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The map label for this gene is sucC

Identifier: 89053312

GI number: 89053312

Start: 778221

End: 779414

Strand: Direct

Name: sucC

Synonym: Jann_0821

Alternate gene names: 89053312

Gene position: 778221-779414 (Clockwise)

Preceding gene: 89053311

Following gene: 89053313

Centisome position: 18.02

GC content: 60.64

Gene sequence:

>1194_bases
ATGAACATTCATGAGTATCAGGCGAAAGCCCTTCTCGCGCAATACGGCGCTCCGGTGTCTGACGGACGCGTTGTCACGAA
GGCGGAAGACGCCAAGACCGCCGCCGGAGAGATGGACGGGCCGCTTTGGGTCGTGAAAGCGCAGATCCACGCGGGCGGCC
GCGGCAAGGGCAAGTTCAAGGAAGCTGACGCTGGAGAGGCGGGCGGTGTGCGCCTTGCGAAATCCGCGCAGGAGGCAGCG
GACGAGGCCAAGAAGATGTTGGGCCGCACGCTTGTGACGCACCAGACCGGCCCCGTAGGCAAGCAGGTTAACCGGATCTA
CATCGAAGACGGCTCGGGCATCGAGACCGAGATGTATCTGGCGCTTCTGGTGGATCGCCAGTCCAGCCGCATCAGCTTTG
TCTGCTCCACCGAAGGTGGCATGGACATCGAAGAGGTCGCCGCGTCGACGCCTGAAAAAATCCTCAGCTTCTCCGTCGAT
CCGGCCACGGGCTACCAGCCTTACCATGGTCGCCGCGTGGCGTTTTCGCTGGGGCTTGAGGGGCAACAGGTCAAGCAATG
CGTCAAGCTGATGGGTCAGCTCTTCACCGCCTTCCAGGAGAAGGACATGGAGATGCTGGAGATCAACCCGCTGATCGTGA
CGGATGAAGGCAACCTCAAAGTGCTCGATGCGAAGGTCAGTTTTGACGGCAACGCTGTCTACCGCCACGCCGATGTGGCG
TCCTTGCGGGACGAGACGGAAGAGGACCCCAAGGAACTGGCCGCGTCCAAGTTCGACCTCAACTACATCGCGCTCGACGG
TGAAATCGGCTGCATGGTCAACGGCGCGGGCCTGGCCATGGCGACGATGGATATCATCAAGCTTTATGGCGCGGAGCCTG
CAAACTTCCTCGACGTGGGCGGCGGCGCGACCAAGGAGAAGGTGACGGAGGCGTTCAAAATCATCACTTCTGACCCGCAG
GTGAAGGGCATTTTCGTTAACATCTTCGGCGGCATCATGCGCTGCGATATCATCGCGGAAGGCGTGATCGCAGCGGTGAA
AGAGGTCGGCCTGCAAATGCCGCTGGTGGTGCGTCTGGAAGGCACGAACGTGGAGAAGGGCAAGGAGATCATCAACAATT
CCGGCCTCGACGTGATCGCCGCCGACGACCTGAAAGACGGCGCGCAGAAGATCGTGAAGGCTGTGAAGGGATAG

Upstream 100 bases:

>100_bases
TTTGCGGCTAATCCTATGAAATATGGCGAATTGCCGTTCCATTGCGCGCAGAGGTTGTGTTTACCTGAGCAGAACTTGAC
CCAACGAACGGACCTTTTTC

Downstream 100 bases:

>100_bases
AGCAACATGCCGCTCGCTCGCCTTCTGACTGCCGTCCTCTGCCTTGCGTTGATCGGGTGCGGGATACCGCCGCTGAACAC
TGCAACTGTCAGTCAAACTC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MNIHEYQAKALLAQYGAPVSDGRVVTKAEDAKTAAGEMDGPLWVVKAQIHAGGRGKGKFKEADAGEAGGVRLAKSAQEAA
DEAKKMLGRTLVTHQTGPVGKQVNRIYIEDGSGIETEMYLALLVDRQSSRISFVCSTEGGMDIEEVAASTPEKILSFSVD
PATGYQPYHGRRVAFSLGLEGQQVKQCVKLMGQLFTAFQEKDMEMLEINPLIVTDEGNLKVLDAKVSFDGNAVYRHADVA
SLRDETEEDPKELAASKFDLNYIALDGEIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGATKEKVTEAFKIITSDPQ
VKGIFVNIFGGIMRCDIIAEGVIAAVKEVGLQMPLVVRLEGTNVEKGKEIINNSGLDVIAADDLKDGAQKIVKAVKG

Sequences:

>Translated_397_residues
MNIHEYQAKALLAQYGAPVSDGRVVTKAEDAKTAAGEMDGPLWVVKAQIHAGGRGKGKFKEADAGEAGGVRLAKSAQEAA
DEAKKMLGRTLVTHQTGPVGKQVNRIYIEDGSGIETEMYLALLVDRQSSRISFVCSTEGGMDIEEVAASTPEKILSFSVD
PATGYQPYHGRRVAFSLGLEGQQVKQCVKLMGQLFTAFQEKDMEMLEINPLIVTDEGNLKVLDAKVSFDGNAVYRHADVA
SLRDETEEDPKELAASKFDLNYIALDGEIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGATKEKVTEAFKIITSDPQ
VKGIFVNIFGGIMRCDIIAEGVIAAVKEVGLQMPLVVRLEGTNVEKGKEIINNSGLDVIAADDLKDGAQKIVKAVKG
>Mature_397_residues
MNIHEYQAKALLAQYGAPVSDGRVVTKAEDAKTAAGEMDGPLWVVKAQIHAGGRGKGKFKEADAGEAGGVRLAKSAQEAA
DEAKKMLGRTLVTHQTGPVGKQVNRIYIEDGSGIETEMYLALLVDRQSSRISFVCSTEGGMDIEEVAASTPEKILSFSVD
PATGYQPYHGRRVAFSLGLEGQQVKQCVKLMGQLFTAFQEKDMEMLEINPLIVTDEGNLKVLDAKVSFDGNAVYRHADVA
SLRDETEEDPKELAASKFDLNYIALDGEIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGATKEKVTEAFKIITSDPQ
VKGIFVNIFGGIMRCDIIAEGVIAAVKEVGLQMPLVVRLEGTNVEKGKEIINNSGLDVIAADDLKDGAQKIVKAVKG

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=393, Percent_Identity=43.765903307888, Blast_Score=336, Evalue=3e-92,
Organism=Homo sapiens, GI157779135, Length=386, Percent_Identity=45.5958549222798, Blast_Score=330, Evalue=1e-90,
Organism=Homo sapiens, GI294862256, Length=366, Percent_Identity=45.3551912568306, Blast_Score=308, Evalue=8e-84,
Organism=Escherichia coli, GI1786948, Length=397, Percent_Identity=53.6523929471033, Blast_Score=418, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17539378, Length=395, Percent_Identity=44.0506329113924, Blast_Score=335, Evalue=2e-92,
Organism=Caenorhabditis elegans, GI17567829, Length=392, Percent_Identity=43.1122448979592, Blast_Score=318, Evalue=4e-87,
Organism=Saccharomyces cerevisiae, GI6321683, Length=396, Percent_Identity=44.6969696969697, Blast_Score=346, Evalue=4e-96,
Organism=Drosophila melanogaster, GI21356231, Length=396, Percent_Identity=46.4646464646465, Blast_Score=352, Evalue=2e-97,
Organism=Drosophila melanogaster, GI161078106, Length=388, Percent_Identity=47.680412371134, Blast_Score=350, Evalue=8e-97,
Organism=Drosophila melanogaster, GI24645208, Length=388, Percent_Identity=47.680412371134, Blast_Score=350, Evalue=8e-97,
Organism=Drosophila melanogaster, GI281361397, Length=389, Percent_Identity=47.8149100257069, Blast_Score=348, Evalue=3e-96,
Organism=Drosophila melanogaster, GI281361395, Length=389, Percent_Identity=47.8149100257069, Blast_Score=348, Evalue=3e-96,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_JANSC (Q28U74)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_508763.1
- HSSP:   P53590
- ProteinModelPortal:   Q28U74
- SMR:   Q28U74
- STRING:   Q28U74
- GeneID:   3933264
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_0821
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   RREFYFA
- PhylomeDB:   Q28U74
- ProtClustDB:   PRK00696
- BioCyc:   JSP290400:JANN_0821-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 42429; Mature: 42429

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKALLAQYGAPVSDGRVVTKAEDAKTAAGEMDGPLWVVKAQIHAGGRGKGKFK
CCCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCCCCCCEEEEEEEEECCCCCCCCCC
EADAGEAGGVRLAKSAQEAADEAKKMLGRTLVTHQTGPVGKQVNRIYIEDGSGIETEMYL
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHEEE
ALLVDRQSSRISFVCSTEGGMDIEEVAASTPEKILSFSVDPATGYQPYHGRRVAFSLGLE
EEEEECCCCCEEEEEECCCCCCHHHHHCCCCHHHHEEECCCCCCCCCCCCCEEEEEECCC
GQQVKQCVKLMGQLFTAFQEKDMEMLEINPLIVTDEGNLKVLDAKVSFDGNAVYRHADVA
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCEEEEEEEEECCCCEEEEECHHH
SLRDETEEDPKELAASKFDLNYIALDGEIGCMVNGAGLAMATMDIIKLYGAEPANFLDVG
HHHHCCCCCHHHHHHHHCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGATKEKVTEAFKIITSDPQVKGIFVNIFGGIMRCDIIAEGVIAAVKEVGLQMPLVVRLE
CCCCHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GTNVEKGKEIINNSGLDVIAADDLKDGAQKIVKAVKG
CCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQAKALLAQYGAPVSDGRVVTKAEDAKTAAGEMDGPLWVVKAQIHAGGRGKGKFK
CCCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCCCCCCEEEEEEEEECCCCCCCCCC
EADAGEAGGVRLAKSAQEAADEAKKMLGRTLVTHQTGPVGKQVNRIYIEDGSGIETEMYL
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHEEE
ALLVDRQSSRISFVCSTEGGMDIEEVAASTPEKILSFSVDPATGYQPYHGRRVAFSLGLE
EEEEECCCCCEEEEEECCCCCCHHHHHCCCCHHHHEEECCCCCCCCCCCCCEEEEEECCC
GQQVKQCVKLMGQLFTAFQEKDMEMLEINPLIVTDEGNLKVLDAKVSFDGNAVYRHADVA
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCEEEEEEEEECCCCEEEEECHHH
SLRDETEEDPKELAASKFDLNYIALDGEIGCMVNGAGLAMATMDIIKLYGAEPANFLDVG
HHHHCCCCCHHHHHHHHCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGATKEKVTEAFKIITSDPQVKGIFVNIFGGIMRCDIIAEGVIAAVKEVGLQMPLVVRLE
CCCCHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GTNVEKGKEIINNSGLDVIAADDLKDGAQKIVKAVKG
CCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA