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The map label for this gene is nuoG [H]

Identifier: 88607242

GI number: 88607242

Start: 744321

End: 746399

Strand: Reverse

Name: nuoG [H]

Synonym: APH_0712

Alternate gene names: 88607242

Gene position: 746399-744321 (Counterclockwise)

Preceding gene: 88606700

Following gene: 88607453

Centisome position: 50.73

GC content: 44.16

Gene sequence:

>2079_bases
GTGGTTGAAGTTACTGTCAATTCTGTAAGCATCAATGTAGAAGATGGAATGACGGTTCTTCAGGCATGTGAGATTGCCGG
GGTAGAAATACCTAGATTTTGCTACCATGAGCGTTTGGCGATAGCCGGAAATTGTAGGATGTGTCTTGTGGAGATAGTGG
GGCAGCCGAAATTAGCGGCGTCGTGTGCTATGCCTATAGCAAATGGTATGGTAATCAATACAGATACTGAAAAGGTAAAA
AAGGCCAGAAAGGGAGTTCTAGAGCTGTTATTGGTCAATCATCCTTTAGATTGTCCTATATGCGATCAGGGTGGAGAGTG
TGATCTTCAAGACCAGGTGGTTGCCTATGGATGCGGAATAGGTAGGTATCACGAGGAAAAAAGAGCAGTATCCAAGAAGG
CTTTTGGTCCTCTTATAGAGAACTCTATGAATAGGTGCATTCACTGTACTAGGTGTGTGCGGTTTCTCTCAGACGTTGCC
GGAACTTACGAATTTGGTACTTTCGGTAGGGGGGAGAAGATGGAGATAGATACTTGCGTTGAGCAAGGGGTCACTTCTGA
GTTATCGGGAAACATAATTGATTTATGCCCAGTGGGGGCATTAACGTCGAAGCCATACGCGTTTAAAGCCAGGCCTTGGG
AGTTGTATCACTGTGATACGATAGATGTGATGGATGCCGTAGGTTGTAGTATACGGGTGGATTGTAGAGGTCTCAATGTT
CTGAGGGTCCTGCCTAGGCTGAATGAAGATGTAAACGAAGAGTGGATTTCTGATAAGACGCGGTTTGCATATGATGGTTT
GGCTTTGCAGCGGTTGGATAAGCCATGTGTTCGTAAGGATGATAGGCTTGTAGAAGTAAGTTGGGATGATGCTATTGAGA
TAGCTGCGGGCAGATTATCTGGTGTTCAGCGTGGTAAAATTGCAGCAATTGCAGGGGACTTAGTGGATTGCGAGTCTATG
TTTCTTCTTCGGAGGCTTATGTTTCATCTTGGAAGTAGCATCATGGATTGTAGGCAAGATGGGGCTAAACTGAGTGCCCT
TGCTAGGAATATGTATCTCTTTAATACATCAATCGCGGGGATAGAAGCGGCGGATTTCTGTTTGTTAATTAATGCAGATT
TGAGAGTAGATGCTCCTATTATAAATGCTAGAGTGCGTAAGCAATATCTTGAGAGGGGTATGCGCATAGCATCTATAGGA
TGTAATTTTAGCTATAACTATCAAGTTGATCATCTCGGTGATGATATGGCGTTGCTGGGGGAGATATACAATGGCGATCA
TGAGCTATGTAAGGCTTTGATGGCTGCTGAGCATCCTATAATAATTTTGGGGCAGGATGCTATTGTGGGTGATAAAGGGC
ATGCTGTGCTAATGAATGTGCTGCGTATTGCTCGGAAATTTAATATTGTGCGAGATGGTTGGAATGGGTTTAACGTCTTG
CATAAAGCTGCGGCAAGGGTAGGTGGTTTAGATGTTGGTTTTTTGCCGGAAGATCCGGTGAATTTCGGTGTTTCAGATAT
ACTTTCTGCTGCTGCGAGTAATGATGTACAGGTGTTATATTTACTTGGTGCTGATGAGGTAGATATTTTTTCCGTAAAAT
CTAAGAATCCTGATCTCTTTGTTATATATCAGGGGCATCATGCTGATCGAGGAGCGCAAGTGGCTGATCTCATATTGCCG
GGCGCTGCATATACGGAAAAGAGGGCTACTTATGTTAATACTGAAGGTAGAGTGCAGCGTACAGAGTTTGCAGTGCGATC
TCCAGGGGAAGCGAGAGAGGATTGGAGAGTAATTAGTGATCTTGCTGAGAGGTTAGGGTGTCCTTTTGGCTATGAATCGG
TCTTTGATGTCTGGAAAGGGTTAGCTGCTCTTGGTGCGCAATTTGAAGATGGTAATATAGGCAAGCTTGTGGCTTCTGAG
GGAGATTTTTCTAAGGCTTTTGATTTGGAGGGTGTCGATTCTTCGCTTGAAGGCAAGTTTACGGTCGTTGGGAAGAATTT
TTATATGACTGACCCTATAAGCAGGGCTTCGCCTACTATGGCTAAGTGTACTAAGTTTTTTATGAGGCAAGTCTGCTGA

Upstream 100 bases:

>100_bases
TAAGGGGCAAGTCTTCATGGCTGCTCAGTTTGATGATGAGAGCCTGGTGAAGGGAGCTAATGGTGTTCCTCTCGAATGGT
CTAGTATATAGAGGTCTGTT

Downstream 100 bases:

>100_bases
TATGGATACTTTGTATGCTTTATATGGGTGGTTAGTTGCTTCGGGAATGCAGCTAGTAGGTATGGTCGCCTTGATGGTGG
GTGTACTTGTGAGTGTTGCG

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 692; Mature: 692

Protein sequence:

>692_residues
MVEVTVNSVSINVEDGMTVLQACEIAGVEIPRFCYHERLAIAGNCRMCLVEIVGQPKLAASCAMPIANGMVINTDTEKVK
KARKGVLELLLVNHPLDCPICDQGGECDLQDQVVAYGCGIGRYHEEKRAVSKKAFGPLIENSMNRCIHCTRCVRFLSDVA
GTYEFGTFGRGEKMEIDTCVEQGVTSELSGNIIDLCPVGALTSKPYAFKARPWELYHCDTIDVMDAVGCSIRVDCRGLNV
LRVLPRLNEDVNEEWISDKTRFAYDGLALQRLDKPCVRKDDRLVEVSWDDAIEIAAGRLSGVQRGKIAAIAGDLVDCESM
FLLRRLMFHLGSSIMDCRQDGAKLSALARNMYLFNTSIAGIEAADFCLLINADLRVDAPIINARVRKQYLERGMRIASIG
CNFSYNYQVDHLGDDMALLGEIYNGDHELCKALMAAEHPIIILGQDAIVGDKGHAVLMNVLRIARKFNIVRDGWNGFNVL
HKAAARVGGLDVGFLPEDPVNFGVSDILSAAASNDVQVLYLLGADEVDIFSVKSKNPDLFVIYQGHHADRGAQVADLILP
GAAYTEKRATYVNTEGRVQRTEFAVRSPGEAREDWRVISDLAERLGCPFGYESVFDVWKGLAALGAQFEDGNIGKLVASE
GDFSKAFDLEGVDSSLEGKFTVVGKNFYMTDPISRASPTMAKCTKFFMRQVC

Sequences:

>Translated_692_residues
MVEVTVNSVSINVEDGMTVLQACEIAGVEIPRFCYHERLAIAGNCRMCLVEIVGQPKLAASCAMPIANGMVINTDTEKVK
KARKGVLELLLVNHPLDCPICDQGGECDLQDQVVAYGCGIGRYHEEKRAVSKKAFGPLIENSMNRCIHCTRCVRFLSDVA
GTYEFGTFGRGEKMEIDTCVEQGVTSELSGNIIDLCPVGALTSKPYAFKARPWELYHCDTIDVMDAVGCSIRVDCRGLNV
LRVLPRLNEDVNEEWISDKTRFAYDGLALQRLDKPCVRKDDRLVEVSWDDAIEIAAGRLSGVQRGKIAAIAGDLVDCESM
FLLRRLMFHLGSSIMDCRQDGAKLSALARNMYLFNTSIAGIEAADFCLLINADLRVDAPIINARVRKQYLERGMRIASIG
CNFSYNYQVDHLGDDMALLGEIYNGDHELCKALMAAEHPIIILGQDAIVGDKGHAVLMNVLRIARKFNIVRDGWNGFNVL
HKAAARVGGLDVGFLPEDPVNFGVSDILSAAASNDVQVLYLLGADEVDIFSVKSKNPDLFVIYQGHHADRGAQVADLILP
GAAYTEKRATYVNTEGRVQRTEFAVRSPGEAREDWRVISDLAERLGCPFGYESVFDVWKGLAALGAQFEDGNIGKLVASE
GDFSKAFDLEGVDSSLEGKFTVVGKNFYMTDPISRASPTMAKCTKFFMRQVC
>Mature_692_residues
MVEVTVNSVSINVEDGMTVLQACEIAGVEIPRFCYHERLAIAGNCRMCLVEIVGQPKLAASCAMPIANGMVINTDTEKVK
KARKGVLELLLVNHPLDCPICDQGGECDLQDQVVAYGCGIGRYHEEKRAVSKKAFGPLIENSMNRCIHCTRCVRFLSDVA
GTYEFGTFGRGEKMEIDTCVEQGVTSELSGNIIDLCPVGALTSKPYAFKARPWELYHCDTIDVMDAVGCSIRVDCRGLNV
LRVLPRLNEDVNEEWISDKTRFAYDGLALQRLDKPCVRKDDRLVEVSWDDAIEIAAGRLSGVQRGKIAAIAGDLVDCESM
FLLRRLMFHLGSSIMDCRQDGAKLSALARNMYLFNTSIAGIEAADFCLLINADLRVDAPIINARVRKQYLERGMRIASIG
CNFSYNYQVDHLGDDMALLGEIYNGDHELCKALMAAEHPIIILGQDAIVGDKGHAVLMNVLRIARKFNIVRDGWNGFNVL
HKAAARVGGLDVGFLPEDPVNFGVSDILSAAASNDVQVLYLLGADEVDIFSVKSKNPDLFVIYQGHHADRGAQVADLILP
GAAYTEKRATYVNTEGRVQRTEFAVRSPGEAREDWRVISDLAERLGCPFGYESVFDVWKGLAALGAQFEDGNIGKLVASE
GDFSKAFDLEGVDSSLEGKFTVVGKNFYMTDPISRASPTMAKCTKFFMRQVC

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=696, Percent_Identity=48.9942528735632, Blast_Score=653, Evalue=0.0,
Organism=Escherichia coli, GI145693161, Length=684, Percent_Identity=26.4619883040936, Blast_Score=209, Evalue=5e-55,
Organism=Escherichia coli, GI3868721, Length=173, Percent_Identity=26.0115606936416, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17565758, Length=698, Percent_Identity=43.6962750716332, Blast_Score=565, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI32566231, Length=587, Percent_Identity=47.1890971039182, Blast_Score=535, Evalue=1e-152,
Organism=Caenorhabditis elegans, GI193209088, Length=251, Percent_Identity=57.7689243027888, Blast_Score=310, Evalue=1e-84,
Organism=Drosophila melanogaster, GI24640559, Length=702, Percent_Identity=46.4387464387464, Blast_Score=597, Evalue=1e-170,
Organism=Drosophila melanogaster, GI24640557, Length=702, Percent_Identity=46.4387464387464, Blast_Score=597, Evalue=1e-170,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 76058; Mature: 76058

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEVTVNSVSINVEDGMTVLQACEIAGVEIPRFCYHERLAIAGNCRMCLVEIVGQPKLAA
CEEEEEEEEEEECCCCHHHHHHHHHCCCCCCHHHHHCCEEECCCCCEEEEHHHCCCCHHH
SCAMPIANGMVINTDTEKVKKARKGVLELLLVNHPLDCPICDQGGECDLQDQVVAYGCGI
HHCCHHHCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCC
GRYHEEKRAVSKKAFGPLIENSMNRCIHCTRCVRFLSDVAGTYEFGTFGRGEKMEIDTCV
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHH
EQGVTSELSGNIIDLCPVGALTSKPYAFKARPWELYHCDTIDVMDAVGCSIRVDCRGLNV
HCCCCHHHCCCEEEECCCCCCCCCCCEEECCCEEEEECCCHHHHHHCCCEEEEECCCCHH
LRVLPRLNEDVNEEWISDKTRFAYDGLALQRLDKPCVRKDDRLVEVSWDDAIEIAAGRLS
HHHHHHHCCCCCHHHHCCCCHHEECCHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHC
GVQRGKIAAIAGDLVDCESMFLLRRLMFHLGSSIMDCRQDGAKLSALARNMYLFNTSIAG
CCCCCCEEEECCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHEEEEECCCCC
IEAADFCLLINADLRVDAPIINARVRKQYLERGMRIASIGCNFSYNYQVDHLGDDMALLG
CCCCCEEEEEECCCEECCHHHHHHHHHHHHHCCCEEEEECCCEEEEEEHHCCCCCHHHHH
EIYNGDHELCKALMAAEHPIIILGQDAIVGDKGHAVLMNVLRIARKFNIVRDGWNGFNVL
HHHCCCHHHHHHHHHCCCCEEEEECCEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
HKAAARVGGLDVGFLPEDPVNFGVSDILSAAASNDVQVLYLLGADEVDIFSVKSKNPDLF
HHHHHHHCCCEECCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCEEEEEEECCCCCEE
VIYQGHHADRGAQVADLILPGAAYTEKRATYVNTEGRVQRTEFAVRSPGEAREDWRVISD
EEECCCCCCCCCCEEHHEECCCCCCCCCCEEECCCCCEEEEEEEECCCCCHHHHHHHHHH
LAERLGCPFGYESVFDVWKGLAALGAQFEDGNIGKLVASEGDFSKAFDLEGVDSSLEGKF
HHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEECCCCCCCCCCCEE
TVVGKNFYMTDPISRASPTMAKCTKFFMRQVC
EEEECCEEECCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MVEVTVNSVSINVEDGMTVLQACEIAGVEIPRFCYHERLAIAGNCRMCLVEIVGQPKLAA
CEEEEEEEEEEECCCCHHHHHHHHHCCCCCCHHHHHCCEEECCCCCEEEEHHHCCCCHHH
SCAMPIANGMVINTDTEKVKKARKGVLELLLVNHPLDCPICDQGGECDLQDQVVAYGCGI
HHCCHHHCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCC
GRYHEEKRAVSKKAFGPLIENSMNRCIHCTRCVRFLSDVAGTYEFGTFGRGEKMEIDTCV
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHH
EQGVTSELSGNIIDLCPVGALTSKPYAFKARPWELYHCDTIDVMDAVGCSIRVDCRGLNV
HCCCCHHHCCCEEEECCCCCCCCCCCEEECCCEEEEECCCHHHHHHCCCEEEEECCCCHH
LRVLPRLNEDVNEEWISDKTRFAYDGLALQRLDKPCVRKDDRLVEVSWDDAIEIAAGRLS
HHHHHHHCCCCCHHHHCCCCHHEECCHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHC
GVQRGKIAAIAGDLVDCESMFLLRRLMFHLGSSIMDCRQDGAKLSALARNMYLFNTSIAG
CCCCCCEEEECCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHEEEEECCCCC
IEAADFCLLINADLRVDAPIINARVRKQYLERGMRIASIGCNFSYNYQVDHLGDDMALLG
CCCCCEEEEEECCCEECCHHHHHHHHHHHHHCCCEEEEECCCEEEEEEHHCCCCCHHHHH
EIYNGDHELCKALMAAEHPIIILGQDAIVGDKGHAVLMNVLRIARKFNIVRDGWNGFNVL
HHHCCCHHHHHHHHHCCCCEEEEECCEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
HKAAARVGGLDVGFLPEDPVNFGVSDILSAAASNDVQVLYLLGADEVDIFSVKSKNPDLF
HHHHHHHCCCEECCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCEEEEEEECCCCCEE
VIYQGHHADRGAQVADLILPGAAYTEKRATYVNTEGRVQRTEFAVRSPGEAREDWRVISD
EEECCCCCCCCCCEEHHEECCCCCCCCCCEEECCCCCEEEEEEEECCCCCHHHHHHHHHH
LAERLGCPFGYESVFDVWKGLAALGAQFEDGNIGKLVASEGDFSKAFDLEGVDSSLEGKF
HHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEECCCCCCCCCCCEE
TVVGKNFYMTDPISRASPTMAKCTKFFMRQVC
EEEECCEEECCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA