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The map label for this gene is xerC [H]

Identifier: 88607829

GI number: 88607829

Start: 197660

End: 198619

Strand: Direct

Name: xerC [H]

Synonym: APH_0200

Alternate gene names: 88607829

Gene position: 197660-198619 (Clockwise)

Preceding gene: 88607640

Following gene: 88607930

Centisome position: 13.43

GC content: 42.5

Gene sequence:

>960_bases
TTGCAGAATGGGGTGAGGATTGTTGTGGCTGTGACAAACTTATATGACGTTGTTGATGCTTGGGTTAAGTGTTTAGAAGA
GGAAAAAAGGTACTCCAAGCATACGGTAGCAGCATATTTAAGGGATATACGGGATTTTCTCCAGGTTGTGTATGGTCTAA
GACAGGAGAAGAGCGTTGTGCTGATTACAGAGATGGAAAACCTTCCCATGACGGAGTTTAGACGGTGGATTACTATACGC
TGCAACCAGGGAAAGCAGTCAGTATCTAATTTGCGTGCTATTTCGGCTATACGGAATTTTTTCCGCTATTTGCAAAGGAA
CCACGGTATTAAAAACGACGTTGTATTCCATATTGTAAACCCCATAGTACGCAAGGGCTTACCAAAGGTTTTGGAAAAGT
CACATGTACTCAAGATGGTTAGTGAAAATATCCATTGGACATCGCGAAGGGACGCCGCAATTGTTGCCTTACTGTACGGT
TGTGGCTTAAGAATAAGTGAAGCTGTGGGATTGCGATTTGGTGATCTAGAAGCTGATGCAGTACGTGTATTGGGTAAGGG
GAAGAAGGAGAGAATAATTCCTATCTTGCCCTGGGTGCAAAAGTTATTAGACGGGTATGTAGAGAGTTGCCCATTTCATG
GTACGGGGTGCGGAAATAAGGCATCATATGTATTTTTAGGGGTGCGTGGTAAAGTGCTTGATAGAACATACTTTGCACAT
AGAATGCAGGCATTACGTAGAAATATGGGTTTGCCTGAGAGTACAACACCCCATGCACTGCGACATAGCTTTGCTACTCA
CTTGTTTTTAGAAGGCGCAGACATCAGAGTGATTCAAGAGCTACTTGGTCATGAAAACCTATCGACTACGCAGATATACA
CGCACTTAGATCATAAGAGTATAATAGACAATTACATGGGATTTCATCCGCAAACTGTAAAAAAGAACAGTTCCGCATAA

Upstream 100 bases:

>100_bases
GTTCCATGAACAGCGTATGTATAATTGAAATATTGTGAAGTCAAAACTGACTAACCAATACAAAAGCCTATGACACAGTG
AGTATATAGCATAGCATCCT

Downstream 100 bases:

>100_bases
CTGCTATCAACCATTCGATAGTTTTGACTAAGACCAGCCACTGTGGTTTTTTCTTCAGGAGTGAGTTCTCCTTGACTAGG
TCTTTAGCTACAGCTATAGC

Product: tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MQNGVRIVVAVTNLYDVVDAWVKCLEEEKRYSKHTVAAYLRDIRDFLQVVYGLRQEKSVVLITEMENLPMTEFRRWITIR
CNQGKQSVSNLRAISAIRNFFRYLQRNHGIKNDVVFHIVNPIVRKGLPKVLEKSHVLKMVSENIHWTSRRDAAIVALLYG
CGLRISEAVGLRFGDLEADAVRVLGKGKKERIIPILPWVQKLLDGYVESCPFHGTGCGNKASYVFLGVRGKVLDRTYFAH
RMQALRRNMGLPESTTPHALRHSFATHLFLEGADIRVIQELLGHENLSTTQIYTHLDHKSIIDNYMGFHPQTVKKNSSA

Sequences:

>Translated_319_residues
MQNGVRIVVAVTNLYDVVDAWVKCLEEEKRYSKHTVAAYLRDIRDFLQVVYGLRQEKSVVLITEMENLPMTEFRRWITIR
CNQGKQSVSNLRAISAIRNFFRYLQRNHGIKNDVVFHIVNPIVRKGLPKVLEKSHVLKMVSENIHWTSRRDAAIVALLYG
CGLRISEAVGLRFGDLEADAVRVLGKGKKERIIPILPWVQKLLDGYVESCPFHGTGCGNKASYVFLGVRGKVLDRTYFAH
RMQALRRNMGLPESTTPHALRHSFATHLFLEGADIRVIQELLGHENLSTTQIYTHLDHKSIIDNYMGFHPQTVKKNSSA
>Mature_319_residues
MQNGVRIVVAVTNLYDVVDAWVKCLEEEKRYSKHTVAAYLRDIRDFLQVVYGLRQEKSVVLITEMENLPMTEFRRWITIR
CNQGKQSVSNLRAISAIRNFFRYLQRNHGIKNDVVFHIVNPIVRKGLPKVLEKSHVLKMVSENIHWTSRRDAAIVALLYG
CGLRISEAVGLRFGDLEADAVRVLGKGKKERIIPILPWVQKLLDGYVESCPFHGTGCGNKASYVFLGVRGKVLDRTYFAH
RMQALRRNMGLPESTTPHALRHSFATHLFLEGADIRVIQELLGHENLSTTQIYTHLDHKSIIDNYMGFHPQTVKKNSSA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=303, Percent_Identity=32.6732673267327, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1790244, Length=309, Percent_Identity=31.3915857605178, Blast_Score=135, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 36477; Mature: 36477

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNGVRIVVAVTNLYDVVDAWVKCLEEEKRYSKHTVAAYLRDIRDFLQVVYGLRQEKSVV
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
LITEMENLPMTEFRRWITIRCNQGKQSVSNLRAISAIRNFFRYLQRNHGIKNDVVFHIVN
EEEECCCCCHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
PIVRKGLPKVLEKSHVLKMVSENIHWTSRRDAAIVALLYGCGLRISEAVGLRFGDLEADA
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCCCHHH
VRVLGKGKKERIIPILPWVQKLLDGYVESCPFHGTGCGNKASYVFLGVRGKVLDRTYFAH
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHH
RMQALRRNMGLPESTTPHALRHSFATHLFLEGADIRVIQELLGHENLSTTQIYTHLDHKS
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHCCHHH
IIDNYMGFHPQTVKKNSSA
HHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MQNGVRIVVAVTNLYDVVDAWVKCLEEEKRYSKHTVAAYLRDIRDFLQVVYGLRQEKSVV
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
LITEMENLPMTEFRRWITIRCNQGKQSVSNLRAISAIRNFFRYLQRNHGIKNDVVFHIVN
EEEECCCCCHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
PIVRKGLPKVLEKSHVLKMVSENIHWTSRRDAAIVALLYGCGLRISEAVGLRFGDLEADA
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCCCHHH
VRVLGKGKKERIIPILPWVQKLLDGYVESCPFHGTGCGNKASYVFLGVRGKVLDRTYFAH
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHH
RMQALRRNMGLPESTTPHALRHSFATHLFLEGADIRVIQELLGHENLSTTQIYTHLDHKS
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHCCHHH
IIDNYMGFHPQTVKKNSSA
HHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]