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The map label for this gene is sodB [H]

Identifier: 88606849

GI number: 88606849

Start: 364302

End: 364922

Strand: Direct

Name: sodB [H]

Synonym: APH_0371

Alternate gene names: 88606849

Gene position: 364302-364922 (Clockwise)

Preceding gene: 88606988

Following gene: 88607882

Centisome position: 24.76

GC content: 43.0

Gene sequence:

>621_bases
ATGTTTGAATTGTCTGATCTGCCGTATGAGGGGTTGGAGCCGTATATTTCTTCCCATCTCTTAGATCGTCACTATAATGG
TCACCACAAAACTTATGTTGATGTTCTAAACAAGTTGGTGGTGGGTACTGAGTTTGAAGGTTTGGGTAACGAAAGCTTAG
GGGATATAGTAGTCAAGGCTCACAATAGTGGGAGTGCTGGTAGGGCTATATTCAACAATGCTGCGCAAATATGGAATCAC
GATTTCTATTGGCAATCCATGAAGCCGAATGGTGGGGGAAATCCTCCAGAGAAGCTTAGAGAGATGATAGAGCACAGTTT
CGGTAGTGTGGAAGGGTTTAATAATGCCTTTACTACTAGTGGTCTTGGGCAGTTCGGTAGTGGATGGGTATGGCTTGTAT
ATGATGAAGATGCTAAGGCATTGAAAGTTGTTAGCACAGCGAATGCAGATTCACCGCTTCTTACTCAGGGGCAGCTTCCT
TTGGCAACTATGGATGTTTGGGAGCATGCTTACTATTTAGATTATCTCAACCTAAGGAAGAAATATATAGACGTTTTCCT
AGAGCATTTGCTTAACTGGGATTTTGTCTTGGGTAGACTGGAAGATGCAGGTGTACTGTAG

Upstream 100 bases:

>100_bases
GTTGCAGTTGGCAGTTAGAAGCAGTTAATTTTTTAGTTTAATTATTGTAATTTAATAGTATAGTTGGTATAGACTGTAGT
TTACGCGGTGAGAATAAAAA

Downstream 100 bases:

>100_bases
GCTGCGTAGAAGGTTTGTAGGAATTAAAAGTTTGATAACCTTTTGTTGTTAGATTCTGTCAAAGATTGTGCGGGCCTGTT
TTCGGTTTAGTCATGTCTGG

Product: Fe superoxide dismutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MFELSDLPYEGLEPYISSHLLDRHYNGHHKTYVDVLNKLVVGTEFEGLGNESLGDIVVKAHNSGSAGRAIFNNAAQIWNH
DFYWQSMKPNGGGNPPEKLREMIEHSFGSVEGFNNAFTTSGLGQFGSGWVWLVYDEDAKALKVVSTANADSPLLTQGQLP
LATMDVWEHAYYLDYLNLRKKYIDVFLEHLLNWDFVLGRLEDAGVL

Sequences:

>Translated_206_residues
MFELSDLPYEGLEPYISSHLLDRHYNGHHKTYVDVLNKLVVGTEFEGLGNESLGDIVVKAHNSGSAGRAIFNNAAQIWNH
DFYWQSMKPNGGGNPPEKLREMIEHSFGSVEGFNNAFTTSGLGQFGSGWVWLVYDEDAKALKVVSTANADSPLLTQGQLP
LATMDVWEHAYYLDYLNLRKKYIDVFLEHLLNWDFVLGRLEDAGVL
>Mature_206_residues
MFELSDLPYEGLEPYISSHLLDRHYNGHHKTYVDVLNKLVVGTEFEGLGNESLGDIVVKAHNSGSAGRAIFNNAAQIWNH
DFYWQSMKPNGGGNPPEKLREMIEHSFGSVEGFNNAFTTSGLGQFGSGWVWLVYDEDAKALKVVSTANADSPLLTQGQLP
LATMDVWEHAYYLDYLNLRKKYIDVFLEHLLNWDFVLGRLEDAGVL

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=198, Percent_Identity=36.3636363636364, Blast_Score=124, Evalue=8e-29,
Organism=Homo sapiens, GI67782305, Length=198, Percent_Identity=36.3636363636364, Blast_Score=124, Evalue=8e-29,
Organism=Homo sapiens, GI67782309, Length=198, Percent_Identity=28.7878787878788, Blast_Score=87, Evalue=9e-18,
Organism=Escherichia coli, GI1787946, Length=201, Percent_Identity=48.7562189054726, Blast_Score=183, Evalue=9e-48,
Organism=Escherichia coli, GI1790342, Length=208, Percent_Identity=36.5384615384615, Blast_Score=117, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17506561, Length=209, Percent_Identity=36.3636363636364, Blast_Score=115, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17569479, Length=209, Percent_Identity=35.4066985645933, Blast_Score=109, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6321796, Length=215, Percent_Identity=33.953488372093, Blast_Score=96, Evalue=4e-21,
Organism=Drosophila melanogaster, GI17136812, Length=205, Percent_Identity=33.1707317073171, Blast_Score=115, Evalue=2e-26,

Paralogues:

None

Copy number: 2020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 900 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 23167; Mature: 23167

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFELSDLPYEGLEPYISSHLLDRHYNGHHKTYVDVLNKLVVGTEFEGLGNESLGDIVVKA
CCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
HNSGSAGRAIFNNAAQIWNHDFYWQSMKPNGGGNPPEKLREMIEHSFGSVEGFNNAFTTS
CCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
GLGQFGSGWVWLVYDEDAKALKVVSTANADSPLLTQGQLPLATMDVWEHAYYLDYLNLRK
CCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHH
KYIDVFLEHLLNWDFVLGRLEDAGVL
HHHHHHHHHHHCHHHHHHCCCCCCCC
>Mature Secondary Structure
MFELSDLPYEGLEPYISSHLLDRHYNGHHKTYVDVLNKLVVGTEFEGLGNESLGDIVVKA
CCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
HNSGSAGRAIFNNAAQIWNHDFYWQSMKPNGGGNPPEKLREMIEHSFGSVEGFNNAFTTS
CCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
GLGQFGSGWVWLVYDEDAKALKVVSTANADSPLLTQGQLPLATMDVWEHAYYLDYLNLRK
CCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHH
KYIDVFLEHLLNWDFVLGRLEDAGVL
HHHHHHHHHHHCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231; 9298645 [H]