Click here to switch to the map view.

The map label for this gene is rpoC [H]

Identifier: 88657749

GI number: 88657749

Start: 971864

End: 976096

Strand: Reverse

Name: rpoC [H]

Synonym: ECH_0951

Alternate gene names: 88657749

Gene position: 976096-971864 (Counterclockwise)

Preceding gene: 88658392

Following gene: 88658397

Centisome position: 82.98

GC content: 33.1

Gene sequence:

>4233_bases
ATGAAGATGTTGGATTTGTATGGCTATACTAGTATTGCGCAATCGTTTGATAAGATTTGCATATCTATAGCTAGTCCTGA
AAGCATTAGAGCAATGTCGTATGGTGAAATTAAAGATATTTCTACTACTAATTACCGTACGTTTAAAGTGGAAAAGGGAG
GTCTTTTTTGTCCTAAAATTTTTGGGCCAGTTAATGATGATGAATGTTTGTGCGGTAAGTATCGAAAAAAGCGTTATAGA
GGCGTAGTTTGTGAAAAGTGTGGAGTTGAAGTTACATCATCTAAGGTGCGTAGAGAAAGAATGGGACATATAGAACTTGT
ATCTCCTGTAGCACATGTTTGGTTTTTGAAATCTCTGCCTTCGCGTATAGGTGCATTACTTGATATGCCGCTTAAGTTGA
TAGAAAATATTTTATATAGTGGTGATTTTGTAGTTATTGATCCAATTGCAACTCCATTGTCTAAGGGTGAAGTTATTAGT
GAAAGTGCTTACAATCAAGCAAAAGATAATTATGGAGAAGATAGTTTTCTTGCTTTAACTGGAGCTGAAGCTATTAGGGA
GTTGTTAGTGCGGTTGGATTTGCATGCAATTAATGCAAATCTTAGAGTAGAGTTGGAATCTACAACTTCAGAAATGAAGA
GAAAAAAAATAGTAAAAAGATTGCGTATTGTTGAGAATTTTATAAATTCTGGTAACAAACCTGAGTGGATGATATTAACA
GTTATACCAATTTTGCCACCTGATTTAAGACCACTTGTTTCTTTAGAAAATGGAAGACCAGCAGTTTCTGATTTAAACCA
TCATTATCGGACAATTATTAACCGTAATAATAGATTGGGTAAGTTATTAAAATTAAATCCACCTGCGATTATGATCCGTA
ATGAAAAGAGAATGCTACAAGAAGCAGTAGATGCTCTTTTTGATAGTACACGTCGTAGCTATGTTTCTAATAAGGCAGGG
AGTGTAGGGTACAAGAAATCATTAAGTGATATGTTAAAGGGCAAGCAAGGGCGTTTTAGACAAAACTTGCTAGGAAAAAG
GGTAGATTATTCTGGTAGATCAGTAATAGTTGTTGGTCCTAACTTAAAATTGCACCAATGTGGATTACCTAAGAAAATGG
CGTTAGAATTGTTTAAACCGTTTATTTGTTCAAAGTTAAAAATGTATGGTATTGTGCCAACAGTAAAATTGGCAAATAAA
ATGATACAAAATGAAAAGCCAGAAGTTTGGGATATCTTAGATGAAGTAATACATGAACATCCAATATTATTAAATAGAGC
ACCTACTTTGCATAGATTAGGTATACAAGCATTTGATCCAGTTTTGATAGAAGGTAAAGCAATACAATTACATCCTTTAG
TGTGTAGTGCTTTTAATGCTGATTTTGATGGTGACCAAATGGCAGTACATATTCCATTATCATTGGAAGCTCAACTTGAA
GCTAGGATATTAATGATGTCTACTAATAATATCTTAAGTCCTTCTAATGGTAAGCCAATAATTGTTCCTTCAAAGGACAT
AGTGCTTGGAATATATTACTTAACTTTACAAGATCAAGTTCAATCTGAAGATGAGATATTATTCTTTGGTGATTTTAGTC
ATGTGGAATACGCTTTACATAACAAAGATGTGCATTTATGTAGTCAAATTAAGTATAGAATGACTTATTGTAATTATGAT
ACATCGGATGGGAAGCCTTCATATTATTCTAAAATAATTGAAACAACTCCTGGTAGGTTGATATTATGGCAGATATTTCC
ACAACATAAAAATTTGACTTTTGATTTAATAAATCAAGTTTTAACTGTAAAAGAGATTACATCTATAGTTGATTTGGTAT
ATCGTAGTTGTGGTCAAAGTGAGACTGTTGAATTTTCAGATAAGTTGATGTCTCTTGGTTTTAAATATGCTTCGCAGTCT
GGTATTTCATTTGGATGTAAAGATATGATTATTCCAGATACAAAGACAATGCATGTAGATAATGCTAGTGAAAAAATCAA
AGAATTTGCTGTTCAATATCAAGATGGTTTAATTACAAGAAGTGAAAGATACAATAAAGTAATAGATGAATGGTCTAAGT
GTACTGACTTGATAGCTAAAGATATGATGAAAGCTATTTCTGTATATGATGTAGAAAGTAAATTAAATTCCATTTACATG
ATGGCTCATTCTGGTGCTAGAGGATCTGCATCACAGATGAAACAATTAGCAGGAATGAGAGGATTAATGGCTAAACCATC
AGGTGAAATTATTGAAACTCCTATAATATCTAATTTCCGTGAAGGGTTGAATGTATTTGAATATTTCAATTCGACTCACG
GAGCAAGAAAAGGTTTAGCAGATACCGCTTTGAAAACTGCGAATTCCGGATATTTAACTCGTAGGCTTGTTGATGTTGCT
CAGGATTGTATAGTTGTTGAGTACGATTGTAAAACACACAATGGATTTGCAATAAGGTCTGTTGTTGAAGGTGGGACTGT
AGTTGAAACATTAGATAATATAATACTTGGAAGAGTTGCTGCTGTTGATGTTTATAATCCTATTACTGAAGAGTTACTTG
TTAAAGCTGGAGAGTTAATAGATGAAGCTAAAGTTGAAAAAATAAAAATAGCAGGATTAGATGCTGTAAAAGTGAGATCT
CCTCTTACTTGTGAAGCGAAGAAAGGTATTTGTGCTTTGTGCTATGGTAGAGATCTTGCTATTGGTGATGTTGTATCAAT
AGGTGAAGCTGTTGGTGTAATAGCAGCTCAGTCTGTTGGTGAACCTGGAACACAGTTGACTATGCGTACTTTCCATGTAG
GTGGTACTGCAATGAGAGGTGTTGAAACTTCAAACTTAATAGCGTTATTAGATGCTAAGGTAAAGTTAGTAAACAGTAAT
ATCGTTGAAGACAAGCATGGTAATAAGATTGTCATGAGTAGATCTTGTGAAGTAGTGTTACTTGATAGTGTAGGCAATGA
AAAAATGCGTCATAATGTACCTTATGGAGCAAGACTTTATGTTGATGATGGTCAGTTAGTAAAAATTACAGAAAAAATTG
CTGAGTGGGATCCATATACAATGCCTATTATTACAGAAAAAACAGGTATCATTAAGTATATGGATTTAATAGATGGTGTG
TCTATCAATGAAGTCTTGGATGAATCTACTGGTATTTCTAACAGAGTAGTAGTTGATTGGAAATTACATTTACAGGGTGC
TAACCTCAGACCTAGGTTAGTTCTAATTGATGATAATGATAATATAATAACATTATCCAATGGTTTGGAGGCAAATTATT
TCATACCAATAGGGGCAGTGTTAAATGTTCAGGATGGACAAAAAGTTCATGCTGGAGATGTAATAACAAGAATTCCAAGA
GATTCTATAAAAACTAGAGATATTACAGGGGGGTTACCAAGAGTAATTGAATTGTTTGAAGCACGTCGTCCAAAAGAACA
TGCTATAGTAAGTGATATTGATGGTTATGTTGAATTTGGAAAAGATTATTATAGATCTAAAAGACGTATATTTATTAAGC
CAGTCAGTGATACCTTATCACCTGTTGAGTATTTAGTACCTAAAGGTAAGCATACTATTGTAAATGAGGGAGATTTTGTA
CATAAAGGGGATTTATTAATGGATGGTGATCCTGATCCTCATGATATATTACGTGTTTTAGGAGTTGAAGCATTAGCAAA
TTATATGATTTCTGAAATTCAGCAGGTTTATAGGTTACAGGGTGTGCGTATTGATAATAAACACATAGAAATAATCTTAA
GACAAATGTTGCAAAAAGTTGAAATATTTGAACCAGGAGACACTATGTATTTGGTTGGTGAAAATATAGACATGGAAGAA
GTAATAAAGACTAATGATAATATGGTAAAAATGGGTAAATCTCCTGCTAAATATGCTCCAATACTTCAAGGTATTACTAG
AGCGAGTCTTGATACTAACTCATTTGTTTCTGCAGCGTCATTCCAGGAAACAACAAAAGTATTAACAGAAGCAGCCTTTT
CTGGTAAGGAAGACTCTTTATATGGGTTAAAAGAGAATGTAATAGTAGGTCGATTAATACCTGCAGGTACAGGGTTCTTA
ATGAATAAGATAAAGAAGTTGTCTTTATTAAATAAAGAGGACTATTCTATGTATTATAATAATGAATATCAAGATTCAGC
ATTACTCCAAAATGATAATAATGCTTTTAACCAGGAACTGCATAAAGATACTGGAAATATTGTTGATTATTAA

Upstream 100 bases:

>100_bases
GTAAAAGAGTTAAGATCATTGTGTTTAGATGTTGCTTTAAAGCAAGATAAGGATTTCTTAAGTAATGAAGTGAAAGATTA
ATAATTAAAGGTAGTAGTAT

Downstream 100 bases:

>100_bases
AGCATCTAAGTCTTAATTATTGATGGGTGGAGAGGTGGTTCTTCTTCTTGTGAAGAGATGTAAATTATATGGTAGTGTTT
CTTTCTGTTTGTGGGTGCAT

Product: DNA-directed RNA polymerase, beta' subunit

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1410; Mature: 1410

Protein sequence:

>1410_residues
MKMLDLYGYTSIAQSFDKICISIASPESIRAMSYGEIKDISTTNYRTFKVEKGGLFCPKIFGPVNDDECLCGKYRKKRYR
GVVCEKCGVEVTSSKVRRERMGHIELVSPVAHVWFLKSLPSRIGALLDMPLKLIENILYSGDFVVIDPIATPLSKGEVIS
ESAYNQAKDNYGEDSFLALTGAEAIRELLVRLDLHAINANLRVELESTTSEMKRKKIVKRLRIVENFINSGNKPEWMILT
VIPILPPDLRPLVSLENGRPAVSDLNHHYRTIINRNNRLGKLLKLNPPAIMIRNEKRMLQEAVDALFDSTRRSYVSNKAG
SVGYKKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPNLKLHQCGLPKKMALELFKPFICSKLKMYGIVPTVKLANK
MIQNEKPEVWDILDEVIHEHPILLNRAPTLHRLGIQAFDPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHIPLSLEAQLE
ARILMMSTNNILSPSNGKPIIVPSKDIVLGIYYLTLQDQVQSEDEILFFGDFSHVEYALHNKDVHLCSQIKYRMTYCNYD
TSDGKPSYYSKIIETTPGRLILWQIFPQHKNLTFDLINQVLTVKEITSIVDLVYRSCGQSETVEFSDKLMSLGFKYASQS
GISFGCKDMIIPDTKTMHVDNASEKIKEFAVQYQDGLITRSERYNKVIDEWSKCTDLIAKDMMKAISVYDVESKLNSIYM
MAHSGARGSASQMKQLAGMRGLMAKPSGEIIETPIISNFREGLNVFEYFNSTHGARKGLADTALKTANSGYLTRRLVDVA
QDCIVVEYDCKTHNGFAIRSVVEGGTVVETLDNIILGRVAAVDVYNPITEELLVKAGELIDEAKVEKIKIAGLDAVKVRS
PLTCEAKKGICALCYGRDLAIGDVVSIGEAVGVIAAQSVGEPGTQLTMRTFHVGGTAMRGVETSNLIALLDAKVKLVNSN
IVEDKHGNKIVMSRSCEVVLLDSVGNEKMRHNVPYGARLYVDDGQLVKITEKIAEWDPYTMPIITEKTGIIKYMDLIDGV
SINEVLDESTGISNRVVVDWKLHLQGANLRPRLVLIDDNDNIITLSNGLEANYFIPIGAVLNVQDGQKVHAGDVITRIPR
DSIKTRDITGGLPRVIELFEARRPKEHAIVSDIDGYVEFGKDYYRSKRRIFIKPVSDTLSPVEYLVPKGKHTIVNEGDFV
HKGDLLMDGDPDPHDILRVLGVEALANYMISEIQQVYRLQGVRIDNKHIEIILRQMLQKVEIFEPGDTMYLVGENIDMEE
VIKTNDNMVKMGKSPAKYAPILQGITRASLDTNSFVSAASFQETTKVLTEAAFSGKEDSLYGLKENVIVGRLIPAGTGFL
MNKIKKLSLLNKEDYSMYYNNEYQDSALLQNDNNAFNQELHKDTGNIVDY

Sequences:

>Translated_1410_residues
MKMLDLYGYTSIAQSFDKICISIASPESIRAMSYGEIKDISTTNYRTFKVEKGGLFCPKIFGPVNDDECLCGKYRKKRYR
GVVCEKCGVEVTSSKVRRERMGHIELVSPVAHVWFLKSLPSRIGALLDMPLKLIENILYSGDFVVIDPIATPLSKGEVIS
ESAYNQAKDNYGEDSFLALTGAEAIRELLVRLDLHAINANLRVELESTTSEMKRKKIVKRLRIVENFINSGNKPEWMILT
VIPILPPDLRPLVSLENGRPAVSDLNHHYRTIINRNNRLGKLLKLNPPAIMIRNEKRMLQEAVDALFDSTRRSYVSNKAG
SVGYKKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPNLKLHQCGLPKKMALELFKPFICSKLKMYGIVPTVKLANK
MIQNEKPEVWDILDEVIHEHPILLNRAPTLHRLGIQAFDPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHIPLSLEAQLE
ARILMMSTNNILSPSNGKPIIVPSKDIVLGIYYLTLQDQVQSEDEILFFGDFSHVEYALHNKDVHLCSQIKYRMTYCNYD
TSDGKPSYYSKIIETTPGRLILWQIFPQHKNLTFDLINQVLTVKEITSIVDLVYRSCGQSETVEFSDKLMSLGFKYASQS
GISFGCKDMIIPDTKTMHVDNASEKIKEFAVQYQDGLITRSERYNKVIDEWSKCTDLIAKDMMKAISVYDVESKLNSIYM
MAHSGARGSASQMKQLAGMRGLMAKPSGEIIETPIISNFREGLNVFEYFNSTHGARKGLADTALKTANSGYLTRRLVDVA
QDCIVVEYDCKTHNGFAIRSVVEGGTVVETLDNIILGRVAAVDVYNPITEELLVKAGELIDEAKVEKIKIAGLDAVKVRS
PLTCEAKKGICALCYGRDLAIGDVVSIGEAVGVIAAQSVGEPGTQLTMRTFHVGGTAMRGVETSNLIALLDAKVKLVNSN
IVEDKHGNKIVMSRSCEVVLLDSVGNEKMRHNVPYGARLYVDDGQLVKITEKIAEWDPYTMPIITEKTGIIKYMDLIDGV
SINEVLDESTGISNRVVVDWKLHLQGANLRPRLVLIDDNDNIITLSNGLEANYFIPIGAVLNVQDGQKVHAGDVITRIPR
DSIKTRDITGGLPRVIELFEARRPKEHAIVSDIDGYVEFGKDYYRSKRRIFIKPVSDTLSPVEYLVPKGKHTIVNEGDFV
HKGDLLMDGDPDPHDILRVLGVEALANYMISEIQQVYRLQGVRIDNKHIEIILRQMLQKVEIFEPGDTMYLVGENIDMEE
VIKTNDNMVKMGKSPAKYAPILQGITRASLDTNSFVSAASFQETTKVLTEAAFSGKEDSLYGLKENVIVGRLIPAGTGFL
MNKIKKLSLLNKEDYSMYYNNEYQDSALLQNDNNAFNQELHKDTGNIVDY
>Mature_1410_residues
MKMLDLYGYTSIAQSFDKICISIASPESIRAMSYGEIKDISTTNYRTFKVEKGGLFCPKIFGPVNDDECLCGKYRKKRYR
GVVCEKCGVEVTSSKVRRERMGHIELVSPVAHVWFLKSLPSRIGALLDMPLKLIENILYSGDFVVIDPIATPLSKGEVIS
ESAYNQAKDNYGEDSFLALTGAEAIRELLVRLDLHAINANLRVELESTTSEMKRKKIVKRLRIVENFINSGNKPEWMILT
VIPILPPDLRPLVSLENGRPAVSDLNHHYRTIINRNNRLGKLLKLNPPAIMIRNEKRMLQEAVDALFDSTRRSYVSNKAG
SVGYKKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPNLKLHQCGLPKKMALELFKPFICSKLKMYGIVPTVKLANK
MIQNEKPEVWDILDEVIHEHPILLNRAPTLHRLGIQAFDPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHIPLSLEAQLE
ARILMMSTNNILSPSNGKPIIVPSKDIVLGIYYLTLQDQVQSEDEILFFGDFSHVEYALHNKDVHLCSQIKYRMTYCNYD
TSDGKPSYYSKIIETTPGRLILWQIFPQHKNLTFDLINQVLTVKEITSIVDLVYRSCGQSETVEFSDKLMSLGFKYASQS
GISFGCKDMIIPDTKTMHVDNASEKIKEFAVQYQDGLITRSERYNKVIDEWSKCTDLIAKDMMKAISVYDVESKLNSIYM
MAHSGARGSASQMKQLAGMRGLMAKPSGEIIETPIISNFREGLNVFEYFNSTHGARKGLADTALKTANSGYLTRRLVDVA
QDCIVVEYDCKTHNGFAIRSVVEGGTVVETLDNIILGRVAAVDVYNPITEELLVKAGELIDEAKVEKIKIAGLDAVKVRS
PLTCEAKKGICALCYGRDLAIGDVVSIGEAVGVIAAQSVGEPGTQLTMRTFHVGGTAMRGVETSNLIALLDAKVKLVNSN
IVEDKHGNKIVMSRSCEVVLLDSVGNEKMRHNVPYGARLYVDDGQLVKITEKIAEWDPYTMPIITEKTGIIKYMDLIDGV
SINEVLDESTGISNRVVVDWKLHLQGANLRPRLVLIDDNDNIITLSNGLEANYFIPIGAVLNVQDGQKVHAGDVITRIPR
DSIKTRDITGGLPRVIELFEARRPKEHAIVSDIDGYVEFGKDYYRSKRRIFIKPVSDTLSPVEYLVPKGKHTIVNEGDFV
HKGDLLMDGDPDPHDILRVLGVEALANYMISEIQQVYRLQGVRIDNKHIEIILRQMLQKVEIFEPGDTMYLVGENIDMEE
VIKTNDNMVKMGKSPAKYAPILQGITRASLDTNSFVSAASFQETTKVLTEAAFSGKEDSLYGLKENVIVGRLIPAGTGFL
MNKIKKLSLLNKEDYSMYYNNEYQDSALLQNDNNAFNQELHKDTGNIVDY

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=923, Percent_Identity=24.5937161430119, Blast_Score=173, Evalue=1e-42,
Organism=Homo sapiens, GI39725938, Length=315, Percent_Identity=32.0634920634921, Blast_Score=137, Evalue=7e-32,
Organism=Homo sapiens, GI103471997, Length=240, Percent_Identity=31.25, Blast_Score=97, Evalue=1e-19,
Organism=Escherichia coli, GI2367335, Length=1371, Percent_Identity=55.3610503282276, Blast_Score=1492, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=688, Percent_Identity=27.1802325581395, Blast_Score=179, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI71987878, Length=912, Percent_Identity=23.3552631578947, Blast_Score=167, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6320061, Length=908, Percent_Identity=24.6696035242291, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6324690, Length=566, Percent_Identity=25.6183745583039, Blast_Score=158, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6324917, Length=259, Percent_Identity=27.7992277992278, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI17530899, Length=908, Percent_Identity=23.1277533039648, Blast_Score=167, Evalue=5e-41,
Organism=Drosophila melanogaster, GI281360912, Length=727, Percent_Identity=24.7592847317744, Blast_Score=141, Evalue=3e-33,
Organism=Drosophila melanogaster, GI17647875, Length=235, Percent_Identity=28.936170212766, Blast_Score=94, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 157692; Mature: 157692

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMLDLYGYTSIAQSFDKICISIASPESIRAMSYGEIKDISTTNYRTFKVEKGGLFCPKI
CCEEECCCHHHHHHHHHHHEEEECCCCCEEECCCCCCCCCCCCCEEEEEEECCCEECHHH
FGPVNDDECLCGKYRKKRYRGVVCEKCGVEVTSSKVRRERMGHIELVSPVAHVWFLKSLP
CCCCCCCCHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHH
SRIGALLDMPLKLIENILYSGDFVVIDPIATPLSKGEVISESAYNQAKDNYGEDSFLALT
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEE
GAEAIRELLVRLDLHAINANLRVELESTTSEMKRKKIVKRLRIVENFINSGNKPEWMILT
CHHHHHHHHHHHHHEEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VIPILPPDLRPLVSLENGRPAVSDLNHHYRTIINRNNRLGKLLKLNPPAIMIRNEKRMLQ
EECCCCCCCCHHEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEECHHHHHH
EAVDALFDSTRRSYVSNKAGSVGYKKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGP
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECC
NLKLHQCGLPKKMALELFKPFICSKLKMYGIVPTVKLANKMIQNEKPEVWDILDEVIHEH
CCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHC
PILLNRAPTLHRLGIQAFDPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHIPLSLEAQLE
CEEECCCCCHHHCCHHHCCCEEEECCEEEEEHHHHHHCCCCCCCCEEEEEEECEEECCEE
ARILMMSTNNILSPSNGKPIIVPSKDIVLGIYYLTLQDQVQSEDEILFFGDFSHVEYALH
EEEEEEECCCEECCCCCCEEEECCCCEEEEEEEEEEEHHCCCCCCEEEEECCCCEEEECC
NKDVHLCSQIKYRMTYCNYDTSDGKPSYYSKIIETTPGRLILWQIFPQHKNLTFDLINQV
CCCHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHH
LTVKEITSIVDLVYRSCGQSETVEFSDKLMSLGFKYASQSGISFGCKDMIIPDTKTMHVD
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEC
NASEKIKEFAVQYQDGLITRSERYNKVIDEWSKCTDLIAKDMMKAISVYDVESKLNSIYM
CHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
MAHSGARGSASQMKQLAGMRGLMAKPSGEIIETPIISNFREGLNVFEYFNSTHGARKGLA
EEECCCCCCHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCHHHCCHH
DTALKTANSGYLTRRLVDVAQDCIVVEYDCKTHNGFAIRSVVEGGTVVETLDNIILGRVA
HHHHHCCCCCHHHHHHHHHHCCEEEEEECCCCCCCEEEEHHHCCCHHHHHHHHHHHHHHH
AVDVYNPITEELLVKAGELIDEAKVEKIKIAGLDAVKVRSPLTCEAKKGICALCYGRDLA
EEHHCCHHHHHHHHHHHHHHHHHHHCEEEEECCCEEECCCCCCCCCCCCEEEEEECCCCC
IGDVVSIGEAVGVIAAQSVGEPGTQLTMRTFHVGGTAMRGVETSNLIALLDAKVKLVNSN
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHCCCCCCCCEEEEEECEEEEECCC
IVEDKHGNKIVMSRSCEVVLLDSVGNEKMRHNVPYGARLYVDDGQLVKITEKIAEWDPYT
CCCCCCCCEEEEECCCCEEEEECCCCHHHHCCCCCCEEEEECCCCEEHHHHHHHCCCCCE
MPIITEKTGIIKYMDLIDGVSINEVLDESTGISNRVVVDWKLHLQGANLRPRLVLIDDND
EEEEECCCCHHHHHHHHCCCCHHHHHHHCCCCCCEEEEEEEEEEECCCCCCEEEEEECCC
NIITLSNGLEANYFIPIGAVLNVQDGQKVHAGDVITRIPRDSIKTRDITGGLPRVIELFE
CEEEEECCCCCEEEEEECEEEECCCCCEECCCHHHHHCCCCCCCCCCCCCCHHHHHHHHH
ARRPKEHAIVSDIDGYVEFGKDYYRSKRRIFIKPVSDTLSPVEYLVPKGKHTIVNEGDFV
CCCCCHHHHHHHHHHHHHHCHHHHCCCCEEEEEECCCHHCHHHHHCCCCCEEEECCCCEE
HKGDLLMDGDPDPHDILRVLGVEALANYMISEIQQVYRLQGVRIDNKHIEIILRQMLQKV
ECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHC
EIFEPGDTMYLVGENIDMEEVIKTNDNMVKMGKSPAKYAPILQGITRASLDTNSFVSAAS
CEECCCCEEEEEECCCCHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
FQETTKVLTEAAFSGKEDSLYGLKENVIVGRLIPAGTGFLMNKIKKLSLLNKEDYSMYYN
HHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEC
NEYQDSALLQNDNNAFNQELHKDTGNIVDY
CCCCCCHHEECCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKMLDLYGYTSIAQSFDKICISIASPESIRAMSYGEIKDISTTNYRTFKVEKGGLFCPKI
CCEEECCCHHHHHHHHHHHEEEECCCCCEEECCCCCCCCCCCCCEEEEEEECCCEECHHH
FGPVNDDECLCGKYRKKRYRGVVCEKCGVEVTSSKVRRERMGHIELVSPVAHVWFLKSLP
CCCCCCCCHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHH
SRIGALLDMPLKLIENILYSGDFVVIDPIATPLSKGEVISESAYNQAKDNYGEDSFLALT
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEE
GAEAIRELLVRLDLHAINANLRVELESTTSEMKRKKIVKRLRIVENFINSGNKPEWMILT
CHHHHHHHHHHHHHEEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VIPILPPDLRPLVSLENGRPAVSDLNHHYRTIINRNNRLGKLLKLNPPAIMIRNEKRMLQ
EECCCCCCCCHHEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEECHHHHHH
EAVDALFDSTRRSYVSNKAGSVGYKKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGP
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECC
NLKLHQCGLPKKMALELFKPFICSKLKMYGIVPTVKLANKMIQNEKPEVWDILDEVIHEH
CCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHC
PILLNRAPTLHRLGIQAFDPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHIPLSLEAQLE
CEEECCCCCHHHCCHHHCCCEEEECCEEEEEHHHHHHCCCCCCCCEEEEEEECEEECCEE
ARILMMSTNNILSPSNGKPIIVPSKDIVLGIYYLTLQDQVQSEDEILFFGDFSHVEYALH
EEEEEEECCCEECCCCCCEEEECCCCEEEEEEEEEEEHHCCCCCCEEEEECCCCEEEECC
NKDVHLCSQIKYRMTYCNYDTSDGKPSYYSKIIETTPGRLILWQIFPQHKNLTFDLINQV
CCCHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHH
LTVKEITSIVDLVYRSCGQSETVEFSDKLMSLGFKYASQSGISFGCKDMIIPDTKTMHVD
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEC
NASEKIKEFAVQYQDGLITRSERYNKVIDEWSKCTDLIAKDMMKAISVYDVESKLNSIYM
CHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
MAHSGARGSASQMKQLAGMRGLMAKPSGEIIETPIISNFREGLNVFEYFNSTHGARKGLA
EEECCCCCCHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCHHHCCHH
DTALKTANSGYLTRRLVDVAQDCIVVEYDCKTHNGFAIRSVVEGGTVVETLDNIILGRVA
HHHHHCCCCCHHHHHHHHHHCCEEEEEECCCCCCCEEEEHHHCCCHHHHHHHHHHHHHHH
AVDVYNPITEELLVKAGELIDEAKVEKIKIAGLDAVKVRSPLTCEAKKGICALCYGRDLA
EEHHCCHHHHHHHHHHHHHHHHHHHCEEEEECCCEEECCCCCCCCCCCCEEEEEECCCCC
IGDVVSIGEAVGVIAAQSVGEPGTQLTMRTFHVGGTAMRGVETSNLIALLDAKVKLVNSN
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHCCCCCCCCEEEEEECEEEEECCC
IVEDKHGNKIVMSRSCEVVLLDSVGNEKMRHNVPYGARLYVDDGQLVKITEKIAEWDPYT
CCCCCCCCEEEEECCCCEEEEECCCCHHHHCCCCCCEEEEECCCCEEHHHHHHHCCCCCE
MPIITEKTGIIKYMDLIDGVSINEVLDESTGISNRVVVDWKLHLQGANLRPRLVLIDDND
EEEEECCCCHHHHHHHHCCCCHHHHHHHCCCCCCEEEEEEEEEEECCCCCCEEEEEECCC
NIITLSNGLEANYFIPIGAVLNVQDGQKVHAGDVITRIPRDSIKTRDITGGLPRVIELFE
CEEEEECCCCCEEEEEECEEEECCCCCEECCCHHHHHCCCCCCCCCCCCCCHHHHHHHHH
ARRPKEHAIVSDIDGYVEFGKDYYRSKRRIFIKPVSDTLSPVEYLVPKGKHTIVNEGDFV
CCCCCHHHHHHHHHHHHHHCHHHHCCCCEEEEEECCCHHCHHHHHCCCCCEEEECCCCEE
HKGDLLMDGDPDPHDILRVLGVEALANYMISEIQQVYRLQGVRIDNKHIEIILRQMLQKV
ECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHC
EIFEPGDTMYLVGENIDMEEVIKTNDNMVKMGKSPAKYAPILQGITRASLDTNSFVSAAS
CEECCCCEEEEEECCCCHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
FQETTKVLTEAAFSGKEDSLYGLKENVIVGRLIPAGTGFLMNKIKKLSLLNKEDYSMYYN
HHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEC
NEYQDSALLQNDNNAFNQELHKDTGNIVDY
CCCCCCHHEECCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA