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The map label for this gene is mcpA [H]

Identifier: 87198874

GI number: 87198874

Start: 902522

End: 904303

Strand: Direct

Name: mcpA [H]

Synonym: Saro_0852

Alternate gene names: 87198874

Gene position: 902522-904303 (Clockwise)

Preceding gene: 87198869

Following gene: 87198875

Centisome position: 25.34

GC content: 66.22

Gene sequence:

>1782_bases
ATGGCATTTCTTGGAAATCTCAAGATCAGGACAATTTCGATCGCCGGCAACCTGCTTCTCGGCCTGGCGGCCGTGGGTGG
CGGGATCGCTTCGGTGGTCGGCGTGGGGGCAATGAAGGAGCAGGTCGTCTTCATCGACGAGAACACCGTTCCGAGCATCG
CCCAGATCGGTGACGTTTCGATCGGCGTGATGGAAGCGCGCTTCGCCATGTCGAAGCTCATCCTCGCCTCGACGGATGTC
GCCCGGCAGGAGCAGGACGGCACGCTCAACGAGAAGAAGGCGGCTGTCGACAAGATGCTCGAGGATTACCGCGCCAATAT
ATCGGGCGATGAAGAGCAGAAGCTGTTCGACGCCGTCCTGGCAAGCTGGGACGACTGGAAGGCAACGGCTGGACCGATCC
GCCAACTGGCGATGCAGGCCCAGATCGATGAAGCGACGCTCAAGTTCAATGACGAACTCGGCCCGCGCGGCGCGGCTCTG
GCAAAAGCGCTGGATGCGCTGAGGGACTTCAACGTCAAGCTTGGCGGCGACGCCAGCGATGCGGCCGTCGCAGGTGCGAC
AAGCACCCGCAGCCTCGCGATGTCGGTCGCGGCCATTTCGGCGTTGATCGCCTCGCTCGTCGTCTTCCTGACCATTGTCC
GCATTGCCCGTCCGGTCGCGCAGCTGACCGCGGCGATGGAGGACATGGCTGGTGGCAACCTCGACCGCGACGTGCCCTTC
CGCGACCAGCCCGACGAAGTCGGCGGCATCGGTCGCGCGCTGGAATCGATCAAGGACAGCATTGCCCGCCGCACCCGCGA
GGAAGCCGAGCAGCGCATGGAAATCCAGCAGCGCATGGTTTCGGGCCTGGCACAGGGGCTTACCGCCCTTCGCGATGGTC
GCCTGAACTGCCGCATCGATCAGGCCTTCCCCGAGGAGTACGAAGGTCTGCGCCACGATTTCAACCAGACGATCGAATCG
CTGGCGGCGCTCATCGCGCAGGTCGTGCAGGGTTCGGGCAACGTCCGCACCGGGGCGAGCGAGATCGCCAGTGCTGCCGC
GGATCTTTCGGGCCGCACCGAAAGCCAGGCCGCAGCGCTGGAGGAATCGGCAGCAGCCGTCCGCCAGATCACCGACTCGC
TGCGTGAATCGGCCCATACCGCCAGCGAAGCCAGCAGCGTTGCCGGCGAAGCCCGCCGCGATGCCAGCGCCAGCGGCGAG
ATGATGGGCCGCGCCGTGAGCGCGATGGAGGAAATCGCCAAGTCGAGCGGCCGGATGGGCGAGATCGTCTCGCTGATCGA
GGGCATCGCCTTCCAGACCAACCTGCTCGCGCTCAACGCCGGCGTCGAAGCGGCCCGTGCGGGCGATGCCGGCAAGGGCT
TTGCCGTCGTCGCCAGCGAAGTCCGTGCGCTTGCCCAGCGTTCGGCCGAAGCCGCCAGCGAAATCACCGGCATCATCAAG
TCCAGCGAACGCGAAGTGGGCGACGGTGTGCAGGTGATCGGCCAGACTCAGGAAGCGCTCGACCAGATCGTCCGCCACAC
TGCGCGCCTGTCGGACATGATCGGAACGATTGCCGAGGCGACCAGCCAGCAGTCGGCGGCGATCAGCCAGGTCAACACCG
TCGTCGGCGACATGGACCGCATCACCCAGCAGAACGCCGCGCTTGTCGAGGAATCGACCGCAGCCTCGCAGAACCTCGCC
AATGCGGCGGGCACCCTGTCGCAGCTGGTCGAGCGCTTCGACCTGGGCGACAGCCGTGGCCGTGCCCCGGCACAGGCAGC
CCCGCGCCGCCTGGCCGCCTGA

Upstream 100 bases:

>100_bases
TTAGCCACTATTGCCGGCTTCCACCGCCCTTAACGGGCCGGGGTCCATGTCCATCGAGCATTGGCCGGAGTTTCCGGCAT
GGGACGCGAGGGCGTAAGTC

Downstream 100 bases:

>100_bases
TCGAAGCGACACGTCCGGACAGCGGGGCATGGCCATTGGCCGTGCCCCGTTTTCCATTCCGGCGATCAGCTATGTCGGGA
ATGGTGGGCGCGACAGGGAT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 593; Mature: 592

Protein sequence:

>593_residues
MAFLGNLKIRTISIAGNLLLGLAAVGGGIASVVGVGAMKEQVVFIDENTVPSIAQIGDVSIGVMEARFAMSKLILASTDV
ARQEQDGTLNEKKAAVDKMLEDYRANISGDEEQKLFDAVLASWDDWKATAGPIRQLAMQAQIDEATLKFNDELGPRGAAL
AKALDALRDFNVKLGGDASDAAVAGATSTRSLAMSVAAISALIASLVVFLTIVRIARPVAQLTAAMEDMAGGNLDRDVPF
RDQPDEVGGIGRALESIKDSIARRTREEAEQRMEIQQRMVSGLAQGLTALRDGRLNCRIDQAFPEEYEGLRHDFNQTIES
LAALIAQVVQGSGNVRTGASEIASAAADLSGRTESQAAALEESAAAVRQITDSLRESAHTASEASSVAGEARRDASASGE
MMGRAVSAMEEIAKSSGRMGEIVSLIEGIAFQTNLLALNAGVEAARAGDAGKGFAVVASEVRALAQRSAEAASEITGIIK
SSEREVGDGVQVIGQTQEALDQIVRHTARLSDMIGTIAEATSQQSAAISQVNTVVGDMDRITQQNAALVEESTAASQNLA
NAAGTLSQLVERFDLGDSRGRAPAQAAPRRLAA

Sequences:

>Translated_593_residues
MAFLGNLKIRTISIAGNLLLGLAAVGGGIASVVGVGAMKEQVVFIDENTVPSIAQIGDVSIGVMEARFAMSKLILASTDV
ARQEQDGTLNEKKAAVDKMLEDYRANISGDEEQKLFDAVLASWDDWKATAGPIRQLAMQAQIDEATLKFNDELGPRGAAL
AKALDALRDFNVKLGGDASDAAVAGATSTRSLAMSVAAISALIASLVVFLTIVRIARPVAQLTAAMEDMAGGNLDRDVPF
RDQPDEVGGIGRALESIKDSIARRTREEAEQRMEIQQRMVSGLAQGLTALRDGRLNCRIDQAFPEEYEGLRHDFNQTIES
LAALIAQVVQGSGNVRTGASEIASAAADLSGRTESQAAALEESAAAVRQITDSLRESAHTASEASSVAGEARRDASASGE
MMGRAVSAMEEIAKSSGRMGEIVSLIEGIAFQTNLLALNAGVEAARAGDAGKGFAVVASEVRALAQRSAEAASEITGIIK
SSEREVGDGVQVIGQTQEALDQIVRHTARLSDMIGTIAEATSQQSAAISQVNTVVGDMDRITQQNAALVEESTAASQNLA
NAAGTLSQLVERFDLGDSRGRAPAQAAPRRLAA
>Mature_592_residues
AFLGNLKIRTISIAGNLLLGLAAVGGGIASVVGVGAMKEQVVFIDENTVPSIAQIGDVSIGVMEARFAMSKLILASTDVA
RQEQDGTLNEKKAAVDKMLEDYRANISGDEEQKLFDAVLASWDDWKATAGPIRQLAMQAQIDEATLKFNDELGPRGAALA
KALDALRDFNVKLGGDASDAAVAGATSTRSLAMSVAAISALIASLVVFLTIVRIARPVAQLTAAMEDMAGGNLDRDVPFR
DQPDEVGGIGRALESIKDSIARRTREEAEQRMEIQQRMVSGLAQGLTALRDGRLNCRIDQAFPEEYEGLRHDFNQTIESL
AALIAQVVQGSGNVRTGASEIASAAADLSGRTESQAAALEESAAAVRQITDSLRESAHTASEASSVAGEARRDASASGEM
MGRAVSAMEEIAKSSGRMGEIVSLIEGIAFQTNLLALNAGVEAARAGDAGKGFAVVASEVRALAQRSAEAASEITGIIKS
SEREVGDGVQVIGQTQEALDQIVRHTARLSDMIGTIAEATSQQSAAISQVNTVVGDMDRITQQNAALVEESTAASQNLAN
AAGTLSQLVERFDLGDSRGRAPAQAAPRRLAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=257, Percent_Identity=45.5252918287938, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1787690, Length=312, Percent_Identity=41.025641025641, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1788195, Length=272, Percent_Identity=45.5882352941176, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI2367378, Length=306, Percent_Identity=43.7908496732026, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1789453, Length=233, Percent_Identity=39.4849785407725, Blast_Score=150, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 62015; Mature: 61884

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFLGNLKIRTISIAGNLLLGLAAVGGGIASVVGVGAMKEQVVFIDENTVPSIAQIGDVS
CCCCCCCEEEEEEEHHHHHHHHHHHCCHHHHHHHCCHHHCCEEEEECCCCCHHHHHCCCH
IGVMEARFAMSKLILASTDVARQEQDGTLNEKKAAVDKMLEDYRANISGDEEQKLFDAVL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
ASWDDWKATAGPIRQLAMQAQIDEATLKFNDELGPRGAALAKALDALRDFNVKLGGDASD
HCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCEECCCCCC
AAVAGATSTRSLAMSVAAISALIASLVVFLTIVRIARPVAQLTAAMEDMAGGNLDRDVPF
CHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
RDQPDEVGGIGRALESIKDSIARRTREEAEQRMEIQQRMVSGLAQGLTALRDGRLNCRID
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
QAFPEEYEGLRHDFNQTIESLAALIAQVVQGSGNVRTGASEIASAAADLSGRTESQAAAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHH
EESAAAVRQITDSLRESAHTASEASSVAGEARRDASASGEMMGRAVSAMEEIAKSSGRMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHH
EIVSLIEGIAFQTNLLALNAGVEAARAGDAGKGFAVVASEVRALAQRSAEAASEITGIIK
HHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSEREVGDGVQVIGQTQEALDQIVRHTARLSDMIGTIAEATSQQSAAISQVNTVVGDMDR
HCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITQQNAALVEESTAASQNLANAAGTLSQLVERFDLGDSRGRAPAQAAPRRLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHCCC
>Mature Secondary Structure 
AFLGNLKIRTISIAGNLLLGLAAVGGGIASVVGVGAMKEQVVFIDENTVPSIAQIGDVS
CCCCCCEEEEEEEHHHHHHHHHHHCCHHHHHHHCCHHHCCEEEEECCCCCHHHHHCCCH
IGVMEARFAMSKLILASTDVARQEQDGTLNEKKAAVDKMLEDYRANISGDEEQKLFDAVL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
ASWDDWKATAGPIRQLAMQAQIDEATLKFNDELGPRGAALAKALDALRDFNVKLGGDASD
HCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCEECCCCCC
AAVAGATSTRSLAMSVAAISALIASLVVFLTIVRIARPVAQLTAAMEDMAGGNLDRDVPF
CHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
RDQPDEVGGIGRALESIKDSIARRTREEAEQRMEIQQRMVSGLAQGLTALRDGRLNCRID
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
QAFPEEYEGLRHDFNQTIESLAALIAQVVQGSGNVRTGASEIASAAADLSGRTESQAAAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHH
EESAAAVRQITDSLRESAHTASEASSVAGEARRDASASGEMMGRAVSAMEEIAKSSGRMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHH
EIVSLIEGIAFQTNLLALNAGVEAARAGDAGKGFAVVASEVRALAQRSAEAASEITGIIK
HHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSEREVGDGVQVIGQTQEALDQIVRHTARLSDMIGTIAEATSQQSAAISQVNTVVGDMDR
HCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITQQNAALVEESTAASQNLANAAGTLSQLVERFDLGDSRGRAPAQAAPRRLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]