Click here to switch to the map view.

The map label for this gene is prtE [H]

Identifier: 88658225

GI number: 88658225

Start: 992890

End: 994407

Strand: Direct

Name: prtE [H]

Synonym: ECH_0970

Alternate gene names: 88658225

Gene position: 992890-994407 (Clockwise)

Preceding gene: 88658628

Following gene: 88658170

Centisome position: 84.41

GC content: 30.7

Gene sequence:

>1518_bases
ATGTATCAAAAACTCAAAAATCTCATAAAAGTAGGGTTTTCACTACCAAAACTTTTAGGACATAACACACTACATCTAGA
AGATAGTGAAGAAAAATCAAGATCAAGCATACTAACTAAATCACTGTTTATTATAGACAACATAATAAACTTTTTATTTA
AGTACAACAGAAAGGATTCAGTAAATGAGGTATTGAAAATATCATGGGGTCCGCTATTCACTGGATTTATCATTATTTTA
CTCTTTTTTGGCATATTTGGAATATGGTCTGCAGTAGCACCACTCGATGGATCAGTAATTGCACAAGGAGAAGTTATTCC
TTCATCAGAAAAACAAATAATCCAACATTTAGAAGGTGGCATCATTAATAAGATCCTAGTCAAGGAAGGAGAATTAGTAC
AAAAAAATCAGCCTATAATATCTTTACATAATACTACAGCTAAAGCCAATCTAGACATTATAAAAGAACGAGTACTTGAT
CTATTAGCAACAGAGGCTAGGTTAGTTGCTATAAAATACAATTATGAATCTCTAATCTTTCCAGACACTCTAAAAAATCT
ATCAGATGAAAAAACAAGAATACAAATAATAAAAAATCAGCAACAGTTATTTGAGTCGCACAAGAAGAACGTATCCGGAC
AAATAGATATTTTACAACAACGTATAAAACAGCTACACCAAGAATTATCCGGGTTATCTGCTCAACTAACTTCAGCAATC
ACTCAACATAAATTAATTAATGAAGAATTAGAAACAAAAAAAAGCCTGTTAGAGAATGGATATATTAGCAAACCATATAT
TATTGCACTTGAACGTCAATATGCTGAATCCAAAGGGAAAATAGGACAAATTAAATCTGCTATTGCATCAGTAAATCAAA
AAATTGGAGAAAATAAATTAGAAATAATTAATATTACCAACAATGTGCAAAATAAAATCAATCTTGAACTTAAAGATGTA
ACATCTGCCATAACAGACCTAAAAGAAAAGATGAAAACTGCTCAAGACATATTGGATAGAACTATAATAAGGTCTCCTCA
AGCCGGCATCATAACAGGATTAAAATACCACACAGAAGGTGGAGTAATACCTCCTGGAGCTCCCATAACAAACGTTGTAC
CACTAAATGACGATTTAATTATAGATGCAAAAATACAAACAAGGCATATTGAAGAAATTCTATCTGCACAAATGAAAGAT
AAAAATATAGTATCATATGAGAACTATCATGGATTAAAAGCAAAAGTACGCCTAAGTGCATATAACATACGTAAAATTGG
ATTAGTAAATGGAATAGTAGTACAAGTATCAGCTGATGCTTTAAGTGAAGTCAATGGAATGCGTTACTATAAAATACAAG
TAATAATACCAAAAGAACAATCTGCAAAGCTAAAAAATTTAAAATTGTATCCTGGAATGCCAGCAGAAGTTTTTATAATT
ACTCAATCTCGCACTTTGTTTAACTATCTGTTCACTCCAATAACTAGTACTTTTGAAAAAGCTTTTAATGAAAGATAA

Upstream 100 bases:

>100_bases
CAAGTAAAGATATTTTAAGATATTTATCTGATAAATAGTGCATTATAATATTTACCAAATATGCTATAAATTAAATGTTA
CACTTATTATATTATACACT

Downstream 100 bases:

>100_bases
AATTGGATTAGTAAATGGAATAGTAGTACAGTATCAGCTGATGCTTTAAGCGAAGTTAATTGGAATACGTTACCATAAAA
TACAAGTAATAATACCAAGA

Product: HlyD family type I secretion membrane fusion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MYQKLKNLIKVGFSLPKLLGHNTLHLEDSEEKSRSSILTKSLFIIDNIINFLFKYNRKDSVNEVLKISWGPLFTGFIIIL
LFFGIFGIWSAVAPLDGSVIAQGEVIPSSEKQIIQHLEGGIINKILVKEGELVQKNQPIISLHNTTAKANLDIIKERVLD
LLATEARLVAIKYNYESLIFPDTLKNLSDEKTRIQIIKNQQQLFESHKKNVSGQIDILQQRIKQLHQELSGLSAQLTSAI
TQHKLINEELETKKSLLENGYISKPYIIALERQYAESKGKIGQIKSAIASVNQKIGENKLEIINITNNVQNKINLELKDV
TSAITDLKEKMKTAQDILDRTIIRSPQAGIITGLKYHTEGGVIPPGAPITNVVPLNDDLIIDAKIQTRHIEEILSAQMKD
KNIVSYENYHGLKAKVRLSAYNIRKIGLVNGIVVQVSADALSEVNGMRYYKIQVIIPKEQSAKLKNLKLYPGMPAEVFII
TQSRTLFNYLFTPITSTFEKAFNER

Sequences:

>Translated_505_residues
MYQKLKNLIKVGFSLPKLLGHNTLHLEDSEEKSRSSILTKSLFIIDNIINFLFKYNRKDSVNEVLKISWGPLFTGFIIIL
LFFGIFGIWSAVAPLDGSVIAQGEVIPSSEKQIIQHLEGGIINKILVKEGELVQKNQPIISLHNTTAKANLDIIKERVLD
LLATEARLVAIKYNYESLIFPDTLKNLSDEKTRIQIIKNQQQLFESHKKNVSGQIDILQQRIKQLHQELSGLSAQLTSAI
TQHKLINEELETKKSLLENGYISKPYIIALERQYAESKGKIGQIKSAIASVNQKIGENKLEIINITNNVQNKINLELKDV
TSAITDLKEKMKTAQDILDRTIIRSPQAGIITGLKYHTEGGVIPPGAPITNVVPLNDDLIIDAKIQTRHIEEILSAQMKD
KNIVSYENYHGLKAKVRLSAYNIRKIGLVNGIVVQVSADALSEVNGMRYYKIQVIIPKEQSAKLKNLKLYPGMPAEVFII
TQSRTLFNYLFTPITSTFEKAFNER
>Mature_505_residues
MYQKLKNLIKVGFSLPKLLGHNTLHLEDSEEKSRSSILTKSLFIIDNIINFLFKYNRKDSVNEVLKISWGPLFTGFIIIL
LFFGIFGIWSAVAPLDGSVIAQGEVIPSSEKQIIQHLEGGIINKILVKEGELVQKNQPIISLHNTTAKANLDIIKERVLD
LLATEARLVAIKYNYESLIFPDTLKNLSDEKTRIQIIKNQQQLFESHKKNVSGQIDILQQRIKQLHQELSGLSAQLTSAI
TQHKLINEELETKKSLLENGYISKPYIIALERQYAESKGKIGQIKSAIASVNQKIGENKLEIINITNNVQNKINLELKDV
TSAITDLKEKMKTAQDILDRTIIRSPQAGIITGLKYHTEGGVIPPGAPITNVVPLNDDLIIDAKIQTRHIEEILSAQMKD
KNIVSYENYHGLKAKVRLSAYNIRKIGLVNGIVVQVSADALSEVNGMRYYKIQVIIPKEQSAKLKNLKLYPGMPAEVFII
TQSRTLFNYLFTPITSTFEKAFNER

Specific function: Involved in the secretion of proteases A, B, C and G [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 56872; Mature: 56872

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQKLKNLIKVGFSLPKLLGHNTLHLEDSEEKSRSSILTKSLFIIDNIINFLFKYNRKDS
CHHHHHHHHHHCCHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VNEVLKISWGPLFTGFIIILLFFGIFGIWSAVAPLDGSVIAQGEVIPSSEKQIIQHLEGG
HHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHCCC
IINKILVKEGELVQKNQPIISLHNTTAKANLDIIKERVLDLLATEARLVAIKYNYESLIF
HHHHHHHCCCCHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEC
PDTLKNLSDEKTRIQIIKNQQQLFESHKKNVSGQIDILQQRIKQLHQELSGLSAQLTSAI
CHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQHKLINEELETKKSLLENGYISKPYIIALERQYAESKGKIGQIKSAIASVNQKIGENKL
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHCCCCE
EIINITNNVQNKINLELKDVTSAITDLKEKMKTAQDILDRTIIRSPQAGIITGLKYHTEG
EEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECEEEECCC
GVIPPGAPITNVVPLNDDLIIDAKIQTRHIEEILSAQMKDKNIVSYENYHGLKAKVRLSA
CCCCCCCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEEEE
YNIRKIGLVNGIVVQVSADALSEVNGMRYYKIQVIIPKEQSAKLKNLKLYPGMPAEVFII
ECEEEEEEECCEEEEEEHHHHHHCCCCEEEEEEEEEECCCCCCCCCEEECCCCCCEEEEE
TQSRTLFNYLFTPITSTFEKAFNER
ECCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYQKLKNLIKVGFSLPKLLGHNTLHLEDSEEKSRSSILTKSLFIIDNIINFLFKYNRKDS
CHHHHHHHHHHCCHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VNEVLKISWGPLFTGFIIILLFFGIFGIWSAVAPLDGSVIAQGEVIPSSEKQIIQHLEGG
HHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHCCC
IINKILVKEGELVQKNQPIISLHNTTAKANLDIIKERVLDLLATEARLVAIKYNYESLIF
HHHHHHHCCCCHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEC
PDTLKNLSDEKTRIQIIKNQQQLFESHKKNVSGQIDILQQRIKQLHQELSGLSAQLTSAI
CHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQHKLINEELETKKSLLENGYISKPYIIALERQYAESKGKIGQIKSAIASVNQKIGENKL
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHCCCCE
EIINITNNVQNKINLELKDVTSAITDLKEKMKTAQDILDRTIIRSPQAGIITGLKYHTEG
EEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECEEEECCC
GVIPPGAPITNVVPLNDDLIIDAKIQTRHIEEILSAQMKDKNIVSYENYHGLKAKVRLSA
CCCCCCCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEEEE
YNIRKIGLVNGIVVQVSADALSEVNGMRYYKIQVIIPKEQSAKLKNLKLYPGMPAEVFII
ECEEEEEEECCEEEEEEHHHHHHCCCCEEEEEEEEEECCCCCCCCCEEECCCCCCEEEEE
TQSRTLFNYLFTPITSTFEKAFNER
ECCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2184029 [H]