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The map label for this gene is atpD

Identifier: 89053540

GI number: 89053540

Start: 1003869

End: 1005293

Strand: Direct

Name: atpD

Synonym: Jann_1049

Alternate gene names: 89053540

Gene position: 1003869-1005293 (Clockwise)

Preceding gene: 89053539

Following gene: 89053541

Centisome position: 23.25

GC content: 62.04

Gene sequence:

>1425_bases
ATGGCAAATGCAGTCGGCAAAATTACCCAGGTCATCGGCGCTGTCGTTGACGTGCAGTTCAATGATCACCTGCCAGAGAT
CCTGAACGCGCTGGAAACCGAAAACGACGGGAAGCGTCTGGTGCTTGAGGTTGCTCAGCATCTGGGCGAGGGCACCGTGC
GCACGATCGCGATGGACAGCTCCGAAGGTCTGGTGCGGGGCCAGGAGGTGACCGACACCGACGGGCCGATCACGGTTCCC
GTGGGTCCCGGCACACTGGGTCGGATCCTCAACGTCGTGGGGGAGCCGGTGGATGAAGGCGGCCCCGTCGACGCAGAAGA
GCGTCGCGGCATCCACCAGGATGCGCCTGAGTTCGCCGACCAGTCGACCGAGGCCGAAGTCCTTGTGACGGGCATCAAGG
TTGTGGACCTGCTGGCGCCGTATTCCAAGGGTGGTAAGATTGGCCTCTTCGGTGGTGCCGGCGTGGGCAAGACGGTTCTG
ATCATGGAGCTGATCAACAACATCGCGAAGGTGCACTCCGGTGTGTCCGTGTTCGCCGGTGTGGGCGAGCGGACCCGTGA
GGGCAACGACCTCTACCACGAGATGATCGAATCCGGCGTTATCGTCCCCGATAACCTGCCTGAGTCGAAGATCGCTTTGG
TCTATGGCCAGATGAACGAGCCTCCCGGTGCGCGGATGCGGATCGCTTTGTCCGGTCTGACATTGGCCGAGCAGTTCCGG
GATGCGACGGGCGCGGACGTGTTGTTCTTCATCGACAACATCTTCCGCTTTACCCAGGCCGGGTCCGAGGTTTCGGCGCT
TCTGGGTCGTATCCCCTCCGCCGTGGGCTATCAGCCGACGCTGGCGACGGATATGGGCACGATGCAGGAACGCATTACGT
CCACCAAACGCGGCTCGATCACGTCCATTCAGGCCGTCTACGTGCCTGCGGACGACCTGACCGACCCTGCGCCTGCCACG
ACATTTGCCCACCTTGACGCCACGACCGTTTTGTCGCGCGCCATCTCCGAGCTTGGGATCTACCCGGCTGTGGACCCGCT
CGACAGCTCCTCGCGTCTGATGGACCCGACCATCGTTGGTGACGAGCACTACCAGGTCGCCCGTGACGTCCAGGGTATCC
TCCAGCGCTACAAGTCGTTGCAGGACATCATCGCCATTCTCGGCATGGACGAACTGTCGGAAGAGGACAAGCTGACCGTG
GCCCGCGCCCGGAAGATCCAGCGCTTCCTGTCCCAGCCGTTCGACGTGGCGAAGGTGTTCACCGGCTCCGATGGTATTCA
GGTGCAGTTGGAAGACACGATCTCGTCCTTCAAGGCCGTGGTTGCGGGTGAGTATGATCACCTGCCGGAAGGTGCGTTCT
ACATGGTCGGCGGGATCGACGAAGTGATCGCCAAGGCCGAAAAGATGGCAGCCGACGCGGCTTGA

Upstream 100 bases:

>100_bases
TGACCATCGAGTATAACCGCTCGCGTCAGGCCGTCATCACCAGCGAGCTGATCGAAATTATCTCGGGCGCTGAAGCGCTT
TAACGACGGAGAGACGACAC

Downstream 100 bases:

>100_bases
TCTAAGCGGGCCGCCAGCCCGCCCTGCCTCCCCTCCCGTCCACCTAGGATGCCAAATCCGACGGTGGACCCCTGGTGGAC
GGGAGGGGAGGCGGGGCGGG

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MANAVGKITQVIGAVVDVQFNDHLPEILNALETENDGKRLVLEVAQHLGEGTVRTIAMDSSEGLVRGQEVTDTDGPITVP
VGPGTLGRILNVVGEPVDEGGPVDAEERRGIHQDAPEFADQSTEAEVLVTGIKVVDLLAPYSKGGKIGLFGGAGVGKTVL
IMELINNIAKVHSGVSVFAGVGERTREGNDLYHEMIESGVIVPDNLPESKIALVYGQMNEPPGARMRIALSGLTLAEQFR
DATGADVLFFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITSTKRGSITSIQAVYVPADDLTDPAPAT
TFAHLDATTVLSRAISELGIYPAVDPLDSSSRLMDPTIVGDEHYQVARDVQGILQRYKSLQDIIAILGMDELSEEDKLTV
ARARKIQRFLSQPFDVAKVFTGSDGIQVQLEDTISSFKAVVAGEYDHLPEGAFYMVGGIDEVIAKAEKMAADAA

Sequences:

>Translated_474_residues
MANAVGKITQVIGAVVDVQFNDHLPEILNALETENDGKRLVLEVAQHLGEGTVRTIAMDSSEGLVRGQEVTDTDGPITVP
VGPGTLGRILNVVGEPVDEGGPVDAEERRGIHQDAPEFADQSTEAEVLVTGIKVVDLLAPYSKGGKIGLFGGAGVGKTVL
IMELINNIAKVHSGVSVFAGVGERTREGNDLYHEMIESGVIVPDNLPESKIALVYGQMNEPPGARMRIALSGLTLAEQFR
DATGADVLFFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITSTKRGSITSIQAVYVPADDLTDPAPAT
TFAHLDATTVLSRAISELGIYPAVDPLDSSSRLMDPTIVGDEHYQVARDVQGILQRYKSLQDIIAILGMDELSEEDKLTV
ARARKIQRFLSQPFDVAKVFTGSDGIQVQLEDTISSFKAVVAGEYDHLPEGAFYMVGGIDEVIAKAEKMAADAA
>Mature_473_residues
ANAVGKITQVIGAVVDVQFNDHLPEILNALETENDGKRLVLEVAQHLGEGTVRTIAMDSSEGLVRGQEVTDTDGPITVPV
GPGTLGRILNVVGEPVDEGGPVDAEERRGIHQDAPEFADQSTEAEVLVTGIKVVDLLAPYSKGGKIGLFGGAGVGKTVLI
MELINNIAKVHSGVSVFAGVGERTREGNDLYHEMIESGVIVPDNLPESKIALVYGQMNEPPGARMRIALSGLTLAEQFRD
ATGADVLFFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITSTKRGSITSIQAVYVPADDLTDPAPATT
FAHLDATTVLSRAISELGIYPAVDPLDSSSRLMDPTIVGDEHYQVARDVQGILQRYKSLQDIIAILGMDELSEEDKLTVA
RARKIQRFLSQPFDVAKVFTGSDGIQVQLEDTISSFKAVVAGEYDHLPEGAFYMVGGIDEVIAKAEKMAADAA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=471, Percent_Identity=77.7070063694268, Blast_Score=736, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=322, Percent_Identity=29.8136645962733, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI19913426, Length=367, Percent_Identity=25.3405994550409, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI19913428, Length=367, Percent_Identity=26.158038147139, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI50345984, Length=299, Percent_Identity=24.4147157190635, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI4757810, Length=299, Percent_Identity=24.4147157190635, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI1790170, Length=467, Percent_Identity=69.593147751606, Blast_Score=650, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=358, Percent_Identity=30.1675977653631, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1790172, Length=437, Percent_Identity=23.5697940503432, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25144756, Length=469, Percent_Identity=74.8400852878465, Blast_Score=715, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17510931, Length=350, Percent_Identity=26.5714285714286, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17565854, Length=303, Percent_Identity=29.3729372937294, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17570191, Length=352, Percent_Identity=26.1363636363636, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71988080, Length=321, Percent_Identity=23.0529595015576, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71988063, Length=321, Percent_Identity=23.0529595015576, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71988074, Length=273, Percent_Identity=22.3443223443223, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322581, Length=460, Percent_Identity=75.8695652173913, Blast_Score=699, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=366, Percent_Identity=26.775956284153, Blast_Score=107, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6319370, Length=432, Percent_Identity=25.2314814814815, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6320016, Length=262, Percent_Identity=27.4809160305344, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24638766, Length=469, Percent_Identity=78.0383795309168, Blast_Score=737, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=467, Percent_Identity=71.0920770877944, Blast_Score=656, Evalue=0.0,
Organism=Drosophila melanogaster, GI24638768, Length=90, Percent_Identity=73.3333333333333, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24583992, Length=322, Percent_Identity=29.5031055900621, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24583988, Length=304, Percent_Identity=29.6052631578947, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24583986, Length=304, Percent_Identity=29.6052631578947, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24583984, Length=304, Percent_Identity=29.6052631578947, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI20129479, Length=303, Percent_Identity=28.0528052805281, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI281361666, Length=355, Percent_Identity=26.1971830985915, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24646341, Length=355, Percent_Identity=26.1971830985915, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI17136796, Length=355, Percent_Identity=26.1971830985915, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24658560, Length=299, Percent_Identity=23.4113712374582, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB_JANSC (Q28TJ6)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_508991.1
- HSSP:   P10719
- ProteinModelPortal:   Q28TJ6
- SMR:   Q28TJ6
- STRING:   Q28TJ6
- GeneID:   3933493
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_1049
- eggNOG:   COG0055
- HOGENOM:   HBG565875
- OMA:   IGQEHYD
- PhylomeDB:   Q28TJ6
- ProtClustDB:   PRK09280
- BioCyc:   JSP290400:JANN_1049-MONOMER
- HAMAP:   MF_01347
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 50557; Mature: 50426

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANAVGKITQVIGAVVDVQFNDHLPEILNALETENDGKRLVLEVAQHLGEGTVRTIAMDS
CCCHHHHHHHHHHHHHEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEECC
SEGLVRGQEVTDTDGPITVPVGPGTLGRILNVVGEPVDEGGPVDAEERRGIHQDAPEFAD
CCCCEECCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCHHHHC
QSTEAEVLVTGIKVVDLLAPYSKGGKIGLFGGAGVGKTVLIMELINNIAKVHSGVSVFAG
CCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHC
VGERTREGNDLYHEMIESGVIVPDNLPESKIALVYGQMNEPPGARMRIALSGLTLAEQFR
CCCCCCCCHHHHHHHHHCCEECCCCCCCCCEEEEEECCCCCCCCEEEEEECCHHHHHHHC
DATGADVLFFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITSTKRGSI
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHCCCCCC
TSIQAVYVPADDLTDPAPATTFAHLDATTVLSRAISELGIYPAVDPLDSSSRLMDPTIVG
EEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEC
DEHYQVARDVQGILQRYKSLQDIIAILGMDELSEEDKLTVARARKIQRFLSQPFDVAKVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCCCCCHHEE
TGSDGIQVQLEDTISSFKAVVAGEYDHLPEGAFYMVGGIDEVIAKAEKMAADAA
ECCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ANAVGKITQVIGAVVDVQFNDHLPEILNALETENDGKRLVLEVAQHLGEGTVRTIAMDS
CCHHHHHHHHHHHHHEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEECC
SEGLVRGQEVTDTDGPITVPVGPGTLGRILNVVGEPVDEGGPVDAEERRGIHQDAPEFAD
CCCCEECCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCHHHHC
QSTEAEVLVTGIKVVDLLAPYSKGGKIGLFGGAGVGKTVLIMELINNIAKVHSGVSVFAG
CCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHC
VGERTREGNDLYHEMIESGVIVPDNLPESKIALVYGQMNEPPGARMRIALSGLTLAEQFR
CCCCCCCCHHHHHHHHHCCEECCCCCCCCCEEEEEECCCCCCCCEEEEEECCHHHHHHHC
DATGADVLFFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITSTKRGSI
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHCCCCCC
TSIQAVYVPADDLTDPAPATTFAHLDATTVLSRAISELGIYPAVDPLDSSSRLMDPTIVG
EEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEC
DEHYQVARDVQGILQRYKSLQDIIAILGMDELSEEDKLTVARARKIQRFLSQPFDVAKVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCCCCCHHEE
TGSDGIQVQLEDTISSFKAVVAGEYDHLPEGAFYMVGGIDEVIAKAEKMAADAA
ECCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA