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The map label for this gene is atpD

Identifier: 88607774

GI number: 88607774

Start: 521127

End: 522566

Strand: Reverse

Name: atpD

Synonym: APH_0494

Alternate gene names: 88607774

Gene position: 522566-521127 (Counterclockwise)

Preceding gene: 88607410

Following gene: 88607216

Centisome position: 35.52

GC content: 46.94

Gene sequence:

>1440_bases
GTGAATCAGGATTCTGGCTGCGAAGGTGTTGGAGAAGTTGTCAGGGTGATGCCTGCGGTCGTTGATGTTGAGTTTGCCCA
CGGAGGTCTGCCGGATATCTTACATGCTTTGAAAAGTGAAAAGGATTACCAAGGAAAGCAATTGGTTCTAGAAGTAGCAC
AGCACCTCGGGGATGGGGTTGTTAGATGCGTTGCCATGGGTAGCACCGATGGTCTATCTAGGGGGGATAAGTTTATCAAT
ACTGGCTCGCCCATTTCTGTTCCTGTGGGACGTAAAACATTGGGTAGGGTCTTTGATGTTTTAGGGGAGCCCATAGATGG
AGTTGGTGATGTAGGCGCAGATGTCGAATACCACTCTATACACGCTCATGCTCCGAAGTTATCAGAACAGAAGGTTGCTA
CTGAAGTCTTAGTGACAGGTATCAAGGTAATCGATTTATTGGCTCCGTATCTAAAAGGTGGAAAGGTCGGTCTGTTTGGT
GGGGCAGGTGTTGGAAAGACAGTCCTCATAATGGAGTTGATAAGCAATATAGCTAGGGCACATAAGGGTTTCTCCGTTTT
TGCGGGTGTCGGTGAGCGTACTCGTGAAGGTAATGACTTATATCGTGAGATGGTAGAGTCTGGGGTAATTAATGAAGATG
AGCGCGAAAAATCACAAGCGGTGCTTGTGTATGGGCAAATGAATGAGCCTCCTGGTGCCAGAATGAGGGTTGCGCTTTCG
GCATTGACCATGGCTGAGTATTTTCGTGATGCTGAAGGGCAAGACGTTTTGTTCTTTGTTGATAATGTATTTAGGTTTAC
GCAGTCTGGGTCAGAGGTTTCTGCGCTTCTCGGGCGTGTGCCATCTGCTGTGGGATATCAGCCGACGCTAGCTTCTGAAA
TGGGGGCAATGCAAGAGCGTATTACTTCTACTCACAAGGGGTCAATTACTTCCGTTCAGGCTATATACGTCCCTGCGGAT
GACTTGACAGATCCGGCTCCTTCTACTTCGTTCCTGCACCTTGATTCTACTACAGTGTTGTCTAGGCAGATTTCGGAGCT
TGGTATATACCCTGCAGTGGATCCTTTGGATTCAACTTCACAGGCGTTGTCTGTTGATGTGGTTGGTGCTGAGCACTATG
AGGTTGCTAGAGAGGTTCAACGTATTCTACAGACGTATAAGTCTCTTCAGGACATTATTGCGATACTTGGTATGGATGAG
TTGTCTCAGGAAGACAAGATATTGGTTGCTAGGGCTCGTAAAATTCAGAGATTTTTATCGCAGCCGTTCCATGTAGCGGA
AGTCTTCACTGGTAATCCTGGTGTTTTTGTATCATTAGAAGATACAGTGCGTAGTTTCAAGGGATTGGTAGAGGGGCAGT
ATGATGATCTGCCTGAAGCAGCGTTTTACATGGTTGGTGGTATAGATGCTGCCGTTGAGAAGGCGAAGGCTCTGAAATAG

Upstream 100 bases:

>100_bases
ATCTGGTTTTTAGCATGCCTACGGTGGGCTGTTTTTGTCGTGTGGATAACTCTTCTTGGTTAGGTGTAGAATGAAGAAAG
TCAAAAAGGAAGTTAGTAAG

Downstream 100 bases:

>100_bases
CTGTTTTTCTGAGAAAGGTTCGGGAGAATATGTCTGGGGGGTTGATCTACTTCGGTGTTGCGGCTTGTAATTGATGTGGT
GAGGATTATTCATGGATAGC

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MNQDSGCEGVGEVVRVMPAVVDVEFAHGGLPDILHALKSEKDYQGKQLVLEVAQHLGDGVVRCVAMGSTDGLSRGDKFIN
TGSPISVPVGRKTLGRVFDVLGEPIDGVGDVGADVEYHSIHAHAPKLSEQKVATEVLVTGIKVIDLLAPYLKGGKVGLFG
GAGVGKTVLIMELISNIARAHKGFSVFAGVGERTREGNDLYREMVESGVINEDEREKSQAVLVYGQMNEPPGARMRVALS
ALTMAEYFRDAEGQDVLFFVDNVFRFTQSGSEVSALLGRVPSAVGYQPTLASEMGAMQERITSTHKGSITSVQAIYVPAD
DLTDPAPSTSFLHLDSTTVLSRQISELGIYPAVDPLDSTSQALSVDVVGAEHYEVAREVQRILQTYKSLQDIIAILGMDE
LSQEDKILVARARKIQRFLSQPFHVAEVFTGNPGVFVSLEDTVRSFKGLVEGQYDDLPEAAFYMVGGIDAAVEKAKALK

Sequences:

>Translated_479_residues
MNQDSGCEGVGEVVRVMPAVVDVEFAHGGLPDILHALKSEKDYQGKQLVLEVAQHLGDGVVRCVAMGSTDGLSRGDKFIN
TGSPISVPVGRKTLGRVFDVLGEPIDGVGDVGADVEYHSIHAHAPKLSEQKVATEVLVTGIKVIDLLAPYLKGGKVGLFG
GAGVGKTVLIMELISNIARAHKGFSVFAGVGERTREGNDLYREMVESGVINEDEREKSQAVLVYGQMNEPPGARMRVALS
ALTMAEYFRDAEGQDVLFFVDNVFRFTQSGSEVSALLGRVPSAVGYQPTLASEMGAMQERITSTHKGSITSVQAIYVPAD
DLTDPAPSTSFLHLDSTTVLSRQISELGIYPAVDPLDSTSQALSVDVVGAEHYEVAREVQRILQTYKSLQDIIAILGMDE
LSQEDKILVARARKIQRFLSQPFHVAEVFTGNPGVFVSLEDTVRSFKGLVEGQYDDLPEAAFYMVGGIDAAVEKAKALK
>Mature_479_residues
MNQDSGCEGVGEVVRVMPAVVDVEFAHGGLPDILHALKSEKDYQGKQLVLEVAQHLGDGVVRCVAMGSTDGLSRGDKFIN
TGSPISVPVGRKTLGRVFDVLGEPIDGVGDVGADVEYHSIHAHAPKLSEQKVATEVLVTGIKVIDLLAPYLKGGKVGLFG
GAGVGKTVLIMELISNIARAHKGFSVFAGVGERTREGNDLYREMVESGVINEDEREKSQAVLVYGQMNEPPGARMRVALS
ALTMAEYFRDAEGQDVLFFVDNVFRFTQSGSEVSALLGRVPSAVGYQPTLASEMGAMQERITSTHKGSITSVQAIYVPAD
DLTDPAPSTSFLHLDSTTVLSRQISELGIYPAVDPLDSTSQALSVDVVGAEHYEVAREVQRILQTYKSLQDIIAILGMDE
LSQEDKILVARARKIQRFLSQPFHVAEVFTGNPGVFVSLEDTVRSFKGLVEGQYDDLPEAAFYMVGGIDAAVEKAKALK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=470, Percent_Identity=68.936170212766, Blast_Score=650, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=310, Percent_Identity=26.7741935483871, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI19913426, Length=429, Percent_Identity=24.4755244755245, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI19913428, Length=372, Percent_Identity=24.4623655913978, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI50345984, Length=404, Percent_Identity=24.7524752475248, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI4757810, Length=404, Percent_Identity=24.7524752475248, Blast_Score=90, Evalue=4e-18,
Organism=Escherichia coli, GI1790170, Length=468, Percent_Identity=66.2393162393162, Blast_Score=612, Evalue=1e-176,
Organism=Escherichia coli, GI1788251, Length=332, Percent_Identity=29.8192771084337, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790172, Length=325, Percent_Identity=26.7692307692308, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI25144756, Length=468, Percent_Identity=68.3760683760684, Blast_Score=643, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17565854, Length=313, Percent_Identity=26.8370607028754, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17510931, Length=357, Percent_Identity=23.249299719888, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71988080, Length=305, Percent_Identity=25.2459016393443, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17570191, Length=406, Percent_Identity=23.3990147783251, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71988063, Length=305, Percent_Identity=25.2459016393443, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71988074, Length=266, Percent_Identity=23.3082706766917, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322581, Length=462, Percent_Identity=69.6969696969697, Blast_Score=647, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=359, Percent_Identity=25.6267409470752, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319370, Length=384, Percent_Identity=25.78125, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320016, Length=236, Percent_Identity=25.8474576271186, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24638766, Length=468, Percent_Identity=69.017094017094, Blast_Score=649, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=463, Percent_Identity=66.7386609071274, Blast_Score=621, Evalue=1e-178,
Organism=Drosophila melanogaster, GI20129479, Length=300, Percent_Identity=26.6666666666667, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24583988, Length=310, Percent_Identity=26.7741935483871, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24583986, Length=310, Percent_Identity=26.7741935483871, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24583984, Length=310, Percent_Identity=26.7741935483871, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24583992, Length=310, Percent_Identity=26.1290322580645, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI281361666, Length=364, Percent_Identity=24.1758241758242, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24646341, Length=364, Percent_Identity=24.1758241758242, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17136796, Length=364, Percent_Identity=24.1758241758242, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24638768, Length=93, Percent_Identity=53.763440860215, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24658560, Length=305, Percent_Identity=25.5737704918033, Blast_Score=92, Evalue=1e-18,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB_ANAPZ (Q2GKK8)

Other databases:

- EMBL:   CP000235
- RefSeq:   YP_505093.1
- ProteinModelPortal:   Q2GKK8
- SMR:   Q2GKK8
- STRING:   Q2GKK8
- GeneID:   3930811
- GenomeReviews:   CP000235_GR
- KEGG:   aph:APH_0494
- NMPDR:   fig|212042.5.peg.489
- TIGR:   APH_0494
- eggNOG:   COG0055
- HOGENOM:   HBG565875
- OMA:   HYKTARA
- PhylomeDB:   Q2GKK8
- ProtClustDB:   PRK09280
- BioCyc:   APHA212042:APH_0494-MONOMER
- HAMAP:   MF_01347
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 51511; Mature: 51511

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQDSGCEGVGEVVRVMPAVVDVEFAHGGLPDILHALKSEKDYQGKQLVLEVAQHLGDGV
CCCCCCCHHHHHHHHHHHHHHEEEHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHH
VRCVAMGSTDGLSRGDKFINTGSPISVPVGRKTLGRVFDVLGEPIDGVGDVGADVEYHSI
EEHEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
HAHAPKLSEQKVATEVLVTGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIMELISNIARA
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHH
HKGFSVFAGVGERTREGNDLYREMVESGVINEDEREKSQAVLVYGQMNEPPGARMRVALS
HCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCHHCCCCEEEEEECCCCCCCHHHHHHHH
ALTMAEYFRDAEGQDVLFFVDNVFRFTQSGSEVSALLGRVPSAVGYQPTLASEMGAMQER
HHHHHHHHHCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHCCHHCCCCCHHHHHHHHHHHH
ITSTHKGSITSVQAIYVPADDLTDPAPSTSFLHLDSTTVLSRQISELGIYPAVDPLDSTS
HHHCCCCCCEEEEEEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCC
QALSVDVVGAEHYEVAREVQRILQTYKSLQDIIAILGMDELSQEDKILVARARKIQRFLS
CEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHC
QPFHVAEVFTGNPGVFVSLEDTVRSFKGLVEGQYDDLPEAAFYMVGGIDAAVEKAKALK
CCCEEEEEEECCCCEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure
MNQDSGCEGVGEVVRVMPAVVDVEFAHGGLPDILHALKSEKDYQGKQLVLEVAQHLGDGV
CCCCCCCHHHHHHHHHHHHHHEEEHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHH
VRCVAMGSTDGLSRGDKFINTGSPISVPVGRKTLGRVFDVLGEPIDGVGDVGADVEYHSI
EEHEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
HAHAPKLSEQKVATEVLVTGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIMELISNIARA
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHH
HKGFSVFAGVGERTREGNDLYREMVESGVINEDEREKSQAVLVYGQMNEPPGARMRVALS
HCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCHHCCCCEEEEEECCCCCCCHHHHHHHH
ALTMAEYFRDAEGQDVLFFVDNVFRFTQSGSEVSALLGRVPSAVGYQPTLASEMGAMQER
HHHHHHHHHCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHCCHHCCCCCHHHHHHHHHHHH
ITSTHKGSITSVQAIYVPADDLTDPAPSTSFLHLDSTTVLSRQISELGIYPAVDPLDSTS
HHHCCCCCCEEEEEEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCC
QALSVDVVGAEHYEVAREVQRILQTYKSLQDIIAILGMDELSQEDKILVARARKIQRFLS
CEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHC
QPFHVAEVFTGNPGVFVSLEDTVRSFKGLVEGQYDDLPEAAFYMVGGIDAAVEKAKALK
CCCEEEEEEECCCCEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA