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The map label for this gene is ycgM [C]

Identifier: 89054596

GI number: 89054596

Start: 2114134

End: 2114982

Strand: Reverse

Name: ycgM [C]

Synonym: Jann_2105

Alternate gene names: 89054596

Gene position: 2114982-2114134 (Counterclockwise)

Preceding gene: 89054597

Following gene: 89054590

Centisome position: 48.98

GC content: 62.31

Gene sequence:

>849_bases
ATGAAACTTTTGCGCTATGGCCCTGTCGGGTCCGAGAAACCCGGAATGCTGGACGCAGATGGCGACCTGCGGGATCTGTC
TGGCGAGGTTGCGGACATTGCGGGCGATATCCTGACACCGGAGGGGTTGGCGCGGCTGGCAGCGTTGGACCCGACATCCC
TTCCGCGTATCGAAGGATCGCCCCGTCTCGGCGCATGTGTGGGCGATGTGGGCAAGATGATCTGCGTCGGCCTGAACTAC
GCCGATCACGCCGCGGAATCGGGCATGGACGTGCCACCCGAGCCGGTGCTGTTTTTCAAGGCCACATCGGCCATTTGCGG
CCCCAACGATGATGTTCGCATCCCGCGAGGGTCCGCAAAAACCGATTGGGAGGTGGAGCTTGGCGTCGTGATCGGCCGTG
AAGCGCGATACGTCGATGAAGCCCACGCCATGGACCATGTGGCGGGCTATTGCATCATCAACGACTTGTCCGAGCGCGCG
TTTCAGATTGAACGCTCCGGTCAATGGGTCAAAGGAAAATCCGCCGATACGTTCGGCCCGACGGGCCCCTGGCTGGTCAC
GAAAGACGAGGTGGAAGATCCCCAGGATCTGGCCATGTGGCTAGAGGTGGACGGGCACCGCTATCAGGACGGCTCCACCC
AGACGATGGTCTACGGCGTGCAGCATCTGGTGCATTACATCAGCCAGTTCATGAGCCTTCAGCCCGGCGACATCATCTCC
ACCGGGACCCCGCCGGGCGTGGGTATGGGTCAGAAGCCGCAGGTCTATCTGCGCGAAGGCCAGGTGATGGAACTGGGCAT
CGCGGGCCTCGGGACGCAGCGGCAACAAACTATCGCCTGGGACGCCTAG

Upstream 100 bases:

>100_bases
AAACTGGCTGTCTATCTGGCCAGCGATGACAGCGCCTTTGTGACCGGTCAGGCCATGGTGGTCGATGGCGGATGGTCGAA
CGTTTGAGGAGTGAGCCAAA

Downstream 100 bases:

>100_bases
GCCAGATATCGAGTGCAGAGATGGCGGTGCGCCTCGGAGATCATCCGCCTAGGCTTGCCACACCGCGCCGCCGGGGAACG
TGTGGCGCGCGATGCTGTGG

Product: 5-carboxymethyl-2-hydroxymuconate delta-isomerase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MKLLRYGPVGSEKPGMLDADGDLRDLSGEVADIAGDILTPEGLARLAALDPTSLPRIEGSPRLGACVGDVGKMICVGLNY
ADHAAESGMDVPPEPVLFFKATSAICGPNDDVRIPRGSAKTDWEVELGVVIGREARYVDEAHAMDHVAGYCIINDLSERA
FQIERSGQWVKGKSADTFGPTGPWLVTKDEVEDPQDLAMWLEVDGHRYQDGSTQTMVYGVQHLVHYISQFMSLQPGDIIS
TGTPPGVGMGQKPQVYLREGQVMELGIAGLGTQRQQTIAWDA

Sequences:

>Translated_282_residues
MKLLRYGPVGSEKPGMLDADGDLRDLSGEVADIAGDILTPEGLARLAALDPTSLPRIEGSPRLGACVGDVGKMICVGLNY
ADHAAESGMDVPPEPVLFFKATSAICGPNDDVRIPRGSAKTDWEVELGVVIGREARYVDEAHAMDHVAGYCIINDLSERA
FQIERSGQWVKGKSADTFGPTGPWLVTKDEVEDPQDLAMWLEVDGHRYQDGSTQTMVYGVQHLVHYISQFMSLQPGDIIS
TGTPPGVGMGQKPQVYLREGQVMELGIAGLGTQRQQTIAWDA
>Mature_282_residues
MKLLRYGPVGSEKPGMLDADGDLRDLSGEVADIAGDILTPEGLARLAALDPTSLPRIEGSPRLGACVGDVGKMICVGLNY
ADHAAESGMDVPPEPVLFFKATSAICGPNDDVRIPRGSAKTDWEVELGVVIGREARYVDEAHAMDHVAGYCIINDLSERA
FQIERSGQWVKGKSADTFGPTGPWLVTKDEVEDPQDLAMWLEVDGHRYQDGSTQTMVYGVQHLVHYISQFMSLQPGDIIS
TGTPPGVGMGQKPQVYLREGQVMELGIAGLGTQRQQTIAWDA

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=228, Percent_Identity=46.0526315789474, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI40786394, Length=202, Percent_Identity=46.039603960396, Blast_Score=199, Evalue=2e-51,
Organism=Homo sapiens, GI215422413, Length=210, Percent_Identity=36.6666666666667, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI66348062, Length=201, Percent_Identity=37.3134328358209, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI13654274, Length=202, Percent_Identity=37.6237623762376, Blast_Score=138, Evalue=5e-33,
Organism=Escherichia coli, GI1787428, Length=182, Percent_Identity=39.010989010989, Blast_Score=132, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17557057, Length=200, Percent_Identity=34.5, Blast_Score=130, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6324161, Length=213, Percent_Identity=31.4553990610329, Blast_Score=97, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28572127, Length=293, Percent_Identity=38.2252559726962, Blast_Score=183, Evalue=9e-47,
Organism=Drosophila melanogaster, GI24663695, Length=237, Percent_Identity=31.6455696202532, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28571789, Length=203, Percent_Identity=34.9753694581281, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 30408; Mature: 30408

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLRYGPVGSEKPGMLDADGDLRDLSGEVADIAGDILTPEGLARLAALDPTSLPRIEGS
CCEEECCCCCCCCCCEECCCCCHHHHCCHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCC
PRLGACVGDVGKMICVGLNYADHAAESGMDVPPEPVLFFKATSAICGPNDDVRIPRGSAK
CCCHHHHHHHHHEEEEECCCHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCEECCCCCCC
TDWEVELGVVIGREARYVDEAHAMDHVAGYCIINDLSERAFQIERSGQWVKGKSADTFGP
CCCEEEEEEEECCCHHHHHHHHHHHHHHHHHEEEHHHHHHEEHHCCCCEEECCCCCCCCC
TGPWLVTKDEVEDPQDLAMWLEVDGHRYQDGSTQTMVYGVQHLVHYISQFMSLQPGDIIS
CCCEEEECCCCCCHHHEEEEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
TGTPPGVGMGQKPQVYLREGQVMELGIAGLGTQRQQTIAWDA
CCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCCCCEEECCC
>Mature Secondary Structure
MKLLRYGPVGSEKPGMLDADGDLRDLSGEVADIAGDILTPEGLARLAALDPTSLPRIEGS
CCEEECCCCCCCCCCEECCCCCHHHHCCHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCC
PRLGACVGDVGKMICVGLNYADHAAESGMDVPPEPVLFFKATSAICGPNDDVRIPRGSAK
CCCHHHHHHHHHEEEEECCCHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCEECCCCCCC
TDWEVELGVVIGREARYVDEAHAMDHVAGYCIINDLSERAFQIERSGQWVKGKSADTFGP
CCCEEEEEEEECCCHHHHHHHHHHHHHHHHHEEEHHHHHHEEHHCCCCEEECCCCCCCCC
TGPWLVTKDEVEDPQDLAMWLEVDGHRYQDGSTQTMVYGVQHLVHYISQFMSLQPGDIIS
CCCEEEECCCCCCHHHEEEEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
TGTPPGVGMGQKPQVYLREGQVMELGIAGLGTQRQQTIAWDA
CCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA