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The map label for this gene is livM [H]

Identifier: 89054648

GI number: 89054648

Start: 2165382

End: 2166713

Strand: Reverse

Name: livM [H]

Synonym: Jann_2157

Alternate gene names: 89054648

Gene position: 2166713-2165382 (Counterclockwise)

Preceding gene: 89054649

Following gene: 89054640

Centisome position: 50.18

GC content: 63.06

Gene sequence:

>1332_bases
ATGAGTGACGCAACAGCCTCCGCCCCCTCCAGCGTGAACACCAAGAATATCATGCTGTTCGCCCTGGTGGCGATCCTCTT
CCTCGGCACCGGCTTCGTGCAATCCTGGAACACGGCGCTGACGATCTTCAACATGGGCCTGATCAGCTGCATCATGGCGC
TTGGCGTAAACATGCAATGGGGTTATGCGGGCCTCTTCAACGTTGGCATCATGGGCTTCGTGGCGCTCGGCGGCCTCGCC
ACGGTGCTCGTCTCGGTCGAACCGGTCCCCGAGGCGTGGAGCGCGGGCGGCCTGCGCACCTTGATCGGCCTGGTCCTCGG
CGCCTTGACCATCGTCGGCGCGATCCTTCTGTGGAACGCCATGCCGAAGGGCCGATTGCGCGGCATCGCCATGCTGATCG
TCCTGATCATCGGCTTCACCCTCTTCCGCCGTGTCTTTGACGTAGGCGTGGATGCGGTGGAATCCATCGATCCGGCCTCC
ACCGGGTTCCTCGGCGGCCTTGGCCTTCCCGTTTTGCTGGCCTGGCCCGTTGGTGGGCTGCTGGCTGCCGGGGCCGCCTG
GATCATCGGCAAGACGGCCCTTGGCCTGCGGTCCGATTATCTGGCCATCGCCACCCTCGGTATTGCAGAGATCATCATCG
CCATCCTCAAGAATGAAGACTGGCTGGCGCGCGGCGTGAAAAACGTCACCGGCATTGAGCGTCCCGTCCCCTATGAGGTG
GATCTGCAAGCCTCAGACGGCTTCCTGAGCTTCGCCACCAACATCGGCGCGGACCCGGTTACCGCCTCCACGATTACCGT
CAAGCTGCTCTATGCCGCGCTGTTCCTGATCGTTGTGGGCCTGCTGATCTGGCTGTCGGAAAAGGCCTGGAACTCCCCCT
GGGGCCGGATGATGCGCGCGATCCGCGACAATGAAGTCTCGGCCTCGGCCATGGGCAAGGACGTCAAGGCGCGGCATCTG
CAGATTTTCATCCTCGGCTCCGCCATTTGCGGCATTGCTGGTGCGATGATGACCACGCTCGACAGCCAGCTGGTGCCCGG
CACCTACCAACCCCTGCGGTTTACGTTCCTGATCTGGGTCATGGTGATCGTCGGCGGCTCCGGCAACAATTGGGGCGCGG
TCCTGGGCGGCTTCCTGATCTGGTGGCTGTGGGTGCAGGTGGAACCCCTGGGCCTTCTGCTGATGCAAACCATCACGGCG
GGCATGGATGATGGCTATTGGCTGCGGGAGCATCTGCTGGATTCAGCCGCCCATATGCGCCTGTTGACGATGGGCATGAT
CCTCCTGCTGGTCCTGCGCTTCAGCCCCCGTGGCCTGATCCCGGAACGGTAA

Upstream 100 bases:

>100_bases
TGCAACTCCTCTCCACCGACTATAAATTCGCGGTCTCCTTCGGGATCCTGCTGATCGTGCTGCTGTTCAAGCCCACGGGT
ATCATGAAGGGGAAATCGGT

Downstream 100 bases:

>100_bases
AGCCCGTCAGGGCAGAGACCCCCCCGGGGTGCGCAGTCCCGTGACCGATACCGCGAAGACCGGCATCGGAGCCCGGCAGC
CCTACCTGTTGTTGTCCAGA

Product: inner-membrane translocator

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MSDATASAPSSVNTKNIMLFALVAILFLGTGFVQSWNTALTIFNMGLISCIMALGVNMQWGYAGLFNVGIMGFVALGGLA
TVLVSVEPVPEAWSAGGLRTLIGLVLGALTIVGAILLWNAMPKGRLRGIAMLIVLIIGFTLFRRVFDVGVDAVESIDPAS
TGFLGGLGLPVLLAWPVGGLLAAGAAWIIGKTALGLRSDYLAIATLGIAEIIIAILKNEDWLARGVKNVTGIERPVPYEV
DLQASDGFLSFATNIGADPVTASTITVKLLYAALFLIVVGLLIWLSEKAWNSPWGRMMRAIRDNEVSASAMGKDVKARHL
QIFILGSAICGIAGAMMTTLDSQLVPGTYQPLRFTFLIWVMVIVGGSGNNWGAVLGGFLIWWLWVQVEPLGLLLMQTITA
GMDDGYWLREHLLDSAAHMRLLTMGMILLLVLRFSPRGLIPER

Sequences:

>Translated_443_residues
MSDATASAPSSVNTKNIMLFALVAILFLGTGFVQSWNTALTIFNMGLISCIMALGVNMQWGYAGLFNVGIMGFVALGGLA
TVLVSVEPVPEAWSAGGLRTLIGLVLGALTIVGAILLWNAMPKGRLRGIAMLIVLIIGFTLFRRVFDVGVDAVESIDPAS
TGFLGGLGLPVLLAWPVGGLLAAGAAWIIGKTALGLRSDYLAIATLGIAEIIIAILKNEDWLARGVKNVTGIERPVPYEV
DLQASDGFLSFATNIGADPVTASTITVKLLYAALFLIVVGLLIWLSEKAWNSPWGRMMRAIRDNEVSASAMGKDVKARHL
QIFILGSAICGIAGAMMTTLDSQLVPGTYQPLRFTFLIWVMVIVGGSGNNWGAVLGGFLIWWLWVQVEPLGLLLMQTITA
GMDDGYWLREHLLDSAAHMRLLTMGMILLLVLRFSPRGLIPER
>Mature_442_residues
SDATASAPSSVNTKNIMLFALVAILFLGTGFVQSWNTALTIFNMGLISCIMALGVNMQWGYAGLFNVGIMGFVALGGLAT
VLVSVEPVPEAWSAGGLRTLIGLVLGALTIVGAILLWNAMPKGRLRGIAMLIVLIIGFTLFRRVFDVGVDAVESIDPAST
GFLGGLGLPVLLAWPVGGLLAAGAAWIIGKTALGLRSDYLAIATLGIAEIIIAILKNEDWLARGVKNVTGIERPVPYEVD
LQASDGFLSFATNIGADPVTASTITVKLLYAALFLIVVGLLIWLSEKAWNSPWGRMMRAIRDNEVSASAMGKDVKARHLQ
IFILGSAICGIAGAMMTTLDSQLVPGTYQPLRFTFLIWVMVIVGGSGNNWGAVLGGFLIWWLWVQVEPLGLLLMQTITAG
MDDGYWLREHLLDSAAHMRLLTMGMILLLVLRFSPRGLIPER

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789865, Length=212, Percent_Identity=26.4150943396226, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 47383; Mature: 47252

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDATASAPSSVNTKNIMLFALVAILFLGTGFVQSWNTALTIFNMGLISCIMALGVNMQW
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GYAGLFNVGIMGFVALGGLATVLVSVEPVPEAWSAGGLRTLIGLVLGALTIVGAILLWNA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
MPKGRLRGIAMLIVLIIGFTLFRRVFDVGVDAVESIDPASTGFLGGLGLPVLLAWPVGGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCHHHHHHHCHHHH
LAAGAAWIIGKTALGLRSDYLAIATLGIAEIIIAILKNEDWLARGVKNVTGIERPVPYEV
HHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEE
DLQASDGFLSFATNIGADPVTASTITVKLLYAALFLIVVGLLIWLSEKAWNSPWGRMMRA
EECCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
IRDNEVSASAMGKDVKARHLQIFILGSAICGIAGAMMTTLDSQLVPGTYQPLRFTFLIWV
HHCCCCCHHHHCCCCHHHEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
MVIVGGSGNNWGAVLGGFLIWWLWVQVEPLGLLLMQTITAGMDDGYWLREHLLDSAAHMR
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LLTMGMILLLVLRFSPRGLIPER
HHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SDATASAPSSVNTKNIMLFALVAILFLGTGFVQSWNTALTIFNMGLISCIMALGVNMQW
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GYAGLFNVGIMGFVALGGLATVLVSVEPVPEAWSAGGLRTLIGLVLGALTIVGAILLWNA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
MPKGRLRGIAMLIVLIIGFTLFRRVFDVGVDAVESIDPASTGFLGGLGLPVLLAWPVGGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCHHHHHHHCHHHH
LAAGAAWIIGKTALGLRSDYLAIATLGIAEIIIAILKNEDWLARGVKNVTGIERPVPYEV
HHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEE
DLQASDGFLSFATNIGADPVTASTITVKLLYAALFLIVVGLLIWLSEKAWNSPWGRMMRA
EECCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
IRDNEVSASAMGKDVKARHLQIFILGSAICGIAGAMMTTLDSQLVPGTYQPLRFTFLIWV
HHCCCCCHHHHCCCCHHHEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
MVIVGGSGNNWGAVLGGFLIWWLWVQVEPLGLLLMQTITAGMDDGYWLREHLLDSAAHMR
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LLTMGMILLLVLRFSPRGLIPER
HHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]