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The map label for this gene is alr [H]

Identifier: 87199969

GI number: 87199969

Start: 2070281

End: 2071351

Strand: Reverse

Name: alr [H]

Synonym: Saro_1952

Alternate gene names: 87199969

Gene position: 2071351-2070281 (Counterclockwise)

Preceding gene: 87199970

Following gene: 87199968

Centisome position: 58.16

GC content: 64.8

Gene sequence:

>1071_bases
ATGACTGACATTTCCCTTCCGACGACGCCCGACCTGCCCGAGTCCTCCCTTCGCCTGCGGATCGATGCCGATGCGCTTGC
GTCTAACTGGCGCGCACTCGACGCGATGTCGGGCACGGCGACCGCCGGCGCTGCAGTAAAGGCTGATGCCTATGGACTGG
GCGCTGCGCGTGTCTCGCGCATCCTTGTCGGCGCGGGTTGTCGCGACTTCTTCGTCGCGCATTGGGCGGAAGTGCCGAAC
CTCCTGCCGCATGTCCCCGCAGCCAGCATCGCCGTGCTGCATGGTCCCATGAATGCGGCGGAAGCCGCCTTCGCTCGGGC
AACTGGTGCAAGGCCAGTTCTGAACAGCCTGTCGCAGGCCCGTCTCTGGCAGGAAACAGGCGGCGGACGGTGCCACGTCA
TGGTCGATACCGGAATGAGTCGACTTGGCCTCGCCATGTCCGAGATCGCCGATCCAGCGCTGGCTGACCTCGATGTGGAC
CTTTGCCTCAGCCACCTCGCAAGTGCGGATGAGGATGTTCCGCAGAACGAGCAACAGCGCCTTCGCTTCGAAACGGTCCG
CGCCGCCATTCCCGCCCGTCGCTACAGCCTTGCCAACAGCGCCGGCATAGCGCTCGGTGCGGGCTTCCACGCGGACGTCA
CTCGCCCGGGCATCGCTCTCTATGGCGGCATCGCCAGGCCCGAATTTGCCGGCACGATCCGCCAGGTCGCGCGTCCCGAA
GCAGCGGTCATCCAGGTCCGCCATCTCCAACCAGGCGACAAAGTCGGCTACAATGCGATCTTTACCGCTGATCGCCCGAT
GCGGGTCGGCGTTCTCGCGATCGGCTATGCCGACGGCTATCTTCGCTGCTGGACCGGGCGGGGTAGCTTCCTGTTCGATG
GAGTCGAAGTACCCGTCCTCGGCCGGGTGTCTATGGACCTCACCATCGTCGACCTTGGCGGAGTCCCGTCATGCAACGAG
GGGGATTGGCTGGTCGCATCCTACGACTTGCCGCGCGCAGCGCGCGAAAGCGGCCTTTCGCAGTACGAACTGCTTACGGT
GCTGGGGCGTAGATTTTCCCGCCGGAATTGA

Upstream 100 bases:

>100_bases
GATCCCTATGCCGGGCTATGGTACACTTGGGTGGTCGTCCTGGTCGCGCTCCTCGTTGCGGCGTGGGGTTTGCGGCCAGG
CCTGCCCGCCGACTTCACGG

Downstream 100 bases:

>100_bases
ATCTAAACCATTTGTCGAGACTTGTTGCGCCGCACATACTGCACATGCTAATAGTAGAAATGTCGCAGTGGGGGCGCACG
TCATGGCAAATGAAGGCAAG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTDISLPTTPDLPESSLRLRIDADALASNWRALDAMSGTATAGAAVKADAYGLGAARVSRILVGAGCRDFFVAHWAEVPN
LLPHVPAASIAVLHGPMNAAEAAFARATGARPVLNSLSQARLWQETGGGRCHVMVDTGMSRLGLAMSEIADPALADLDVD
LCLSHLASADEDVPQNEQQRLRFETVRAAIPARRYSLANSAGIALGAGFHADVTRPGIALYGGIARPEFAGTIRQVARPE
AAVIQVRHLQPGDKVGYNAIFTADRPMRVGVLAIGYADGYLRCWTGRGSFLFDGVEVPVLGRVSMDLTIVDLGGVPSCNE
GDWLVASYDLPRAARESGLSQYELLTVLGRRFSRRN

Sequences:

>Translated_356_residues
MTDISLPTTPDLPESSLRLRIDADALASNWRALDAMSGTATAGAAVKADAYGLGAARVSRILVGAGCRDFFVAHWAEVPN
LLPHVPAASIAVLHGPMNAAEAAFARATGARPVLNSLSQARLWQETGGGRCHVMVDTGMSRLGLAMSEIADPALADLDVD
LCLSHLASADEDVPQNEQQRLRFETVRAAIPARRYSLANSAGIALGAGFHADVTRPGIALYGGIARPEFAGTIRQVARPE
AAVIQVRHLQPGDKVGYNAIFTADRPMRVGVLAIGYADGYLRCWTGRGSFLFDGVEVPVLGRVSMDLTIVDLGGVPSCNE
GDWLVASYDLPRAARESGLSQYELLTVLGRRFSRRN
>Mature_355_residues
TDISLPTTPDLPESSLRLRIDADALASNWRALDAMSGTATAGAAVKADAYGLGAARVSRILVGAGCRDFFVAHWAEVPNL
LPHVPAASIAVLHGPMNAAEAAFARATGARPVLNSLSQARLWQETGGGRCHVMVDTGMSRLGLAMSEIADPALADLDVDL
CLSHLASADEDVPQNEQQRLRFETVRAAIPARRYSLANSAGIALGAGFHADVTRPGIALYGGIARPEFAGTIRQVARPEA
AVIQVRHLQPGDKVGYNAIFTADRPMRVGVLAIGYADGYLRCWTGRGSFLFDGVEVPVLGRVSMDLTIVDLGGVPSCNEG
DWLVASYDLPRAARESGLSQYELLTVLGRRFSRRN

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=358, Percent_Identity=31.8435754189944, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1787439, Length=357, Percent_Identity=29.4117647058824, Blast_Score=96, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 37857; Mature: 37725

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDISLPTTPDLPESSLRLRIDADALASNWRALDAMSGTATAGAAVKADAYGLGAARVSR
CCCCCCCCCCCCCCCCEEEEEEHHHHHCCCHHHHCCCCCCCCCCEEECCCCCCCHHHHHH
ILVGAGCRDFFVAHWAEVPNLLPHVPAASIAVLHGPMNAAEAAFARATGARPVLNSLSQA
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCCCHHHHHHHHH
RLWQETGGGRCHVMVDTGMSRLGLAMSEIADPALADLDVDLCLSHLASADEDVPQNEQQR
HHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHCCHHHHHHHHHCCCCCCCCCHHHH
LRFETVRAAIPARRYSLANSAGIALGAGFHADVTRPGIALYGGIARPEFAGTIRQVARPE
HHHHHHHHHHCHHHHHCCCCCCEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCC
AAVIQVRHLQPGDKVGYNAIFTADRPMRVGVLAIGYADGYLRCWTGRGSFLFDGVEVPVL
EEEEEEEECCCCCCCCCEEEEECCCCEEEEEEEEEECCCEEEEEECCCCEEECCCCCCEE
GRVSMDLTIVDLGGVPSCNEGDWLVASYDLPRAARESGLSQYELLTVLGRRFSRRN
EEEEEEEEEEECCCCCCCCCCCEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDISLPTTPDLPESSLRLRIDADALASNWRALDAMSGTATAGAAVKADAYGLGAARVSR
CCCCCCCCCCCCCCCEEEEEEHHHHHCCCHHHHCCCCCCCCCCEEECCCCCCCHHHHHH
ILVGAGCRDFFVAHWAEVPNLLPHVPAASIAVLHGPMNAAEAAFARATGARPVLNSLSQA
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCCCHHHHHHHHH
RLWQETGGGRCHVMVDTGMSRLGLAMSEIADPALADLDVDLCLSHLASADEDVPQNEQQR
HHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHCCHHHHHHHHHCCCCCCCCCHHHH
LRFETVRAAIPARRYSLANSAGIALGAGFHADVTRPGIALYGGIARPEFAGTIRQVARPE
HHHHHHHHHHCHHHHHCCCCCCEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCC
AAVIQVRHLQPGDKVGYNAIFTADRPMRVGVLAIGYADGYLRCWTGRGSFLFDGVEVPVL
EEEEEEEECCCCCCCCCEEEEECCCCEEEEEEEEEECCCEEEEEECCCCEEECCCCCCEE
GRVSMDLTIVDLGGVPSCNEGDWLVASYDLPRAARESGLSQYELLTVLGRRFSRRN
EEEEEEEEEEECCCCCCCCCCCEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]