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The map label for this gene is yfkJ [H]

Identifier: 87199069

GI number: 87199069

Start: 1086525

End: 1086989

Strand: Direct

Name: yfkJ [H]

Synonym: Saro_1047

Alternate gene names: 87199069

Gene position: 1086525-1086989 (Clockwise)

Preceding gene: 87199068

Following gene: 87199075

Centisome position: 30.51

GC content: 70.32

Gene sequence:

>465_bases
GTGAGCCAGCCTTCAGTACTGTTCGTGTGTCTTGGCAATATCTGCCGCTCCCCGCTGGCCGAGGCGGCCCTGCGCGCGCG
CGCCTGGGAGGCGGGGGTTGCCGTGACGGTGGATTCCGCAGGCACCGGAGACTGGCACGTCGGTCGCCCGCCCGATCCGC
GCGCGCAGGCGGTGGCCCTGGCGAACGGCCTCGACATTTCGGGGTACCGCGCGCGGCAGGTGGCGGCGGAGGACTTCGCC
CGCTTCGGGCACATCTTCGCGCTCGATCCGCAGAACCTCAAGGATCTGCGCCGCATCCAGCCGGCGCGCGCCGTTGCCGA
GGTGGGCTTGCTCATGGACATCGTCCCGGGGCGCAAGGGTACGGCGGTGATCGACCCCTACTACGGCGACGAGCAGGATT
TCGAGCAGGCATGGGCCGACGTGAGCAGCGCGGCCGAGCAGATCGTCCGGCGGTTCCTGCGCTAA

Upstream 100 bases:

>100_bases
GGCTGGACATTTCGTCGCGCGCGGTGTTTGCTGCGCGGCAGGGAGAGGATCCGTTCCTGATCGGCATGGGCAGACCCAGC
CAGCGAGGTATCGTGATCCC

Downstream 100 bases:

>100_bases
GGCCGTAAACTCATGAATGGCACCATTCCGGCGTCCCTGCGGGATTTGACCAAAACGGCCATCTGCCGCGTCAGTCGGGC
TTGAAATATCGACATATTCC

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MSQPSVLFVCLGNICRSPLAEAALRARAWEAGVAVTVDSAGTGDWHVGRPPDPRAQAVALANGLDISGYRARQVAAEDFA
RFGHIFALDPQNLKDLRRIQPARAVAEVGLLMDIVPGRKGTAVIDPYYGDEQDFEQAWADVSSAAEQIVRRFLR

Sequences:

>Translated_154_residues
MSQPSVLFVCLGNICRSPLAEAALRARAWEAGVAVTVDSAGTGDWHVGRPPDPRAQAVALANGLDISGYRARQVAAEDFA
RFGHIFALDPQNLKDLRRIQPARAVAEVGLLMDIVPGRKGTAVIDPYYGDEQDFEQAWADVSSAAEQIVRRFLR
>Mature_153_residues
SQPSVLFVCLGNICRSPLAEAALRARAWEAGVAVTVDSAGTGDWHVGRPPDPRAQAVALANGLDISGYRARQVAAEDFAR
FGHIFALDPQNLKDLRRIQPARAVAEVGLLMDIVPGRKGTAVIDPYYGDEQDFEQAWADVSSAAEQIVRRFLR

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI6005988, Length=138, Percent_Identity=43.4782608695652, Blast_Score=117, Evalue=4e-27,
Organism=Homo sapiens, GI4757714, Length=138, Percent_Identity=43.4782608695652, Blast_Score=112, Evalue=1e-25,
Organism=Homo sapiens, GI96304457, Length=77, Percent_Identity=46.7532467532467, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6325330, Length=154, Percent_Identity=34.4155844155844, Blast_Score=113, Evalue=1e-26,
Organism=Drosophila melanogaster, GI78706766, Length=152, Percent_Identity=38.1578947368421, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI78706768, Length=152, Percent_Identity=38.1578947368421, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI78706764, Length=125, Percent_Identity=42.4, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI78706770, Length=152, Percent_Identity=38.8157894736842, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI78706772, Length=152, Percent_Identity=38.8157894736842, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI78711846, Length=153, Percent_Identity=33.9869281045752, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24648069, Length=153, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16730; Mature: 16599

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPSVLFVCLGNICRSPLAEAALRARAWEAGVAVTVDSAGTGDWHVGRPPDPRAQAVAL
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCHHHHHHH
ANGLDISGYRARQVAAEDFARFGHIFALDPQNLKDLRRIQPARAVAEVGLLMDIVPGRKG
HCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TAVIDPYYGDEQDFEQAWADVSSAAEQIVRRFLR
CEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SQPSVLFVCLGNICRSPLAEAALRARAWEAGVAVTVDSAGTGDWHVGRPPDPRAQAVAL
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCHHHHHHH
ANGLDISGYRARQVAAEDFARFGHIFALDPQNLKDLRRIQPARAVAEVGLLMDIVPGRKG
HCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TAVIDPYYGDEQDFEQAWADVSSAAEQIVRRFLR
CEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]