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The map label for this gene is rpoC [H]

Identifier: 88607105

GI number: 88607105

Start: 1082696

End: 1086925

Strand: Reverse

Name: rpoC [H]

Synonym: APH_1023

Alternate gene names: 88607105

Gene position: 1086925-1082696 (Counterclockwise)

Preceding gene: 88606872

Following gene: 88607222

Centisome position: 73.88

GC content: 44.23

Gene sequence:

>4230_bases
ATGAAGACGTTGGATTTGTATGGCTATACCAGTATAGCACAGTCGTTCGATAAGATTTGCATATCCATAGCTAGTCCAGA
AAGTATAAGGGCTATGTCCTATGGAGAAATCAAGGATATCTCTACTACTAACTATCGTACCTTTAAGGTGGAGAAGGGGG
GGCTATTCTGTCCTAAGATCTTTGGTCCGGTTAATGATGACGAGTGTCTTTGTGGTAAGTATAGGAAAAAGCGCTACAGG
GGCATTGTCTGTGAGAAATGCGGAGTGGAGGTAACTTCTTCTAAAGTTAGAAGAGAGAGAATGGGGCACATAGAGTTGGT
CTCACCTGTTGCTCATATTTGGTTTCTTAAATCCCTGCCGTCACGTATAGGTGCTCTGCTAGACATGCCTTTAAAGGCTA
TAGAGAATATACTATATAGTGGAGATTTTGTAGTAATTGATCCGGTAGCTACTCCTTTTGCTAAGGGGGAAGTAATCAGT
GAGGTAGTTTATAATCAGGCGCGGGATGCCTATGGTGAGGATGGATTTTTTGCGCTCACTGGTGTTGAAGCTATAAAGGA
GTTGCTAACTCGCCTTGATTTGGAGGCTATCAGGGCTACTTTGAGGAATGAGCTTGAGTCAACTTCTTCGGAAATGAAGC
GTAAGAAGGTTGTTAAGAGGCTCAGGCTTGTTGAGAATTTTATTAAGTCTGGTAATAGGCCGGAGTGGATGATCTTGACT
GTAATTCCTGTTCTTCCACCGGATTTGAGGCCGTTGGTATCACTGGAAAATGGTAGACCTGCGGTATCAGATTTAAATCA
CCATTACAGGACTATAATAAACCGTAATAACAGATTGGAAAAGCTACTCAAGCTGAATCCTCCTGCGATCATGATACGCA
ATGAAAAGAGGATGTTGCAAGAAGCGGTAGATGCTCTGTTTGACAGCAGTCGGCGTAGTTACGTTTCCAGTAGAGTTGGA
AGCATGGGCTATAAGAAGTCTCTTAGCGACATGCTAAAGGGTAAGCAGGGTAGGTTTAGGCAGAACTTGCTTGGTAAAAG
GGTTGACTATTCTGGTAGGTCAGTAATAGTTGTGGGCCCTAGTTTGAAGCTGCATCAGTGTGGTTTGCCCAAGAAGATGG
CTCTTGAGCTGTTCAAGCCGTTCATTTGTTCTAAGCTGAAGATGTACGGTATTGCTCCGACTGTGAAGTTGGCTAACAAG
ATGATTCAGAGTGAGAAGCCTGATGTTTGGGATGTTTTGGATGAAGTGATTAAAGAGCATCCTATTCTCCTTAATAGGGC
TCCTACACTGCATAGATTGGGTCTTCAGGCGTTTGATCCTGTATTGATAGAAGGTAAGGCAATACAGTTGCATCCGTTGG
TATGTAGTGCGTTTAATGCCGATTTCGATGGTGATCAGATGGCGGTACACGTGCCATTGTCTCAAGAGGCGCAGCTTGAG
GCGCGCGTGTTGATGATGTCTACAAATAACATCTTGAGTCCTTCTAACGGTAGGCCAATTATAGTTCCGTCTAAGGATAT
CGTTCTTGGGATATACTATTTAACGTTGTTGGAAGAAGATCCTGAAGTGCGTGAAGTGCAGACTTTTGCGGAGTTCAGCC
ACGTGGAGTACGCATTGCATGAGGGGATTGTGCATACGTGCTCAAGGATAAAGTACAGAATGCAGAAGAGTGCAGCTGAT
GGTACTGTATCTAGCGAAATAGTTGAGACTACGCCTGGTAGGTTGATATTGTGGCAGATATTCCCGCAGCATAAGGATTT
GACTTTTGACTTGATCAACCAAGTGCTTACGGTTAAGGAAATCACCTCCATTGTGGATCTTGTCTATAGAAGTTGTGGTC
AGAGGGAGACGGTAGAGTTCTCTGACAAACTGATGTATTTGGGATTCAAGTATGCTTCGCAATCAGGTATTTCTTTTGGT
TGTAAGGATATGATTATTCCTGATACTAAGGCTGCGCACGTTGAAGATGCTAGCGAAAAGATCAGGGAATTCTCTATACA
GTATCAGGATGGTTTGATAACCAAGAGCGAGCGCTATAACAAAGTGGTTGATGAGTGGTCTAAGTGTACCGATTTGATTG
CTAGGGATATGATGAAGGCTATATCTTTATGTGATGAGAAAGGGAAATATAACTCGATTTACATGATGGCGAATTCTGGG
GCTAGAGGTTCTGCGTCTCAGATGAAGCAGCTTGCTGGTATGAGAGGTCTGATGGCGAAACCGTCAGGTGAGATTATTGA
GACTCCGATTATTTCGAATTTTAGGGAAGGGTTGAGTGTATTTGAATATTTCAATTCTACTCACGGGGCTCGTAAAGGTC
TTGCTGATACAGCATTGAAGACTGCTAACTCCGGATATCTAACTCGTAGGCTTGTAGATGTAGCGCAGGATTGTACAGTT
GTTGAACATGATTGCGGCACTAGCGGGGGCGTTGTTGCGAGAGCGGTCATAGAGGGTGGTGTTGTAGTAGCAACGCTGGA
TAGTGTGGTATTAGGAAGGGTTGCTGCTGTAGATACCTATAATCCTGTTACAGGAGAGAAGTTATTTACTTCAGGTGAGC
TTATTGATGAAAGCAAGCTTGATAAGATAAGAGTTGCGGGATTAGATGCGGTGAAGGTGCGGTCACCGCTTACTTGTGAG
TCCAAACAAGGTATTTGTGCTCTATGTTATGGTAGAGATCTAGCTATTGGGGATTTGGTGTCCATAGGGGAAGCTGTAGG
TGTGATCGCTGCTCAGTCTGTTGGGGAACCGGGTACACAGCTGACGATGAGAACGTTCCACGTTGGTGGTACTGCTATGC
GTGGTGTTGAGGTATCTAATCTGATAGCCTTGATGGATGCGACTGTTAAGCTGGTTAACAGTAATGTGGTTACTGACAAG
TACGGTAATCAGATAGTTATGAGTAGGTCGTGTGAAGTTGTGCTGCTGGATGCTGCGGGCAATGAGAAGATGCGGCATAG
TGTGCCATATGGCGCTAAGTTGTATGCTACCGAAGGGCAATCGGTGAGTATGATGGAGAAGATTGCTGAGTGGGATCCTT
ATACTATACCTATTATCACTGAGAAGACAGGTACTATAAAGTATGTGGACCTTATATATGGGGTCTCTATCAACGAGGTA
CTTGATGAGTCGACTGGTATTTCTAACAGGGTGGTTGTAGATTGGAAGATGCATTTACAAGGTGCAAATCTGCGGCCTAG
GCTTGTGTTGCTAGACGATAATGGTGCTGTGGTTACATTATCGAGTGACTTGGAAGCTAGTTATTTTGTCCCGATAGGTG
CGGTATTGAATGTACAGGATGGGCAAAGGGTACATGCTGGTGATGTTATCACGAGGATACCTAGGGGTTCTATCAAGACG
CGTGATATTACGGGTGGTCTACCTAGGGTTATAGAGCTGTTTGAAGCTCGTAAGCCGAAGGAGCATGCTATTGTTAGTGA
CGTTGATGGATACGTTGAGTTCGGTAAGGATTATTACCGTTCGAAGAGGCGTATATTTATACGTCCTGTAGACAAGAGCT
TGCCTGTAGTTGAATATCTAGTTCCTAAGGGTAAGCACACAATAGTCAATGAGGGTGATTTTGTGCATAAGGGTGATCTG
TTAATGGACGGTGATCCTGATCAGCACGATATCCTTAGGGTGTTAGGAACTGAAGCGCTGGCAAATTACATGATATCCGA
GATCCAGCAGGTATATAGGTTGCAGGGTGTTAAGATAGACAACAAGCACATAGAGGTGATACTCAGGCAGATGTTGCAGA
AGGTAGAGATTACTGAGCCGGGTGATACAATGTACCTGATAGGCGAGCATGTGTCTCGTGAAGAGGTTATGAAGCTGAAT
AGGAAGCTTGCTGAGGCTGGAAAGAAAGAAGTTTCTTATGTGCCGATACTGCAGGGGATCACTAAGGCTAGTCTGGATAC
TAACTCTTTCATATCTGCTGCGTCATTCCAGGAGACAACTAAGGTATTGACTGAGGCGGCTTTTGCAGGAAAAGAAGATC
CTCTATATGGGTTGAAGGAAAATGTGATTGTCGGTCGTCTGATACCAGCAGGTACAGGGTTCATAATGAACAAGATCAAG
AAGCTTGCTATGCTTGATCAGAGCGACTATGCAACATATTACAATAGCGAATTGCGAGGAATCATGGGTGATTTGGGAAG
CTCTATAATCGAAGAGTTTCAAACTCCAGCTCCTGATGGTAGCATAAGCGGCTCCGTTGTGGATTACTAG

Upstream 100 bases:

>100_bases
TAATGTCATGGTCAAGGAGTTACGCTCGCTGTGCCTTGATGTTGTTCTAAAGCAGGATAAAGAGTTTACTAGTAGCAAGG
TGGAGTAGGGATTTACAATT

Downstream 100 bases:

>100_bases
GGTAATTACGTAGGATATTGTGGTAGGGTTCTCAGAGATGAGGTACTCTACTGCAATCTTATAAGTGCTGTATAGGGCAG
CCTTGATGGGTTCGGTGTTT

Product: DNA-directed RNA polymerase, beta' subunit

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1409; Mature: 1409

Protein sequence:

>1409_residues
MKTLDLYGYTSIAQSFDKICISIASPESIRAMSYGEIKDISTTNYRTFKVEKGGLFCPKIFGPVNDDECLCGKYRKKRYR
GIVCEKCGVEVTSSKVRRERMGHIELVSPVAHIWFLKSLPSRIGALLDMPLKAIENILYSGDFVVIDPVATPFAKGEVIS
EVVYNQARDAYGEDGFFALTGVEAIKELLTRLDLEAIRATLRNELESTSSEMKRKKVVKRLRLVENFIKSGNRPEWMILT
VIPVLPPDLRPLVSLENGRPAVSDLNHHYRTIINRNNRLEKLLKLNPPAIMIRNEKRMLQEAVDALFDSSRRSYVSSRVG
SMGYKKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPSLKLHQCGLPKKMALELFKPFICSKLKMYGIAPTVKLANK
MIQSEKPDVWDVLDEVIKEHPILLNRAPTLHRLGLQAFDPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSQEAQLE
ARVLMMSTNNILSPSNGRPIIVPSKDIVLGIYYLTLLEEDPEVREVQTFAEFSHVEYALHEGIVHTCSRIKYRMQKSAAD
GTVSSEIVETTPGRLILWQIFPQHKDLTFDLINQVLTVKEITSIVDLVYRSCGQRETVEFSDKLMYLGFKYASQSGISFG
CKDMIIPDTKAAHVEDASEKIREFSIQYQDGLITKSERYNKVVDEWSKCTDLIARDMMKAISLCDEKGKYNSIYMMANSG
ARGSASQMKQLAGMRGLMAKPSGEIIETPIISNFREGLSVFEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDCTV
VEHDCGTSGGVVARAVIEGGVVVATLDSVVLGRVAAVDTYNPVTGEKLFTSGELIDESKLDKIRVAGLDAVKVRSPLTCE
SKQGICALCYGRDLAIGDLVSIGEAVGVIAAQSVGEPGTQLTMRTFHVGGTAMRGVEVSNLIALMDATVKLVNSNVVTDK
YGNQIVMSRSCEVVLLDAAGNEKMRHSVPYGAKLYATEGQSVSMMEKIAEWDPYTIPIITEKTGTIKYVDLIYGVSINEV
LDESTGISNRVVVDWKMHLQGANLRPRLVLLDDNGAVVTLSSDLEASYFVPIGAVLNVQDGQRVHAGDVITRIPRGSIKT
RDITGGLPRVIELFEARKPKEHAIVSDVDGYVEFGKDYYRSKRRIFIRPVDKSLPVVEYLVPKGKHTIVNEGDFVHKGDL
LMDGDPDQHDILRVLGTEALANYMISEIQQVYRLQGVKIDNKHIEVILRQMLQKVEITEPGDTMYLIGEHVSREEVMKLN
RKLAEAGKKEVSYVPILQGITKASLDTNSFISAASFQETTKVLTEAAFAGKEDPLYGLKENVIVGRLIPAGTGFIMNKIK
KLAMLDQSDYATYYNSELRGIMGDLGSSIIEEFQTPAPDGSISGSVVDY

Sequences:

>Translated_1409_residues
MKTLDLYGYTSIAQSFDKICISIASPESIRAMSYGEIKDISTTNYRTFKVEKGGLFCPKIFGPVNDDECLCGKYRKKRYR
GIVCEKCGVEVTSSKVRRERMGHIELVSPVAHIWFLKSLPSRIGALLDMPLKAIENILYSGDFVVIDPVATPFAKGEVIS
EVVYNQARDAYGEDGFFALTGVEAIKELLTRLDLEAIRATLRNELESTSSEMKRKKVVKRLRLVENFIKSGNRPEWMILT
VIPVLPPDLRPLVSLENGRPAVSDLNHHYRTIINRNNRLEKLLKLNPPAIMIRNEKRMLQEAVDALFDSSRRSYVSSRVG
SMGYKKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPSLKLHQCGLPKKMALELFKPFICSKLKMYGIAPTVKLANK
MIQSEKPDVWDVLDEVIKEHPILLNRAPTLHRLGLQAFDPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSQEAQLE
ARVLMMSTNNILSPSNGRPIIVPSKDIVLGIYYLTLLEEDPEVREVQTFAEFSHVEYALHEGIVHTCSRIKYRMQKSAAD
GTVSSEIVETTPGRLILWQIFPQHKDLTFDLINQVLTVKEITSIVDLVYRSCGQRETVEFSDKLMYLGFKYASQSGISFG
CKDMIIPDTKAAHVEDASEKIREFSIQYQDGLITKSERYNKVVDEWSKCTDLIARDMMKAISLCDEKGKYNSIYMMANSG
ARGSASQMKQLAGMRGLMAKPSGEIIETPIISNFREGLSVFEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDCTV
VEHDCGTSGGVVARAVIEGGVVVATLDSVVLGRVAAVDTYNPVTGEKLFTSGELIDESKLDKIRVAGLDAVKVRSPLTCE
SKQGICALCYGRDLAIGDLVSIGEAVGVIAAQSVGEPGTQLTMRTFHVGGTAMRGVEVSNLIALMDATVKLVNSNVVTDK
YGNQIVMSRSCEVVLLDAAGNEKMRHSVPYGAKLYATEGQSVSMMEKIAEWDPYTIPIITEKTGTIKYVDLIYGVSINEV
LDESTGISNRVVVDWKMHLQGANLRPRLVLLDDNGAVVTLSSDLEASYFVPIGAVLNVQDGQRVHAGDVITRIPRGSIKT
RDITGGLPRVIELFEARKPKEHAIVSDVDGYVEFGKDYYRSKRRIFIRPVDKSLPVVEYLVPKGKHTIVNEGDFVHKGDL
LMDGDPDQHDILRVLGTEALANYMISEIQQVYRLQGVKIDNKHIEVILRQMLQKVEITEPGDTMYLIGEHVSREEVMKLN
RKLAEAGKKEVSYVPILQGITKASLDTNSFISAASFQETTKVLTEAAFAGKEDPLYGLKENVIVGRLIPAGTGFIMNKIK
KLAMLDQSDYATYYNSELRGIMGDLGSSIIEEFQTPAPDGSISGSVVDY
>Mature_1409_residues
MKTLDLYGYTSIAQSFDKICISIASPESIRAMSYGEIKDISTTNYRTFKVEKGGLFCPKIFGPVNDDECLCGKYRKKRYR
GIVCEKCGVEVTSSKVRRERMGHIELVSPVAHIWFLKSLPSRIGALLDMPLKAIENILYSGDFVVIDPVATPFAKGEVIS
EVVYNQARDAYGEDGFFALTGVEAIKELLTRLDLEAIRATLRNELESTSSEMKRKKVVKRLRLVENFIKSGNRPEWMILT
VIPVLPPDLRPLVSLENGRPAVSDLNHHYRTIINRNNRLEKLLKLNPPAIMIRNEKRMLQEAVDALFDSSRRSYVSSRVG
SMGYKKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPSLKLHQCGLPKKMALELFKPFICSKLKMYGIAPTVKLANK
MIQSEKPDVWDVLDEVIKEHPILLNRAPTLHRLGLQAFDPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSQEAQLE
ARVLMMSTNNILSPSNGRPIIVPSKDIVLGIYYLTLLEEDPEVREVQTFAEFSHVEYALHEGIVHTCSRIKYRMQKSAAD
GTVSSEIVETTPGRLILWQIFPQHKDLTFDLINQVLTVKEITSIVDLVYRSCGQRETVEFSDKLMYLGFKYASQSGISFG
CKDMIIPDTKAAHVEDASEKIREFSIQYQDGLITKSERYNKVVDEWSKCTDLIARDMMKAISLCDEKGKYNSIYMMANSG
ARGSASQMKQLAGMRGLMAKPSGEIIETPIISNFREGLSVFEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDCTV
VEHDCGTSGGVVARAVIEGGVVVATLDSVVLGRVAAVDTYNPVTGEKLFTSGELIDESKLDKIRVAGLDAVKVRSPLTCE
SKQGICALCYGRDLAIGDLVSIGEAVGVIAAQSVGEPGTQLTMRTFHVGGTAMRGVEVSNLIALMDATVKLVNSNVVTDK
YGNQIVMSRSCEVVLLDAAGNEKMRHSVPYGAKLYATEGQSVSMMEKIAEWDPYTIPIITEKTGTIKYVDLIYGVSINEV
LDESTGISNRVVVDWKMHLQGANLRPRLVLLDDNGAVVTLSSDLEASYFVPIGAVLNVQDGQRVHAGDVITRIPRGSIKT
RDITGGLPRVIELFEARKPKEHAIVSDVDGYVEFGKDYYRSKRRIFIRPVDKSLPVVEYLVPKGKHTIVNEGDFVHKGDL
LMDGDPDQHDILRVLGTEALANYMISEIQQVYRLQGVKIDNKHIEVILRQMLQKVEITEPGDTMYLIGEHVSREEVMKLN
RKLAEAGKKEVSYVPILQGITKASLDTNSFISAASFQETTKVLTEAAFAGKEDPLYGLKENVIVGRLIPAGTGFIMNKIK
KLAMLDQSDYATYYNSELRGIMGDLGSSIIEEFQTPAPDGSISGSVVDY

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=651, Percent_Identity=26.1136712749616, Blast_Score=165, Evalue=4e-40,
Organism=Homo sapiens, GI39725938, Length=569, Percent_Identity=25.8347978910369, Blast_Score=141, Evalue=4e-33,
Organism=Homo sapiens, GI103471997, Length=240, Percent_Identity=30.8333333333333, Blast_Score=97, Evalue=8e-20,
Organism=Escherichia coli, GI2367335, Length=1357, Percent_Identity=55.5637435519528, Blast_Score=1474, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=676, Percent_Identity=25.5917159763314, Blast_Score=171, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI71987878, Length=659, Percent_Identity=24.886191198786, Blast_Score=154, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6320061, Length=684, Percent_Identity=26.7543859649123, Blast_Score=165, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6324690, Length=317, Percent_Identity=29.9684542586751, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI281360912, Length=861, Percent_Identity=24.9709639953542, Blast_Score=161, Evalue=3e-39,
Organism=Drosophila melanogaster, GI17530899, Length=556, Percent_Identity=25.1798561151079, Blast_Score=147, Evalue=6e-35,
Organism=Drosophila melanogaster, GI17647875, Length=350, Percent_Identity=26.2857142857143, Blast_Score=95, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 156246; Mature: 156246

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLDLYGYTSIAQSFDKICISIASPESIRAMSYGEIKDISTTNYRTFKVEKGGLFCPKI
CCCEEECCHHHHHHHHHHHEEEECCCCHHEECCCCCCCCCCCCCEEEEEEECCCEECHHH
FGPVNDDECLCGKYRKKRYRGIVCEKCGVEVTSSKVRRERMGHIELVSPVAHIWFLKSLP
CCCCCCCCHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SRIGALLDMPLKAIENILYSGDFVVIDPVATPFAKGEVISEVVYNQARDAYGEDGFFALT
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEH
GVEAIKELLTRLDLEAIRATLRNELESTSSEMKRKKVVKRLRLVENFIKSGNRPEWMILT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VIPVLPPDLRPLVSLENGRPAVSDLNHHYRTIINRNNRLEKLLKLNPPAIMIRNEKRMLQ
EECCCCCCCCHHEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEECHHHHHH
EAVDALFDSSRRSYVSSRVGSMGYKKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGP
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECC
SLKLHQCGLPKKMALELFKPFICSKLKMYGIAPTVKLANKMIQSEKPDVWDVLDEVIKEH
CCEEHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHC
PILLNRAPTLHRLGLQAFDPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSQEAQLE
CEEEECCCHHHHHCHHHCCCEEEECCEEEEEHHHHHHCCCCCCCCCEEEEECCCCCCCCE
ARVLMMSTNNILSPSNGRPIIVPSKDIVLGIYYLTLLEEDPEVREVQTFAEFSHVEYALH
EEEEEEECCCCCCCCCCCEEEECCCHHHHHHHHEEHCCCCCCHHHHHHHHHHHHHHHHHH
EGIVHTCSRIKYRMQKSAADGTVSSEIVETTPGRLILWQIFPQHKDLTFDLINQVLTVKE
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
ITSIVDLVYRSCGQRETVEFSDKLMYLGFKYASQSGISFGCKDMIIPDTKAAHVEDASEK
HHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHH
IREFSIQYQDGLITKSERYNKVVDEWSKCTDLIARDMMKAISLCDEKGKYNSIYMMANSG
HHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
ARGSASQMKQLAGMRGLMAKPSGEIIETPIISNFREGLSVFEYFNSTHGARKGLADTALK
CCCCHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHH
TANSGYLTRRLVDVAQDCTVVEHDCGTSGGVVARAVIEGGVVVATLDSVVLGRVAAVDTY
HCCCCHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHEECCC
NPVTGEKLFTSGELIDESKLDKIRVAGLDAVKVRSPLTCESKQGICALCYGRDLAIGDLV
CCCCCCHHCCCCCCCCCCCCCEEEECCCCEEECCCCCCCCCCCCEEEEEECCCCCHHHHH
SIGEAVGVIAAQSVGEPGTQLTMRTFHVGGTAMRGVEVSNLIALMDATVKLVNSNVVTDK
HHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHCCCCHHHHHHHHHHHHHHHHCCCEEECC
YGNQIVMSRSCEVVLLDAAGNEKMRHSVPYGAKLYATEGQSVSMMEKIAEWDPYTIPIIT
CCCEEEEECCCCEEEEECCCCCCHHHCCCCCCEEEEECCCCHHHHHHHHCCCCEEEEEEE
EKTGTIKYVDLIYGVSINEVLDESTGISNRVVVDWKMHLQGANLRPRLVLLDDNGAVVTL
CCCCCEEEEHHEECCCHHHHHHHCCCCCCEEEEEEEEEECCCCCCCEEEEEECCCEEEEE
SSDLEASYFVPIGAVLNVQDGQRVHAGDVITRIPRGSIKTRDITGGLPRVIELFEARKPK
ECCCCCEEEEEECEEEECCCCCEEECCHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCC
EHAIVSDVDGYVEFGKDYYRSKRRIFIRPVDKSLPVVEYLVPKGKHTIVNEGDFVHKGDL
CCCHHHCCHHHHHHCHHHHCCCCEEEEEECCCCCCHHHHHCCCCCEEEECCCCEEECCCE
LMDGDPDQHDILRVLGTEALANYMISEIQQVYRLQGVKIDNKHIEVILRQMLQKVEITEP
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHCCCCCC
GDTMYLIGEHVSREEVMKLNRKLAEAGKKEVSYVPILQGITKASLDTNSFISAASFQETT
CCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
KVLTEAAFAGKEDPLYGLKENVIVGRLIPAGTGFIMNKIKKLAMLDQSDYATYYNSELRG
HHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IMGDLGSSIIEEFQTPAPDGSISGSVVDY
HHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKTLDLYGYTSIAQSFDKICISIASPESIRAMSYGEIKDISTTNYRTFKVEKGGLFCPKI
CCCEEECCHHHHHHHHHHHEEEECCCCHHEECCCCCCCCCCCCCEEEEEEECCCEECHHH
FGPVNDDECLCGKYRKKRYRGIVCEKCGVEVTSSKVRRERMGHIELVSPVAHIWFLKSLP
CCCCCCCCHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SRIGALLDMPLKAIENILYSGDFVVIDPVATPFAKGEVISEVVYNQARDAYGEDGFFALT
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEH
GVEAIKELLTRLDLEAIRATLRNELESTSSEMKRKKVVKRLRLVENFIKSGNRPEWMILT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VIPVLPPDLRPLVSLENGRPAVSDLNHHYRTIINRNNRLEKLLKLNPPAIMIRNEKRMLQ
EECCCCCCCCHHEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEECHHHHHH
EAVDALFDSSRRSYVSSRVGSMGYKKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGP
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECC
SLKLHQCGLPKKMALELFKPFICSKLKMYGIAPTVKLANKMIQSEKPDVWDVLDEVIKEH
CCEEHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHC
PILLNRAPTLHRLGLQAFDPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSQEAQLE
CEEEECCCHHHHHCHHHCCCEEEECCEEEEEHHHHHHCCCCCCCCCEEEEECCCCCCCCE
ARVLMMSTNNILSPSNGRPIIVPSKDIVLGIYYLTLLEEDPEVREVQTFAEFSHVEYALH
EEEEEEECCCCCCCCCCCEEEECCCHHHHHHHHEEHCCCCCCHHHHHHHHHHHHHHHHHH
EGIVHTCSRIKYRMQKSAADGTVSSEIVETTPGRLILWQIFPQHKDLTFDLINQVLTVKE
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
ITSIVDLVYRSCGQRETVEFSDKLMYLGFKYASQSGISFGCKDMIIPDTKAAHVEDASEK
HHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHH
IREFSIQYQDGLITKSERYNKVVDEWSKCTDLIARDMMKAISLCDEKGKYNSIYMMANSG
HHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
ARGSASQMKQLAGMRGLMAKPSGEIIETPIISNFREGLSVFEYFNSTHGARKGLADTALK
CCCCHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHH
TANSGYLTRRLVDVAQDCTVVEHDCGTSGGVVARAVIEGGVVVATLDSVVLGRVAAVDTY
HCCCCHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHEECCC
NPVTGEKLFTSGELIDESKLDKIRVAGLDAVKVRSPLTCESKQGICALCYGRDLAIGDLV
CCCCCCHHCCCCCCCCCCCCCEEEECCCCEEECCCCCCCCCCCCEEEEEECCCCCHHHHH
SIGEAVGVIAAQSVGEPGTQLTMRTFHVGGTAMRGVEVSNLIALMDATVKLVNSNVVTDK
HHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHCCCCHHHHHHHHHHHHHHHHCCCEEECC
YGNQIVMSRSCEVVLLDAAGNEKMRHSVPYGAKLYATEGQSVSMMEKIAEWDPYTIPIIT
CCCEEEEECCCCEEEEECCCCCCHHHCCCCCCEEEEECCCCHHHHHHHHCCCCEEEEEEE
EKTGTIKYVDLIYGVSINEVLDESTGISNRVVVDWKMHLQGANLRPRLVLLDDNGAVVTL
CCCCCEEEEHHEECCCHHHHHHHCCCCCCEEEEEEEEEECCCCCCCEEEEEECCCEEEEE
SSDLEASYFVPIGAVLNVQDGQRVHAGDVITRIPRGSIKTRDITGGLPRVIELFEARKPK
ECCCCCEEEEEECEEEECCCCCEEECCHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCC
EHAIVSDVDGYVEFGKDYYRSKRRIFIRPVDKSLPVVEYLVPKGKHTIVNEGDFVHKGDL
CCCHHHCCHHHHHHCHHHHCCCCEEEEEECCCCCCHHHHHCCCCCEEEECCCCEEECCCE
LMDGDPDQHDILRVLGTEALANYMISEIQQVYRLQGVKIDNKHIEVILRQMLQKVEITEP
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHCCCCCC
GDTMYLIGEHVSREEVMKLNRKLAEAGKKEVSYVPILQGITKASLDTNSFISAASFQETT
CCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
KVLTEAAFAGKEDPLYGLKENVIVGRLIPAGTGFIMNKIKKLAMLDQSDYATYYNSELRG
HHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IMGDLGSSIIEEFQTPAPDGSISGSVVDY
HHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA