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The map label for this gene is yciK [H]

Identifier: 88607033

GI number: 88607033

Start: 236489

End: 237235

Strand: Direct

Name: yciK [H]

Synonym: APH_0236

Alternate gene names: 88607033

Gene position: 236489-237235 (Clockwise)

Preceding gene: 88607331

Following gene: 88606896

Centisome position: 16.07

GC content: 44.98

Gene sequence:

>747_bases
ATGGATGGTCTCTTACGTGGTAGGGTAGCGTTAATTACAGGTGCTTCGGGCAGTATAGGTTCGGCTGTTGCGAAGAGATA
TGCTGCAGAAGGGGCGAGTGTTGTACTCGCGTCTCGAAACGTTAGTAAGATGAAAGCTCTATATGATAGCATACAGGGCT
TAGGTGGTGACGTTATATTGGCTCCAATAGACCTAAATGATTACGAGAGTGTTGGCAATTTAGCTCTCTCCATCGAGAAT
AAATATGGCTTGCTTGATATTCTTGTGTCAGCCGCCGCTGTGTTGGGGAATTTGGCTCCTGTGCAGGAATGTGACCCCGT
CAAGTGGAAGGAAGTGATGGGCGTGAACCTGAACGCAAATTGGTACCTTATAAAGCATTTTGATGCGCTGTTAAAACAAT
CAGCAGCTGGTCGGGCTATTTTTGTTACTTCAGAAGCTACTAGGACGCTGCTAAACTACTCGTATTTTGCGCCTTATGCG
ACAAGTAAAGTTGCATTGGAGGCTTTGGTTCAAGTGTATGCAGCTGAGACGAAACATAGTAAGTTATGTGTCAATATGGT
ATATCCTGGACAGGTTGATAGTGGCATACATGTAGCCATTTTTTCAACTCAGGAGCAGTCAAAGTTTCCTTCGCCAGAAG
AGCTGACTGACAAGTTTGTCGAGCTGGCTTCACCGGAATGTACTGTTACAGGGCAGGTTTATGAACTTACAGTGGCTGAG
AAAGTAAGACAACGCTCTTTCTTATAG

Upstream 100 bases:

>100_bases
TGCGTTGCTATAACTGGGGTTGAAAGAACTATTTTGCTTGTCAATGTCCGCTATAAGAAGTACCATGCAGACTTGTGTTG
GTATGACGTGAGACTGGATT

Downstream 100 bases:

>100_bases
CAGTAAGTTTGCAGTATCTGCGCGTTTGTTGATGCTTCGTAAGATGTGTGCATGGGGGAATTGTTCTCTATGTTCCAGTG
TTTTCCAAATGTCTAAGTAG

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MDGLLRGRVALITGASGSIGSAVAKRYAAEGASVVLASRNVSKMKALYDSIQGLGGDVILAPIDLNDYESVGNLALSIEN
KYGLLDILVSAAAVLGNLAPVQECDPVKWKEVMGVNLNANWYLIKHFDALLKQSAAGRAIFVTSEATRTLLNYSYFAPYA
TSKVALEALVQVYAAETKHSKLCVNMVYPGQVDSGIHVAIFSTQEQSKFPSPEELTDKFVELASPECTVTGQVYELTVAE
KVRQRSFL

Sequences:

>Translated_248_residues
MDGLLRGRVALITGASGSIGSAVAKRYAAEGASVVLASRNVSKMKALYDSIQGLGGDVILAPIDLNDYESVGNLALSIEN
KYGLLDILVSAAAVLGNLAPVQECDPVKWKEVMGVNLNANWYLIKHFDALLKQSAAGRAIFVTSEATRTLLNYSYFAPYA
TSKVALEALVQVYAAETKHSKLCVNMVYPGQVDSGIHVAIFSTQEQSKFPSPEELTDKFVELASPECTVTGQVYELTVAE
KVRQRSFL
>Mature_248_residues
MDGLLRGRVALITGASGSIGSAVAKRYAAEGASVVLASRNVSKMKALYDSIQGLGGDVILAPIDLNDYESVGNLALSIEN
KYGLLDILVSAAAVLGNLAPVQECDPVKWKEVMGVNLNANWYLIKHFDALLKQSAAGRAIFVTSEATRTLLNYSYFAPYA
TSKVALEALVQVYAAETKHSKLCVNMVYPGQVDSGIHVAIFSTQEQSKFPSPEELTDKFVELASPECTVTGQVYELTVAE
KVRQRSFL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=222, Percent_Identity=27.4774774774775, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI19923817, Length=266, Percent_Identity=26.3157894736842, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4503817, Length=229, Percent_Identity=25.3275109170306, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787526, Length=222, Percent_Identity=31.981981981982, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787335, Length=239, Percent_Identity=25.9414225941423, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1789378, Length=255, Percent_Identity=25.4901960784314, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI2367365, Length=245, Percent_Identity=25.3061224489796, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=215, Percent_Identity=27.906976744186, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555612, Length=226, Percent_Identity=27.8761061946903, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=27.1255060728745, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=196, Percent_Identity=29.5918367346939, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355319, Length=200, Percent_Identity=29.5, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI23397609, Length=202, Percent_Identity=28.7128712871287, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45553409, Length=204, Percent_Identity=27.9411764705882, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24647948, Length=204, Percent_Identity=27.9411764705882, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24647946, Length=204, Percent_Identity=27.9411764705882, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=27.3092369477912, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281364494, Length=199, Percent_Identity=27.6381909547739, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26698; Mature: 26698

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGLLRGRVALITGASGSIGSAVAKRYAAEGASVVLASRNVSKMKALYDSIQGLGGDVIL
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEE
APIDLNDYESVGNLALSIENKYGLLDILVSAAAVLGNLAPVQECDPVKWKEVMGVNLNAN
EEECCCCHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEECCCCC
WYLIKHFDALLKQSAAGRAIFVTSEATRTLLNYSYFAPYATSKVALEALVQVYAAETKHS
EEEHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
KLCVNMVYPGQVDSGIHVAIFSTQEQSKFPSPEELTDKFVELASPECTVTGQVYELTVAE
EEEEEEEECCCCCCCEEEEEEECCHHCCCCCHHHHHHHHHHHCCCCEEEECEEEEEHHHH
KVRQRSFL
HHHHHCCC
>Mature Secondary Structure
MDGLLRGRVALITGASGSIGSAVAKRYAAEGASVVLASRNVSKMKALYDSIQGLGGDVIL
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEE
APIDLNDYESVGNLALSIENKYGLLDILVSAAAVLGNLAPVQECDPVKWKEVMGVNLNAN
EEECCCCHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEECCCCC
WYLIKHFDALLKQSAAGRAIFVTSEATRTLLNYSYFAPYATSKVALEALVQVYAAETKHS
EEEHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
KLCVNMVYPGQVDSGIHVAIFSTQEQSKFPSPEELTDKFVELASPECTVTGQVYELTVAE
EEEEEEEECCCCCCCEEEEEEECCHHCCCCCHHHHHHHHHHHCCCCEEEECEEEEEHHHH
KVRQRSFL
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1885549 [H]