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The map label for this gene is ubiA

Identifier: 87198973

GI number: 87198973

Start: 997752

End: 998666

Strand: Direct

Name: ubiA

Synonym: Saro_0951

Alternate gene names: 87198973

Gene position: 997752-998666 (Clockwise)

Preceding gene: 87198969

Following gene: 87198976

Centisome position: 28.01

GC content: 68.63

Gene sequence:

>915_bases
ATGTCCGAGGTCAGTACGCAGCAGATCGTTCCCGACAGCGAGCACAAGGGGCTTGTCGCCCGCCTGCCGCAGCCTTGGCG
CAATCTTGCCCTGCTCGCCCGGTTCGATCGTCCGATCGGCTGGTGGTTGCTGTTCTGGCCCTGCGCCTGGGGCCTGTTCC
TCGGTGGCGGCACTTCGCGCTGGGGCATTCTGGCGTGGATGCTGCTCGGCGCGATTGCCATGCGCGGGGCGGGATGCGTC
TACAACGACATCGTCGATGCCGATCTCGATGCGCGCGTCGTCCGAACCGCCGCGCGCCCGGTCGCCAGCGGCGCCACGAG
CAAGCGGGCCGCGTGGATCTGGTTGCTCACGCTCTGCGCGGTGGGCCTCGTCGTGCTCCTGCAACTGCGCCGGGAAGCGC
AACTCGTGGCGATCGGCAGCCTTGCCCTCGTCGCCGCCTATCCCTTCATGAAGCGGATCACCGGATGGCCGCAGGCATGG
CTCGGCCTGGTCTTTACATGGGGCGCCCCGGTCGGTTGGGTCGAGGCCACCGGCTTCGACCGCCTCGGGCCGCTCGCTGC
GCTCTATGCCGGATGCTGGGCATGGTGCATGGCCTACGACACGATCTATGCCCTGCAGGATCGCGAGGACGATGCCATGG
TCGGCATCGGTTCTTCGGCGCTTTCGTTCGGCAGCTACGTACGCGCGGGCGTCGGCGGGCTTTATGCCATGGCGTTGCTG
TGCTGGGCGGGGGCGGTCTGGCTGGTCCGCGCCGATCCGCTGGCCCTGCTCGCGCTGCTCCCGGTCGCCTGCCACCTGGC
ATGGCAGGTGCTGACGCTGAAGGAAGACGGGGCGGACCCACTGGCCAAGTTCCGCTCAAACCGCTTCGCCGGTCTGCTGA
TGGCCGCGGCCTGCTATGTCGTGGGTGCGGCCTGA

Upstream 100 bases:

>100_bases
CGACGAACAGGCGCGGTGCGCTCTTCGGTGGCCAGGCGGGGGTGGCGGACATGATGATTTCGCGCCTAGCGCATTTCATC
TCACACGGTAAGGGTCGGAT

Downstream 100 bases:

>100_bases
TCGCCGAACAGCGCTTCGTGGCGCGCCTCTATCGCGGGCCACAGCGTGACGGCCTCGGGCACGTCGAGCAGGAACAGGTC
GCGCAACGCCTCGGCCAGTT

Product: 4-hydroxybenzoate polyprenyltransferase

Products: @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSEVSTQQIVPDSEHKGLVARLPQPWRNLALLARFDRPIGWWLLFWPCAWGLFLGGGTSRWGILAWMLLGAIAMRGAGCV
YNDIVDADLDARVVRTAARPVASGATSKRAAWIWLLTLCAVGLVVLLQLRREAQLVAIGSLALVAAYPFMKRITGWPQAW
LGLVFTWGAPVGWVEATGFDRLGPLAALYAGCWAWCMAYDTIYALQDREDDAMVGIGSSALSFGSYVRAGVGGLYAMALL
CWAGAVWLVRADPLALLALLPVACHLAWQVLTLKEDGADPLAKFRSNRFAGLLMAAACYVVGAA

Sequences:

>Translated_304_residues
MSEVSTQQIVPDSEHKGLVARLPQPWRNLALLARFDRPIGWWLLFWPCAWGLFLGGGTSRWGILAWMLLGAIAMRGAGCV
YNDIVDADLDARVVRTAARPVASGATSKRAAWIWLLTLCAVGLVVLLQLRREAQLVAIGSLALVAAYPFMKRITGWPQAW
LGLVFTWGAPVGWVEATGFDRLGPLAALYAGCWAWCMAYDTIYALQDREDDAMVGIGSSALSFGSYVRAGVGGLYAMALL
CWAGAVWLVRADPLALLALLPVACHLAWQVLTLKEDGADPLAKFRSNRFAGLLMAAACYVVGAA
>Mature_303_residues
SEVSTQQIVPDSEHKGLVARLPQPWRNLALLARFDRPIGWWLLFWPCAWGLFLGGGTSRWGILAWMLLGAIAMRGAGCVY
NDIVDADLDARVVRTAARPVASGATSKRAAWIWLLTLCAVGLVVLLQLRREAQLVAIGSLALVAAYPFMKRITGWPQAWL
GLVFTWGAPVGWVEATGFDRLGPLAALYAGCWAWCMAYDTIYALQDREDDAMVGIGSSALSFGSYVRAGVGGLYAMALLC
WAGAVWLVRADPLALLALLPVACHLAWQVLTLKEDGADPLAKFRSNRFAGLLMAAACYVVGAA

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=285, Percent_Identity=40, Blast_Score=170, Evalue=1e-42,
Organism=Escherichia coli, GI1790473, Length=206, Percent_Identity=39.3203883495146, Blast_Score=123, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17553718, Length=303, Percent_Identity=36.963696369637, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI32565247, Length=303, Percent_Identity=35.3135313531353, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17553720, Length=210, Percent_Identity=37.6190476190476, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32565245, Length=166, Percent_Identity=39.7590361445783, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI32565243, Length=162, Percent_Identity=39.5061728395062, Blast_Score=91, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6324370, Length=235, Percent_Identity=40.8510638297872, Blast_Score=158, Evalue=1e-39,
Organism=Drosophila melanogaster, GI21355567, Length=297, Percent_Identity=39.7306397306397, Blast_Score=191, Evalue=7e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 32868; Mature: 32737

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVSTQQIVPDSEHKGLVARLPQPWRNLALLARFDRPIGWWLLFWPCAWGLFLGGGTSR
CCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCH
WGILAWMLLGAIAMRGAGCVYNDIVDADLDARVVRTAARPVASGATSKRAAWIWLLTLCA
HHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
VGLVVLLQLRREAQLVAIGSLALVAAYPFMKRITGWPQAWLGLVFTWGAPVGWVEATGFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEECCCCC
RLGPLAALYAGCWAWCMAYDTIYALQDREDDAMVGIGSSALSFGSYVRAGVGGLYAMALL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHH
CWAGAVWLVRADPLALLALLPVACHLAWQVLTLKEDGADPLAKFRSNRFAGLLMAAACYV
HHHHHHEEEECCHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHCCCHHHHHHHHHHHH
VGAA
HCCC
>Mature Secondary Structure 
SEVSTQQIVPDSEHKGLVARLPQPWRNLALLARFDRPIGWWLLFWPCAWGLFLGGGTSR
CCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCH
WGILAWMLLGAIAMRGAGCVYNDIVDADLDARVVRTAARPVASGATSKRAAWIWLLTLCA
HHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
VGLVVLLQLRREAQLVAIGSLALVAAYPFMKRITGWPQAWLGLVFTWGAPVGWVEATGFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEECCCCC
RLGPLAALYAGCWAWCMAYDTIYALQDREDDAMVGIGSSALSFGSYVRAGVGGLYAMALL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHH
CWAGAVWLVRADPLALLALLPVACHLAWQVLTLKEDGADPLAKFRSNRFAGLLMAAACYV
HHHHHHEEEECCHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHCCCHHHHHHHHHHHH
VGAA
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-Hydroxybenzoate; Farnesylfarnesylgeraniol [C]

Specific reaction: 4-Hydroxybenzoate + Farnesylfarnesylgeraniol = @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA