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The map label for this gene is xerD [H]

Identifier: 88607245

GI number: 88607245

Start: 36738

End: 37673

Strand: Direct

Name: xerD [H]

Synonym: APH_0040

Alternate gene names: 88607245

Gene position: 36738-37673 (Clockwise)

Preceding gene: 88607630

Following gene: 88607511

Centisome position: 2.5

GC content: 41.88

Gene sequence:

>936_bases
GTGGGTGATGACTACATAATACGTTCGTTTCTGGAGTTTCTTGTTTCTAGCAAGGGGGTATCTGAGAATACGGTCTGTAG
TTACAAATGTGATCTCGAAGATTTAAGTCAGTTTTTAAGGCGTAATGGGTTAAAAATTGTTGATGCTAGCTATGGTGACC
TATGTGAGTATATACGAAACCTAAACGGAAGAGCTTACAGTGCTGCTACCGTTGCCAGAAGAGTATCAGCAATTAAAGGA
TTGTGTAGCTTTCTATACAAGGATCGCATTGTTCATAGTGATTTGTCGCTCAGTCTGGAATCTTGTAGGTTAGGTCGCAC
TTTGCCCAGGGTGATAAGTGAGTCAGATATTGGCATGTTATTAGATATTGCCAAGGCAGACCTTTCAGCAGAGGGGAAGC
GCTTATATGCCATTGTAAATATATTATACTCATCTGGGGTAAGAATATCGGAACTTATACATTTGGGCTTTTTCGAAATT
GATGCGATGTTGCATGAGCACGTAGGCGATATCGGGTACATTATCATAAAAGGCAAGGGGAACCGTGAGAGACTTGTGCT
ACTCAATGAGGTGGCTATGGATAGCATAAGAGCCTACCTAGAAGTTCGAAAATGCTTCATTGCAGGAGAGAATACGGAGT
CCAGGTGGTTATTTCCGGGGGCGAAGTATGATCAGTGTATTAGCAGGCAGAGAGTTGGGCAGTTATTGAAGGAACTTGCA
ATTTCTGCGGGAATAGATCCAGAAAAGGTTTCGCCACATAAGTTTAGGCATTCGTTCGCAACACATTTACTCAATAACGG
CTCTAATATAGTCTTTATACAGAAGATGCTCGGGCATGTTAATCTGTCTACCACACAGGTATATACGCACGTCGCTAGTG
AACAGCTAAGGGATGTGTTGAGTAGATTTCATCCTATGTCTAAATCCAAAAACTGA

Upstream 100 bases:

>100_bases
CTGTAGGGTAGTGGTTTGTTCATGAACTGTGCAATTTTGGGAATACCTAAATGTTATTTGTTAAGCTACATACGTTATTG
CGTTCAAGGTAGAGGCTCAA

Downstream 100 bases:

>100_bases
AATGTGTGTATGGCGAGGTGTCCAGAATTACGCTTCGCAGCTTAGAATTTTCTCAATTACCGTACTTGCTAGGTGATAAG
TTTTGAGATGCTGAATAAGT

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MGDDYIIRSFLEFLVSSKGVSENTVCSYKCDLEDLSQFLRRNGLKIVDASYGDLCEYIRNLNGRAYSAATVARRVSAIKG
LCSFLYKDRIVHSDLSLSLESCRLGRTLPRVISESDIGMLLDIAKADLSAEGKRLYAIVNILYSSGVRISELIHLGFFEI
DAMLHEHVGDIGYIIIKGKGNRERLVLLNEVAMDSIRAYLEVRKCFIAGENTESRWLFPGAKYDQCISRQRVGQLLKELA
ISAGIDPEKVSPHKFRHSFATHLLNNGSNIVFIQKMLGHVNLSTTQVYTHVASEQLRDVLSRFHPMSKSKN

Sequences:

>Translated_311_residues
MGDDYIIRSFLEFLVSSKGVSENTVCSYKCDLEDLSQFLRRNGLKIVDASYGDLCEYIRNLNGRAYSAATVARRVSAIKG
LCSFLYKDRIVHSDLSLSLESCRLGRTLPRVISESDIGMLLDIAKADLSAEGKRLYAIVNILYSSGVRISELIHLGFFEI
DAMLHEHVGDIGYIIIKGKGNRERLVLLNEVAMDSIRAYLEVRKCFIAGENTESRWLFPGAKYDQCISRQRVGQLLKELA
ISAGIDPEKVSPHKFRHSFATHLLNNGSNIVFIQKMLGHVNLSTTQVYTHVASEQLRDVLSRFHPMSKSKN
>Mature_310_residues
GDDYIIRSFLEFLVSSKGVSENTVCSYKCDLEDLSQFLRRNGLKIVDASYGDLCEYIRNLNGRAYSAATVARRVSAIKGL
CSFLYKDRIVHSDLSLSLESCRLGRTLPRVISESDIGMLLDIAKADLSAEGKRLYAIVNILYSSGVRISELIHLGFFEID
AMLHEHVGDIGYIIIKGKGNRERLVLLNEVAMDSIRAYLEVRKCFIAGENTESRWLFPGAKYDQCISRQRVGQLLKELAI
SAGIDPEKVSPHKFRHSFATHLLNNGSNIVFIQKMLGHVNLSTTQVYTHVASEQLRDVLSRFHPMSKSKN

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=300, Percent_Identity=37.6666666666667, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI1790244, Length=308, Percent_Identity=30.1948051948052, Blast_Score=133, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34969; Mature: 34838

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDDYIIRSFLEFLVSSKGVSENTVCSYKCDLEDLSQFLRRNGLKIVDASYGDLCEYIRN
CCCHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHCCCEEEECCHHHHHHHHHC
LNGRAYSAATVARRVSAIKGLCSFLYKDRIVHSDLSLSLESCRLGRTLPRVISESDIGML
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHCCCCCHHH
LDIAKADLSAEGKRLYAIVNILYSSGVRISELIHLGFFEIDAMLHEHVGDIGYIIIKGKG
HHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
NRERLVLLNEVAMDSIRAYLEVRKCFIAGENTESRWLFPGAKYDQCISRQRVGQLLKELA
CCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHH
ISAGIDPEKVSPHKFRHSFATHLLNNGSNIVFIQKMLGHVNLSTTQVYTHVASEQLRDVL
HHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHH
SRFHPMSKSKN
HHHCCCCCCCC
>Mature Secondary Structure 
GDDYIIRSFLEFLVSSKGVSENTVCSYKCDLEDLSQFLRRNGLKIVDASYGDLCEYIRN
CCHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHCCCEEEECCHHHHHHHHHC
LNGRAYSAATVARRVSAIKGLCSFLYKDRIVHSDLSLSLESCRLGRTLPRVISESDIGML
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHCCCCCHHH
LDIAKADLSAEGKRLYAIVNILYSSGVRISELIHLGFFEIDAMLHEHVGDIGYIIIKGKG
HHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
NRERLVLLNEVAMDSIRAYLEVRKCFIAGENTESRWLFPGAKYDQCISRQRVGQLLKELA
CCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHH
ISAGIDPEKVSPHKFRHSFATHLLNNGSNIVFIQKMLGHVNLSTTQVYTHVASEQLRDVL
HHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHH
SRFHPMSKSKN
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]