Click here to switch to the map view.

The map label for this gene is mocA [H]

Identifier: 89054430

GI number: 89054430

Start: 1929585

End: 1930670

Strand: Reverse

Name: mocA [H]

Synonym: Jann_1939

Alternate gene names: 89054430

Gene position: 1930670-1929585 (Counterclockwise)

Preceding gene: 89054431

Following gene: 89054422

Centisome position: 44.71

GC content: 64.46

Gene sequence:

>1086_bases
ATGACAAGATACGGCCTGATCGGGGCGGGAATGATGGGCCAGGAGCACATCCGCAACATCGCCCTTTTGCCGGACACGGC
CGTGACAGCGATTTATGAGCCCGATGACGCCATGGCCGCGTTGAGCCTTGCGTTGACCGACGGCGCCACGCGCTATGACA
GCCTGAGCGCGCTGTTGACGGGCGCAGAGATCGACGCGCTGGTGATCGCCTCGCCCAACCACTGCCATGTCGCGCAATTG
CAGCAGATCGCGGCCAAAGTGTCCCTGCCGATCCTGTGCGAAAAGCCGCTGTTCACCGCGCCGGACGATGCCGATGCGGT
GGCCGCGCTGGACGCCTACACAGCCCCGATCTGGGTCGCGATGGAATACCGCTACATGCCGCCCATCGCGACCTTCCGCG
AGATGGTGGAGGCGGCCACGGGGGGCATCAAGATGCTGACGATCCGCGAGCACCGCTTTCCGTTCCTGGAGAAGGTCGGC
GACTGGAACCGCTTCAACCGCAATTCCGGCGGCACGCTGGTGGAGAAATGTTGTCATTTCTTTGACCTCATGCGCTTGAT
CTTAAAAGACGAACCGGTACGGGTCATGGCGAGCGCCGGGCAATCGGTGAACCATCTGGACGAGCGCTATGGCGGAGAGA
CGCCGGACATCTGGGACAATGGCTACGTCATCGTCGACTTCAAAGGCGGCGCGCGGGCGATGCTGGAGCTGTGCATGTTC
GCCGAAGGCAGCGAGTATCAGGAAGAGATCAGCGCCGTGGGGCCCAAGGGCAAGATTGAGGCCCGCGTGCCCGGCCCCAC
CCGGTTCTGGAACACCGCCCTTGGCCCCGCGCCGATGCCCAAAGTCGTCGTCAGCCCCCGCGCGCCGACGACCGGACAGG
TGGTGCATGATACGCCGGTGGACAAGGATCTGTTGACCGCAGGCGATCACCACGGATCGACCTATTACCAGCATGTGCAG
TTTCTGGACGTGGTCCGTAACGGCGCCCGCCCCGCCGTCACACTCCGCGATGGGGCGGCGGCGGTGCGCATGGGCATGGC
CGCACAAGACAGCGCGCGGACGGGTCGGGCTGTGGATCTGGCGTAA

Upstream 100 bases:

>100_bases
AGCACGGCCTGCCCTGCGAGGCATCACGGACCTGGTTCGACCCGGACCGCGCGCAATATTTCTCAAAAGTGCCCTGAAGC
GCGGGCGAAGGACGCAGAAC

Downstream 100 bases:

>100_bases
CCGTAACGGCTCCGGTCAGACCGGGCTGGACCATCCCGCGCGCGGTATCGGGGATGCGCGCGGGCGTGCCCCTATCCACA
GCGAAGACGTGACCCGAAAC

Product: oxidoreductase-like protein

Products: 2,4,6/3,5-pentahydroxycyclohexanone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MTRYGLIGAGMMGQEHIRNIALLPDTAVTAIYEPDDAMAALSLALTDGATRYDSLSALLTGAEIDALVIASPNHCHVAQL
QQIAAKVSLPILCEKPLFTAPDDADAVAALDAYTAPIWVAMEYRYMPPIATFREMVEAATGGIKMLTIREHRFPFLEKVG
DWNRFNRNSGGTLVEKCCHFFDLMRLILKDEPVRVMASAGQSVNHLDERYGGETPDIWDNGYVIVDFKGGARAMLELCMF
AEGSEYQEEISAVGPKGKIEARVPGPTRFWNTALGPAPMPKVVVSPRAPTTGQVVHDTPVDKDLLTAGDHHGSTYYQHVQ
FLDVVRNGARPAVTLRDGAAAVRMGMAAQDSARTGRAVDLA

Sequences:

>Translated_361_residues
MTRYGLIGAGMMGQEHIRNIALLPDTAVTAIYEPDDAMAALSLALTDGATRYDSLSALLTGAEIDALVIASPNHCHVAQL
QQIAAKVSLPILCEKPLFTAPDDADAVAALDAYTAPIWVAMEYRYMPPIATFREMVEAATGGIKMLTIREHRFPFLEKVG
DWNRFNRNSGGTLVEKCCHFFDLMRLILKDEPVRVMASAGQSVNHLDERYGGETPDIWDNGYVIVDFKGGARAMLELCMF
AEGSEYQEEISAVGPKGKIEARVPGPTRFWNTALGPAPMPKVVVSPRAPTTGQVVHDTPVDKDLLTAGDHHGSTYYQHVQ
FLDVVRNGARPAVTLRDGAAAVRMGMAAQDSARTGRAVDLA
>Mature_360_residues
TRYGLIGAGMMGQEHIRNIALLPDTAVTAIYEPDDAMAALSLALTDGATRYDSLSALLTGAEIDALVIASPNHCHVAQLQ
QIAAKVSLPILCEKPLFTAPDDADAVAALDAYTAPIWVAMEYRYMPPIATFREMVEAATGGIKMLTIREHRFPFLEKVGD
WNRFNRNSGGTLVEKCCHFFDLMRLILKDEPVRVMASAGQSVNHLDERYGGETPDIWDNGYVIVDFKGGARAMLELCMFA
EGSEYQEEISAVGPKGKIEARVPGPTRFWNTALGPAPMPKVVVSPRAPTTGQVVHDTPVDKDLLTAGDHHGSTYYQHVQF
LDVVRNGARPAVTLRDGAAAVRMGMAAQDSARTGRAVDLA

Specific function: Could catalyze the NADH-dependent dehydrogenase reaction involved in rhizopine (L-3-O-methyl-scyllo-inosamine) catabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87082405, Length=238, Percent_Identity=23.5294117647059, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.1.1.18

Molecular weight: Translated: 39170; Mature: 39039

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRYGLIGAGMMGQEHIRNIALLPDTAVTAIYEPDDAMAALSLALTDGATRYDSLSALLT
CCCCCEEECCCCCHHHHCEEEECCCCCEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHC
GAEIDALVIASPNHCHVAQLQQIAAKVSLPILCEKPLFTAPDDADAVAALDAYTAPIWVA
CCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHCCCEEEE
MEYRYMPPIATFREMVEAATGGIKMLTIREHRFPFLEKVGDWNRFNRNSGGTLVEKCCHF
EEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHCCCCCCCCCCCCCHHHHHHHHH
FDLMRLILKDEPVRVMASAGQSVNHLDERYGGETPDIWDNGYVIVDFKGGARAMLELCMF
HHHHHHHHCCCCCEEHHHCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
AEGSEYQEEISAVGPKGKIEARVPGPTRFWNTALGPAPMPKVVVSPRAPTTGQVVHDTPV
CCCCHHHHHHHHCCCCCCEEEECCCCCHHHHCCCCCCCCCCEEECCCCCCCCCEEECCCC
DKDLLTAGDHHGSTYYQHVQFLDVVRNGARPAVTLRDGAAAVRMGMAAQDSARTGRAVDL
CHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHCCCCCCCCCCCCEECC
A
C
>Mature Secondary Structure 
TRYGLIGAGMMGQEHIRNIALLPDTAVTAIYEPDDAMAALSLALTDGATRYDSLSALLT
CCCCEEECCCCCHHHHCEEEECCCCCEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHC
GAEIDALVIASPNHCHVAQLQQIAAKVSLPILCEKPLFTAPDDADAVAALDAYTAPIWVA
CCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHCCCEEEE
MEYRYMPPIATFREMVEAATGGIKMLTIREHRFPFLEKVGDWNRFNRNSGGTLVEKCCHF
EEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHCCCCCCCCCCCCCHHHHHHHHH
FDLMRLILKDEPVRVMASAGQSVNHLDERYGGETPDIWDNGYVIVDFKGGARAMLELCMF
HHHHHHHHCCCCCEEHHHCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
AEGSEYQEEISAVGPKGKIEARVPGPTRFWNTALGPAPMPKVVVSPRAPTTGQVVHDTPV
CCCCHHHHHHHHCCCCCCEEEECCCCCHHHHCCCCCCCCCCEEECCCCCCCCCEEECCCC
DKDLLTAGDHHGSTYYQHVQFLDVVRNGARPAVTLRDGAAAVRMGMAAQDSARTGRAVDL
CHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHCCCCCCCCCCCCEECC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: myo-inositol; NAD+

Specific reaction: myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]