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The map label for this gene is atoS [C]

Identifier: 89054475

GI number: 89054475

Start: 1980629

End: 1982887

Strand: Direct

Name: atoS [C]

Synonym: Jann_1984

Alternate gene names: 89054475

Gene position: 1980629-1982887 (Clockwise)

Preceding gene: 89054474

Following gene: 89054477

Centisome position: 45.87

GC content: 63.75

Gene sequence:

>2259_bases
GTGCAGCCTGTCGTCCTTCTGGTCCTGGGGGTCGTCACGGGCGTGGCCACATGGTTCGCGCCTGGGCCGGAGCTTCGCTT
TGGCCTGATGGCTGCCACCGGTGGCTGCCTGGCCGCTGCGGGCCTTGTTGCCCTGCGCGATATCTGGCGCGTTTGGCGCC
TGCAAAACACGTTTCAGGCGGCGTTTGCGCTGATTGAACATGACCCAGCCCCCAGCTTCTGCACAGATGAAGACGGCGCG
ATTGTCCTGCAGAACGCCGCGGCGGAGCGGCGGTTTGGCGAACGGCTTGGCCTGCCGATGACGCGGGCGATTGCGGGGGC
CTTGCCCAATGCGGCGGCGGTTGTTTTCCGGCAGGAGACTGCCCTTGGGCGGCGACCATCGGCCCATGAAGTTGTCGTCA
CGCCCCGCGGCACGGTGCGCCTTGCGGCCCATCGGTTGAATGGCGGCGTCATTTGGCGGCTGGATGATATGGCCGATGCG
AACTCTCGTCACGGCGAATGGATTGGCCTGCCGATGATGGTCGTCAGCCACAACGACACGGTCCTGTCGATGAATTCCGC
CATGCGGGATGTGCTGGGGCGGCGCGCGACGACGCTGGAAGATGTCTTTCCGGATCAACCGCTTGTGGCGGGCAGACGGT
CCAGCCTGTCGGGCGCGGATGGCAAGATTGAAGTGATCCCGATCGTCGTTCCCTCCAAGGATGGCCGGAGGGAGGTTTAT
GCCGTGCCGGGCCTGTCGGAGCCTCCCGCGGCCTCCGTCGCGGCGCGCGCGTTTGAATCGCTGCCTGTGGCACTCCTGCA
CATCAGCGCGGATGGGGAGGTTTTGGCCTCCAATCACCATGCCCAGAAGTTGCTGGGGATTGAGGCCTCGACCACCGGTC
CGATGGCGCAATTCGTCGAAAACCTGGGCCGTCCCGTGGGCGATTGGGTCGCCGATACCCTGGCTGAGAGGGTGCCCAAC
CGCTCGGAAGTGGCCCGCGCCAAGCAGCGCCGGGATGAGACGTTCCTGCAAATCTCGCTGAGCCGTATTGTCGACGGAAC
CGGGCCATCGCTTCTGGCGGTGCTCCATGATGCGACCGAGTTGAAGACGCTGGAGCAGCAATTCGTCCAGAGCCAGAAAA
TGCAGGCGATCGGAGAGCTTGCGGGCGGCGTGGCCCATGACTTCAACAACCTGCTCACGGCAATCACCGGGCATTGTGAT
TTGCTGCTTCTGCGTCACGACCAGGGCGATCAGGACTACGCGGATCTGGTGCAGATCAACCAGAACGCCAACCGTGCAGC
AAGCCTTGTGGGCCAGCTTCTGGCGTTTTCGCGCAAGCAGACGCTGGAGCCTGAGGTTCTCGATCTGCGCGACTCAATCG
GAGAATTGACTCATCTTCTCAACCGTCTGGTGGGGGAGCGGATTTCGCTATCGCTGTCGAACGATCCTGACCTGGCCCCG
ATCCGCGCCGACCGGCGGCAACTTGATCAGGTGATCATGAACCTTGTGGTGAATGCGCGGGACGCGATGGCCGATGGTGG
CGAGGTCCGGGTCGAGACGCGCATGGTGCATCTGGCCGAGCCGATGTCGCGCGATCAGGCGATTGTGCCCGCTGGATCTT
ACGTGACGATCCGCGTGCGCGATCACGGCCACGGCATTCCGCCCGACAAGCTGCACCGCATTTTCGAGCCGTTCTTCACC
ACCAAACGCACCGGGGAGGGGACGGGTCTGGGCCTGTCGATGGCCTACGGCATCGTCAAGCAAACGGGGGGCTATATCTT
CGTGGACAGCGTCGTCGGCTCTGGCACCACGTTCACAATCTACATTCCGGCCCATGATGTGGTGAACTCAGAGGCCGCTC
CGGATTTGATCGAGGGCAAGGCGACCGAGATCAACGAGGCGCTGGCGGACACACGCCCCGGCGTGGTCCTGTTGGTGGAA
GATGAAGCGCCCGTGCGGGCCTTTGCCTCCCGTGCCCTTCGCCTGCGGGGCTACACGGTGCTGGAGGCCGGTTGCGGAGA
GGAGGCGTTGGACACGCTCGCAGACCCGGAGTTGGAGATTGACCTTTTCGTCACCGACGTGATCATGCCCGGTCTGGATG
GCCCGTCCTGGGTGCGGAAAGCCCTGGAAGAGCGACCGGACACCAAAGTCGTGTTCGTGTCGGGTTATGCGGAGGACGCG
ATGGAGGAGGGGTCGATTGGGGTTGAGGGGTCGGTTTTCCTGCCGAAGCCGTTCTCGCTCACCGACTTGACGGAGACGGT
GCGCCAACAGCTCCAGTAG

Upstream 100 bases:

>100_bases
ACGGCGCGAGCGATCTATCTGACCAGTGGAAGGCGAACAGAAATTGACTGATGAGGCCGTTGACCGTGTTGTGAGCAATG
CTCAGGGGATAAAGCCCTTC

Downstream 100 bases:

>100_bases
AGCCGCTTACCCCCCCAGACGAGCCCAGAGCGCGAATTCCTCCGGTGCCTCGGCGTGCAGACGGGCCTCCATCTCGGCAC
TCAGCACCGCGTCTCGGGCG

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 752; Mature: 752

Protein sequence:

>752_residues
MQPVVLLVLGVVTGVATWFAPGPELRFGLMAATGGCLAAAGLVALRDIWRVWRLQNTFQAAFALIEHDPAPSFCTDEDGA
IVLQNAAAERRFGERLGLPMTRAIAGALPNAAAVVFRQETALGRRPSAHEVVVTPRGTVRLAAHRLNGGVIWRLDDMADA
NSRHGEWIGLPMMVVSHNDTVLSMNSAMRDVLGRRATTLEDVFPDQPLVAGRRSSLSGADGKIEVIPIVVPSKDGRREVY
AVPGLSEPPAASVAARAFESLPVALLHISADGEVLASNHHAQKLLGIEASTTGPMAQFVENLGRPVGDWVADTLAERVPN
RSEVARAKQRRDETFLQISLSRIVDGTGPSLLAVLHDATELKTLEQQFVQSQKMQAIGELAGGVAHDFNNLLTAITGHCD
LLLLRHDQGDQDYADLVQINQNANRAASLVGQLLAFSRKQTLEPEVLDLRDSIGELTHLLNRLVGERISLSLSNDPDLAP
IRADRRQLDQVIMNLVVNARDAMADGGEVRVETRMVHLAEPMSRDQAIVPAGSYVTIRVRDHGHGIPPDKLHRIFEPFFT
TKRTGEGTGLGLSMAYGIVKQTGGYIFVDSVVGSGTTFTIYIPAHDVVNSEAAPDLIEGKATEINEALADTRPGVVLLVE
DEAPVRAFASRALRLRGYTVLEAGCGEEALDTLADPELEIDLFVTDVIMPGLDGPSWVRKALEERPDTKVVFVSGYAEDA
MEEGSIGVEGSVFLPKPFSLTDLTETVRQQLQ

Sequences:

>Translated_752_residues
MQPVVLLVLGVVTGVATWFAPGPELRFGLMAATGGCLAAAGLVALRDIWRVWRLQNTFQAAFALIEHDPAPSFCTDEDGA
IVLQNAAAERRFGERLGLPMTRAIAGALPNAAAVVFRQETALGRRPSAHEVVVTPRGTVRLAAHRLNGGVIWRLDDMADA
NSRHGEWIGLPMMVVSHNDTVLSMNSAMRDVLGRRATTLEDVFPDQPLVAGRRSSLSGADGKIEVIPIVVPSKDGRREVY
AVPGLSEPPAASVAARAFESLPVALLHISADGEVLASNHHAQKLLGIEASTTGPMAQFVENLGRPVGDWVADTLAERVPN
RSEVARAKQRRDETFLQISLSRIVDGTGPSLLAVLHDATELKTLEQQFVQSQKMQAIGELAGGVAHDFNNLLTAITGHCD
LLLLRHDQGDQDYADLVQINQNANRAASLVGQLLAFSRKQTLEPEVLDLRDSIGELTHLLNRLVGERISLSLSNDPDLAP
IRADRRQLDQVIMNLVVNARDAMADGGEVRVETRMVHLAEPMSRDQAIVPAGSYVTIRVRDHGHGIPPDKLHRIFEPFFT
TKRTGEGTGLGLSMAYGIVKQTGGYIFVDSVVGSGTTFTIYIPAHDVVNSEAAPDLIEGKATEINEALADTRPGVVLLVE
DEAPVRAFASRALRLRGYTVLEAGCGEEALDTLADPELEIDLFVTDVIMPGLDGPSWVRKALEERPDTKVVFVSGYAEDA
MEEGSIGVEGSVFLPKPFSLTDLTETVRQQLQ
>Mature_752_residues
MQPVVLLVLGVVTGVATWFAPGPELRFGLMAATGGCLAAAGLVALRDIWRVWRLQNTFQAAFALIEHDPAPSFCTDEDGA
IVLQNAAAERRFGERLGLPMTRAIAGALPNAAAVVFRQETALGRRPSAHEVVVTPRGTVRLAAHRLNGGVIWRLDDMADA
NSRHGEWIGLPMMVVSHNDTVLSMNSAMRDVLGRRATTLEDVFPDQPLVAGRRSSLSGADGKIEVIPIVVPSKDGRREVY
AVPGLSEPPAASVAARAFESLPVALLHISADGEVLASNHHAQKLLGIEASTTGPMAQFVENLGRPVGDWVADTLAERVPN
RSEVARAKQRRDETFLQISLSRIVDGTGPSLLAVLHDATELKTLEQQFVQSQKMQAIGELAGGVAHDFNNLLTAITGHCD
LLLLRHDQGDQDYADLVQINQNANRAASLVGQLLAFSRKQTLEPEVLDLRDSIGELTHLLNRLVGERISLSLSNDPDLAP
IRADRRQLDQVIMNLVVNARDAMADGGEVRVETRMVHLAEPMSRDQAIVPAGSYVTIRVRDHGHGIPPDKLHRIFEPFFT
TKRTGEGTGLGLSMAYGIVKQTGGYIFVDSVVGSGTTFTIYIPAHDVVNSEAAPDLIEGKATEINEALADTRPGVVLLVE
DEAPVRAFASRALRLRGYTVLEAGCGEEALDTLADPELEIDLFVTDVIMPGLDGPSWVRKALEERPDTKVVFVSGYAEDA
MEEGSIGVEGSVFLPKPFSLTDLTETVRQQLQ

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=281, Percent_Identity=32.7402135231317, Blast_Score=123, Evalue=5e-29,
Organism=Escherichia coli, GI1790436, Length=245, Percent_Identity=33.0612244897959, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI145693157, Length=289, Percent_Identity=28.0276816608997, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788713, Length=335, Percent_Identity=26.5671641791045, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI48994928, Length=386, Percent_Identity=25.3886010362694, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786600, Length=359, Percent_Identity=23.1197771587744, Blast_Score=73, Evalue=8e-14,
Organism=Escherichia coli, GI87081816, Length=275, Percent_Identity=25.0909090909091, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790300, Length=280, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786912, Length=261, Percent_Identity=25.6704980842912, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789149, Length=287, Percent_Identity=26.8292682926829, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 81232; Mature: 81232

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPVVLLVLGVVTGVATWFAPGPELRFGLMAATGGCLAAAGLVALRDIWRVWRLQNTFQA
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AFALIEHDPAPSFCTDEDGAIVLQNAAAERRFGERLGLPMTRAIAGALPNAAAVVFRQET
HHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCHHHHHHHCCCCHHEEEEEHHH
ALGRRPSAHEVVVTPRGTVRLAAHRLNGGVIWRLDDMADANSRHGEWIGLPMMVVSHNDT
HCCCCCCCCEEEECCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCEEECEEEEEECCCC
VLSMNSAMRDVLGRRATTLEDVFPDQPLVAGRRSSLSGADGKIEVIPIVVPSKDGRREVY
EEEHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCEEEE
AVPGLSEPPAASVAARAFESLPVALLHISADGEVLASNHHAQKLLGIEASTTGPMAQFVE
ECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCEEECCCCHHHHEECCCCCCCHHHHHHH
NLGRPVGDWVADTLAERVPNRSEVARAKQRRDETFLQISLSRIVDGTGPSLLAVLHDATE
HHCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHEEEHHHHHCCCCCHHHHHHHHHHH
LKTLEQQFVQSQKMQAIGELAGGVAHDFNNLLTAITGHCDLLLLRHDQGDQDYADLVQIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHC
QNANRAASLVGQLLAFSRKQTLEPEVLDLRDSIGELTHLLNRLVGERISLSLSNDPDLAP
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCC
IRADRRQLDQVIMNLVVNARDAMADGGEVRVETRMVHLAEPMSRDQAIVPAGSYVTIRVR
CHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEHHCCCCCCCEEECCCCEEEEEEE
DHGHGIPPDKLHRIFEPFFTTKRTGEGTGLGLSMAYGIVKQTGGYIFVDSVVGSGTTFTI
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEE
YIPAHDVVNSEAAPDLIEGKATEINEALADTRPGVVLLVEDEAPVRAFASRALRLRGYTV
EECCHHHCCCCCCCHHHCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCEEE
LEAGCGEEALDTLADPELEIDLFVTDVIMPGLDGPSWVRKALEERPDTKVVFVSGYAEDA
EECCCCHHHHHHHCCCCEEEEEEEEEHHHCCCCCHHHHHHHHHHCCCCEEEEEECCHHHH
MEEGSIGVEGSVFLPKPFSLTDLTETVRQQLQ
HHCCCCCCCCEEECCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MQPVVLLVLGVVTGVATWFAPGPELRFGLMAATGGCLAAAGLVALRDIWRVWRLQNTFQA
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AFALIEHDPAPSFCTDEDGAIVLQNAAAERRFGERLGLPMTRAIAGALPNAAAVVFRQET
HHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCHHHHHHHCCCCHHEEEEEHHH
ALGRRPSAHEVVVTPRGTVRLAAHRLNGGVIWRLDDMADANSRHGEWIGLPMMVVSHNDT
HCCCCCCCCEEEECCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCEEECEEEEEECCCC
VLSMNSAMRDVLGRRATTLEDVFPDQPLVAGRRSSLSGADGKIEVIPIVVPSKDGRREVY
EEEHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCEEEE
AVPGLSEPPAASVAARAFESLPVALLHISADGEVLASNHHAQKLLGIEASTTGPMAQFVE
ECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCEEECCCCHHHHEECCCCCCCHHHHHHH
NLGRPVGDWVADTLAERVPNRSEVARAKQRRDETFLQISLSRIVDGTGPSLLAVLHDATE
HHCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHEEEHHHHHCCCCCHHHHHHHHHHH
LKTLEQQFVQSQKMQAIGELAGGVAHDFNNLLTAITGHCDLLLLRHDQGDQDYADLVQIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHC
QNANRAASLVGQLLAFSRKQTLEPEVLDLRDSIGELTHLLNRLVGERISLSLSNDPDLAP
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCC
IRADRRQLDQVIMNLVVNARDAMADGGEVRVETRMVHLAEPMSRDQAIVPAGSYVTIRVR
CHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEHHCCCCCCCEEECCCCEEEEEEE
DHGHGIPPDKLHRIFEPFFTTKRTGEGTGLGLSMAYGIVKQTGGYIFVDSVVGSGTTFTI
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEE
YIPAHDVVNSEAAPDLIEGKATEINEALADTRPGVVLLVEDEAPVRAFASRALRLRGYTV
EECCHHHCCCCCCCHHHCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCEEE
LEAGCGEEALDTLADPELEIDLFVTDVIMPGLDGPSWVRKALEERPDTKVVFVSGYAEDA
EECCCCHHHHHHHCCCCEEEEEEEEEHHHCCCCCHHHHHHHHHHCCCCEEEEEECCHHHH
MEEGSIGVEGSVFLPKPFSLTDLTETVRQQLQ
HHCCCCCCCCEEECCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA