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The map label for this gene is efp

Identifier: 87199975

GI number: 87199975

Start: 2076522

End: 2077085

Strand: Reverse

Name: efp

Synonym: Saro_1958

Alternate gene names: 87199975

Gene position: 2077085-2076522 (Counterclockwise)

Preceding gene: 87199977

Following gene: 87199974

Centisome position: 58.32

GC content: 60.46

Gene sequence:

>564_bases
ATGAAGATCAGCGGCGTGGACATCCGTCCGGGCAACATCCTGGAATACGAAAAGGGCATCTGGAAGGTCGCAAAGACCCA
GCATACCCAGCCCGGCAAGGGCGGCGCCTTCATGCAGGTCGAGATGAAGAACCTCATCGACGGCCGCAAGACCAACGTCC
GCTTCCGCAGCGCCGACACGGTCGAGCGCGTTCGCCTCGACACCAAGGATTTCCAGTTCCTCTACGCGGAAGGCGACGAT
CTGGTATTCATGGACGTCGAGACCTACGACCAGATCACCCTACCCAGCGATCTTCTCGGCGATGCCGCAGCGTTCCTGCA
GGACGGCATGACCGTCCTCCTCGAAATGTACGACGAACGCCCGATTTCCGTGCAGCTTCCGGAACAGGTCGAAGCGACCA
TTGTCGAGGCTGATGCCGTGGTTAAGGGGCAGACCGCTTCTTCGTCCTACAAACCGGCCATCCTCGATAACGGCGTGCGC
GTGATGGTTCCGCCGCACATCGAAAGCGGCACCCGCATCGTCGTCGACGTCTACGAGCGCAGCTACGTAGGCAAGGCGAA
CTGA

Upstream 100 bases:

>100_bases
CTAGCACGCGCGGTGCGGTCCGGGCAATCGGGCGCTTGAAGCAAACGGCCCGAACCGCTAAGGGCCGCCCTTCCTACTTT
AGCGCAAGGCTCTTTCCATC

Downstream 100 bases:

>100_bases
TCGATGGCAGCTATTTCCGGCCTCATTCGCGTGATGGAGCGCGCGGCGCGCAAGGCGGGTGGACGCCTGCGCCGCGACTT
CGGCGAGATCGAACATCTCC

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MKISGVDIRPGNILEYEKGIWKVAKTQHTQPGKGGAFMQVEMKNLIDGRKTNVRFRSADTVERVRLDTKDFQFLYAEGDD
LVFMDVETYDQITLPSDLLGDAAAFLQDGMTVLLEMYDERPISVQLPEQVEATIVEADAVVKGQTASSSYKPAILDNGVR
VMVPPHIESGTRIVVDVYERSYVGKAN

Sequences:

>Translated_187_residues
MKISGVDIRPGNILEYEKGIWKVAKTQHTQPGKGGAFMQVEMKNLIDGRKTNVRFRSADTVERVRLDTKDFQFLYAEGDD
LVFMDVETYDQITLPSDLLGDAAAFLQDGMTVLLEMYDERPISVQLPEQVEATIVEADAVVKGQTASSSYKPAILDNGVR
VMVPPHIESGTRIVVDVYERSYVGKAN
>Mature_187_residues
MKISGVDIRPGNILEYEKGIWKVAKTQHTQPGKGGAFMQVEMKNLIDGRKTNVRFRSADTVERVRLDTKDFQFLYAEGDD
LVFMDVETYDQITLPSDLLGDAAAFLQDGMTVLLEMYDERPISVQLPEQVEATIVEADAVVKGQTASSSYKPAILDNGVR
VMVPPHIESGTRIVVDVYERSYVGKAN

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=179, Percent_Identity=32.4022346368715, Blast_Score=104, Evalue=3e-24,
Organism=Escherichia coli, GI87082061, Length=187, Percent_Identity=31.0160427807487, Blast_Score=91, Evalue=6e-20,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_NOVAD (Q2G6X5)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_497232.1
- STRING:   Q2G6X5
- GeneID:   3917274
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_1958
- NMPDR:   fig|48935.1.peg.2666
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- PhylomeDB:   Q2G6X5
- ProtClustDB:   PRK00529
- BioCyc:   NARO279238:SARO_1958-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20831; Mature: 20831

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISGVDIRPGNILEYEKGIWKVAKTQHTQPGKGGAFMQVEMKNLIDGRKTNVRFRSADT
CCCCCEEECCCCEEEHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHCCCCCCCEEEECCCC
VERVRLDTKDFQFLYAEGDDLVFMDVETYDQITLPSDLLGDAAAFLQDGMTVLLEMYDER
HHHHCCCCCCEEEEEECCCCEEEEEECCCCCEECCHHHHHHHHHHHHCCHHEEHHHHCCC
PISVQLPEQVEATIVEADAVVKGQTASSSYKPAILDNGVRVMVPPHIESGTRIVVDVYER
CCEEECCCHHEEEEEECCEEEECCCCCCCCCCCEECCCCEEEECCCCCCCCEEEEEEECC
SYVGKAN
CCCCCCC
>Mature Secondary Structure
MKISGVDIRPGNILEYEKGIWKVAKTQHTQPGKGGAFMQVEMKNLIDGRKTNVRFRSADT
CCCCCEEECCCCEEEHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHCCCCCCCEEEECCCC
VERVRLDTKDFQFLYAEGDDLVFMDVETYDQITLPSDLLGDAAAFLQDGMTVLLEMYDER
HHHHCCCCCCEEEEEECCCCEEEEEECCCCCEECCHHHHHHHHHHHHCCHHEEHHHHCCC
PISVQLPEQVEATIVEADAVVKGQTASSSYKPAILDNGVRVMVPPHIESGTRIVVDVYER
CCEEECCCHHEEEEEECCEEEECCCCCCCCCCCEECCCCEEEECCCCCCCCEEEEEEECC
SYVGKAN
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA