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The map label for this gene is nuoC [H]

Identifier: 88606841

GI number: 88606841

Start: 535345

End: 535620

Strand: Direct

Name: nuoC [H]

Synonym: APH_0511

Alternate gene names: 88606841

Gene position: 535345-535620 (Clockwise)

Preceding gene: 88607338

Following gene: 88606734

Centisome position: 36.39

GC content: 45.65

Gene sequence:

>276_bases
ATACCTTCTGTAACTTCAGTTTTTGGATCCGCGGGGTGGTTTGAGCGCGAAGTTTACGATATGTATGGCATCGAGTTTAG
TGATCATCCTGATCTGAGGCGTATTCTCACAGACTACGGGTTTCGAGGTCACCCAATGCTAAAGGACTTTCCGCTCACGG
GTTACGAAGAGATACGATATGACTTCCGTAAAGGGAAGGTGGCATATCAGCCGGTGGATTTGCAGCAAAACTTTAGGTTA
TTCAATTCAATGTCGCCATGGAAAGGCTACAAGTAA

Upstream 100 bases:

>100_bases
AGTTTTTGCAGGGTAGTGGCTTGAGCAAAATCTTTCCTAAAGGGATACTTTTGACTCTATTACCAGATTAGCAAGGGAGG
GCATATAACAGGGAAGTATT

Downstream 100 bases:

>100_bases
TTAATGTATAACCCACTATTGCGGCAGTATAGGGTATGGCATTCTCGAATTGTTTATGCGCCATTGATACCTTATTCGCA
GTGTTGTTGCAGATAACTCA

Product: NADH dehydrogenase I, C subunit, truncation

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 91; Mature: 90

Protein sequence:

>91_residues
MPSVTSVFGSAGWFEREVYDMYGIEFSDHPDLRRILTDYGFRGHPMLKDFPLTGYEEIRYDFRKGKVAYQPVDLQQNFRL
FNSMSPWKGYK

Sequences:

>Translated_91_residues
MPSVTSVFGSAGWFEREVYDMYGIEFSDHPDLRRILTDYGFRGHPMLKDFPLTGYEEIRYDFRKGKVAYQPVDLQQNFRL
FNSMSPWKGYK
>Mature_90_residues
PSVTSVFGSAGWFEREVYDMYGIEFSDHPDLRRILTDYGFRGHPMLKDFPLTGYEEIRYDFRKGKVAYQPVDLQQNFRLF
NSMSPWKGYK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=90, Percent_Identity=56.6666666666667, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI145693162, Length=66, Percent_Identity=40.9090909090909, Blast_Score=66, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI32563621, Length=88, Percent_Identity=60.2272727272727, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71990788, Length=88, Percent_Identity=60.2272727272727, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24656494, Length=88, Percent_Identity=54.5454545454545, Blast_Score=115, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 10828; Mature: 10697

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSVTSVFGSAGWFEREVYDMYGIEFSDHPDLRRILTDYGFRGHPMLKDFPLTGYEEIRY
CCCHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
DFRKGKVAYQPVDLQQNFRLFNSMSPWKGYK
HHHCCCEEECCCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PSVTSVFGSAGWFEREVYDMYGIEFSDHPDLRRILTDYGFRGHPMLKDFPLTGYEEIRY
CCHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
DFRKGKVAYQPVDLQQNFRLFNSMSPWKGYK
HHHCCCEEECCCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA