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The map label for this gene is pamO [H]

Identifier: 87199548

GI number: 87199548

Start: 1573114

End: 1574736

Strand: Reverse

Name: pamO [H]

Synonym: Saro_1530

Alternate gene names: 87199548

Gene position: 1574736-1573114 (Counterclockwise)

Preceding gene: 87199549

Following gene: 87199547

Centisome position: 44.21

GC content: 58.16

Gene sequence:

>1623_bases
ATGCAACAGGTAAATAGCTCGCACGCGAAGGCACCTCGCCGCCTCGACACGCTGATCATCGGTGCTGGTTTCGGCGGCAT
GTATGCCTTGCACCGTACGCGCAACATGGGGCTTGATACTCACCTGATCGAAGCGGGCGACGATGTCGGCGGTACCTGGT
ACTGGAACCGCTACCCGGGCGCGCGCTGCGACGTGATGTGCATCGACTACAGCTACTCTTTCTCGGACGATATCCAGCAA
GAGTGGGCATGGAGCGAGCAATTCGCCGCGCAGCCCGAAATCCTCGCGTATGCGCGCTTCGTCGCCGACAAACTGGACCT
GAAGCGCGACATAAGCTTCAACACGCGCGCCACCTCGGTGCGCTATGATGACGAGAGGACATTGTGGCGGGTCCAAACCG
ATTGCGGCGATGTGTTCGAAGCCAAATATTGCCTTATGGCCACCGGGCCACTTTCCGTTCCGAAGCAGCTTGATCTTCCA
GGCACAAGCACCTTCAAGGGCGCGATCTACCTGTCGGGAAAGTGGCCTCACCACGATGTCGATCTGAAGGGCAAGCGAGT
TGCGGTAATCGGTACGGGATCATCGGGTATCCAGATCGTCCCCGTCGTTGCCGAACAGGCGGAGCATCTGTACGTTTATC
AGCGGACGCCGAGCTTTACATTGCCGATGCGCAATCGAAAGCTTGAGGAAGACTATGTTGCCCATATCAAGGCCCATTAT
CCGGGGCTTCGCAAGGCGGCCCGGCACTCGATGACCGGAGGGATTCGGCCGATTACCCATCGTCCGCTTTTCAGCGTCAC
ACCCGCAGAACGGGAAAAGCTGATGGAAGAAGCCTGGCAACGCGGCGGCTCCCACTTTCTCGGCCTCTTTTCAGACTTGC
TCACGAACAGCGAAGCCAACGAAGTCGTTGCAGAGTTCGTGCGTGGGAAGATTGCAGAGGTCGTCAATGACCCTGACACG
GCGCGCCGCCTTACCCCCCGCGGGTACCCGATTTTCGCTCGGCGCCCTTGCCTGGATACCGGGTACTACGAGACCTATAA
CCGGGAAAACGTCACGCTGAAGGATTGCCTGGAGCATCCGATCATCGAGATTACCGAAAACGGAATCCGCACCGCCGATG
GTGTGGTGGAGGTGGACGTCATCATCGCCGCCATCGGCTACGACGCACTTACCGGCGCGATGCTGTCAATCGACATTGAA
GGCAAGGAAGGTCGTAGCCTGAAAGACAAGTGGGCTGACGGCGGGCGCTCGCATGTTGGCCTCATGATCGAAGGCTTCCC
CAACCTCTTCCTGATCTCTGGCCCCAACGGTCCATCTGCGTTGGCCAATTTCATCCTGCTCGCCGAACAAAATGTCGACT
GGATATGCGACTGCATTCGACACCTGGACGCCAACGGACTGCGATCGATCGAAGCAGATGCCGGTGCCGAAAACTGGTGG
ATGAACAAGGTAACGACGCTGGGATCCATGACCCTCTATCCAACCGCCAATACTTGGTACACGGGTGCAAATGTGCCGGG
CAAGCCGCGCACTTTTCCGGTCTATGTCGGCGGTTTGGGGCGTTATCGTGAAATTTGCGACGATGCGGCAGCCCAGGGGT
ATAGCGGCTTTACGTTGAAGTGA

Upstream 100 bases:

>100_bases
GACTGAGTCGCACCCCGCAACCTTACCCGCGCGTCGCTGCACTAGCCGGACGCTTTCCAGCGCCACGGGATCAGTTCCCG
AACTACCCCAAGGATGTTCT

Downstream 100 bases:

>100_bases
AAAATCATCTCTCCGTCCAAAGGGAGATGCCCCACTTCGATATCCATCCCTTCTGACAATCTAGAATATTTATAATTCAA
TATAATTAACGAATAAATAA

Product: flavin-containing monooxygenase FMO

Products: NA

Alternate protein names: PAMO; Baeyer-Villiger monooxygenase; BVMO [H]

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MQQVNSSHAKAPRRLDTLIIGAGFGGMYALHRTRNMGLDTHLIEAGDDVGGTWYWNRYPGARCDVMCIDYSYSFSDDIQQ
EWAWSEQFAAQPEILAYARFVADKLDLKRDISFNTRATSVRYDDERTLWRVQTDCGDVFEAKYCLMATGPLSVPKQLDLP
GTSTFKGAIYLSGKWPHHDVDLKGKRVAVIGTGSSGIQIVPVVAEQAEHLYVYQRTPSFTLPMRNRKLEEDYVAHIKAHY
PGLRKAARHSMTGGIRPITHRPLFSVTPAEREKLMEEAWQRGGSHFLGLFSDLLTNSEANEVVAEFVRGKIAEVVNDPDT
ARRLTPRGYPIFARRPCLDTGYYETYNRENVTLKDCLEHPIIEITENGIRTADGVVEVDVIIAAIGYDALTGAMLSIDIE
GKEGRSLKDKWADGGRSHVGLMIEGFPNLFLISGPNGPSALANFILLAEQNVDWICDCIRHLDANGLRSIEADAGAENWW
MNKVTTLGSMTLYPTANTWYTGANVPGKPRTFPVYVGGLGRYREICDDAAAQGYSGFTLK

Sequences:

>Translated_540_residues
MQQVNSSHAKAPRRLDTLIIGAGFGGMYALHRTRNMGLDTHLIEAGDDVGGTWYWNRYPGARCDVMCIDYSYSFSDDIQQ
EWAWSEQFAAQPEILAYARFVADKLDLKRDISFNTRATSVRYDDERTLWRVQTDCGDVFEAKYCLMATGPLSVPKQLDLP
GTSTFKGAIYLSGKWPHHDVDLKGKRVAVIGTGSSGIQIVPVVAEQAEHLYVYQRTPSFTLPMRNRKLEEDYVAHIKAHY
PGLRKAARHSMTGGIRPITHRPLFSVTPAEREKLMEEAWQRGGSHFLGLFSDLLTNSEANEVVAEFVRGKIAEVVNDPDT
ARRLTPRGYPIFARRPCLDTGYYETYNRENVTLKDCLEHPIIEITENGIRTADGVVEVDVIIAAIGYDALTGAMLSIDIE
GKEGRSLKDKWADGGRSHVGLMIEGFPNLFLISGPNGPSALANFILLAEQNVDWICDCIRHLDANGLRSIEADAGAENWW
MNKVTTLGSMTLYPTANTWYTGANVPGKPRTFPVYVGGLGRYREICDDAAAQGYSGFTLK
>Mature_540_residues
MQQVNSSHAKAPRRLDTLIIGAGFGGMYALHRTRNMGLDTHLIEAGDDVGGTWYWNRYPGARCDVMCIDYSYSFSDDIQQ
EWAWSEQFAAQPEILAYARFVADKLDLKRDISFNTRATSVRYDDERTLWRVQTDCGDVFEAKYCLMATGPLSVPKQLDLP
GTSTFKGAIYLSGKWPHHDVDLKGKRVAVIGTGSSGIQIVPVVAEQAEHLYVYQRTPSFTLPMRNRKLEEDYVAHIKAHY
PGLRKAARHSMTGGIRPITHRPLFSVTPAEREKLMEEAWQRGGSHFLGLFSDLLTNSEANEVVAEFVRGKIAEVVNDPDT
ARRLTPRGYPIFARRPCLDTGYYETYNRENVTLKDCLEHPIIEITENGIRTADGVVEVDVIIAAIGYDALTGAMLSIDIE
GKEGRSLKDKWADGGRSHVGLMIEGFPNLFLISGPNGPSALANFILLAEQNVDWICDCIRHLDANGLRSIEADAGAENWW
MNKVTTLGSMTLYPTANTWYTGANVPGKPRTFPVYVGGLGRYREICDDAAAQGYSGFTLK

Specific function: Catalyzes a Baeyer-Villiger oxidation reaction, i.e., the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Is most efficient with phenylacetone as substrate, leading to the formation of benzyl

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503755, Length=216, Percent_Identity=27.3148148148148, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI4503757, Length=215, Percent_Identity=27.4418604651163, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI19922866, Length=216, Percent_Identity=25.9259259259259, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: =1.14.13.92 [H]

Molecular weight: Translated: 60163; Mature: 60163

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQVNSSHAKAPRRLDTLIIGAGFGGMYALHRTRNMGLDTHLIEAGDDVGGTWYWNRYPG
CCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCCC
ARCDVMCIDYSYSFSDDIQQEWAWSEQFAAQPEILAYARFVADKLDLKRDISFNTRATSV
CCEEEEEEEECCCCCHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEE
RYDDERTLWRVQTDCGDVFEAKYCLMATGPLSVPKQLDLPGTSTFKGAIYLSGKWPHHDV
EECCCCEEEEEECCCCCHHHCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCC
DLKGKRVAVIGTGSSGIQIVPVVAEQAEHLYVYQRTPSFTLPMRNRKLEEDYVAHIKAHY
CCCCCEEEEEECCCCCCEEEEEEECCCCEEEEEECCCCEECCCCCCCCCHHHHHHHHHCC
PGLRKAARHSMTGGIRPITHRPLFSVTPAEREKLMEEAWQRGGSHFLGLFSDLLTNSEAN
CHHHHHHHHHHCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHH
EVVAEFVRGKIAEVVNDPDTARRLTPRGYPIFARRPCLDTGYYETYNRENVTLKDCLEHP
HHHHHHHHHHHHHHHCCCHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHCCC
IIEITENGIRTADGVVEVDVIIAAIGYDALTGAMLSIDIEGKEGRSLKDKWADGGRSHVG
CEEEECCCCCCCCCEEEEEEEEEECCHHHHCCEEEEEEECCCCCCCHHHHHCCCCCCEEE
LMIEGFPNLFLISGPNGPSALANFILLAEQNVDWICDCIRHLDANGLRSIEADAGAENWW
EEEECCCCEEEEECCCCHHHHHHEEEEECCCHHHHHHHHHHCCCCCCCEECCCCCCCHHH
MNKVTTLGSMTLYPTANTWYTGANVPGKPRTFPVYVGGLGRYREICDDAAAQGYSGFTLK
HHHHHHHCCEEEEECCCCEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQQVNSSHAKAPRRLDTLIIGAGFGGMYALHRTRNMGLDTHLIEAGDDVGGTWYWNRYPG
CCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCCC
ARCDVMCIDYSYSFSDDIQQEWAWSEQFAAQPEILAYARFVADKLDLKRDISFNTRATSV
CCEEEEEEEECCCCCHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEE
RYDDERTLWRVQTDCGDVFEAKYCLMATGPLSVPKQLDLPGTSTFKGAIYLSGKWPHHDV
EECCCCEEEEEECCCCCHHHCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCC
DLKGKRVAVIGTGSSGIQIVPVVAEQAEHLYVYQRTPSFTLPMRNRKLEEDYVAHIKAHY
CCCCCEEEEEECCCCCCEEEEEEECCCCEEEEEECCCCEECCCCCCCCCHHHHHHHHHCC
PGLRKAARHSMTGGIRPITHRPLFSVTPAEREKLMEEAWQRGGSHFLGLFSDLLTNSEAN
CHHHHHHHHHHCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHH
EVVAEFVRGKIAEVVNDPDTARRLTPRGYPIFARRPCLDTGYYETYNRENVTLKDCLEHP
HHHHHHHHHHHHHHHCCCHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHCCC
IIEITENGIRTADGVVEVDVIIAAIGYDALTGAMLSIDIEGKEGRSLKDKWADGGRSHVG
CEEEECCCCCCCCCEEEEEEEEEECCHHHHCCEEEEEEECCCCCCCHHHHHCCCCCCEEE
LMIEGFPNLFLISGPNGPSALANFILLAEQNVDWICDCIRHLDANGLRSIEADAGAENWW
EEEECCCCEEEEECCCCHHHHHHEEEEECCCHHHHHHHHHHCCCCCCCEECCCCCCCHHH
MNKVTTLGSMTLYPTANTWYTGANVPGKPRTFPVYVGGLGRYREICDDAAAQGYSGFTLK
HHHHHHHCCEEEEECCCCEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA