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The map label for this gene is murB [H]

Identifier: 89255823

GI number: 89255823

Start: 379923

End: 380771

Strand: Reverse

Name: murB [H]

Synonym: FTL_0412

Alternate gene names: 89255823

Gene position: 380771-379923 (Counterclockwise)

Preceding gene: 89255824

Following gene: 89255822

Centisome position: 20.08

GC content: 30.39

Gene sequence:

>849_bases
ATGTCAGAGTATATATCTTTAGAGCAATATAATACCTATCGTATTAAGTCTTTTGCTAAATATGTTTATTTTCCTACTAA
TAACCAAGAGCTATTGAATATTGTTAATAATCATAATAAATTATTTTTCCTTGGAAACGGTAGCAATGTTATTTTTTCTA
AAGAGTATTATGATGATGTAGCATTTGTGATTTTTACTAAAAAATTCAACTCTTTTAACATTATTGATAATTATGCTAGT
GTCCAAGCTGGAGTATTATTACAGGATCTTGCATTTGCTACCTATAATGCCAGCTTAAGTGGTATTGAGACTTTTTATGA
TGTGCCAGCTAGCGTTGGTGGGGCATTGATTATGAATGCTGGTGCATATGGTGATGAGATATATACTTGTGTCAAAAGTG
TCACAATACTTGACCTTAATACTAAACAGATAAAAAAATATCTAAAAAAAGATATAGAGTATGGTTATAGATACTCTATG
TTTAAATATATGAAAGATATTTGTATTTTATCAGCGGAATTTGAGTTTGAGTACAAATCAAAACAAGAAATCAAAGCAAA
ACTAGATGATATTTATTCACTCAGATTGTCTAATTTACCACAAAAGCCAACAGCTGGGAGTGTTTTCAAGCGACCACAAG
CAAATATGCCTGTGGGAATTATGGTAGAGCAGCTAGGATTAAAAGGTAAACAAATTGGTGATGCGCAAATTTCTCCAAAA
CATGGAGGTATAATAGTGAATAATGGTAATGCAACTGGTCAAAATATTTTAGATCTTATCGAGTTTATCAAACAACAAAT
TTTAGAGCATTATAATATCGAGCTGCATGAAGAGCAAATTGTTATTTAA

Upstream 100 bases:

>100_bases
AATAATGCTCATCAGATATTTAGAGGTTATAATAACCTTATAGAAAATATGTCTCATTTTATGCGAATAGAGATTCTAAA
TGATAATGTTTAGGTGAATA

Downstream 100 bases:

>100_bases
ATTGCTTTAGATAAAACCTCTTTCTTATATGCATAATATCTACTATACTTTGCATAGGGAAAAATTTTTTGTTAAGTTAT
GAAAAAAAAAGTTTTAACTT

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSEYISLEQYNTYRIKSFAKYVYFPTNNQELLNIVNNHNKLFFLGNGSNVIFSKEYYDDVAFVIFTKKFNSFNIIDNYAS
VQAGVLLQDLAFATYNASLSGIETFYDVPASVGGALIMNAGAYGDEIYTCVKSVTILDLNTKQIKKYLKKDIEYGYRYSM
FKYMKDICILSAEFEFEYKSKQEIKAKLDDIYSLRLSNLPQKPTAGSVFKRPQANMPVGIMVEQLGLKGKQIGDAQISPK
HGGIIVNNGNATGQNILDLIEFIKQQILEHYNIELHEEQIVI

Sequences:

>Translated_282_residues
MSEYISLEQYNTYRIKSFAKYVYFPTNNQELLNIVNNHNKLFFLGNGSNVIFSKEYYDDVAFVIFTKKFNSFNIIDNYAS
VQAGVLLQDLAFATYNASLSGIETFYDVPASVGGALIMNAGAYGDEIYTCVKSVTILDLNTKQIKKYLKKDIEYGYRYSM
FKYMKDICILSAEFEFEYKSKQEIKAKLDDIYSLRLSNLPQKPTAGSVFKRPQANMPVGIMVEQLGLKGKQIGDAQISPK
HGGIIVNNGNATGQNILDLIEFIKQQILEHYNIELHEEQIVI
>Mature_281_residues
SEYISLEQYNTYRIKSFAKYVYFPTNNQELLNIVNNHNKLFFLGNGSNVIFSKEYYDDVAFVIFTKKFNSFNIIDNYASV
QAGVLLQDLAFATYNASLSGIETFYDVPASVGGALIMNAGAYGDEIYTCVKSVTILDLNTKQIKKYLKKDIEYGYRYSMF
KYMKDICILSAEFEFEYKSKQEIKAKLDDIYSLRLSNLPQKPTAGSVFKRPQANMPVGIMVEQLGLKGKQIGDAQISPKH
GGIIVNNGNATGQNILDLIEFIKQQILEHYNIELHEEQIVI

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=326, Percent_Identity=25.1533742331288, Blast_Score=98, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 32080; Mature: 31949

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEYISLEQYNTYRIKSFAKYVYFPTNNQELLNIVNNHNKLFFLGNGSNVIFSKEYYDDV
CCCCEECCCCCCCEEEEEEEEEEECCCCHHHHHHHCCCCEEEEEECCCEEEEEHHHHCCE
AFVIFTKKFNSFNIIDNYASVQAGVLLQDLAFATYNASLSGIETFYDVPASVGGALIMNA
EEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHCCCEEEEEC
GAYGDEIYTCVKSVTILDLNTKQIKKYLKKDIEYGYRYSMFKYMKDICILSAEFEFEYKS
CCCCHHHHHHHHHEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEEEEECCCC
KQEIKAKLDDIYSLRLSNLPQKPTAGSVFKRPQANMPVGIMVEQLGLKGKQIGDAQISPK
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCHHHHHHHHCCCCCCCCCCEECCC
HGGIIVNNGNATGQNILDLIEFIKQQILEHYNIELHEEQIVI
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECCCEECC
>Mature Secondary Structure 
SEYISLEQYNTYRIKSFAKYVYFPTNNQELLNIVNNHNKLFFLGNGSNVIFSKEYYDDV
CCCEECCCCCCCEEEEEEEEEEECCCCHHHHHHHCCCCEEEEEECCCEEEEEHHHHCCE
AFVIFTKKFNSFNIIDNYASVQAGVLLQDLAFATYNASLSGIETFYDVPASVGGALIMNA
EEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHCCCEEEEEC
GAYGDEIYTCVKSVTILDLNTKQIKKYLKKDIEYGYRYSMFKYMKDICILSAEFEFEYKS
CCCCHHHHHHHHHEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEEEEECCCC
KQEIKAKLDDIYSLRLSNLPQKPTAGSVFKRPQANMPVGIMVEQLGLKGKQIGDAQISPK
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCHHHHHHHHCCCCCCCCCCEECCC
HGGIIVNNGNATGQNILDLIEFIKQQILEHYNIELHEEQIVI
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA