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The map label for this gene is ctaA

Identifier: 88606972

GI number: 88606972

Start: 130983

End: 131969

Strand: Direct

Name: ctaA

Synonym: APH_0123

Alternate gene names: 88606972

Gene position: 130983-131969 (Clockwise)

Preceding gene: 88607395

Following gene: 88607639

Centisome position: 8.9

GC content: 42.65

Gene sequence:

>987_bases
ATGCGCACATCACACATTGCAACATGGTTAGGTACTTGTTGCATCATGGTCCTTCTTATGGTTTTTGTTGGTGGTGTGAC
GCGTCTGACAAATTCTGGATTATCTATTACTGAATGGCGCCCTGTAACTGGTGTGCTGCCCCCAATCAGTGACGCCGATT
GGGCGAAAGAACACGAGAAATACGCAAAGACCCCTGAGTATCTCTACATTAACTCTGGAATCTCACTGAGTGACTTCAAG
CGCATATACATGACAGAATATGTGCATAGATTACTGGGCAGGATTCTCGGCATTATATTCTTCGTACCTATGCTTTATTT
TGCAGTAAAAAGGCAAATCAAAGGAGCCCTGGCTGCACGACTTGGTATAGTAGCATTATTGGGCGCATTACAGGGTGCAA
TGGGATGGTTTATGGTGAAGAGTGGTCTGGTAGATGTACCTTATGTAAGCCATTTCAGGCTCGCCGCACACTTATTTCTA
ACAATTTTGCTGTTTTCTCTGCTATGGCATAGCTTTTTAGAAAGTAGAGGTGTAGTTGCAGTACATAAAGTTACACATGG
CAAATATATTTTTGCGATATTTATGCTTGTGATAACAGTGTTGCAGATGGTATTAGGTGCGTTGGTAGCTGGCTTGGACG
CTGGTCTTATCTTCAACACTTTTCCTCTAATGGATGGAGACATAATTCCGAGCCAAATACTTTCTGGAGAGCTATTAACC
GGTAAATTTCTATACAATGCAGTTGTTGTACAGTTTCTGCACCGGTTTTTTGCTACTGTTGTGCTGGTGGGAGCGGTGGC
TATACCCCTACTGATGCGATTCAAAGAGTCGTGGATGCTGTGTTTTGGTATCGTATTGCAATTTTTGTTTGGCGTGGCAA
CTTTGGTTCATGGAGTACCACTGTATCTGGCGTCTTTGCATCAAATATGGAGTTTTGTAGTAGTGGCTTTGGAGGTTTAT
ATACTGAAAGTGATCAGAAAAGTGTAG

Upstream 100 bases:

>100_bases
TGTGACTGCATTTTATGGACATGGTTTACTAGGTTAAACGACTGTTTTATTGTGAGAGATATAGGGACGGCGTTATAATT
CCGGTTTTAAAGGCAGAGAT

Downstream 100 bases:

>100_bases
CCGTACTAATGGTATAACGCGTTCCTAACACTCACGTCGTTTGTACCTGATAGAGGCTAGTATTAGATAGAAGGTGGATT
CACAAATGTTTAGCGTCCAC

Product: putative cytochrome oxidase assembly protein

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MRTSHIATWLGTCCIMVLLMVFVGGVTRLTNSGLSITEWRPVTGVLPPISDADWAKEHEKYAKTPEYLYINSGISLSDFK
RIYMTEYVHRLLGRILGIIFFVPMLYFAVKRQIKGALAARLGIVALLGALQGAMGWFMVKSGLVDVPYVSHFRLAAHLFL
TILLFSLLWHSFLESRGVVAVHKVTHGKYIFAIFMLVITVLQMVLGALVAGLDAGLIFNTFPLMDGDIIPSQILSGELLT
GKFLYNAVVVQFLHRFFATVVLVGAVAIPLLMRFKESWMLCFGIVLQFLFGVATLVHGVPLYLASLHQIWSFVVVALEVY
ILKVIRKV

Sequences:

>Translated_328_residues
MRTSHIATWLGTCCIMVLLMVFVGGVTRLTNSGLSITEWRPVTGVLPPISDADWAKEHEKYAKTPEYLYINSGISLSDFK
RIYMTEYVHRLLGRILGIIFFVPMLYFAVKRQIKGALAARLGIVALLGALQGAMGWFMVKSGLVDVPYVSHFRLAAHLFL
TILLFSLLWHSFLESRGVVAVHKVTHGKYIFAIFMLVITVLQMVLGALVAGLDAGLIFNTFPLMDGDIIPSQILSGELLT
GKFLYNAVVVQFLHRFFATVVLVGAVAIPLLMRFKESWMLCFGIVLQFLFGVATLVHGVPLYLASLHQIWSFVVVALEVY
ILKVIRKV
>Mature_328_residues
MRTSHIATWLGTCCIMVLLMVFVGGVTRLTNSGLSITEWRPVTGVLPPISDADWAKEHEKYAKTPEYLYINSGISLSDFK
RIYMTEYVHRLLGRILGIIFFVPMLYFAVKRQIKGALAARLGIVALLGALQGAMGWFMVKSGLVDVPYVSHFRLAAHLFL
TILLFSLLWHSFLESRGVVAVHKVTHGKYIFAIFMLVITVLQMVLGALVAGLDAGLIFNTFPLMDGDIIPSQILSGELLT
GKFLYNAVVVQFLHRFFATVVLVGAVAIPLLMRFKESWMLCFGIVLQFLFGVATLVHGVPLYLASLHQIWSFVVVALEVY
ILKVIRKV

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI17921985, Length=351, Percent_Identity=32.7635327635328, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI17921987, Length=328, Percent_Identity=32.6219512195122, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17536069, Length=352, Percent_Identity=34.375, Blast_Score=190, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6320989, Length=372, Percent_Identity=34.1397849462366, Blast_Score=182, Evalue=7e-47,
Organism=Drosophila melanogaster, GI19922860, Length=343, Percent_Identity=34.402332361516, Blast_Score=170, Evalue=9e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA_ANAPZ (Q2GLK1)

Other databases:

- EMBL:   CP000235
- RefSeq:   YP_504750.1
- STRING:   Q2GLK1
- GeneID:   3930040
- GenomeReviews:   CP000235_GR
- KEGG:   aph:APH_0123
- NMPDR:   fig|212042.5.peg.119
- TIGR:   APH_0123
- eggNOG:   COG1612
- HOGENOM:   HBG628966
- OMA:   PPMSEAA
- PhylomeDB:   Q2GLK1
- ProtClustDB:   CLSK2766794
- BioCyc:   APHA212042:APH_0123-MONOMER
- HAMAP:   MF_01665
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 36595; Mature: 36595

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: BINDING 307-307

Signals:

None

Transmembrane regions:

HASH(0x173de810)-; HASH(0x179ea8e8)-; HASH(0x1788eba4)-; HASH(0x17896b18)-; HASH(0x178869ac)-; HASH(0x17896dd0)-; HASH(0x1788eb14)-; HASH(0x1788e8ec)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTSHIATWLGTCCIMVLLMVFVGGVTRLTNSGLSITEWRPVTGVLPPISDADWAKEHEK
CCCHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCEECCCCCCCCCCCCCCCHHHHHHHH
YAKTPEYLYINSGISLSDFKRIYMTEYVHRLLGRILGIIFFVPMLYFAVKRQIKGALAAR
HCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGIVALLGALQGAMGWFMVKSGLVDVPYVSHFRLAAHLFLTILLFSLLWHSFLESRGVVA
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VHKVTHGKYIFAIFMLVITVLQMVLGALVAGLDAGLIFNTFPLMDGDIIPSQILSGELLT
EEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCHHHHHCCCHHH
GKFLYNAVVVQFLHRFFATVVLVGAVAIPLLMRFKESWMLCFGIVLQFLFGVATLVHGVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYLASLHQIWSFVVVALEVYILKVIRKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MRTSHIATWLGTCCIMVLLMVFVGGVTRLTNSGLSITEWRPVTGVLPPISDADWAKEHEK
CCCHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCEECCCCCCCCCCCCCCCHHHHHHHH
YAKTPEYLYINSGISLSDFKRIYMTEYVHRLLGRILGIIFFVPMLYFAVKRQIKGALAAR
HCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGIVALLGALQGAMGWFMVKSGLVDVPYVSHFRLAAHLFLTILLFSLLWHSFLESRGVVA
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VHKVTHGKYIFAIFMLVITVLQMVLGALVAGLDAGLIFNTFPLMDGDIIPSQILSGELLT
EEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCHHHHHCCCHHH
GKFLYNAVVVQFLHRFFATVVLVGAVAIPLLMRFKESWMLCFGIVLQFLFGVATLVHGVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYLASLHQIWSFVVVALEVYILKVIRKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA