Click here to switch to the map view.

The map label for this gene is lptD [H]

Identifier: 89054303

GI number: 89054303

Start: 1800779

End: 1802926

Strand: Reverse

Name: lptD [H]

Synonym: Jann_1812

Alternate gene names: 89054303

Gene position: 1802926-1800779 (Counterclockwise)

Preceding gene: 89054304

Following gene: 89054302

Centisome position: 41.75

GC content: 63.22

Gene sequence:

>2148_bases
GTGACCCGCCGTCGTTTGCATATCGCCGCGGTCGTCCTGACCGCCCTTGTCAGCTTCACCTCTCCGGGGGCGGCTCAAAC
GACTGCGCCTGCGACCCTGATCGCTGACAATATCCGCTTCAACGGCTCCTCGACCGTCACGGCGGAGGGGGCGGTTGAAG
TGTTTTTTGGCGGTGCTCGGCTGCGCGCAGAATCGATCACCTACGATGGGACAGCCGACAATCTCCGCGTGCAGGGCCCG
CTGACCTTGGTCGATGAGACCGGATCAACAGTCTTCATTGCCGAATTCGCCGAGTTGTCCGCAGATCTGCAAGAGGGCGT
GCTGCAATCCGCGCGGCTGGTGCTGGACCGGCAGTTGCAGATCGCCGCGACAGAAATCACCCGCACCGAAGGGCGGTATA
CGCAGATCTATCAGGCCGTCGCCTCCTCCTGCGAAGTCTGCTTTGACCACCCGACCCCGCTGTGGGAAATCCGGGCCCGC
CGCGTCATCCACGACGCCGAGGAGCAGCAGCTTTACTTCGACAATGCGCAATTCCGCGTTCTGGGCATCCCGGTGTTCTT
TCTGCCCCGTATGCGGCTGCCCGACCCGACGCTTGAGCGGGCGACGGGGTTTCTGGCACCAACCATTGGCGGCAACAGCA
CCACGGGGCGCCACTTACAGGTGCCCTACTTCATCGAATTGGGTGACCATGCTGATATCACCGTCACGCCCTGGATCGGC
GTGGGCACCCAGACCGTGGACCTGCGTTACCGACAGGCCTTCCGTAACGGGGATTTGACTGCGGTGGGGGCGGCGTCCTG
GGATGACCTGACAACCAGCGCCACACGCGCCTACATGTTCGCCAACGCCAGTTTCAGCTTGCCCCGGGAGTTTCGCCTGG
ATCTGCAAGTTCAGGCCGTCTCGGACCGCGGCTACCTGGCCACATATGGATTTAGCGATACGAACCTGCTGGAAAGCTAC
GCCCGGATCAGCCGTGTCCGGCGTGATGAGTATATCGAAGCCTCCGCCACCGTGTATCAATCCCTACGCGATGGGGTGGA
CAATGACGTTCTGCCCACCCGTGTGGCCCATGCCGAAATCACCCGCCGGATCACGCCTGCAATGATTGGCGGCACGCTGA
CCGCCTCGCTGGAGGGGACGGGCTTTTACCGCTACTCGACCGTTGACGCGACCGCAACGGAGGCCAATGGCCGGGACGTC
TTCCGCATCACCGGCGAGCTGGATTGGCGCCGGTCCCAGACCTTTGGCGGCCTTCTGGCAACCTTTGAGGGCGCTTTGCA
CGGAGGCGTCTACAATACGCAACAGGACCCGGCCTTTGGGACGACCGTGTACCGCCTGACCCCATACGGCGCCGTAGAGC
TGCGCTACCCGGTCCAGGCCATGTCCCCAAGCGGCGTCAGCCACGTGATAGAGCCGGTGGCACAGGTGGTCTGGTCAGAC
ACCTACGGCGATGCAGCACCCAATGAGGACAGCTTCATTGTGGAATTCGACGAGGCCAACCTGTTCTCGCTGGATCGCCT
GCCCGGATCGGACCGGCGCGAAACCGGTGCGCGGGCCAATATCGGGCTCAGCTACAGCCGCATCGCCCCCGACGGCTGGA
CGGTCGGCGTGGGCGGCGGCGTCGTACTGCGCGATGAGGACGAGGGTCAGTTCACCGACGGATCTGGCCTCAACGGCCTG
CAATCGGACTTCATTCTGGCCGCCCACGTCACTTACCCGGGACGCCTGACGCTGATGCAGCGCTCACTTTTTGACCGCGA
TTTGAGCTTCACGTCCAGCGAAGTGTCGCTGTCGTGGTACGGGGAGCGGCACTCGCTCGCCTCCGTCTACACCTTCTTGG
CCGCCGATGAAGGCGAGCAGCGCAGCGATCCCTTGTCAGAACTGCTCTTGGTCGGGAACTACTCCCTTGCCAGCGGCTGG
GACGCGGGCGCGGTCTTCCGCTATGACTTCGCCGAGGATTTCACCACAAACACCGCGTTCACTCTGGGCTACGCGAATGA
GTGCGTGGATATGGAGTTTTCGGTTTCGCGCCGATATACCAACTCCACATCGGTCGCTCCGGCGACGACCTTCGGGCTGA
CGGTGTCTCTGGCAGGCTTTGGGGCCGGACGAGAAGGTCGGTCGGTGTCGCGCAGTTGTCGGGGATGA

Upstream 100 bases:

>100_bases
TGGGCGAAACCGGCCAACTGGCCGCATCCCTGGTGGCCTGGACCCCTCCGATTGCCGCAATTCTCTTGGCGATTGGCTTT
TTATTGCATACGGAGGATGG

Downstream 100 bases:

>100_bases
GGCAAGAGTGTAGGCCAGTGACGAAATCGGACACCGCTGTTGCGGCGGTCAAAAGACGAACGAACAGGGGTTCACGGATG
AACGGCACCTTCTTTGCAGC

Product: organic solvent tolerance protein

Products: NA

Alternate protein names: Organic solvent tolerance protein [H]

Number of amino acids: Translated: 715; Mature: 714

Protein sequence:

>715_residues
MTRRRLHIAAVVLTALVSFTSPGAAQTTAPATLIADNIRFNGSSTVTAEGAVEVFFGGARLRAESITYDGTADNLRVQGP
LTLVDETGSTVFIAEFAELSADLQEGVLQSARLVLDRQLQIAATEITRTEGRYTQIYQAVASSCEVCFDHPTPLWEIRAR
RVIHDAEEQQLYFDNAQFRVLGIPVFFLPRMRLPDPTLERATGFLAPTIGGNSTTGRHLQVPYFIELGDHADITVTPWIG
VGTQTVDLRYRQAFRNGDLTAVGAASWDDLTTSATRAYMFANASFSLPREFRLDLQVQAVSDRGYLATYGFSDTNLLESY
ARISRVRRDEYIEASATVYQSLRDGVDNDVLPTRVAHAEITRRITPAMIGGTLTASLEGTGFYRYSTVDATATEANGRDV
FRITGELDWRRSQTFGGLLATFEGALHGGVYNTQQDPAFGTTVYRLTPYGAVELRYPVQAMSPSGVSHVIEPVAQVVWSD
TYGDAAPNEDSFIVEFDEANLFSLDRLPGSDRRETGARANIGLSYSRIAPDGWTVGVGGGVVLRDEDEGQFTDGSGLNGL
QSDFILAAHVTYPGRLTLMQRSLFDRDLSFTSSEVSLSWYGERHSLASVYTFLAADEGEQRSDPLSELLLVGNYSLASGW
DAGAVFRYDFAEDFTTNTAFTLGYANECVDMEFSVSRRYTNSTSVAPATTFGLTVSLAGFGAGREGRSVSRSCRG

Sequences:

>Translated_715_residues
MTRRRLHIAAVVLTALVSFTSPGAAQTTAPATLIADNIRFNGSSTVTAEGAVEVFFGGARLRAESITYDGTADNLRVQGP
LTLVDETGSTVFIAEFAELSADLQEGVLQSARLVLDRQLQIAATEITRTEGRYTQIYQAVASSCEVCFDHPTPLWEIRAR
RVIHDAEEQQLYFDNAQFRVLGIPVFFLPRMRLPDPTLERATGFLAPTIGGNSTTGRHLQVPYFIELGDHADITVTPWIG
VGTQTVDLRYRQAFRNGDLTAVGAASWDDLTTSATRAYMFANASFSLPREFRLDLQVQAVSDRGYLATYGFSDTNLLESY
ARISRVRRDEYIEASATVYQSLRDGVDNDVLPTRVAHAEITRRITPAMIGGTLTASLEGTGFYRYSTVDATATEANGRDV
FRITGELDWRRSQTFGGLLATFEGALHGGVYNTQQDPAFGTTVYRLTPYGAVELRYPVQAMSPSGVSHVIEPVAQVVWSD
TYGDAAPNEDSFIVEFDEANLFSLDRLPGSDRRETGARANIGLSYSRIAPDGWTVGVGGGVVLRDEDEGQFTDGSGLNGL
QSDFILAAHVTYPGRLTLMQRSLFDRDLSFTSSEVSLSWYGERHSLASVYTFLAADEGEQRSDPLSELLLVGNYSLASGW
DAGAVFRYDFAEDFTTNTAFTLGYANECVDMEFSVSRRYTNSTSVAPATTFGLTVSLAGFGAGREGRSVSRSCRG
>Mature_714_residues
TRRRLHIAAVVLTALVSFTSPGAAQTTAPATLIADNIRFNGSSTVTAEGAVEVFFGGARLRAESITYDGTADNLRVQGPL
TLVDETGSTVFIAEFAELSADLQEGVLQSARLVLDRQLQIAATEITRTEGRYTQIYQAVASSCEVCFDHPTPLWEIRARR
VIHDAEEQQLYFDNAQFRVLGIPVFFLPRMRLPDPTLERATGFLAPTIGGNSTTGRHLQVPYFIELGDHADITVTPWIGV
GTQTVDLRYRQAFRNGDLTAVGAASWDDLTTSATRAYMFANASFSLPREFRLDLQVQAVSDRGYLATYGFSDTNLLESYA
RISRVRRDEYIEASATVYQSLRDGVDNDVLPTRVAHAEITRRITPAMIGGTLTASLEGTGFYRYSTVDATATEANGRDVF
RITGELDWRRSQTFGGLLATFEGALHGGVYNTQQDPAFGTTVYRLTPYGAVELRYPVQAMSPSGVSHVIEPVAQVVWSDT
YGDAAPNEDSFIVEFDEANLFSLDRLPGSDRRETGARANIGLSYSRIAPDGWTVGVGGGVVLRDEDEGQFTDGSGLNGLQ
SDFILAAHVTYPGRLTLMQRSLFDRDLSFTSSEVSLSWYGERHSLASVYTFLAADEGEQRSDPLSELLLVGNYSLASGWD
AGAVFRYDFAEDFTTNTAFTLGYANECVDMEFSVSRRYTNSTSVAPATTFGLTVSLAGFGAGREGRSVSRSCRG

Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis [H]

COG id: COG1452

COG function: function code M; Organic solvent tolerance protein OstA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptD family [H]

Homologues:

Organism=Escherichia coli, GI1786239, Length=589, Percent_Identity=21.5619694397284, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020889
- InterPro:   IPR005653
- InterPro:   IPR007543 [H]

Pfam domain/function: PF03968 OstA; PF04453 OstA_C [H]

EC number: NA

Molecular weight: Translated: 78105; Mature: 77973

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRRLHIAAVVLTALVSFTSPGAAQTTAPATLIADNIRFNGSSTVTAEGAVEVFFGGAR
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECEEECCCCEEEECCCEEEEECCCE
LRAESITYDGTADNLRVQGPLTLVDETGSTVFIAEFAELSADLQEGVLQSARLVLDRQLQ
EEEEEEEECCCCCCEEEECCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEE
IAATEITRTEGRYTQIYQAVASSCEVCFDHPTPLWEIRARRVIHDAEEQQLYFDNAQFRV
EEEEEEECCCCHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCEEE
LGIPVFFLPRMRLPDPTLERATGFLAPTIGGNSTTGRHLQVPYFIELGDHADITVTPWIG
EECCHHEECCCCCCCCHHHHHCCCEEECCCCCCCCCCEEECEEEEEECCCCCEEEECEEC
VGTQTVDLRYRQAFRNGDLTAVGAASWDDLTTSATRAYMFANASFSLPREFRLDLQVQAV
CCCEEEHHHHHHHHCCCCEEEEECCCCCCCCCCHHEEEEEECCCCCCCHHEEEEEEEEEE
SDRGYLATYGFSDTNLLESYARISRVRRDEYIEASATVYQSLRDGVDNDVLPTRVAHAEI
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
TRRITPAMIGGTLTASLEGTGFYRYSTVDATATEANGRDVFRITGELDWRRSQTFGGLLA
HHHCCHHHCCCEEEEEECCCEEEEEEECCCEEECCCCCEEEEEECCCCCCCCCCCCHHHH
TFEGALHGGVYNTQQDPAFGTTVYRLTPYGAVELRYPVQAMSPSGVSHVIEPVAQVVWSD
HHHHHHCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCEECCCCCHHHHHHHHHHHHCCC
TYGDAAPNEDSFIVEFDEANLFSLDRLPGSDRRETGARANIGLSYSRIAPDGWTVGVGGG
CCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCEEEHEECCCCEEEECCCE
VVLRDEDEGQFTDGSGLNGLQSDFILAAHVTYPGRLTLMQRSLFDRDLSFTSSEVSLSWY
EEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCEEHHHHHHHHHCCCCCCCCEEEEEEC
GERHSLASVYTFLAADEGEQRSDPLSELLLVGNYSLASGWDAGAVFRYDFAEDFTTNTAF
CCCHHHHHHHHHHCCCCCCCCCCCHHHEEEECCCCCCCCCCCCCEEEEECHHCCCCCCEE
TLGYANECVDMEFSVSRRYTNSTSVAPATTFGLTVSLAGFGAGREGRSVSRSCRG
EEECCCCEECCEEEECCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCHHHHHCCC
>Mature Secondary Structure 
TRRRLHIAAVVLTALVSFTSPGAAQTTAPATLIADNIRFNGSSTVTAEGAVEVFFGGAR
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECEEECCCCEEEECCCEEEEECCCE
LRAESITYDGTADNLRVQGPLTLVDETGSTVFIAEFAELSADLQEGVLQSARLVLDRQLQ
EEEEEEEECCCCCCEEEECCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEE
IAATEITRTEGRYTQIYQAVASSCEVCFDHPTPLWEIRARRVIHDAEEQQLYFDNAQFRV
EEEEEEECCCCHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCEEE
LGIPVFFLPRMRLPDPTLERATGFLAPTIGGNSTTGRHLQVPYFIELGDHADITVTPWIG
EECCHHEECCCCCCCCHHHHHCCCEEECCCCCCCCCCEEECEEEEEECCCCCEEEECEEC
VGTQTVDLRYRQAFRNGDLTAVGAASWDDLTTSATRAYMFANASFSLPREFRLDLQVQAV
CCCEEEHHHHHHHHCCCCEEEEECCCCCCCCCCHHEEEEEECCCCCCCHHEEEEEEEEEE
SDRGYLATYGFSDTNLLESYARISRVRRDEYIEASATVYQSLRDGVDNDVLPTRVAHAEI
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
TRRITPAMIGGTLTASLEGTGFYRYSTVDATATEANGRDVFRITGELDWRRSQTFGGLLA
HHHCCHHHCCCEEEEEECCCEEEEEEECCCEEECCCCCEEEEEECCCCCCCCCCCCHHHH
TFEGALHGGVYNTQQDPAFGTTVYRLTPYGAVELRYPVQAMSPSGVSHVIEPVAQVVWSD
HHHHHHCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCEECCCCCHHHHHHHHHHHHCCC
TYGDAAPNEDSFIVEFDEANLFSLDRLPGSDRRETGARANIGLSYSRIAPDGWTVGVGGG
CCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCEEEHEECCCCEEEECCCE
VVLRDEDEGQFTDGSGLNGLQSDFILAAHVTYPGRLTLMQRSLFDRDLSFTSSEVSLSWY
EEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCEEHHHHHHHHHCCCCCCCCEEEEEEC
GERHSLASVYTFLAADEGEQRSDPLSELLLVGNYSLASGWDAGAVFRYDFAEDFTTNTAF
CCCHHHHHHHHHHCCCCCCCCCCCHHHEEEECCCCCCCCCCCCCEEEEECHHCCCCCCEE
TLGYANECVDMEFSVSRRYTNSTSVAPATTFGLTVSLAGFGAGREGRSVSRSCRG
EEECCCCEECCEEEECCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA