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The map label for this gene is paaG [C]

Identifier: 87199093

GI number: 87199093

Start: 1115540

End: 1116412

Strand: Direct

Name: paaG [C]

Synonym: Saro_1071

Alternate gene names: 87199093

Gene position: 1115540-1116412 (Clockwise)

Preceding gene: 87199092

Following gene: 87199094

Centisome position: 31.32

GC content: 64.72

Gene sequence:

>873_bases
TTGGCCGAATACAAGCAGATCACGCTCGAAATTGCCGACGGCATCGCGACCCTGACGTTGCACCGGCCGGACAAGATGAA
CGCCTTCACCGGCACGATGATGAACGAGATGATCGACGCGTTCGACCGTACCGACGCCGATGACAGCGTCAGGGCGGTGA
TCGTCACCGGATCGGGCGACCGTGCCTTCTGCGCGGGCGCGGACCTTACTCCTGACGACGGCAAGCATGTGTTTTCCAGC
GGCGAGGCGGTGGAAGATCTGTCCGACCCGCGCGTGCGCGACGGCGGCGGCCTCCTGACGCTGCGCATCTACCAGTCGAA
GAAGCCTGTGATCGGTGCGATCAACGGCGCCGCGGTTGGCGTGGGCGTGACCATGCAGTTGCCGATGGACATGCGCCTTG
CATCGACGAAGGCGCGGTTCGGCCTGGTCTTCGCGCGGCGCGGGATCGTGCCGGAAGCGGCTTCGAGCTGGTTTCTGCCG
CGCATCGTGGGTCTGCCGCAGGCGCTCGAGTGGTGCATGACCGGGCGCGTGTTCGACGCCGAGGAAGCGCTGCGCGGCGG
TCTCGTGCGTTCGCTCCACGAACCCGAAGACCTGATGCCCGCAGCCCGTGCCCTTGCTCGCGAGATCGCGGACAATACCA
GCGCCGTCTCGGTCGCGATGACCCGCGCGATGCTGTGGCACAATCCGAGCCTTTCGCATCCGATGGAAGCCCACCGGGTT
GACAGTCGGGCGATCTATACGCTTTCGCGCGGCAAGGACGCGGCGGAGGGCATTACCAGCTTTCTCGAAAAGCGCGCTCC
CAGCTACCCCGGACGCGTTTCTTCGGATATGCCGTCGTTTTATCCATGGTGGGATGAGCCAGGTTGGAAATGA

Upstream 100 bases:

>100_bases
GTCCGTCTCGACGGCGCCATCCGCATGGCGCCGCGCTGATGTTTTGATGCGATGAGGGGCGGGGCAGTGCATCCCGCCCC
CATCGAACGGGAGAGGTCAT

Downstream 100 bases:

>100_bases
GTTCAGACGTGCAGAAGGGTGACAACCTCGAGACGCCGGGCGCGCGCGATCTGCTGTTGCAGACGGCGTCGAACATCATG
CGCGAAGGCGATGTCGTGGA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MAEYKQITLEIADGIATLTLHRPDKMNAFTGTMMNEMIDAFDRTDADDSVRAVIVTGSGDRAFCAGADLTPDDGKHVFSS
GEAVEDLSDPRVRDGGGLLTLRIYQSKKPVIGAINGAAVGVGVTMQLPMDMRLASTKARFGLVFARRGIVPEAASSWFLP
RIVGLPQALEWCMTGRVFDAEEALRGGLVRSLHEPEDLMPAARALAREIADNTSAVSVAMTRAMLWHNPSLSHPMEAHRV
DSRAIYTLSRGKDAAEGITSFLEKRAPSYPGRVSSDMPSFYPWWDEPGWK

Sequences:

>Translated_290_residues
MAEYKQITLEIADGIATLTLHRPDKMNAFTGTMMNEMIDAFDRTDADDSVRAVIVTGSGDRAFCAGADLTPDDGKHVFSS
GEAVEDLSDPRVRDGGGLLTLRIYQSKKPVIGAINGAAVGVGVTMQLPMDMRLASTKARFGLVFARRGIVPEAASSWFLP
RIVGLPQALEWCMTGRVFDAEEALRGGLVRSLHEPEDLMPAARALAREIADNTSAVSVAMTRAMLWHNPSLSHPMEAHRV
DSRAIYTLSRGKDAAEGITSFLEKRAPSYPGRVSSDMPSFYPWWDEPGWK
>Mature_289_residues
AEYKQITLEIADGIATLTLHRPDKMNAFTGTMMNEMIDAFDRTDADDSVRAVIVTGSGDRAFCAGADLTPDDGKHVFSSG
EAVEDLSDPRVRDGGGLLTLRIYQSKKPVIGAINGAAVGVGVTMQLPMDMRLASTKARFGLVFARRGIVPEAASSWFLPR
IVGLPQALEWCMTGRVFDAEEALRGGLVRSLHEPEDLMPAARALAREIADNTSAVSVAMTRAMLWHNPSLSHPMEAHRVD
SRAIYTLSRGKDAAEGITSFLEKRAPSYPGRVSSDMPSFYPWWDEPGWK

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=262, Percent_Identity=29.3893129770992, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI68989263, Length=214, Percent_Identity=27.1028037383178, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4502327, Length=260, Percent_Identity=30.3846153846154, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI260274832, Length=191, Percent_Identity=31.9371727748691, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI45643119, Length=191, Percent_Identity=31.9371727748691, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI260275230, Length=191, Percent_Identity=31.9371727748691, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI221136756, Length=268, Percent_Identity=26.1194029850746, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI221136753, Length=268, Percent_Identity=26.1194029850746, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI221307494, Length=268, Percent_Identity=26.1194029850746, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4757968, Length=268, Percent_Identity=26.865671641791, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI49355787, Length=268, Percent_Identity=26.865671641791, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4757966, Length=268, Percent_Identity=26.1194029850746, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI51538581, Length=268, Percent_Identity=26.1194029850746, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI25453481, Length=268, Percent_Identity=26.1194029850746, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI51538573, Length=268, Percent_Identity=26.1194029850746, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI37594471, Length=194, Percent_Identity=25.2577319587629, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI31542718, Length=267, Percent_Identity=27.3408239700375, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI37594469, Length=194, Percent_Identity=25.2577319587629, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI20127408, Length=193, Percent_Identity=25.3886010362694, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI70995211, Length=220, Percent_Identity=30.9090909090909, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI116235487, Length=275, Percent_Identity=25.8181818181818, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI1787660, Length=279, Percent_Identity=30.8243727598566, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI221142681, Length=264, Percent_Identity=34.469696969697, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787659, Length=260, Percent_Identity=31.1538461538462, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788597, Length=259, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790281, Length=244, Percent_Identity=26.2295081967213, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788682, Length=199, Percent_Identity=28.1407035175879, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI87082183, Length=275, Percent_Identity=21.8181818181818, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=265, Percent_Identity=31.3207547169811, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17549921, Length=213, Percent_Identity=34.2723004694836, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI25145438, Length=259, Percent_Identity=29.3436293436293, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17560910, Length=250, Percent_Identity=29.2, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17540714, Length=182, Percent_Identity=32.967032967033, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17535521, Length=269, Percent_Identity=26.3940520446097, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17540306, Length=248, Percent_Identity=27.0161290322581, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17534483, Length=250, Percent_Identity=28, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17558304, Length=184, Percent_Identity=27.7173913043478, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI25144276, Length=193, Percent_Identity=27.979274611399, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508953, Length=193, Percent_Identity=27.979274611399, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17508951, Length=193, Percent_Identity=27.979274611399, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20129971, Length=274, Percent_Identity=28.1021897810219, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24653477, Length=274, Percent_Identity=28.1021897810219, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24653139, Length=262, Percent_Identity=31.6793893129771, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI19920382, Length=226, Percent_Identity=32.7433628318584, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21357171, Length=188, Percent_Identity=30.8510638297872, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24654903, Length=199, Percent_Identity=26.6331658291457, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 31627; Mature: 31496

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEYKQITLEIADGIATLTLHRPDKMNAFTGTMMNEMIDAFDRTDADDSVRAVIVTGSGD
CCCHHEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCC
RAFCAGADLTPDDGKHVFSSGEAVEDLSDPRVRDGGGLLTLRIYQSKKPVIGAINGAAVG
CEEEECCCCCCCCCCHHHCCCCHHHHCCCCCEECCCCEEEEEEECCCCCEEEECCCCEEE
VGVTMQLPMDMRLASTKARFGLVFARRGIVPEAASSWFLPRIVGLPQALEWCMTGRVFDA
EEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHCCHHHHHHHHCCCEECH
EEALRGGLVRSLHEPEDLMPAARALAREIADNTSAVSVAMTRAMLWHNPSLSHPMEAHRV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHC
DSRAIYTLSRGKDAAEGITSFLEKRAPSYPGRVSSDMPSFYPWWDEPGWK
CCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AEYKQITLEIADGIATLTLHRPDKMNAFTGTMMNEMIDAFDRTDADDSVRAVIVTGSGD
CCHHEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCC
RAFCAGADLTPDDGKHVFSSGEAVEDLSDPRVRDGGGLLTLRIYQSKKPVIGAINGAAVG
CEEEECCCCCCCCCCHHHCCCCHHHHCCCCCEECCCCEEEEEEECCCCCEEEECCCCEEE
VGVTMQLPMDMRLASTKARFGLVFARRGIVPEAASSWFLPRIVGLPQALEWCMTGRVFDA
EEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHCCHHHHHHHHCCCEECH
EEALRGGLVRSLHEPEDLMPAARALAREIADNTSAVSVAMTRAMLWHNPSLSHPMEAHRV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHC
DSRAIYTLSRGKDAAEGITSFLEKRAPSYPGRVSSDMPSFYPWWDEPGWK
CCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA