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The map label for this gene is gapB [H]

Identifier: 89054186

GI number: 89054186

Start: 1677817

End: 1678818

Strand: Reverse

Name: gapB [H]

Synonym: Jann_1695

Alternate gene names: 89054186

Gene position: 1678818-1677817 (Counterclockwise)

Preceding gene: 89054187

Following gene: 89054185

Centisome position: 38.88

GC content: 62.67

Gene sequence:

>1002_bases
ATGGCCGTCAAAGTCGCCATCAACGGATTTGGTCGCATCGGACGCAACGTGCTGCGCGCCATCATCGAATCCGGTCGCAC
CGACATCGAAGTCGTCGCCATCAACGATCTGGGCCCGGTGGAAACCAACGCCCACCTCCTGCGCTACGACTCGGTCCATG
GCCGCTTCCCCGCCACGGTGACGACGACGGACACAACCATCGACGTCGGTCGCGGGCCCATCGATGTGACGGCGATCCGC
AACCCCGCCGATCTGCCCTGGGGCCATGTGGACATCGTGCTGGAATGCACCGGCATCTTCACCTCGAAAGAGGCCTGCCA
AGCCCATCTGGAAAACGGATCAAGCCGCGTCCTGATCTCCGCCCCCGGCAAGGACGCCGACAAGACAATCGTTTACGGCG
TGAATGACAGCGCGCTGACCTCGGACGACATCATCGTCTCCAACGCGTCGTGCACGACAAACTGCCTGTCGCCCGTGGCC
CATGTCCTGCACTCGGAGATCGGCATCGTCAAAGGCTTCATGACGACGATCCACTCCTACACCGGCGATCAGCCGACGCT
CGATACGATGCATAAGGATCTCTACCGTGCCCGCGCCGCCGCGCTGTCGATGATCCCCACCTCCACGGGGGCCGCGAAAG
CCGTGGGTCTGGTGCTGCCGGACCTGGCGGGGAAACTGGATGGCGTCGCGATCCGCGTGCCCACCCCCAATGTCTCTGTC
GTCGACCTGACGTTTGAGGCCGCCCGCGCGACCTCGGTGGACGAGATCAACGACGCCATCCGCAAAGCTGCAAACGGTCC
TCTGAAAGGCATCCTCGGCGTCACCGACGAGAAACTCGTCAGCCAGGACTTCAACCACGACCCCCATTCCTCGATCTTCG
CCACCGACCAGACCAAGGTGATGGAGGGCACGATGGTCCGCATCCTGACATGGTATGACAACGAATGGGGCTTCTCCAAC
CGGATGAGCGACACGGCCGTGGCCATGGGCAAACTGATCTGA

Upstream 100 bases:

>100_bases
AGCCCCTTCCCAAGCGCGGCTGCACGGGCTAAGACGGCCCTGTTACCGCTAACACACATTTCGCCGCCGTCGCGCGGCGC
ACTCAGCAGGAGGCTCTCCC

Downstream 100 bases:

>100_bases
ACCGGCAAACGGGCGCATATGTCTAAAATTGCGCCCGCCCCCGCCCGGCCACCAATCCGCCGCCCTCCACAGCAGACGCG
TCGGTCTCGCCCCACGGCCT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MAVKVAINGFGRIGRNVLRAIIESGRTDIEVVAINDLGPVETNAHLLRYDSVHGRFPATVTTTDTTIDVGRGPIDVTAIR
NPADLPWGHVDIVLECTGIFTSKEACQAHLENGSSRVLISAPGKDADKTIVYGVNDSALTSDDIIVSNASCTTNCLSPVA
HVLHSEIGIVKGFMTTIHSYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPDLAGKLDGVAIRVPTPNVSV
VDLTFEAARATSVDEINDAIRKAANGPLKGILGVTDEKLVSQDFNHDPHSSIFATDQTKVMEGTMVRILTWYDNEWGFSN
RMSDTAVAMGKLI

Sequences:

>Translated_333_residues
MAVKVAINGFGRIGRNVLRAIIESGRTDIEVVAINDLGPVETNAHLLRYDSVHGRFPATVTTTDTTIDVGRGPIDVTAIR
NPADLPWGHVDIVLECTGIFTSKEACQAHLENGSSRVLISAPGKDADKTIVYGVNDSALTSDDIIVSNASCTTNCLSPVA
HVLHSEIGIVKGFMTTIHSYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPDLAGKLDGVAIRVPTPNVSV
VDLTFEAARATSVDEINDAIRKAANGPLKGILGVTDEKLVSQDFNHDPHSSIFATDQTKVMEGTMVRILTWYDNEWGFSN
RMSDTAVAMGKLI
>Mature_332_residues
AVKVAINGFGRIGRNVLRAIIESGRTDIEVVAINDLGPVETNAHLLRYDSVHGRFPATVTTTDTTIDVGRGPIDVTAIRN
PADLPWGHVDIVLECTGIFTSKEACQAHLENGSSRVLISAPGKDADKTIVYGVNDSALTSDDIIVSNASCTTNCLSPVAH
VLHSEIGIVKGFMTTIHSYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPDLAGKLDGVAIRVPTPNVSVV
DLTFEAARATSVDEINDAIRKAANGPLKGILGVTDEKLVSQDFNHDPHSSIFATDQTKVMEGTMVRILTWYDNEWGFSNR
MSDTAVAMGKLI

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=331, Percent_Identity=47.1299093655589, Blast_Score=296, Evalue=2e-80,
Organism=Homo sapiens, GI7657116, Length=326, Percent_Identity=46.319018404908, Blast_Score=279, Evalue=3e-75,
Organism=Escherichia coli, GI1789295, Length=334, Percent_Identity=47.6047904191617, Blast_Score=305, Evalue=2e-84,
Organism=Escherichia coli, GI1788079, Length=327, Percent_Identity=48.0122324159021, Blast_Score=301, Evalue=4e-83,
Organism=Caenorhabditis elegans, GI17534679, Length=330, Percent_Identity=47.8787878787879, Blast_Score=296, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI17534677, Length=330, Percent_Identity=47.8787878787879, Blast_Score=295, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI32566163, Length=330, Percent_Identity=46.969696969697, Blast_Score=283, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI17568413, Length=330, Percent_Identity=46.969696969697, Blast_Score=283, Evalue=1e-76,
Organism=Saccharomyces cerevisiae, GI6321631, Length=328, Percent_Identity=49.0853658536585, Blast_Score=295, Evalue=5e-81,
Organism=Saccharomyces cerevisiae, GI6322409, Length=328, Percent_Identity=47.2560975609756, Blast_Score=295, Evalue=5e-81,
Organism=Saccharomyces cerevisiae, GI6322468, Length=328, Percent_Identity=47.5609756097561, Blast_Score=288, Evalue=6e-79,
Organism=Drosophila melanogaster, GI17933600, Length=325, Percent_Identity=48.9230769230769, Blast_Score=293, Evalue=1e-79,
Organism=Drosophila melanogaster, GI18110149, Length=325, Percent_Identity=48.9230769230769, Blast_Score=293, Evalue=1e-79,
Organism=Drosophila melanogaster, GI85725000, Length=325, Percent_Identity=48, Blast_Score=288, Evalue=3e-78,
Organism=Drosophila melanogaster, GI22023983, Length=325, Percent_Identity=48, Blast_Score=288, Evalue=3e-78,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=43.3846153846154, Blast_Score=264, Evalue=7e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35519; Mature: 35388

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKVAINGFGRIGRNVLRAIIESGRTDIEVVAINDLGPVETNAHLLRYDSVHGRFPATV
CEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCEEE
TTTDTTIDVGRGPIDVTAIRNPADLPWGHVDIVLECTGIFTSKEACQAHLENGSSRVLIS
EECCCEEECCCCCEEEEEECCCCCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCEEEEE
APGKDADKTIVYGVNDSALTSDDIIVSNASCTTNCLSPVAHVLHSEIGIVKGFMTTIHSY
CCCCCCCCEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPDLAGKLDGVAIRVPTPNVSV
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCEE
VDLTFEAARATSVDEINDAIRKAANGPLKGILGVTDEKLVSQDFNHDPHSSIFATDQTKV
EEEEEHHHHCCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHCCCCCCCCCEEECCCCCH
MEGTMVRILTWYDNEWGFSNRMSDTAVAMGKLI
HCCEEEEEEEEECCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
AVKVAINGFGRIGRNVLRAIIESGRTDIEVVAINDLGPVETNAHLLRYDSVHGRFPATV
EEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCEEE
TTTDTTIDVGRGPIDVTAIRNPADLPWGHVDIVLECTGIFTSKEACQAHLENGSSRVLIS
EECCCEEECCCCCEEEEEECCCCCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCEEEEE
APGKDADKTIVYGVNDSALTSDDIIVSNASCTTNCLSPVAHVLHSEIGIVKGFMTTIHSY
CCCCCCCCEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPDLAGKLDGVAIRVPTPNVSV
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCEE
VDLTFEAARATSVDEINDAIRKAANGPLKGILGVTDEKLVSQDFNHDPHSSIFATDQTKV
EEEEEHHHHCCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHCCCCCCCCCEEECCCCCH
MEGTMVRILTWYDNEWGFSNRMSDTAVAMGKLI
HCCEEEEEEEEECCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1939098 [H]