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The map label for this gene is znuA [H]

Identifier: 88607687

GI number: 88607687

Start: 1040936

End: 1041796

Strand: Reverse

Name: znuA [H]

Synonym: APH_0982

Alternate gene names: 88607687

Gene position: 1041796-1040936 (Counterclockwise)

Preceding gene: 88607330

Following gene: 88606938

Centisome position: 70.81

GC content: 40.77

Gene sequence:

>861_bases
ATGCTGACCAGAATACATATTATTTCGCTATTGGTGGCACTTCTCCTGCCTACAGCAGGATATACCGTTCCCAAAGTGGC
TGCAACCATAAATCCAATACACTTCTTAGTAAGTGACGTAGGCCGCGGTGTAGTGAAGCCTTCGTTACCATCTATAGGTA
TGTCATGCGTGCATGACTATGTGCTGAAGCCTTCGGATGTGGCAAGCCTGAATGCAGCTGATATTGTCTTCTATGTAGAT
GAGAGTATGGAGCCTTATATTCAGAAGTTGGCAGACGGGCCTCAAAAAAAGCTTATTAGGCTCTCAGACGAAGTAGAACT
ACTATCGAATAGGGGGTACCACGGGAGTTATGAGGGGCAAAACACAAAGGATTTCCATATATGGTTAAATCCTGAGAATG
CTAAAAAAATAATTGGCAAAATATGCTCAACTTTATCTGAAGCAGATCCAGAAAATGCGGAGATTTATAAGAAGAATGCT
GAAAATGCTTTGGAGAAAATCTCTGCTATGACAGAGGATATCCATGAGATGCTAGCATCAGTAAAGAGTGTACCTTACAT
AGTTGCACATGATGCATATCAATATTTTGATCGCTATTTTGGGCTGCACTGTGTTGCTTCGTTATCATCGGGGCATATAA
CAGCAAAAGAGCTATTTTTGGCGCGAGCTGCAGCGAAGAAGCATGGAGTGAAATGCATTTTTACGGATATGTATAGCAAC
AAACAACGATATAAATTTATAAGTAAGAAGATAAAGATCCAAGCTGTAGATCCGATTGGCAGCTCAATTACTGTAGATGA
GGATGGGTACTATCAACTGATGCAAACTCTGGCAGAAGGATTCAAAAAGTGTCTAGAATAA

Upstream 100 bases:

>100_bases
TTACCTTCCTATTTCCATAGAACAAGGTTATACTGTCAACAACAAGCATGGGTAGAACACTCTTCTGAAGCCCCGCGACG
CGTGTGACAGGTTCCTTGAT

Downstream 100 bases:

>100_bases
CATGTTTAATTGAGCGGCTAGTTGTGTGAGATTTATATAAGATTTTCTGATCTTGAAGATGATAGGATGCATGTTTGGTC
TGTAATATTACAGCTTCTAA

Product: putative cation ABC transporter, periplasmic cation-binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MLTRIHIISLLVALLLPTAGYTVPKVAATINPIHFLVSDVGRGVVKPSLPSIGMSCVHDYVLKPSDVASLNAADIVFYVD
ESMEPYIQKLADGPQKKLIRLSDEVELLSNRGYHGSYEGQNTKDFHIWLNPENAKKIIGKICSTLSEADPENAEIYKKNA
ENALEKISAMTEDIHEMLASVKSVPYIVAHDAYQYFDRYFGLHCVASLSSGHITAKELFLARAAAKKHGVKCIFTDMYSN
KQRYKFISKKIKIQAVDPIGSSITVDEDGYYQLMQTLAEGFKKCLE

Sequences:

>Translated_286_residues
MLTRIHIISLLVALLLPTAGYTVPKVAATINPIHFLVSDVGRGVVKPSLPSIGMSCVHDYVLKPSDVASLNAADIVFYVD
ESMEPYIQKLADGPQKKLIRLSDEVELLSNRGYHGSYEGQNTKDFHIWLNPENAKKIIGKICSTLSEADPENAEIYKKNA
ENALEKISAMTEDIHEMLASVKSVPYIVAHDAYQYFDRYFGLHCVASLSSGHITAKELFLARAAAKKHGVKCIFTDMYSN
KQRYKFISKKIKIQAVDPIGSSITVDEDGYYQLMQTLAEGFKKCLE
>Mature_286_residues
MLTRIHIISLLVALLLPTAGYTVPKVAATINPIHFLVSDVGRGVVKPSLPSIGMSCVHDYVLKPSDVASLNAADIVFYVD
ESMEPYIQKLADGPQKKLIRLSDEVELLSNRGYHGSYEGQNTKDFHIWLNPENAKKIIGKICSTLSEADPENAEIYKKNA
ENALEKISAMTEDIHEMLASVKSVPYIVAHDAYQYFDRYFGLHCVASLSSGHITAKELFLARAAAKKHGVKCIFTDMYSN
KQRYKFISKKIKIQAVDPIGSSITVDEDGYYQLMQTLAEGFKKCLE

Specific function: Involved in the high-affinity zinc uptake transport system. Required for survival and normal growth under low Zn (2+) concentrations. Also required for virulence and intracellular growth in macrophages [H]

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=287, Percent_Identity=27.1777003484321, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 31836; Mature: 31836

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTRIHIISLLVALLLPTAGYTVPKVAATINPIHFLVSDVGRGVVKPSLPSIGMSCVHDY
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
VLKPSDVASLNAADIVFYVDESMEPYIQKLADGPQKKLIRLSDEVELLSNRGYHGSYEGQ
HCCCCCCCCCCCCEEEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
NTKDFHIWLNPENAKKIIGKICSTLSEADPENAEIYKKNAENALEKISAMTEDIHEMLAS
CCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKSVPYIVAHDAYQYFDRYFGLHCVASLSSGHITAKELFLARAAAKKHGVKCIFTDMYSN
HHHCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEHHHCC
KQRYKFISKKIKIQAVDPIGSSITVDEDGYYQLMQTLAEGFKKCLE
HHHHHHHHHHEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTRIHIISLLVALLLPTAGYTVPKVAATINPIHFLVSDVGRGVVKPSLPSIGMSCVHDY
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
VLKPSDVASLNAADIVFYVDESMEPYIQKLADGPQKKLIRLSDEVELLSNRGYHGSYEGQ
HCCCCCCCCCCCCEEEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
NTKDFHIWLNPENAKKIIGKICSTLSEADPENAEIYKKNAENALEKISAMTEDIHEMLAS
CCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKSVPYIVAHDAYQYFDRYFGLHCVASLSSGHITAKELFLARAAAKKHGVKCIFTDMYSN
HHHCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEHHHCC
KQRYKFISKKIKIQAVDPIGSSITVDEDGYYQLMQTLAEGFKKCLE
HHHHHHHHHHEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA