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The map label for this gene is tatA [H]

Identifier: 87198814

GI number: 87198814

Start: 840993

End: 842240

Strand: Direct

Name: tatA [H]

Synonym: Saro_0792

Alternate gene names: 87198814

Gene position: 840993-842240 (Clockwise)

Preceding gene: 87198813

Following gene: 87198817

Centisome position: 23.61

GC content: 66.19

Gene sequence:

>1248_bases
ATGCGGGGGTTGCCCCCGCCGCGTTCCGGCGGCATGGAGCCGCCGCATTTTGCTCCCCGCAATGGAAGGCCGCGACCAAT
GCTCGAAAATCTTGCCGCCCAGCCCGCCGACGCGCTGCTGGCGCTGATCAAGCTTCACAACGCCGATCCGCGCGAAGACA
AGATTGACCTTGGCGTCGGTGTCTATCGCACGTCCGAGGGCGCTACCCCTGTTTTCAAGGCGATCAAGGCGGCCGAGGCC
AAGCTGCTCGAAAGCCAGGATTCCAAGGCCTACCTCGGCCCCGAAGGCGACATGGGCTTCGTCCACGCGCTGATCCCCTA
TGTCTTCGGCAAGGACTTCGATCGTTCGAAGGTTGAGGGCATGCAGGCCCCCGGCGGCACCGGCGCGGTGCGCCTCGCCA
TCGAGGTGGCCAAGCGTTCGGGCGTCAAGCGGGTCTGGATGGGCACGCCTTCGTGGCCCAACCACGCGCAGATCATCGCT
GCTGCCGGCATGGAGCTGAAGACCTTCAGCCACATGACCGCCGACGGCCTTGCCGATCTCGAAGCATTGAAGACCGCCCT
GGCCGGTGCCGAAGCGGGCGATGCCGTCCTGCTCCACGGTTGCTGCCACAACCCCACAGGCGTCGACTATACCGAAGCCC
AGTGGGACGAGATCGCCCCGCTTCTGGTCGAGCGCCAGGTCCTGCCAATCCTCGACCTTGCCTACCAGGGGCTTGGCGCG
GGCATGGAAGCCGACGCCTATGGCCTGCGCAAGGTGCTCAGCCTCGCTCCGGAAGCGCTGGTCGCCTATTCGTGCGACAA
GAACTTCGGCCTCTATCGTGACCGCGTCGGCGCTTTCTATGCCGTCACGTCCGACGCCACCGCCCTGGCAAACGCCATGG
GCAACGGCGCGACGATCGCGCGCGCCTCGTGGTCGATGCCGCCCGATCATGGCGCCGCCGCCGTCCGCCTGATCCTCGAC
GATGCCGAGCTGACCGCAATGTGGCTGGCCGAGCTCGACGAGATGCGTGATCGCATGCGCTGGGTTCGCGATCGCCTTGC
CGCCGCGCAGCACGTCGGCCCGATCAACATGGCGCCGCTCGGCGTGCAGAACGGCCTGTTCTCGATGCTTCCGCTCAGGG
CCGACCAGATTCTCGCCATCCGCGAGAAGCACGGCGTCTACATGGCCGGTTCGGGACGCATCAACATTGCCGGCCTCACC
ACCGGTAACATCGACAAGTTCGTCGAAGCCCTGCGCGACGTCGCGTAA

Upstream 100 bases:

>100_bases
GGCGGCTACATGAAGTTCTCGCGCAAGCAGACCTGGTTCCCGTTCTGAGCCTTTCCGGCAATTTTCGGGCGAAATTCCCC
GCGCATACCTTCTAATTGAA

Downstream 100 bases:

>100_bases
GGTTTCAGTGAGCGGATAGAGAAAGGGCGGGGCCTCGCGGCTCCGCCCTTTTTTATTATCCGTGTGGGGTCGCAGCGCTC
AGAAATCCGCCGCCCTCGAC

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: TAT; L-tyrosine:2-oxoglutarate aminotransferase [H]

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MRGLPPPRSGGMEPPHFAPRNGRPRPMLENLAAQPADALLALIKLHNADPREDKIDLGVGVYRTSEGATPVFKAIKAAEA
KLLESQDSKAYLGPEGDMGFVHALIPYVFGKDFDRSKVEGMQAPGGTGAVRLAIEVAKRSGVKRVWMGTPSWPNHAQIIA
AAGMELKTFSHMTADGLADLEALKTALAGAEAGDAVLLHGCCHNPTGVDYTEAQWDEIAPLLVERQVLPILDLAYQGLGA
GMEADAYGLRKVLSLAPEALVAYSCDKNFGLYRDRVGAFYAVTSDATALANAMGNGATIARASWSMPPDHGAAAVRLILD
DAELTAMWLAELDEMRDRMRWVRDRLAAAQHVGPINMAPLGVQNGLFSMLPLRADQILAIREKHGVYMAGSGRINIAGLT
TGNIDKFVEALRDVA

Sequences:

>Translated_415_residues
MRGLPPPRSGGMEPPHFAPRNGRPRPMLENLAAQPADALLALIKLHNADPREDKIDLGVGVYRTSEGATPVFKAIKAAEA
KLLESQDSKAYLGPEGDMGFVHALIPYVFGKDFDRSKVEGMQAPGGTGAVRLAIEVAKRSGVKRVWMGTPSWPNHAQIIA
AAGMELKTFSHMTADGLADLEALKTALAGAEAGDAVLLHGCCHNPTGVDYTEAQWDEIAPLLVERQVLPILDLAYQGLGA
GMEADAYGLRKVLSLAPEALVAYSCDKNFGLYRDRVGAFYAVTSDATALANAMGNGATIARASWSMPPDHGAAAVRLILD
DAELTAMWLAELDEMRDRMRWVRDRLAAAQHVGPINMAPLGVQNGLFSMLPLRADQILAIREKHGVYMAGSGRINIAGLT
TGNIDKFVEALRDVA
>Mature_415_residues
MRGLPPPRSGGMEPPHFAPRNGRPRPMLENLAAQPADALLALIKLHNADPREDKIDLGVGVYRTSEGATPVFKAIKAAEA
KLLESQDSKAYLGPEGDMGFVHALIPYVFGKDFDRSKVEGMQAPGGTGAVRLAIEVAKRSGVKRVWMGTPSWPNHAQIIA
AAGMELKTFSHMTADGLADLEALKTALAGAEAGDAVLLHGCCHNPTGVDYTEAQWDEIAPLLVERQVLPILDLAYQGLGA
GMEADAYGLRKVLSLAPEALVAYSCDKNFGLYRDRVGAFYAVTSDATALANAMGNGATIARASWSMPPDHGAAAVRLILD
DAELTAMWLAELDEMRDRMRWVRDRLAAAQHVGPINMAPLGVQNGLFSMLPLRADQILAIREKHGVYMAGSGRINIAGLT
TGNIDKFVEALRDVA

Specific function: Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate [H]

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4504067, Length=409, Percent_Identity=33.2518337408313, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI73486658, Length=390, Percent_Identity=29.4871794871795, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI117414139, Length=385, Percent_Identity=24.1558441558442, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1787159, Length=392, Percent_Identity=42.6020408163265, Blast_Score=316, Evalue=2e-87,
Organism=Escherichia coli, GI1790488, Length=393, Percent_Identity=37.6590330788804, Blast_Score=262, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71981858, Length=398, Percent_Identity=32.9145728643216, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI25147133, Length=390, Percent_Identity=32.3076923076923, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17569539, Length=372, Percent_Identity=30.9139784946237, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17569537, Length=378, Percent_Identity=25.6613756613757, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17550384, Length=242, Percent_Identity=28.099173553719, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI25147136, Length=210, Percent_Identity=30.952380952381, Blast_Score=110, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6323055, Length=407, Percent_Identity=32.1867321867322, Blast_Score=192, Evalue=9e-50,
Organism=Saccharomyces cerevisiae, GI6322743, Length=422, Percent_Identity=28.1990521327014, Blast_Score=185, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24580972, Length=419, Percent_Identity=30.5489260143198, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI19920542, Length=397, Percent_Identity=31.4861460957179, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24580970, Length=397, Percent_Identity=31.4861460957179, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI19922362, Length=390, Percent_Identity=29.7435897435897, Blast_Score=185, Evalue=6e-47,
Organism=Drosophila melanogaster, GI24654046, Length=390, Percent_Identity=29.7435897435897, Blast_Score=184, Evalue=7e-47,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.5 [H]

Molecular weight: Translated: 44437; Mature: 44437

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGLPPPRSGGMEPPHFAPRNGRPRPMLENLAAQPADALLALIKLHNADPREDKIDLGVG
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEECCEE
VYRTSEGATPVFKAIKAAEAKLLESQDSKAYLGPEGDMGFVHALIPYVFGKDFDRSKVEG
EEECCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHCCCCCHHHHCC
MQAPGGTGAVRLAIEVAKRSGVKRVWMGTPSWPNHAQIIAAAGMELKTFSHMTADGLADL
CCCCCCCCCEEHHEEHHHHCCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHH
EALKTALAGAEAGDAVLLHGCCHNPTGVDYTEAQWDEIAPLLVERQVLPILDLAYQGLGA
HHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
GMEADAYGLRKVLSLAPEALVAYSCDKNFGLYRDRVGAFYAVTSDATALANAMGNGATIA
CCCCHHHHHHHHHHHCCHHHEEEECCCCCCCHHHCCCEEEEECCCHHHHHHHCCCCCEEE
RASWSMPPDHGAAAVRLILDDAELTAMWLAELDEMRDRMRWVRDRLAAAQHVGPINMAPL
EECCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GVQNGLFSMLPLRADQILAIREKHGVYMAGSGRINIAGLTTGNIDKFVEALRDVA
CCCCCHHHHHCCCCCCEEEEEHHCCEEEECCCEEEEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRGLPPPRSGGMEPPHFAPRNGRPRPMLENLAAQPADALLALIKLHNADPREDKIDLGVG
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEECCEE
VYRTSEGATPVFKAIKAAEAKLLESQDSKAYLGPEGDMGFVHALIPYVFGKDFDRSKVEG
EEECCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHCCCCCHHHHCC
MQAPGGTGAVRLAIEVAKRSGVKRVWMGTPSWPNHAQIIAAAGMELKTFSHMTADGLADL
CCCCCCCCCEEHHEEHHHHCCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHH
EALKTALAGAEAGDAVLLHGCCHNPTGVDYTEAQWDEIAPLLVERQVLPILDLAYQGLGA
HHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
GMEADAYGLRKVLSLAPEALVAYSCDKNFGLYRDRVGAFYAVTSDATALANAMGNGATIA
CCCCHHHHHHHHHHHCCHHHEEEECCCCCCCHHHCCCEEEEECCCHHHHHHHCCCCCEEE
RASWSMPPDHGAAAVRLILDDAELTAMWLAELDEMRDRMRWVRDRLAAAQHVGPINMAPL
EECCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GVQNGLFSMLPLRADQILAIREKHGVYMAGSGRINIAGLTTGNIDKFVEALRDVA
CCCCCHHHHHCCCCCCEEEEEHHCCEEEECCCEEEEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]