAAATTTATTAAATACAAAAAATATTTTCGACACTAAATTAGATAGCTGCT
ACAATCTATAATTATTTCTC

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MASLNKKIQNVSTSPTNAMAALAKQIKDQGNDVISLAIGEPGFSTPDIIKAAGIEAINKDITKYTNVDGLKELREAIVAR
YKREYGIEFAADQVCVTSGAKHSLHNIFNCILEAGDEAIFFAPYWVSYPDMIALTGAKPVVVETKFENNFEIDVTDLEKH
ITAKTKAVIINSPNNPTGLIYSKKCIEDLANLLRKYPNIWIIGDDIYDQLYFKDRVTLITEVAPDLADRYVIASGVSKNF
AMTGWRVGFTIAPKLLNDALKKFQSQSATCACSISQYAAITAMNMPAQDLQYFVESYKQKAQFITKYLEAMPYIDVKSAE
GTFYLFPDLRKLLEHTNFSTDVELCNALLREEYVAMMPGVAFGLSGFARISCANEMPELEEAMTRVARFINKHVSTK

Sequences:

>Translated_397_residues
MASLNKKIQNVSTSPTNAMAALAKQIKDQGNDVISLAIGEPGFSTPDIIKAAGIEAINKDITKYTNVDGLKELREAIVAR
YKREYGIEFAADQVCVTSGAKHSLHNIFNCILEAGDEAIFFAPYWVSYPDMIALTGAKPVVVETKFENNFEIDVTDLEKH
ITAKTKAVIINSPNNPTGLIYSKKCIEDLANLLRKYPNIWIIGDDIYDQLYFKDRVTLITEVAPDLADRYVIASGVSKNF
AMTGWRVGFTIAPKLLNDALKKFQSQSATCACSISQYAAITAMNMPAQDLQYFVESYKQKAQFITKYLEAMPYIDVKSAE
GTFYLFPDLRKLLEHTNFSTDVELCNALLREEYVAMMPGVAFGLSGFARISCANEMPELEEAMTRVARFINKHVSTK
>Mature_396_residues
ASLNKKIQNVSTSPTNAMAALAKQIKDQGNDVISLAIGEPGFSTPDIIKAAGIEAINKDITKYTNVDGLKELREAIVARY
KREYGIEFAADQVCVTSGAKHSLHNIFNCILEAGDEAIFFAPYWVSYPDMIALTGAKPVVVETKFENNFEIDVTDLEKHI
TAKTKAVIINSPNNPTGLIYSKKCIEDLANLLRKYPNIWIIGDDIYDQLYFKDRVTLITEVAPDLADRYVIASGVSKNFA
MTGWRVGFTIAPKLLNDALKKFQSQSATCACSISQYAAITAMNMPAQDLQYFVESYKQKAQFITKYLEAMPYIDVKSAEG
TFYLFPDLRKLLEHTNFSTDVELCNALLREEYVAMMPGVAFGLSGFARISCANEMPELEEAMTRVARFINKHVSTK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=355, Percent_Identity=25.9154929577465, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI56713254, Length=355, Percent_Identity=25.9154929577465, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI95147551, Length=319, Percent_Identity=24.4514106583072, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI169881279, Length=319, Percent_Identity=24.4514106583072, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI4507369, Length=400, Percent_Identity=25.25, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI169881281, Length=203, Percent_Identity=23.6453201970443, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI19263340, Length=355, Percent_Identity=22.2535211267606, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI215599424, Length=355, Percent_Identity=22.2535211267606, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1786816, Length=378, Percent_Identity=26.7195767195767, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1788627, Length=412, Percent_Identity=24.2718446601942, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1788722, Length=367, Percent_Identity=27.2479564032698, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI1787710, Length=337, Percent_Identity=24.9258160237389, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17567663, Length=387, Percent_Identity=26.6149870801034, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17567369, Length=364, Percent_Identity=26.3736263736264, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI71994476, Length=326, Percent_Identity=26.6871165644172, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI71994472, Length=326, Percent_Identity=26.6871165644172, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI71981209, Length=375, Percent_Identity=21.8666666666667, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322401, Length=368, Percent_Identity=30.1630434782609, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28573069, Length=360, Percent_Identity=25.2777777777778, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24646114, Length=360, Percent_Identity=25.2777777777778, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI28573067, Length=360, Percent_Identity=25.2777777777778, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI28573065, Length=360, Percent_Identity=25.2777777777778, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI18859735, Length=387, Percent_Identity=24.031007751938, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44197; Mature: 44066

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLNKKIQNVSTSPTNAMAALAKQIKDQGNDVISLAIGEPGFSTPDIIKAAGIEAINKD
CCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHCHHHHHHH
ITKYTNVDGLKELREAIVARYKREYGIEFAADQVCVTSGAKHSLHNIFNCILEAGDEAIF
HHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCEEE
FAPYWVSYPDMIALTGAKPVVVETKFENNFEIDVTDLEKHITAKTKAVIINSPNNPTGLI
EEEHHCCCCCEEEECCCCCEEEEEECCCCCEEEHHHHHHHHHCCEEEEEEECCCCCCEEE
YSKKCIEDLANLLRKYPNIWIIGDDIYDQLYFKDRVTLITEVAPDLADRYVIASGVSKNF
ECHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCC
AMTGWRVGFTIAPKLLNDALKKFQSQSATCACSISQYAAITAMNMPAQDLQYFVESYKQK
EECCEEECCEECHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHH
AQFITKYLEAMPYIDVKSAEGTFYLFPDLRKLLEHTNFSTDVELCNALLREEYVAMMPGV
HHHHHHHHHHCCCCEEECCCCCEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCH
AFGLSGFARISCANEMPELEEAMTRVARFINKHVSTK
HHHHCCHHEEECHHCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ASLNKKIQNVSTSPTNAMAALAKQIKDQGNDVISLAIGEPGFSTPDIIKAAGIEAINKD
CCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHCHHHHHHH
ITKYTNVDGLKELREAIVARYKREYGIEFAADQVCVTSGAKHSLHNIFNCILEAGDEAIF
HHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCEEE
FAPYWVSYPDMIALTGAKPVVVETKFENNFEIDVTDLEKHITAKTKAVIINSPNNPTGLI
EEEHHCCCCCEEEECCCCCEEEEEECCCCCEEEHHHHHHHHHCCEEEEEEECCCCCCEEE
YSKKCIEDLANLLRKYPNIWIIGDDIYDQLYFKDRVTLITEVAPDLADRYVIASGVSKNF
ECHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCC
AMTGWRVGFTIAPKLLNDALKKFQSQSATCACSISQYAAITAMNMPAQDLQYFVESYKQK
EECCEEECCEECHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHH
AQFITKYLEAMPYIDVKSAEGTFYLFPDLRKLLEHTNFSTDVELCNALLREEYVAMMPGV
HHHHHHHHHHCCCCEEECCCCCEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCH
AFGLSGFARISCANEMPELEEAMTRVARFINKHVSTK
HHHHCCHHEEECHHCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA