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The map label for this gene is glcD [H]

Identifier: 89053181

GI number: 89053181

Start: 662764

End: 664209

Strand: Direct

Name: glcD [H]

Synonym: Jann_0690

Alternate gene names: 89053181

Gene position: 662764-664209 (Clockwise)

Preceding gene: 89053177

Following gene: 89053182

Centisome position: 15.35

GC content: 63.69

Gene sequence:

>1446_bases
ATGCAAATGCCCACACCTGACGCCCGCGTTCTGGCCCGCAAAGCGCGGATCGTCGAACGCCTGCTGACTGTCCTGCCGAA
AACGGCCGTCATCCATGAGGACGCGGAAACCAAGGCCTATGAATGCGATGCGCTGACGGCCTACAGATGCCCGCCGCTGG
CCGCGATCCTGCCGTCCTCGACCGAAGAAGTCGCCGCCGCCCTGAAGATTTGCCATGAGGAAGGCGTGCCGGTTGTGCCG
CGCGGTGCTGGCACGTCCCTGGCCGGTGGGTCGCTGCCCACTGCCGATAGCGTGATCCTGGGCGTGGCGCGGATGAACCA
GGTGCTGGAGACGGATTATGAGAACCGCGTGATCCGCGTGCAAAGCGGGCGCACCAATCTGTCGGTGACCGGCGCGGTGG
AGGCGGAGGAGTTCTTCTACGCCCCCGACCCGTCCTCGCAACTGGCCTGTGCCATCGCGGGCAATATCGCGATGAATTCC
GGCGGGGCCCATTGCCTGAAATACGGCGTGACCACCAACAATCTTCTGGGCGTGAAACTGGTGACGATGGAAGGGGACGT
GCTGGAGATTGGCGGCGCGCATCTCGATAGCGGCAATTATGACCTTCTGGGCCTGATCTGCGGCAGCGAAGGGCAGTTGG
GCGTGGTGACCGAGGCGACGTTGCGGATCCTGCGCAAGCCCGAAGGGGCGCGGCCCGTGCTGATCGGGTTCGACAGCAAC
GAAGTGGCGGGCGCCTGCGTCAGCGATATCATCAAGGCAGGCGTCCTGCCCGTGGCGATTGAATTCATGGACCGTCCGAT
CCTGGAGATTGCGGAAAACCACGCCAAGGCGGGCTACCCCGATTGCGAAGCGGTGCTGATCGTGGAGGTGGAGGGATCGC
CGTCCGAGATCGACGCGCAGCTTGGCCTGATCAAGCAAATCGCGCGGTCTCACAATCCGGTGGATCTGCGGGAGGCTGAG
ACAGCGGAGGAAGCGGCCCGCATCTGGCTTGGCCGCAAAAGTGCCTTCGGGGCCGTGGGGCAAGTGGCCGATTACATGTG
CCTCGACGGGACAATCCCCGTGGGGGAACTGCCGCGCGTGCTGACCGGGATCAAGGAGATTGGCGATAAGTACGGGCTGA
AAGTGGGCAATGTGTTCCATGCGGGTGATGGCAACATGCATCCGCTGATCATGTTTGACGCCAACAAGCCTGGCGATCTG
GAGTTATGCGAGGCCTGCGGGGCGGATATCCTGAGGCTATGCGTGGAGGTCGGCGGGTGCCTGACCGGAGAGCATGGCGT
GGGGGTGGAGAAGCGCGACCTGATGGGCGCGCAGTTCACCGATGCGGATATGGAGGCGCAGATGCGGGTGAAGGATGTGT
TTGACCCCGCGTGGCTGCTGAACCCCGCGAAGGTGTTCCCGCTGGAGACGTCACAGGGCCGGAGGGAGAGAAATTTCGCC
GCCTGA

Upstream 100 bases:

>100_bases
TGCGGCATCGCTGCAGGGCGAAAACAATTGCCATACGGCCATATTGGTTATATTATTTTACCAATTCGCGGATCTTGCCC
GCATGATGGGAGGAAAGCCA

Downstream 100 bases:

>100_bases
CGGCGTCGACCAACCGGGGGATGTCATCCCCCGGACCCCCCTGAACGGGGGGCTGTCCGCCCCCTATGTGTCTTTCCCGA
AAGGGAAAGATCACAGACCC

Product: FAD linked oxidase-like protein

Products: 2-oxo acid; H2O2

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MQMPTPDARVLARKARIVERLLTVLPKTAVIHEDAETKAYECDALTAYRCPPLAAILPSSTEEVAAALKICHEEGVPVVP
RGAGTSLAGGSLPTADSVILGVARMNQVLETDYENRVIRVQSGRTNLSVTGAVEAEEFFYAPDPSSQLACAIAGNIAMNS
GGAHCLKYGVTTNNLLGVKLVTMEGDVLEIGGAHLDSGNYDLLGLICGSEGQLGVVTEATLRILRKPEGARPVLIGFDSN
EVAGACVSDIIKAGVLPVAIEFMDRPILEIAENHAKAGYPDCEAVLIVEVEGSPSEIDAQLGLIKQIARSHNPVDLREAE
TAEEAARIWLGRKSAFGAVGQVADYMCLDGTIPVGELPRVLTGIKEIGDKYGLKVGNVFHAGDGNMHPLIMFDANKPGDL
ELCEACGADILRLCVEVGGCLTGEHGVGVEKRDLMGAQFTDADMEAQMRVKDVFDPAWLLNPAKVFPLETSQGRRERNFA
A

Sequences:

>Translated_481_residues
MQMPTPDARVLARKARIVERLLTVLPKTAVIHEDAETKAYECDALTAYRCPPLAAILPSSTEEVAAALKICHEEGVPVVP
RGAGTSLAGGSLPTADSVILGVARMNQVLETDYENRVIRVQSGRTNLSVTGAVEAEEFFYAPDPSSQLACAIAGNIAMNS
GGAHCLKYGVTTNNLLGVKLVTMEGDVLEIGGAHLDSGNYDLLGLICGSEGQLGVVTEATLRILRKPEGARPVLIGFDSN
EVAGACVSDIIKAGVLPVAIEFMDRPILEIAENHAKAGYPDCEAVLIVEVEGSPSEIDAQLGLIKQIARSHNPVDLREAE
TAEEAARIWLGRKSAFGAVGQVADYMCLDGTIPVGELPRVLTGIKEIGDKYGLKVGNVFHAGDGNMHPLIMFDANKPGDL
ELCEACGADILRLCVEVGGCLTGEHGVGVEKRDLMGAQFTDADMEAQMRVKDVFDPAWLLNPAKVFPLETSQGRRERNFA
A
>Mature_481_residues
MQMPTPDARVLARKARIVERLLTVLPKTAVIHEDAETKAYECDALTAYRCPPLAAILPSSTEEVAAALKICHEEGVPVVP
RGAGTSLAGGSLPTADSVILGVARMNQVLETDYENRVIRVQSGRTNLSVTGAVEAEEFFYAPDPSSQLACAIAGNIAMNS
GGAHCLKYGVTTNNLLGVKLVTMEGDVLEIGGAHLDSGNYDLLGLICGSEGQLGVVTEATLRILRKPEGARPVLIGFDSN
EVAGACVSDIIKAGVLPVAIEFMDRPILEIAENHAKAGYPDCEAVLIVEVEGSPSEIDAQLGLIKQIARSHNPVDLREAE
TAEEAARIWLGRKSAFGAVGQVADYMCLDGTIPVGELPRVLTGIKEIGDKYGLKVGNVFHAGDGNMHPLIMFDANKPGDL
ELCEACGADILRLCVEVGGCLTGEHGVGVEKRDLMGAQFTDADMEAQMRVKDVFDPAWLLNPAKVFPLETSQGRRERNFA
A

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI37595756, Length=431, Percent_Identity=28.7703016241299, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI37595754, Length=454, Percent_Identity=27.5330396475771, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI119964728, Length=444, Percent_Identity=28.6036036036036, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI4501993, Length=226, Percent_Identity=25.6637168141593, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1789351, Length=445, Percent_Identity=48.7640449438202, Blast_Score=425, Evalue=1e-120,
Organism=Escherichia coli, GI1787977, Length=504, Percent_Identity=25.1984126984127, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI48994907, Length=488, Percent_Identity=22.7459016393443, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71992373, Length=428, Percent_Identity=24.5327102803738, Blast_Score=169, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI71992381, Length=425, Percent_Identity=23.5294117647059, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17534361, Length=445, Percent_Identity=26.5168539325843, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71992392, Length=362, Percent_Identity=22.3756906077348, Blast_Score=131, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6320027, Length=437, Percent_Identity=28.604118993135, Blast_Score=189, Evalue=8e-49,
Organism=Saccharomyces cerevisiae, GI6320764, Length=479, Percent_Identity=25.2609603340292, Blast_Score=149, Evalue=8e-37,
Organism=Saccharomyces cerevisiae, GI6320023, Length=452, Percent_Identity=25, Blast_Score=137, Evalue=3e-33,
Organism=Drosophila melanogaster, GI18921117, Length=456, Percent_Identity=25.8771929824561, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24639277, Length=456, Percent_Identity=25.8771929824561, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24639275, Length=456, Percent_Identity=25.8771929824561, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24653753, Length=221, Percent_Identity=25.3393665158371, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: 1.1.3.15

Molecular weight: Translated: 51122; Mature: 51122

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMPTPDARVLARKARIVERLLTVLPKTAVIHEDAETKAYECDALTAYRCPPLAAILPSS
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCEEECCCEEEECCCCCCEECCCC
TEEVAAALKICHEEGVPVVPRGAGTSLAGGSLPTADSVILGVARMNQVLETDYENRVIRV
HHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEE
QSGRTNLSVTGAVEAEEFFYAPDPSSQLACAIAGNIAMNSGGAHCLKYGVTTNNLLGVKL
ECCCCEEEEEEEEEHHHEEECCCCCCCEEEEEECCEEECCCCCEEEEECCCCCCEEEEEE
VTMEGDVLEIGGAHLDSGNYDLLGLICGSEGQLGVVTEATLRILRKPEGARPVLIGFDSN
EEECCCEEEECCCEECCCCCEEEEEEECCCCCEEEEHHHHHHHHHCCCCCCCEEEECCCC
EVAGACVSDIIKAGVLPVAIEFMDRPILEIAENHAKAGYPDCEAVLIVEVEGSPSEIDAQ
CHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHH
LGLIKQIARSHNPVDLREAETAEEAARIWLGRKSAFGAVGQVADYMCLDGTIPVGELPRV
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCCCCHHHHHHH
LTGIKEIGDKYGLKVGNVFHAGDGNMHPLIMFDANKPGDLELCEACGADILRLCVEVGGC
HHHHHHHHHHHCCEECCEEECCCCCCCEEEEECCCCCCCHHHHHHCCHHHHHHHHHHCCC
LTGEHGVGVEKRDLMGAQFTDADMEAQMRVKDVFDPAWLLNPAKVFPLETSQGRRERNFA
CCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHCCCHHHCCCCCEEEECCCCCCCCCCCC
A
C
>Mature Secondary Structure
MQMPTPDARVLARKARIVERLLTVLPKTAVIHEDAETKAYECDALTAYRCPPLAAILPSS
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCEEECCCEEEECCCCCCEECCCC
TEEVAAALKICHEEGVPVVPRGAGTSLAGGSLPTADSVILGVARMNQVLETDYENRVIRV
HHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEE
QSGRTNLSVTGAVEAEEFFYAPDPSSQLACAIAGNIAMNSGGAHCLKYGVTTNNLLGVKL
ECCCCEEEEEEEEEHHHEEECCCCCCCEEEEEECCEEECCCCCEEEEECCCCCCEEEEEE
VTMEGDVLEIGGAHLDSGNYDLLGLICGSEGQLGVVTEATLRILRKPEGARPVLIGFDSN
EEECCCEEEECCCEECCCCCEEEEEEECCCCCEEEEHHHHHHHHHCCCCCCCEEEECCCC
EVAGACVSDIIKAGVLPVAIEFMDRPILEIAENHAKAGYPDCEAVLIVEVEGSPSEIDAQ
CHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHH
LGLIKQIARSHNPVDLREAETAEEAARIWLGRKSAFGAVGQVADYMCLDGTIPVGELPRV
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCCCCHHHHHHH
LTGIKEIGDKYGLKVGNVFHAGDGNMHPLIMFDANKPGDLELCEACGADILRLCVEVGGC
HHHHHHHHHHHCCEECCEEECCCCCCCEEEEECCCCCCCHHHHHHCCHHHHHHHHHHCCC
LTGEHGVGVEKRDLMGAQFTDADMEAQMRVKDVFDPAWLLNPAKVFPLETSQGRRERNFA
CCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHCCCHHHCCCCCEEEECCCCCCCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-2-hydroxy acid; O2

Specific reaction: (S)-2-hydroxy acid + O2 = 2-oxo acid + H2O2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]